Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

The composition of the intestinal microbiota influences the development of inflammatory disorders. However, associating inflammatory diseases with specific microbial members of the microbiota is challenging, because clinically detectable inflammation and its treatment can alter the microbiota’s comp...

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Bibliographic Details
Published in:	Nature communications Vol. 7; no. 1; p. 10391
Main Authors:	Dubin, Krista, Callahan, Margaret K., Ren, Boyu, Khanin, Raya, Viale, Agnes, Ling, Lilan, No, Daniel, Gobourne, Asia, Littmann, Eric, Huttenhower, Curtis, Pamer, Eric G., Wolchok, Jedd D.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 02.02.2016 Nature Publishing Group Nature Portfolio
Subjects:	631/326/2565/2134 692/699/1503/1581/1392/1388 692/699/67/1059/2325 692/699/67/1813/1634 Adult Aged Aged, 80 and over Antibodies, Monoclonal - adverse effects Bacteroidaceae Bacteroidetes - genetics Bacteroidetes - isolation & purification Biosynthesis Colitis - chemically induced Colitis - microbiology Female Gastrointestinal Microbiome - genetics Humanities and Social Sciences Humans Immunotherapy Ipilimumab Lymphocytes Male Melanoma Melanoma - drug therapy Melanoma - secondary Middle Aged multidisciplinary Prospective Studies Risk Factors RNA, Ribosomal, 16S - genetics Science Science (multidisciplinary) Sequence Analysis, RNA Skin Neoplasms - drug therapy Skin Neoplasms - pathology
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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