Guidelines for the welfare and use of animals in cancer research
Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of high quality cancer research. Here we provide updat...
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| Veröffentlicht in: | British journal of cancer Jg. 102; H. 11; S. 1555 - 1577 |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
London
Nature Publishing Group UK
25.05.2010
Nature Publishing Group |
| Schlagworte: | |
| ISSN: | 0007-0920, 1532-1827, 1532-1827 |
| Online-Zugang: | Volltext |
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| Abstract | Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of high quality cancer research. Here we provide updated guidelines on the welfare and use of animals in cancer research. All experiments should incorporate the 3Rs: replacement, reduction and refinement. Focusing on animal welfare, we present recommendations on all aspects of cancer research, including: study design, statistics and pilot studies; choice of tumour models (e.g., genetically engineered, orthotopic and metastatic); therapy (including drugs and radiation); imaging (covering techniques, anaesthesia and restraint); humane endpoints (including tumour burden and site); and publication of best practice. |
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| AbstractList | Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of high quality cancer research. Here we provide updated guidelines on the welfare and use of animals in cancer research. All experiments should incorporate the 3Rs: replacement, reduction and refinement. Focusing on animal welfare, we present recommendations on all aspects of cancer research, including: study design, statistics and pilot studies; choice of tumour models (e.g., genetically engineered, orthotopic and metastatic); therapy (including drugs and radiation); imaging (covering techniques, anaesthesia and restraint); humane endpoints (including tumour burden and site); and publication of best practice. Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of high quality cancer research. Here we provide updated guidelines on the welfare and use of animals in cancer research. All experiments should incorporate the 3Rs: replacement, reduction and refinement. Focusing on animal welfare, we present recommendations on all aspects of cancer research, including: study design, statistics and pilot studies; choice of tumour models (e.g., genetically engineered, orthotopic and metastatic); therapy (including drugs and radiation); imaging (covering techniques, anaesthesia and restraint); humane endpoints (including tumour burden and site); and publication of best practice.Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer. Excellent standards of animal care are fully consistent with the conduct of high quality cancer research. Here we provide updated guidelines on the welfare and use of animals in cancer research. All experiments should incorporate the 3Rs: replacement, reduction and refinement. Focusing on animal welfare, we present recommendations on all aspects of cancer research, including: study design, statistics and pilot studies; choice of tumour models (e.g., genetically engineered, orthotopic and metastatic); therapy (including drugs and radiation); imaging (covering techniques, anaesthesia and restraint); humane endpoints (including tumour burden and site); and publication of best practice. |
| Author | Double, J A Glennie, M J Balmain, A Eccles, S A Watson, S Bruder, G Aboagye, E O Kelland, L R Everitt, J Chaplin, D J Robinson, V Tozer, G M Wedge, S R Balkwill, F Workman, P Farningham, D A H Stratford, I J |
| Author_xml | – sequence: 1 givenname: P surname: Workman fullname: Workman, P email: Paul.Workman@icr.ac.uk organization: Cancer Research UK Centre for Cancer Therapeutics, The Institute of Cancer Research – sequence: 2 givenname: E O surname: Aboagye fullname: Aboagye, E O organization: Comprehensive Cancer Imaging Centre, Imperial College London Faculty of Medicine, Hammersmith Hospital Campus – sequence: 3 givenname: F surname: Balkwill fullname: Balkwill, F organization: Centre for Cancer & Inflammation, Barts and The London School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square – sequence: 4 givenname: A surname: Balmain fullname: Balmain, A organization: Helen Diller Family Comprehensive Cancer Center, University of California San Francisco 1450 3rd Street – sequence: 5 givenname: G surname: Bruder fullname: Bruder, G organization: Paterson Institute for Cancer Research, University of Manchester – sequence: 6 givenname: D J surname: Chaplin fullname: Chaplin, D J organization: OXiGENE Inc., 701 Gateway Boulevard – sequence: 7 givenname: J A surname: Double fullname: Double, J A organization: University of Bradford – sequence: 8 givenname: J surname: Everitt fullname: Everitt, J organization: GlaxoSmithkline Pharmaceutical R&D, PO Box 13398, Five Moore Drive, N2.2210.2B – sequence: 9 givenname: D A H surname: Farningham fullname: Farningham, D A H organization: Cancer Research UK, Clare Hall Laboratories, Blanche Lane, South Mimms, Current address: Medical Research Council, 20 Park Crescent London W1B 1AL, UK – sequence: 10 givenname: M J surname: Glennie fullname: Glennie, M J organization: Cancer Sciences Division, Tenovus Laboratory, Southampton University School of Medicine, General Hospital – sequence: 11 givenname: L R surname: Kelland fullname: Kelland, L R organization: Cancer Research Technology Development Laboratories, Wolfson Institute for Biomedical Research, University College London – sequence: 12 givenname: V surname: Robinson fullname: Robinson, V organization: National Centre for the Replacement, Refinement and Reduction of Animals in Research 20, Park Crescent – sequence: 13 givenname: I J surname: Stratford fullname: Stratford, I J organization: School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Stopford Building – sequence: 14 givenname: G M surname: Tozer fullname: Tozer, G M organization: Department of Oncology, K Floor, School of Medicine, University of Sheffield – sequence: 15 givenname: S surname: Watson fullname: Watson, S organization: Division of Pre-Clinical Oncology & PRECOS, D Floor West Block, Queen's Medical Centre, University Hospital – sequence: 16 givenname: S R surname: Wedge fullname: Wedge, S R organization: Cancer Bioscience, AstraZeneca, Mereside, Alderley Park, Macclesfield – sequence: 17 givenname: S A surname: Eccles fullname: Eccles, S A email: Sue.Eccles@icr.ac.uk organization: Cancer Research UK Centre for Cancer Therapeutics, The Institute of Cancer Research |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22999926$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/20502460$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1158/1535-7163.MCT-06-0324 10.1038/nature07943 10.1162/1535350042380326 10.1073/pnas.121616198 10.1093/jnci/djj381 10.1128/MCB.12.3.954 10.1046/j.1365-2141.1996.4941035.x 10.1073/pnas.242594299 10.1017/S0317167100003036 10.1126/science.284.5415.808 10.1016/S0092-8674(00)81683-9 10.1101/gad.12.11.1599 10.1016/j.ejmech.2007.04.009 10.1111/j.1471-4159.2008.05730.x 10.1136/gut.45.6.812 