Rapid determination and continuous monitoring of propofol in microliter whole blood sample during anesthesia by paper spray ionization-mass spectrometry

Propofol is a widely used intravenous anesthetic agent in sedation and general anesthesia. To improve the safety and maintain the depth of anesthesia, it is important to develop a rapid, sensitive, and reliable method to monitor the concentration of propofol in blood during anesthesia continuously....

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Vydané v:	Analytical and bioanalytical chemistry Ročník 413; číslo 1; s. 279 - 287
Hlavní autori:	Liu, Ying, Zhang, Xiao-Hui, Mi, Wei-Dong, Zhou, Ying-Lin, Zhang, Chang-Sheng, Zhang, Xin-Xiang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2021 Springer Springer Nature B.V
Predmet:	Analysis Analysis and chemistry Analytical Chemistry Anesthesia anesthetics Biochemistry Blood Blood levels blood sampling Characterization and Evaluation of Materials Chemical precipitation Chemistry Chemistry and Materials Science depth of anesthesia detection limit Food Science Intravenous administration intravenous injection Ionization Laboratory Medicine Mass spectrometry Mass spectroscopy Methanol Methods Monitoring Monitoring methods Monitoring/Environmental Analysis Observations Propofol Proteins Research Paper Scientific imaging sedation solvents Spectroscopy China Whole blood Ambient ionization mass spectrometry Propofol Monitoring in anesthesia Protein micro-precipitation
ISSN:	1618-2642, 1618-2650, 1618-2650
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