Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth

Targeting protein-protein interactions (PPIs) is a promising approach in the development of drugs for many indications. 14-3-3 proteins are a family of phosphoprotein-binding molecules with critical functions in dozens of cell signaling networks. 14-3-3s are abundant in the central nervous system, a...

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Bibliographic Details

Published in:	Cell chemical biology Vol. 27; no. 6; p. 657
Main Authors:	Kaplan, Andrew, Andrei, Sebastian A, van Regteren Altena, Anna, Simas, Tristan, Banerjee, Sara L, Kato, Nobuo, Bisson, Nicolas, Higuchi, Yusuke, Ottmann, Christian, Fournier, Alyson E
Format:	Journal Article
Language:	English
Published:	United States 18.06.2020
Subjects:	14-3-3 spinal cord injury axon regeneration Rap1 polypharmacology
ISSN:	2451-9448, 2451-9448
Online Access:	Get more information
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