10.1016/S0959-8049(99)00115-X 10.1016/j.ccr.2004.05.025 10.1038/ng1572 10.2174/1389200023337135 10.2144/02322rr05 10.1038/nrd2110 10.1016/j.ccr.2005.04.023 10.1016/j.jneumeth.2005.04.011 10.1007/BF01806077 10.2351/1.4745330 10.1080/10611860802230372 10.1101/gad.14.13.1617 10.1007/s10911-008-9087-3 10.2174/138620710790596745 10.1290/0505035.1 10.1158/0008-5472.CAN-04-3118 10.1007/s00262-004-0553-5 10.1073/pnas.93.7.2702 10.1038/nchembio840 10.1002/sim.1775 10.1053/j.gastro.2009.01.006 10.1242/dmm.003681 10.1016/0022-1759(94)90108-2 10.1093/carcin/20.9.1801 10.1111/j.1749-6632.1999.tb08722.x 10.1038/35074129 10.1038/nature06188 10.1177/026119290503300207 10.1007/s10911-008-9089-1 10.1093/ilar.43.4.244 10.1158/1078-0432.CCR-07-5090 10.1177/0192623308329281 10.1016/S0959-8049(02)00410-0 10.1007/s11060-007-9442-z 10.1016/S0301-472X(00)00669-X 10.1128/CDLI.7.2.141-144.2000 10.1016/S0169-409X(00)00128-9 10.1038/nrc1717 10.1158/0008-5472.CAN-07-6656 10.2174/1386207013331101 10.1093/ilar.43.2.100 10.1158/0008-5472.CAN-05-3827 10.1002/ijc.1638 10.1038/clpt.2008.200 10.1016/j.drup.2007.11.002 10.1038/nrc2192 10.1093/bja/aen087 10.1038/nrc1231 10.1007/s10103-006-0395-9 10.1016/j.ejca.2003.11.029 10.1097/00002371-200111000-00004 10.1016/j.pbiomolbio.2006.02.024 10.1111/j.1600-0609.2006.00686.x 10.1038/8743 10.1007/BF00305296 10.1016/j.jchromb.2008.05.025 10.1016/j.peptides.2007.04.015 10.1007/s10585-005-5261-9 10.2307/3577110 10.1038/89997 10.4142/jvs.2001.2.1.53 10.1158/1078-0432.CCR-06-0918 10.1667/RR1911.1 10.1111/j.1349-7006.2006.00190.x 10.1210/endo-82-5-1049 10.1002/ijc.23233 10.1016/j.aca.2005.11.049 10.1023/A:1006104220315 10.1002/1097-0142(20000615)88:12+<2995::AID-CNCR15>3.0.CO;2-Y 10.1038/35092584 10.1158/1078-0432.CCR-1004-0004 10.1038/sj.bjc.6604238 10.1203/01.PDR.0000147727.78571.07 10.1038/sj.neo.7900005 10.1016/j.cell.2005.02.034 10.2188/jea.9.6sup_58 10.3748/wjg.v13.i30.4131 10.1158/0008-5472.CAN-04-0106 10.1158/0008-5472.CAN-05-3627 10.1101/gad.1158703 10.1007/s10565-007-9019-9 10.1158/1940-6207.CAPR-09-0081 10.1093/emboj/16.11.2985 10.1038/bjc.1988.174 10.1093/carcin/bgg156 10.1096/fj.08-126920 10.1016/0092-8674(87)90449-1 10.1002/hep.21291 10.1007/s11307-007-0080-9 10.1093/jnci/83.9.627 10.1158/0008-5472.CAN-09-1689 10.1038/442739a 10.1038/nature05077 10.1158/0008-5472.CAN-08-0135 10.1038/bjc.1993.453 10.1158/1078-0432.CCR-06-2553 10.1038/sj.bjc.6690337 10.1111/j.1440-1746.2004.03469.x 10.1016/j.jpedsurg.2007.02.027 10.1016/S1097-2765(00)80350-0 10.1038/nbt0705-790 10.1002/jps.21494 10.1016/j.bbrc.2005.05.106 10.1016/S0301-472X(01)00759-7 10.1021/mp070019+ 10.1080/08958370390228592 10.1007/s10585-008-9234-7 10.1038/sj.onc.1209482 10.1007/s002800051098 10.1093/carcin/bgh059 10.1016/j.neuroimage.2008.12.022 10.1016/S1097-2765(00)80367-6 10.1080/10739680701436350 10.1093/ilar.43.4.191 10.1038/nrc2289 10.1016/j.ejca.2003.11.028 10.1038/nature06917 10.3748/wjg.v11.i22.3335 10.1158/1078-0432.CCR-09-2878 10.1200/JCO.2003.05.187 10.1093/jnci/djj162 10.3109/03602539709002237 10.1038/nature03095 10.1101/gad.1771409 10.1021/ci0504014 10.1038/79075 10.1158/0008-5472.CAN-04-0986 10.1073/pnas.0901310106 10.1101/gad.1417406 10.3945/jn.109.111864 10.1002/ijc.10215 10.3171/JNS/2008/108/2/0304 10.1021/jm060230+ 10.1038/onc.2009.250 10.1038/nature08768 10.1126/science.278.5335.120 10.1016/j.mri.2005.09.006 10.1111/j.1749-0774.2005.00007.x 10.1021/ac0709798 10.1111/j.1349-7006.1999.tb00697.x 10.1038/nature07260 10.1007/s00280-002-0529-0 10.1093/carcin/bgp238 10.2174/138920006775541552 10.1038/35020592 10.1182/blood-2003-08-2911 10.1097/00001813-199902000-00012 10.1038/nrc2771 10.1016/j.bmc.2008.05.021 10.1038/ng747 10.1016/j.coph.2008.07.007 10.1158/1078-0432.CCR-05-0518 10.1258/0023677011911345 10.1038/nrc2622 10.1002/jat.727 10.1258/002367704323133673 10.1002/(SICI)1097-0215(19980812)77:4<640::AID-IJC26>3.0.CO;2-8 10.1385/IR:29:1-3:269 10.1080/15265160903318343 10.1124/pr.58.3.10 10.1158/1535-7163.MCT-09-0743 10.1016/0360-3016(92)90856-D 10.1055/s-2008-1043947 10.1371/journal.pone.0004992 10.1038/nm1087 10.1258/002367706776318971 |
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| Copyright | The Author(s) 2010 2015 INIST-CNRS Copyright Nature Publishing Group May 25, 2010 Copyright © 2010 Cancer Research UK 2010 Cancer Research UK |
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| ISSN | 0007-0920 1532-1827 |
| IngestDate | Tue Nov 04 01:58:05 EST 2025 Sun Nov 09 11:55:09 EST 2025 Mon Oct 06 18:18:18 EDT 2025 Sat May 31 02:09:21 EDT 2025 Mon Jul 21 09:16:38 EDT 2025 Sat Nov 29 08:17:12 EST 2025 Tue Nov 18 21:42:03 EST 2025 Fri Feb 21 02:38:28 EST 2025 |
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| Issue | 11 |
| Keywords | animal welfare drugs therapy orthotopic models fundamental and translational research tumour models imaging cancer research humane endpoints metastatic models restraint tumour burden imaging techniques pharmocokinetic, pharmacodynamic and efficacy studies pilot studies radiation therapy publication replacement, reduction and refinement (3Rs) genetically engineered mouse models human tumour xenografts clinical signs best practice anaesthesia Metastasis Heterotransplantation pharmocokinetic Surgery Graft Genetics pharmacodynamic and efficacy studies Human Pharmacodynamics Orthotopic Treatment efficiency Rodentia Radiotherapy Recommendation Vertebrata Animal Technique replacement Animal model Refinement Transplantation Prevention Cancerology Advanced stage Fundamental research Drug reduction and refinement (3Rs) Malignant tumor Mammalia Treatment Mouse Medical imagery Cancer |
| Language | English |
| License | http://www.springer.com/tdm CC BY 4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0 |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Instructional Material/Guideline-3 content type line 23 The National Cancer Research Institute (NCRI) is a partnership of 21 organisations from the government, charity and commercial sectors who support cancer research in the UK. Further information about NCRI can be found at http://www.ncri.org.uk Observers: V Navaratnam and S Ryder17 |
| OpenAccessLink | https://pubmed.ncbi.nlm.nih.gov/PMC2883160 |
| PMID | 20502460 |
| PQID | 346148129 |
| PQPubID | 41855 |
| PageCount | 23 |
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| PublicationCentury | 2000 |
| PublicationDate | 2010-05-25 |
| PublicationDateYYYYMMDD | 2010-05-25 |
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| PublicationDecade | 2010 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: Basingstoke – name: England |
| PublicationTitle | British journal of cancer |
| PublicationTitleAbbrev | Br J Cancer |
| PublicationTitleAlternate | Br J Cancer |
| PublicationYear | 2010 |
| Publisher | Nature Publishing Group UK Nature Publishing Group |
| Publisher_xml | – name: Nature Publishing Group UK – name: Nature Publishing Group |
