The relationship between plasma serotonin and kynurenine pathway metabolite levels and the treatment response to escitalopram and desvenlafaxine

•Response to escitalopram was associated with higher baseline serotonin levels.•Response to escitalopram was associated with lower baseline Kyn/Trp ratio and quinolinic acid (QuinA)/tryptophan (Trp) ratio.•Remitters to escitalopram showed significant increases in KynA/3HK ratio. The response of pati...

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Vydané v:	Brain, behavior, and immunity Ročník 87; s. 404 - 412
Hlavní autori:	Sun, Yu, Drevets, Wayne, Turecki, Gustavo, Li, Qingqin S.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Netherlands Elsevier Inc 01.07.2020
Predmet:	Citalopram - therapeutic use Depressive Disorder, Major - drug therapy Desvenlafaxine Succinate Humans Kynurenic Acid Kynurenine Plasma Serotonin
ISSN:	0889-1591, 1090-2139, 1090-2139
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