Pentoxifylline adjunct to risperidone for negative symptoms of stable schizophrenia: a randomized, double-blind, placebo-controlled trial

Abstract Background Negative symptoms of schizophrenia represent an unmet therapeutic need for many patients in whom pentoxifylline may be effective in terms of its dopaminergic, anti-inflammatory, and cerebral blood flow–increasing properties. This study aimed to evaluate pentoxifylline as a therap...

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Bibliographic Details
Published in:	The international journal of neuropsychopharmacology Vol. 28; no. 1; p. 1
Main Authors:	Shamabadi, Ahmad, Rafiei-Tabatabaei, Elham-Sadat, Kazemzadeh, Kimia, Farahmand, Kimia, Fallahpour, Bita, Khodaei Ardakani, Mohammad-Reza, Akhondzadeh, Shahin
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 01.01.2025
Subjects:	Adult Antipsychotic Agents - administration & dosage Antipsychotic Agents - adverse effects Antipsychotic Agents - pharmacology Dosage and administration Double-Blind Method Drug therapy Drug Therapy, Combination Female Humans Male Methods Middle Aged Outcome Assessment, Health Care Pentoxifylline Pentoxifylline - administration & dosage Pentoxifylline - adverse effects Pentoxifylline - pharmacology Psychiatric Status Rating Scales Regular Risperidone Risperidone - administration & dosage Risperidone - adverse effects Risperidone - pharmacology Schizophrenia Schizophrenia - drug therapy Schizophrenia - physiopathology Testing Treatment Outcome Young Adult Iran neuroimmunomodulation psychotic disorder combination drug therapy psychosis randomized controlled trial
ISSN:	1461-1457, 1469-5111, 1469-5111
Online Access:	Get full text
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