| References | De Fabo (CR37) 2006; 92 Qian, Furge, Knol, Huang, Chen, Dykema, Kort, Massie, Khoo, Vanden Beldt, Resau, Anema, Kahnoski, Morreau, Camparo, Comperat, Sibony, Denoux, Molinie, Vieillefond, Eng, Williams, Teh (CR143) 2009; 69 Kenerson, Dundon, Yeung (CR92) 2005; 57 Huxham, Kyle, Baker, Nykilchuk, Minchinton (CR82) 2004; 64 Blouin, Basle, Chappard (CR17) 2008; 98 Kennel, Boll, Stabin, Schuller, Mirzadeh (CR93) 1999; 80 Siim, Lee, Shalal-Zwain, Pruijn, McKeage, Wilson (CR169) 2003; 51 CR156 Warden, Bennell, McMeeken, Wark (CR191) 2000; 39 Dickson, Hamner, Ng, Hall, Zhou, Hargrove, McCarville, Davidoff (CR42) 2007; 42 Tsai, Stelzer, Schraepler, Hackbarth (CR183) 2006; 23 Liem, Papa, Milross, Schmid, Tajbakhsh, Choi, Ramirez, Rice, Haber, Norris, MacKenzie, Lock (CR105) 2004; 103 Kato, Kobayashi, Villec (CR90) 1968; 82 Nordsmark, Maxwell, Wood, Stratford, Adams, Overgaard, Horsman (CR128) 1996; 27 Roughan, Flecknell, Davies (CR155) 2004; 38 Condeelis, Segall (CR35) 2003; 3 Giovannini, Robanus-Maandag, van der Valk, Niwa-Kawakita, Abramowski, Goutebroze, Woodruff, Berns, Thomas (CR60) 2000; 14 Christophorou, Ringshausen, Finch, Swigart, Evan (CR30) 2006; 443 Xu, Wagner, Larson, Weaver, Li, Ried, Hennighausen, Wynshaw-Boris, Deng (CR206) 1999; 22 Serganova, Moroz, Vider, Gogiberidze, Moroz, Pillarsetty, Doubrovin, Minn, Thaler, Massague, Gelovani, Blasberg (CR164) 2009; 23 Fluck, Haslam (CR54) 1996; 39 Kim, Shin, Park, Hong, Shin, Kim, Kwon, Park (CR94) 2009; 139 Pearse, Frith, Randall, Klinowska (CR136) 2009; 37 Hirose, Hata, Kuno, Yoshida, Sakata, Yamada, Tanaka, Reddy, Mori (CR77) 2004; 25 Li, Chen, Lu, Cen, He, Chen, Xue, Guo (CR104) 2006; 77 Tan, Fang, Tian, Houghton (CR180) 2005; 24 Banerji, Walton, Raynaud, Grimshaw, Kelland, Valenti, Judson, Workman (CR9) 2005; 11 Houston, Carlile (CR80) 1997; 29 Frese, Tuveson (CR56) 2007; 7 Lifsted, Le Voyer, Williams, Muller, Klein-Szanto, Buetow, Hunter (CR106) 1998; 77 Garber (CR59) 2006; 98 Glass, Uharek, Zeis, Loeffler, Mueller-Ruchholtz, Gassmann (CR62) 1996; 93 Neale, Su, Morton, Phelps, Gorlick, Lock, Reynolds, Maris, Friedman, Dome, Khoury, Triche, Seeger, Gilbertson, Khan, Smith, Houghton (CR123) 2008; 14 Smith, Raynaud, Workman (CR172) 2007; 6 Paulmurugan, Umezawa, Gambhir (CR135) 2002; 99 Yang, Mao, Cao, Wang, Peng, Wang, Sajja, Wang, Duan, Ni, Staley, Wood, Gao, Nie (CR207) 2009; 136 Watanabe, Schulz, Morisseau, Hammock (CR193) 2006; 559 Martensson, Wang, Nilsson, Ohlsson, Senter, Sjogren, Strand, Tennvall (CR111) 2005; 11 Brown, Campbell, Tsuzuki, Xu, Carmeliet, Fukumura, Jain (CR20) 2001; 7 Kelland (CR91) 2004; 40 Ihle, Lemos, Wipf, Yacoub, Mitchell, Siwak, Mills, Dent, Kirkpatrick, Powis (CR83) 2009; 69 Komatsubara, Umeda, Ojima, Minamikawa, Komori (CR97) 2005; 51 Osborne, Payne, Newman (CR130) 2009; 9 Becher, Holland, Sausville, Burger (CR13) 2006; 66 Stratton, Campbell, Futreal (CR176) 2009; 458 Zhu, Song, Chen, Li, Sun, Zhang (CR214) 2007; 13 Nijmeijer, Mollevanger, van Zelderen-Bhola, Kluin-Nelemans, Willemze, Falkenburg (CR126) 2001; 29 Robanus-Maandag, Dekker, van der Valk, Carrozza, Jeanny, Dannenberg, Berns, te Riele (CR152) 1998; 12 Rottenberg, Jonkers (CR154) 2008; 11 Lacroix (CR100) 2008; 122 Morton, Jennings, Buckwell, Ewbank, Godfrey, Holgate, Inglis, James, Page, Sharman, Verschoyle, Westall, Wilson (CR118) 2001; 35 Yoshino, Iimura, Saijo, Iwase, Fukami, Ohno, Obata, Nakamura (CR210) 2006; 19 Bignell, Greenman, Davies, Butler, Edkins, Andrews, Buck, Chen, Beare, Latimer, Widaa, Hinton, Fahey, Fu, Swamy, Dalgliesh, Teh, Deloukas, Yang, Campbell, Futreal, Stratton (CR16) 2010; 463 Jackson, Vujaskovic, Down (CR85) 2010; 173 Vogelstein, Kinzler (CR190) 2004; 10 Sausville, Burger, Becher, Holland (CR162) 2006; 66 Alsheikhly, Zweiri, Walmesley, Watson, Christmas (CR4) 2004; 53 Watanabe, Uesaka, Kido, Ishimura, Shiraki, Kuramoto, Hirata, Shoji, Katoh, Fujimoto (CR192) 1999; 90 Koehl, Gaumann, Geissler (CR96) 2009; 26 Lock, Liem, Papa (CR107) 2005; 111 Glinskii, Smith, Jiang, Li, Yang, Hoffman, Glinsky (CR63) 2003; 63 Hoffman (CR78) 2005; 5 Radaelli, Ceruti, Patton, Russo, Degrassi, Croci, Caprera, Stortini, Scanziani, Pesenti, Alzani (CR145) 2009; 24 Ullman-Cullere, Foltz (CR185) 1999; 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35 Golay, Cittera, Di Gaetano, Manganini, Mosca, Nebuloni, van Rooijen, Vago, Introna (CR64) 2006; 91 Workman, Aboagye, Chung, Griffiths, Hart, Leach, Maxwell, McSheehy, Price, Zweit (CR203) 2006; 98 Gajewski (CR57) 2000; 7 Colclough, Hunter, Kenny, Kittlety, Lobedan, Tam, Timms (CR31) 2008; 16 Dennis (CR39) 2006; 17 Prigozhina, Gurevitch, Morecki, Yakovlev, Elkin, Slavin (CR142) 2002; 30 Miyazaki, Koshikawa, Hasegawa, Momiyama, Nagashima, Moriyama, Ichikawa, Ishikawa, Mitsuhashi, Shimada (CR117) 1999; 43 Orimo, Gupta, Sgroi, Arenzana-Seisdedos, Delaunay, Naeem, Carey, Richardson, Weinberg (CR129) 2005; 121 Yang, Reynoso, Jiang, Li, Moossa, Hoffman (CR208) 2004; 64 Narciso, Nadziejko, Chen, Gordon, Nadziejko (CR121) 2003; 15 Han, Chen, Huang, Zhu (CR69) 2005; 11 Tanaka, Konno, Matsuda, Nakamura, Baba (CR181) 1995; 55 Christophorou, Martin-Zanca, Soucek, Lawlor, Brown-Swigart, Verschuren, Evan (CR29) 2005; 37 McCann, Waterman, Figueiredo, Aikawa, Weissleder, Chen (CR115) 2009; 45 Johansen, Vestergaard, Kragballe, Kollias, Gaestel, Iversen (CR86) 2009; 30 Zhau, Li, Chung (CR212) 2000; 88 Poller, Gutmann, Krahenbuhl, Weksler, Romero, Couraud, Tuffin, Drewe, Huwyler (CR141) 2008; 107 Chen, Yang, Ding, Bondoc, Curtis, Yang (CR27) 1999; 20 Politi, Zakowski, Fan, Schonfeld, Pao, Varmus (CR140) 2006; 20 Becker, Pancook, Gillies, Mendelsohn, Reisfeld (CR14) 1996; 93 van Kranen, de Gruijl (CR187) 1999; 9 Zuber, Radtke, Pardee, Zhao, Rappaport, Luo, McCurrach, Yang, Dolan, Kogan, Downing, Lowe (CR216) 2009; 23 Collado, Carmena, Clemente, Prieto, Bajo (CR32) 2007; 28 Artursson, Palm, Luthman (CR6) 2001; 46 Zheng, Chen, Shi, Xiao (CR213) 2004; 19 Harlin, Gajewski (CR71) 2008; Appendix 3 Pillai, Forster, Perumal, Mitchell, Leyton, Aibgirhio, Golovko, Jackman, Aboagye (CR138) 2008; 68 Howard, Hill, Galluppi, McLean (CR81) 2010; 13 Spaeth, Dembinski, Sasser, Watson, Klopp, Hall, Andreeff, Marini (CR174) 2009; 4 Nakatsugawa, Okuda, Muramoto, Koyama, Ishigaki, Tsuruoka, Hosokawa, Kobayashi (CR120) 1999; 10 Soucek, Whitfield, Martins, Finch, Murphy, Sodir, Karnezis, Swigart, Nasi, Evan (CR173) 2008; 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97 CL Zavaleta (BF6605642_CR211) 2008; 16 LA Huxham (BF6605642_CR82) 2004; 64 D Hanahan (BF6605642_CR70) 2000; 100 U Banerji (BF6605642_CR9) 2005; 11 MM Fluck (BF6605642_CR54) 1996; 39 K Miyazaki (BF6605642_CR117) 1999; 43 H Shibata (BF6605642_CR167) 1997; 278 MM Taketo (BF6605642_CR179) 2006; 97 BF6605642_CR156 CR Giver (BF6605642_CR61) 2004; 29 S Nakatsugawa (BF6605642_CR120) 1999; 10 H Harlin (BF6605642_CR71) 2008; Appendix 3 DA Tennant (BF6605642_CR182) 2009; 28 RG Pillai (BF6605642_CR138) 2008; 68 J Kato (BF6605642_CR90) 1968; 82 PJ Russell (BF6605642_CR159) 1991; 19 M Nordsmark (BF6605642_CR128) 1996; 27 IL Jackson (BF6605642_CR85) 2010; 173 M Kragh (BF6605642_CR98) 2003; 22 K Brindle (BF6605642_CR19) 2008; 8 EC De Fabo (BF6605642_CR37) 2006; 92 RM Hoffman (BF6605642_CR79) 2005; 23 K Politi (BF6605642_CR140) 2006; 20 C Johansen (BF6605642_CR86) 2009; 30 SJ Warden (BF6605642_CR191) 2000; 39 ML Howard (BF6605642_CR81) 2010; 13 J Jonkers (BF6605642_CR88) 2001; 29 P Flecknell (BF6605642_CR53) 2008; 101 OJ Becher (BF6605642_CR13) 2006; 66 EB Brown (BF6605642_CR20) 2001; 7 G Pearse (BF6605642_CR136) 2009; 37 X Chen (BF6605642_CR27) 1999; 20 B Glass (BF6605642_CR62) 1996; 93 W Yang (BF6605642_CR209) 2001; 61 MA Christophorou (BF6605642_CR29) 2005; 37 JB Houston (BF6605642_CR80) 1997; 29 TB Prigozhina (BF6605642_CR142) 2002; 30 H Watanabe (BF6605642_CR192) 1999; 90 CN Qian (BF6605642_CR143) 2009; 69 PV Dickson (BF6605642_CR42) 2007; 42 LR Kelland (BF6605642_CR91) 2004; 40 DW Felsher (BF6605642_CR49) 1999; 4 L Martensson (BF6605642_CR111) 2005; 11 P Workman (BF6605642_CR204) 2008; 8 KE Comstock (BF6605642_CR34) 2009; 23 C Dennis (BF6605642_CR39) 2006; 17 A Zisman (BF6605642_CR215) 2003; 63 EJ Freireich (BF6605642_CR55) 1966; 50 PP Tsai (BF6605642_CR183) 2006; 23 B Vogelstein (BF6605642_CR190) 2004; 10 WR van Furth (BF6605642_CR186) 2003; 30 SE Artandi (BF6605642_CR5) 2000; 406 WS Ha (BF6605642_CR68) 2001; 2 R Bazin (BF6605642_CR11) 1994; 172 RM Balansky (BF6605642_CR8) 2002; 98 B Collado (BF6605642_CR32) 2007; 28 A Noel (BF6605642_CR127) 1993; 68 SM Galbraith (BF6605642_CR58) 2003; 21 RJ Riley (BF6605642_CR151) 2002; 3 DB Morton (BF6605642_CR118) 2001; 35 NJ Osborne (BF6605642_CR130) 2009; 9 AB Glinskii (BF6605642_CR63) 2003; 63 S Decker (BF6605642_CR38) 2004; 40 M Festing (BF6605642_CR50) 2002 JV Roughan (BF6605642_CR155) 2004; 38 R Weissleder (BF6605642_CR197) 2008; 452 TF Gajewski (BF6605642_CR57) 2000; 7 MA Shibata (BF6605642_CR168) 2009; 29 D Rusciano (BF6605642_CR158) 1994; 14 Y Ishikawa (BF6605642_CR84) 2006; 42 SA Watson (BF6605642_CR195) 1999; 45 20502459 - Br J Cancer. 2010 May 25;102(11):1553-4. doi: 10.1038/sj.bjc.6605692. |
| References_xml | – volume: 13 start-page: 323 year: 2008 end-page: 335 ident: CR110 article-title: Signal transduction in transgenic mouse models of human breast cancer – implications for human breast cancer publication-title: J Mammary Gland Biol Neoplasia – volume: 889 start-page: 45 year: 1999 end-page: 51 ident: CR25 article-title: Oncogenic activating mutations in the neu/erbB-2 oncogene are involved in the induction of mammary tumors publication-title: Ann N Y Acad Sci – volume: 13 start-page: 4131 year: 2007 end-page: 4135 ident: CR214 article-title: Molecular mechanisms of paclitaxel and NM-3 on human gastric cancer in a severe combined immune deficiency mice orthotopic implantation model publication-title: World J Gastroenterol – volume: 44 start-page: 602 year: 2006 end-page: 611 ident: CR76 article-title: Hypercholesterolemia in rats with hepatomas: increased oxysterols accelerate efflux but do not inhibit biosynthesis of cholesterol publication-title: Hepatology – volume: 39 start-page: 24 year: 2000 end-page: 27 ident: CR191 article-title: A technique for restraining rodents during hindlimb interventions publication-title: Contemp Top Lab Anim Sci – volume: 12 start-page: 954 year: 1992 end-page: 961 ident: CR67 article-title: Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease publication-title: Mol Cell Biol – volume: 77 start-page: 128 year: 2006 end-page: 133 ident: CR104 article-title: Establishment of a nude mice model of human monocytic leukemia with CNS and multiorgan extramedullary infiltration publication-title: Eur J Haematol – volume: 11 start-page: 7023 year: 2005 end-page: 7032 ident: CR9 article-title: Pharmacokinetic–pharmacodynamic relationships for the heat shock protein 90 molecular chaperone inhibitor 17-allylamino, 17-demethoxygeldanamycin in human ovarian cancer xenograft models publication-title: Clin Cancer Res – volume: 4 start-page: 245 year: 2001 end-page: 263 ident: CR113 article-title: high throughput screening of compounds for favorable metabolic properties in drug discovery publication-title: Comb Chem High Throughput Screen – volume: 1 start-page: 50 year: 1999 end-page: 62 ident: CR22 article-title: selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice publication-title: Neoplasia – volume: 97 start-page: 355 year: 2006 end-page: 361 ident: CR179 article-title: Mouse models of gastrointestinal tumors publication-title: Cancer Sci – volume: 111 start-page: 323 year: 2005 end-page: 334 ident: CR107 article-title: Preclinical testing of antileukemic drugs using an model of systemic disease publication-title: Methods Mol Med – volume: 29 start-page: 418 year: 2001 end-page: 425 ident: CR88 article-title: Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer publication-title: Nat Genet – volume: 278 start-page: 120 year: 1997 end-page: 123 ident: CR167 article-title: Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene publication-title: Science – volume: 14 start-page: 349 year: 1994 end-page: 361 ident: CR158 article-title: Murine models of liver metastasis publication-title: Invasion Metastasis – volume: 122 start-page: 1 year: 2008 end-page: 4 ident: CR100 article-title: Persistent use of ‘false’ cell lines publication-title: Int J Cancer – volume: 22 start-page: 549 year: 2005 end-page: 558 ident: CR153 article-title: Effect of asymptomatic natural infections due to common mouse pathogens on the metastatic progression of B16 murine melanoma in C57BL/6 mice publication-title: Clin Exp Metastasis – volume: 5 start-page: 741 year: 2006 end-page: 754 ident: CR166 article-title: The mighty mouse: genetically engineered mouse models in cancer drug development publication-title: Nat Rev Drug Discov – volume: 449 start-page: 557 year: 2007 end-page: 563 ident: CR89 article-title: Mesenchymal stem cells within tumour stroma promote breast cancer metastasis publication-title: Nature – volume: 106 start-page: 16375 year: 2009 end-page: 16380 ident: CR125 article-title: Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide publication-title: Proc Natl Acad Sci USA – volume: 26 start-page: 109 year: 2000 end-page: 113 ident: CR148 article-title: Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects publication-title: Nat Genet – volume: 5 start-page: 539 year: 2004 end-page: 551 ident: CR26 article-title: Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma publication-title: Cancer Cell – volume: 101 start-page: 121 year: 2008 end-page: 124 ident: CR53 article-title: Analgesia from a veterinary perspective publication-title: Br J Anaesth – volume: 9 start-page: 257 year: 2010 end-page: 267 ident: CR132 article-title: Integrative analysis of proteomic signatures, mutations, drug responsiveness in the NCI 60 cancer cell line set publication-title: Mol Cancer Ther – volume: 4 start-page: e4992 year: 2009 ident: CR174 article-title: Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression publication-title: PLoS One – volume: 5 start-page: 796 year: 2005 end-page: 806 ident: CR78 article-title: The multiple uses of fluorescent proteins to visualize cancer publication-title: Nat Rev Cancer – volume: 121 start-page: 335 year: 2005 end-page: 348 ident: CR129 article-title: Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion publication-title: Cell – volume: 3 start-page: 565 year: 1999 end-page: 577 ident: CR137 article-title: Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion publication-title: Mol Cell – volume: 69 start-page: 8256 year: 2009 end-page: 8264 ident: CR143 article-title: Activation of the