An integrated genomic and transcriptomic survey of mucormycosis-causing fungi

Mucormycosis is a life-threatening infection caused by Mucorales fungi. Here we sequence 30 fungal genomes, and perform transcriptomics with three representative Rhizopus and Mucor strains and with human airway epithelial cells during fungal invasion, to reveal key host and fungal determinants contr...

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Bibliographic Details
Published in:	Nature communications Vol. 7; no. 1; pp. 12218 - 11
Main Authors:	Chibucos, Marcus C., Soliman, Sameh, Gebremariam, Teclegiorgis, Lee, Hongkyu, Daugherty, Sean, Orvis, Joshua, Shetty, Amol C., Crabtree, Jonathan, Hazen, Tracy H., Etienne, Kizee A., Kumari, Priti, O’Connor, Timothy D., Rasko, David A., Filler, Scott G., Fraser, Claire M., Lockhart, Shawn R., Skory, Christopher D., Ibrahim, Ashraf S., Bruno, Vincent M.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 22.07.2016 Nature Publishing Group Nature Portfolio
Subjects:	13/106 38/23 38/39 38/91 631/208/325/2484 631/326/193/2540 692/699/255/1672 96/95 A549 Cells Amidohydrolases - metabolism Amino Acid Sequence Animals Annotations Base Sequence Comparative analysis Debridement Disease Economic importance Fungal Proteins - chemistry Fungi Genes, Fungal Genome, Fungal Genomes Humanities and Social Sciences Humans Infections Male Medicine Mice, Inbred ICR Molecular Sequence Annotation Mortality Mucorales - enzymology Mucorales - genetics Mucorales - isolation & purification Mucormycosis - microbiology multidisciplinary Neutropenia Pathogenesis Phylogenetics Phylogeny Polymorphism, Single Nucleotide - genetics Rhizopus - genetics Science Science (multidisciplinary) Sequence Analysis, RNA Species Specificity Transcriptome - genetics Los Angeles California California United States > US Maryland Baltimore Maryland
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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