Immune Signature-Based Subtypes of Cervical Squamous Cell Carcinoma Tightly Associated with Human Papillomavirus Type 16 Expression, Molecular Features, and Clinical Outcome

Substantial heterogeneity exists within cervical cancer that is generally infected by human papillomavirus (HPV). However, the most common histological subtype of cervical cancer, cervical squamous cell carcinoma (CSCC), is poorly characterized regarding the association between its heterogeneity and...

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Vydáno v:	Neoplasia (New York, N.Y.) Ročník 21; číslo 6; s. 591 - 601
Hlavní autoři:	Lu, Xiaofan, Jiang, Liyun, Zhang, Liya, Zhu, Yue, Hu, Wenjun, Wang, Jiashuo, Ruan, Xinjia, Xu, Zhengbao, Meng, Xiaowei, Gao, Jun, Su, Xiaoping, Yan, Fangrong
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 01.06.2019 Elsevier
Témata:	Adult Carcinoma, Squamous Cell - classification Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - virology Class I Phosphatidylinositol 3-Kinases - genetics DNA Methylation - genetics F-Box-WD Repeat-Containing Protein 7 - genetics Female Gene Expression Regulation, Neoplastic - genetics Human papillomavirus 16 - genetics Human papillomavirus 16 - pathogenicity Humans Kaplan-Meier Estimate Keratin-1 - genetics Middle Aged Mucin-4 - genetics Oncogene Proteins, Viral - genetics Papillomavirus E7 Proteins - genetics Papillomavirus Infections - genetics Papillomavirus Infections - immunology Papillomavirus Infections - pathology Papillomavirus Infections - virology Progression-Free Survival Repressor Proteins - genetics Signal Transduction - genetics Uterine Cervical Neoplasms - classification Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - virology ρ CGI CI GO GSEA HR CESC FPKM TCGA HPV CSCC FDR IC50
ISSN:	1476-5586, 1476-5586
On-line přístup:	Získat plný text
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