Pl3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models publication-title: Cancer Res – volume: 559 start-page: 37 year: 2006 end-page: 44 ident: CR193 article-title: High-throughput pharmacokinetic method: cassette dosing in mice associated with minuscule serial bleedings and LC/MS/MS analysis publication-title: Anal Chim Acta – volume: 8 start-page: 359 year: 2008 end-page: 362 ident: CR204 article-title: Targeted therapeutics for cancer treatment: major progress towards personalised molecular medicine publication-title: Curr Opin Pharmacol – volume: 79 start-page: 8312 year: 2007 end-page: 8315 ident: CR44 article-title: A system for LogD screening of 96-well plates using a water-plug aspiration/injection method combined with high-performance liquid chromatography-mass spectrometry publication-title: Anal Chem – volume: 22 start-page: 473 year: 1992 end-page: 476 ident: CR201 article-title: The response of spontaneous and transplantable murine tumors to vasoactive agents measured by 31P magnetic resonance spectroscopy publication-title: Int J Radiat Oncol Biol Phys – volume: 7 start-page: 141 year: 2000 end-page: 144 ident: CR57 article-title: Monitoring specific T-cell responses to melanoma vaccines: ELISPOT, tetramers, and beyond publication-title: Clin Diagn Lab Immunol – volume: 17 start-page: 739 year: 2006 end-page: 741 ident: CR39 article-title: Cancer: off by a whisker publication-title: Nature – volume: 92 start-page: 97 year: 2006 end-page: 104 ident: CR37 article-title: Initial studies on an action spectrum for melanoma induction publication-title: Prog Biophys Mol Biol – volume: 7 start-page: 645 year: 2007 end-page: 658 ident: CR56 article-title: Maximizing mouse cancer models publication-title: Nat Rev Cancer – volume: 19 start-page: 1192 year: 2004 end-page: 1198 ident: CR213 article-title: Development of gastric adenocarcinoma in Mongolian gerbils after long-term infection with publication-title: J Gastroenterol Hepatol – year: 2002 ident: CR50 publication-title: The design of Animal Experiments: Reducing the Use of Animals in Research Through Better Experimental Design – volume: 452 start-page: 580 year: 2008 end-page: 589 ident: CR197 article-title: Imaging in the era of molecular oncology publication-title: Nature – volume: 15 start-page: 1133 year: 2003 end-page: 1143 ident: CR121 article-title: Adaptation to stress induced by restraining rats and mice in nose-only inhalation holders publication-title: Inhal Toxicol – volume: 143 start-page: 1055 year: 1993 end-page: 1062 ident: CR102 article-title: Dorsal skinfold chamber technique for intravital microscopy in nude mice publication-title: Am J Pathol – volume: 64 start-page: 5624 year: 2004 end-page: 5631 ident: CR72 article-title: The biological and therapeutic importance of gastrin gene expression in pancreatic adenocarcinomas publication-title: Cancer Res – volume: 432 start-page: 294 year: 2004 end-page: 297 ident: CR163 article-title: Targeted cancer therapy publication-title: Nature – volume: 20 start-page: 1801 year: 1999 end-page: 1808 ident: CR27 article-title: An esophagogastroduodenal anastomosis model for esophageal adenocarcinogenesis in rats and enhancement by iron overload publication-title: Carcinogenesis – volume: 14 start-page: 4572 year: 2008 end-page: 4583 ident: CR123 article-title: Molecular characterization of the pediatric preclinical testing panel publication-title: Clin Cancer Res – volume: 148 start-page: 154 year: 2005 end-page: 160 ident: CR95 article-title: Procedure for minimizing stress for fMRI studies in conscious rats publication-title: J Neurosci Methods – volume: 35 start-page: 1286 year: 1999 end-page: 1291 ident: CR194 article-title: Antibodies raised by gastrimmune inhibit the spontaneous metastasis of a human colorectal tumour, AP5LV publication-title: Eur J Cancer – ident: CR156 – volume: 97 start-page: 416 year: 2002 end-page: 424 ident: CR134 article-title: Hyaluronidase gene profiling and role of hyal-1 overexpression in an orthotopic model of prostate cancer publication-title: Int J Cancer – volume: 51 start-page: 43 year: 2003 end-page: 52 ident: CR169 article-title: Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) publication-title: Cancer Chemother Pharmacol – volume: 45 start-page: 812 year: 1999 end-page: 817 ident: CR195 article-title: A comparison of the therapeutic effectiveness of gastrin neutralisation in two human gastric cancer models: relation to endocrine and autocrine/paracrine gastrin mediated growth publication-title: Gut – volume: 9 start-page: 274 year: 2009 end-page: 284 ident: CR124 article-title: Metastasis: from dissemination to organ-specific colonization publication-title: Nat Rev Cancer – volume: 12 start-page: 391 year: 2003 end-page: 400 ident: CR36 article-title: Point: from animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system publication-title: Cancer Epidemiol Biomarkers Prev – volume: 2 start-page: 689 year: 2006 end-page: 700 ident: CR33 article-title: New approaches to molecular cancer therapeutics publication-title: Nat Chem Biol – volume: 13 start-page: 170 year: 2010 end-page: 187 ident: CR81 article-title: Plasma protein binding in drug discovery and development publication-title: Comb Chem High Throughput Screen – volume: 2 start-page: 53 year: 2001 end-page: 58 ident: CR68 article-title: Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis publication-title: J Vet Sci – volume: 35 start-page: 1 year: 2001 end-page: 41 ident: CR118 article-title: Refining procedures for the administration of substances. Report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. British Veterinary Association Animal Welfare Foundation/Fund for the Replacement of Animals in Medical Experiments/Royal Society for the Prevention of Cruelty to Animals/Universities Federation for Animal Welfare publication-title: Lab Anim – volume: 91 start-page: 176 year: 2006 end-page: 183 ident: CR64 article-title: The role of complement in the therapeutic activity of rituximab in a murine B lymphoma model homing in lymph nodes publication-title: Haematologica – volume: 82 start-page: 1049 year: 1968 end-page: 1052 ident: CR90 article-title: Effect of clomiphene on the uptake of estradiol by the anterior hypothalamus and hypophysis publication-title: Endocrinology – volume: 98 start-page: 8012 year: 2001 end-page: 8017 ident: CR114 article-title: Short tandem repeat profiling provides an international reference standard for human cell lines publication-title: Proc Natl Acad Sci USA – volume: Appendix 3 start-page: Appendix 3C year: 2008 ident: CR71 article-title: Diagnosis and treatment of mycoplasma-contaminated cell cultures publication-title: Curr Protoc Cytom – volume: 11 start-page: 3335 year: 2005 end-page: 3338 ident: CR69 article-title: Nude mice multi-drug resistance model of orthotopic transplantation of liver neoplasm and Tc-99m MIBI SPECT on p-glycoprotein publication-title: World J Gastroenterol – volume: 88 start-page: 2995 year: 2000 end-page: 3001 ident: CR212 article-title: Establishment of human prostate carcinoma skeletal metastasis models publication-title: Cancer – volume: 30 start-page: 89 year: 2002 end-page: 96 ident: CR142 article-title: