Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort

von Willebrand factor (VWF) is an essential component of hemostasis and has been implicated in thrombosis. Multimer size and the amount of circulating VWF are known to impact hemostatic function. We associated 78 VWF single nucleotide polymorphisms (SNPs) and haplotypes constructed from those SNPs w...

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Vydané v:	Blood Ročník 117; číslo 19; s. 5224
Hlavní autori:	Campos, Marco, Sun, Wei, Yu, Fuli, Barbalic, Maja, Tang, Weihong, Chambless, Lloyd E, Wu, Kenneth K, Ballantyne, Christie, Folsom, Aaron R, Boerwinkle, Eric, Dong, Jing-Fei
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 12.05.2011
Predmet:	Base Sequence Cohort Studies Genotype Haplotypes Humans Middle Aged Molecular Sequence Data Polymorphism, Single Nucleotide von Willebrand Factor - analysis von Willebrand Factor - genetics
ISSN:	1528-0020, 1528-0020
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