Plasma FABP4 is associated with liver disease recovery during treatment-induced clearance of chronic HCV infection

Direct-acting antivirals (DAAs) have dramatically improved the management of chronic hepatitis C (CHC). In this study, we investigated the effects of hepatitis C virus clearance on markers of systemic inflammation measured in plasma samples from CHC patients before, during and after DAA therapy. We...

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Bibliographic Details
Published in:	Scientific reports Vol. 10; no. 1; p. 2081
Main Authors:	Gorin, Jean-Baptiste, Malone, David F. G., Strunz, Benedikt, Carlsson, Tony, Aleman, Soo, Björkström, Niklas K., Falconer, Karolin, Sandberg, Johan K.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 07.02.2020 Nature Publishing Group
Subjects:	631/250/255/234/2513/1551 692/4020/4021/1607/234/2513/1551 82 82/1 Antiviral agents Antiviral Agents - therapeutic use Antiviral drugs CD163 antigen Cell activation Chronic infection Cirrhosis CXCL10 protein Cytokines - blood Fatty acid-binding protein Fatty Acid-Binding Proteins - blood Fatty Acid-Binding Proteins - metabolism Female Fibrosis Hepacivirus - drug effects Hepacivirus - metabolism Hepatitis Hepatitis C Hepatitis C, Chronic - blood Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - metabolism Hepatitis C, Chronic - pathology Humanities and Social Sciences Humans Immune clearance Inflammation Interferon Liver - pathology Liver - virology Liver cirrhosis Liver Cirrhosis - pathology Liver diseases Macrophages Male Middle Aged multidisciplinary Ribavirin Ribavirin - therapeutic use Science Science (multidisciplinary)
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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