Nonmyeloablative allogeneic bone marrow transplantation as immunotherapy for hematologic malignancies and metastatic solid tumors in preclinical models publication-title: Exp Hematol – volume: 15 start-page: 65 year: 2008 end-page: 79 ident: CR149 article-title: Estimation of apparent tumor vascular permeability from multiphoton fluorescence microscopic images of P22 rat sarcomas publication-title: Microcirculation – volume: 53 start-page: 946 year: 2004 end-page: 954 ident: CR4 article-title: Both soluble and membrane-bound forms of Flt3 ligand enhance tumor immunity following ‘suicide’ gene therapy in a murine colon carcinoma model publication-title: Cancer Immunol Immunother – volume: 4 start-page: 498 year: 2007 end-page: 512 ident: CR101 article-title: prediction of ionization constants of drugs publication-title: Mol Pharm – year: 1959 ident: CR160 publication-title: The Principles of Humane Experimental Technique – volume: 19 start-page: 43 year: 2006 end-page: 48 ident: CR210 article-title: Essential role for gene profiling analysis in the authentication of human cell lines publication-title: Hum Cell – volume: 52 start-page: 5395 year: 1992 end-page: 5399 ident: CR119 article-title: A synthetic antagonist to laminin inhibits the formation of osteolytic metastases by human melanoma cells in nude mice publication-title: Cancer Res – volume: 11 start-page: 7104s year: 2005 end-page: 7108s ident: CR111 article-title: Determining maximal tolerable dose of the monoclonal antibody BR96 labeled with 90Y or 177Lu in rats: establishment of a syngeneic tumor model to evaluate means to improve radioimmunotherapy publication-title: Clin Cancer Res – volume: 66 start-page: 3355 year: 2006 end-page: 3359 ident: CR13 article-title: Genetically engineered models have advantages over xenografts for preclinical studies publication-title: Cancer Res – volume: 24 start-page: 109 year: 2005 end-page: 119 ident: CR180 article-title: Repeated-measures models with constrained parameters for incomplete data in tumour xenograft experiments publication-title: Stat Med – volume: 98 start-page: 1176 year: 2006 end-page: 1178 ident: CR59 article-title: Realistic rodents? Debate grows over new mouse models of cancer publication-title: J Natl Cancer Inst – volume: 46 start-page: 27 year: 2001 end-page: 43 ident: CR6 article-title: Caco-2 monolayers in experimental and theoretical predictions of drug transport publication-title: Adv Drug Deliv Rev – volume: 209 start-page: 178 year: 1997 end-page: 185 ident: CR7 article-title: Good engraftment of B-cell precursor ALL in NOD-SCID mice publication-title: Klin Padiatr – volume: 42 start-page: 63 year: 2006 end-page: 69 ident: CR84 article-title: Rapid detection of mycoplasma contamination in cell cultures using SYBR Green-based real-time polymerase chain reaction publication-title: In Vitro Cell Dev Biol Anim – volume: 64 start-page: 6537 year: 2004 end-page: 6541 ident: CR82 article-title: Microregional effects of gemcitabine in HCT-116 xenografts publication-title: Cancer Res – volume: 4 start-page: 199 year: 1999 end-page: 207 ident: CR49 article-title: Reversible tumorigenesis by MYC in hematopoietic lineages publication-title: Mol Cell – volume: 43 start-page: 100 year: 2002 end-page: 109 ident: CR40 article-title: Welfare issues of genetically modified animals publication-title: Ilar J – volume: 11 start-page: 51 year: 2008 end-page: 60 ident: CR154 article-title: Modeling therapy resistance in genetically engineered mouse cancer models publication-title: Drug Resist Updat – volume: 8 start-page: 94 year: 2008 end-page: 107 ident: CR19 article-title: New approaches for imaging tumour responses to treatment publication-title: Nat Rev Cancer – volume: 29 start-page: 4389 year: 2009 end-page: 4395 ident: CR168 article-title: An immunocompetent murine model of metastatic mammary cancer accessible to bioluminescence imaging publication-title: Anticancer Res – volume: 63 start-page: 4239 year: 2003 end-page: 4243 ident: CR63 article-title: Viable circulating metastatic cells produced in orthotopic but not ectopic prostate cancer models publication-title: Cancer Res – volume: 413 start-page: 83 year: 2001 end-page: 86 ident: CR99 article-title: Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice publication-title: Nature – volume: 23 start-page: 790 year: 2005 ident: CR79 article-title: Dual-color, whole-body imaging in mice publication-title: Nat Biotechnol – volume: 16 start-page: 6611 year: 2008 end-page: 6616 ident: CR31 article-title: High throughput solubility determination with application to selection of compounds for fragment screening publication-title: Bioorg Med Chem – volume: 24 start-page: 472 year: 2001 end-page: 481 ident: CR103 article-title: Immune response against 3LL Lewis lung carcinoma potentiates the therapeutic efficacy of endostatin publication-title: J Immunother – volume: 23 start-page: 367 year: 2007 end-page: 372 ident: CR122 article-title: Eradication of cross-contaminated cell lines: a call for action publication-title: Cell Biol Toxicol – volume: 49 start-page: 3948 year: 2006 end-page: 3954 ident: CR131 article-title: Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability publication-title: J Med Chem – volume: 30 start-page: 2100 year: 2009 end-page: 2108 ident: CR86 article-title: MK2 regulates the early stages of skin tumor promotion publication-title: Carcinogenesis – volume: 24 start-page: 1887 year: 2003 end-page: 1896 ident: CR112 article-title: Spontaneous ECL cell carcinomas in cotton rats: natural course and prevention by a gastrin receptor antagonist publication-title: Carcinogenesis – volume: 406 start-page: 641 year: 2000 end-page: 645 ident: CR5 article-title: Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice publication-title: Nature – volume: 9 start-page: 55 year: 2009 end-page: 59 ident: CR130 article-title: Journal editorial policies, animal welfare, and the 3Rs publication-title: Am J Bioeth – volume: 23 start-page: 2662 year: 2009 end-page: 2672 ident: CR164 article-title: Multimodality imaging of TGFbeta signaling in breast cancer metastases publication-title: FASEB J – volume: 64 start-page: 8651 year: 2004 end-page: 8656 ident: CR208 article-title: Transgenic nude mouse with ubiquitous green fluorescent protein expression as a host for human tumors publication-title: Cancer Res – volume: 172 start-page: 209 year: 1994 end-page: 217 ident: CR11 article-title: Use of hu-IgG-SCID mice to evaluate the stability of human monoclonal IgG antibodies publication-title: J Immunol Methods – volume: 73 start-page: 29 year: 2005 end-page: 36 ident: CR65 article-title: Tumor infiltration by myeloid suppressor cells in response to T cell activation in rat gliomas publication-title: J Neurooncol – volume: 103 start-page: 3905 year: 2004 end-page: 3914 ident: CR105 article-title: Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies publication-title: Blood – volume: 100 start-page: 57 year: 2000 end-page: 70 ident: CR70 article-title: The hallmarks of cancer publication-title: Cell – volume: 93 start-page: 412 year: 1996 end-page: 420 ident: CR62 article-title: Graft-versus-leukaemia activity can be predicted by natural cytotoxicity against leukaemia cells publication-title: Br J Haematol – volume: 33 start-page: 119 year: 2005 end-page: 127 ident: CR150 article-title: Anaesthesia and post-operative analgesia following experimental surgery in laboratory rodents: are we making progress? publication-title: Altern Lab Anim – volume: 61 start-page: 6297 year: 2001 end-page: 6302 ident: CR209 article-title: p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac and publication-title: Cancer Res – volume: 28 start-page: 4009 year: 2009 end-page: 4021 ident: CR182 article-title: Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death publication-title: Oncogene – volume: 108 start-page: 304 year: 2008 end-page: 310 ident: CR146 article-title: A novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells. Laboratory investigation publication-title: J Neurosurg – volume: 10 start-page: 229 year: 1999 end-page: 233 ident: CR120 article-title: Inhibitory effect of ND2001 on spontaneous multiple metastasis of NC 65 tumors derived from human renal cancer cells intradermally transplanted into nude mice publication-title: Anticancer Drugs – volume: 49 start-page: 319 year: 1999 end-page: 323 ident: CR185 article-title: Body condition scoring: a rapid and accurate method for assessing health status in mice publication-title: Lab Anim Sci – volume: 112 start-page: 581 year: 1987 end-page: 591 ident: CR41 article-title: Temporal effects of 5.0 Gy radiation in healing subcutaneous microvasculature of a dorsal flap window chamber publication-title: Radiat Res – volume: 14 start-page: 1617 year: 2000 end-page: 1630 ident: CR60 article-title: Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2 publication-title: Genes Dev – volume: 410 start-page: 1111 year: 2001 end-page: 1116 ident: CR87 article-title: Somatic activation of the K-ras oncogene causes early onset lung cancer in mice publication-title: Nature – volume: 3 start-page: 921 year: 2003 end-page: 930 ident: CR35 article-title: Intravital imaging of cell movement in tumours publication-title: Nat Rev Cancer – volume: 21 start-page: 198 year: 2006 end-page: 201 ident: CR74 article-title: Carcinogenesis related to intense pulsed light and UV exposure: an experimental animal study publication-title: Lasers Med Sci – volume: 16 start-page: 626 year: 2008 end-page: 637 ident: CR211 article-title: Imaging of 186Re-liposome therapy in ovarian cancer xenograft model of peritoneal carcinomatosis publication-title: J Drug Target – volume: 98 start-page: 809 year: 2008 end-page: 815 ident: CR17 article-title: Interactions between microenvironment and cancer cells in two animal models of bone metastasis publication-title: Br J Cancer – volume: 870 start-page: 32 year: 2008 end-page: 37 ident: CR10 article-title: Application of dried blood spots combined with HPLC–MS/MS for the quantification of acetaminophen in toxicokinetic studies publication-title: J Chromatogr B Analyt Technol Biomed Life Sci – volume: 16 start-page: 2985 year: 1997 end-page: 2995 ident: CR196 article-title: Targeted expression of MYCN causes neuroblastoma in transgenic mice publication-title: EMBO J – volume: 85 start-page: 217 year: 2009 end-page: 221 ident: CR157 article-title: Direct xenograft tumor model for predicting chemotherapeutic drug response in cancer patients publication-title: Clin Pharmacol Ther – volume: 13 start-page: 4201 year: 2007 end-page: 4208 ident: CR189 article-title: Vascular endothelial growth factor trap blocks tumor growth, metastasis formation, and vascular leakage in an orthotopic murine renal cell cancer model publication-title: Clin Cancer Res – volume: 43 start-page: 191 year: 2002 end-page: 193 ident: CR51 article-title: The design and statistical analysis of animal experiments publication-title: ILAR J – volume: 24 start-page: 879 year: 2009 end-page: 891 ident: CR145 article-title: Immunohistopathological and neuroimaging characterization of murine orthotopic xenograft models of glioblastoma multiforme recapitulating the most salient features of human disease publication-title: Histol Histopathol – volume: 20 start-page: 1496 year: 2006 end-page: 1510 ident: CR140 article-title: Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to downregulation of the receptors publication-title: Genes Dev – volume: 12 start-page: 403 year: 1998 end-page: 410 ident: CR73 article-title: Antagonistic effects of styrylpyrone derivative (SPD) on 7,12-dimethylbenzanthracene-induced rat mammary tumors publication-title: In Vivo – volume: 13 start-page: 337 year: 2008 end-page: 342 ident: CR200 article-title: Mouse modifier genes in mammary tumorigenesis and metastasis publication-title: J Mammary Gland Biol Neoplasia – volume: 26 start-page: 329 year: 2009 end-page: 344 ident: CR96 article-title: Intravital microscopy of tumor angiogenesis and regression in the dorsal skin fold chamber: mechanistic insights and preclinical testing of therapeutic strategies publication-title: Clin Exp Metastasis – volume: 29 start-page: 322 year: 2001 end-page: 329 ident: CR126 article-title: Monitoring of engraftment and progression of acute lymphoblastic leukemia in individual NOD/SCID mice publication-title: Exp Hematol – volume: 13 start-page: 2168 year: 2007 end-page: 2177 ident: CR188 article-title: Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models publication-title: Clin Cancer Res – volume: 136 start-page: 1514 year: 2009 end-page: 1525 ident: CR207 article-title: Molecular imaging of pancreatic cancer in an animal model using targeted multifunctional nanoparticles publication-title: Gastroenterology – volume: 77 start-page: 640 year: 1998 end-page: 644 ident: CR106 article-title: Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression publication-title: Int J Cancer – volume: 51 start-page: 67 year: 2005 end-page: 72 ident: CR97 article-title: Detection of cancer cells in the peripheral blood and lung of mice after transplantation of human adenoid cystic carcinoma publication-title: Kobe J Med Sci – volume: 37 start-page: 718 year: 2005 end-page: 726 ident: CR29 article-title: Temporal dissection of p53 function and publication-title: Nat Genet – volume: 40 start-page: 827 year: 2004 end-page: 836 ident: CR91 article-title: Of mice and men: values and liabilities of the athymic nude mouse model in anticancer drug development publication-title: Eur J Cancer – volume: 139 start-page: 2373 year: 2009 end-page: 2379 ident: CR94 article-title: Oral administration of 3,3′-diindolylmethane inhibits lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice publication-title: J Nutr – volume: 6 start-page: 428 year: 2007 end-page: 440 ident: CR172 article-title: The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery publication-title: Mol Cancer Ther – volume: 16 start-page: 1442 year: 2010 end-page: 1451 ident: CR45 article-title: Patient-derived first generation xenografts of non-small cell lung cancers: promising tools for predicting drug responses for personalized chemotherapy publication-title: Clin Cancer Res – volume: 42 start-page: 1172 year: 2007 end-page: 1179 ident: CR42 article-title: bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma publication-title: J Pediatr Surg – volume: 25 start-page: 821 year: 2004 end-page: 825 ident: CR77 article-title: Enhancement of development of azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice publication-title: Carcinogenesis – volume: 173 start-page: 10 year: 2010 end-page: 20 ident: CR85 article-title: Revisiting strain-related differences in radiation sensitivity of the mouse lung: recognizing and avoiding the confounding effects of pleural effusions publication-title: Radiat Res – volume: 18 start-page: 843 year: 1998 end-page: 848 ident: CR108 article-title: Adjuvant 131I-anti-CEA-antibody radioimmunotherapy inhibits the development of experimental colonic carcinoma liver metastases publication-title: Anticancer Res – volume: 69 start-page: 143 year: 2009 end-page: 150 ident: CR83 article-title: Mutations in the phosphatidylinositol-3-kinase pathway predict for antitumor activity of the inhibitor PX-866 whereas oncogenic Ras is a dominant predictor for resistance publication-title: Cancer Res – volume: 7 start-page: 165 year: 2006 end-page: 182 ident: CR170 article-title: Preclinical pharmacokinetics: an approach towards safer and efficacious drugs publication-title: Curr Drug Metab – volume: 5 start-page: 43 year: 1993 end-page: 60 ident: CR184 article-title: Laser light scattering in biomedical diagnostics and therapy publication-title: J Laser Appl – volume: 443 start-page: 214 year: 2006 end-page: 217 ident: CR30 article-title: The pathological response to DNA damage does not contribute to p53-mediated tumour suppression publication-title: Nature – volume: 43 start-page: 501 year: 2008 end-page: 512 ident: CR46 article-title: Computational aqueous solubility prediction for drug-like compounds in congeneric series publication-title: Eur J Med Chem – volume: 49 start-page: 465 year: 1987 end-page: 475 ident: CR171 article-title: Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes publication-title: Cell – volume: 61 start-page: 513 year: 2001 end-page: 516 ident: CR199 article-title: Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched publication-title: Cancer Res – volume: 29 start-page: 891 year: 1997 end-page: 922 ident: CR80 article-title: Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices publication-title: Drug Metab Rev – volume: 39 start-page: 45 year: 1996 end-page: 56 ident: CR54 article-title: Mammary tumors induced by polyomavirus publication-title: Breast Cancer Res Treat – volume: 458 start-page: 719 year: 2009 end-page: 724 ident: CR176 article-title: The cancer genome publication-title: Nature – volume: 98 start-page: 580 year: 2006 end-page: 598 ident: CR203 article-title: Minimally invasive pharmacokinetic and pharmacodynamic technologies in hypothesis-testing clinical trials of innovative therapies publication-title: J Natl Cancer Inst – volume: 10 start-page: 789 year: 2004 end-page: 799 ident: CR190 article-title: Cancer genes and the pathways they control publication-title: Nat Med – volume: 107 start-page: 1358 year: 2008 end-page: 1368 ident: CR141 article-title: The human brain endothelial cell line hCMEC/D3 as a human blood–brain barrier model for drug transport studies publication-title: J Neurochem – volume: 22 start-page: 37 year: 1999 end-page: 43 ident: CR206 article-title: Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation publication-title: Nat Genet – volume: 80 start-page: 175 year: 1999 end-page: 184 ident: CR93 article-title: Radioimmunotherapy of micrometastases in lung with vascular targeted 213Bi publication-title: Br J Cancer – volume: 43 start-page: S52 issue: Suppl year: 1999 end-page: S55 ident: CR117 article-title: Matrilysin as a target for chemotherapy for colon cancer: use of antisense oligonucleotides as antimetastatic agents publication-title: Cancer Chemother Pharmacol – volume: 66 start-page: 3351 year: 2006 end-page: 3354 ident: CR162 article-title: Contributions of human tumor xenografts to anticancer drug development 10.1158/0008-5472.CAN-05-3627 publication-title: Cancer Res – volume: 7 start-page: 469 year: 2005 end-page: 483 ident: CR75 article-title: Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice publication-title: Cancer Cell – volume: 38 start-page: 2128 year: 2002 end-page: 2136 ident: CR47 article-title: Advancing animal models of neoplasia through bioluminescence imaging publication-title: Eur J Cancer – volume: 98 start-page: 493 year: 2002 end-page: 497 ident: CR8 article-title: Effects of -acetylcysteine in an esophageal carcinogenesis model in rats treated with diethylnitrosamine and diethyldithiocarbamate publication-title: Int J Cancer – volume: 455 start-page: 679 year: 2008 end-page: 683 ident: CR173 article-title: Modelling Myc inhibition as a cancer therapy publication-title: Nature – volume: 55 start-page: 836 year: 1995 end-page: 839 ident: CR181 article-title: Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP-470 publication-title: Cancer Res – volume: 68 start-page: 909 year: 1993 end-page: 915 ident: CR127 article-title: Enhancement of tumorigenicity of human breast adenocarcinoma cells in nude mice by Matrigel and fibroblasts publication-title: Br J Cancer – volume: 38 start-page: 286 year: 2004 end-page: 296 ident: CR155 article-title: Behavioural assessment of the effects of tumour growth in rats and the influence of the analgesics carprofen and meloxicam publication-title: Lab Anim – volume: 41 start-page: 235 year: 1999 end-page: 246 ident: CR178 article-title: Relationship between drug delivery and the intra-arterial infusion rate of SarCNU in C6 rat brain tumor model publication-title: J Neurooncol – volume: 23 start-page: 661 year: 2009 end-page: 668 ident: CR34 article-title: A bioluminescent orthotopic mouse model of human osteosarcoma that allows sensitive and rapid evaluation of new therapeutic agents publication-title: In Vivo – volume: 44 start-page: 42 year: 2006 end-page: 49 ident: CR177 article-title: PCR-based detection of mycoplasma species publication-title: J Microbiol – volume: 77 start-page: 1 year: 1998 end-page: 10 ident: CR205 article-title: UKCCCR guidelines for the welfare of animals in experimental neoplasia (Second Edition) publication-title: Br J Cancer – volume: 41 start-page: 269 year: 1991 end-page: 273 ident: CR147 article-title: Time of death of CNS tumor-bearing rats can be reliably predicted by body weight-loss patterns publication-title: Lab Anim Sci – volume: 12 start-page: 1599 year: 1998 end-page: 1609 ident: CR152 article-title: p107 is a suppressor of retinoblastoma development in pRb-deficient mice publication-title: Genes Dev – volume: 63 start-page: 4952 year: 2003 end-page: 4959 ident: CR215 article-title: LABAZ1: a metastatic tumor model for renal cell carcinoma expressing the carbonic anhydrase type 9 tumor antigen publication-title: Cancer Res – volume: 40 start-page: 111 year: 2006 end-page: 114 ident: CR198 article-title: Assessing the welfare of genetically altered mice publication-title: Lab Anim – volume: 47 start-page: 8 year: 2008 end-page: 15 ident: CR1 article-title: Evaluation of saphenous venipuncture and modified tail-clip blood collection in mice publication-title: J Am Assoc Lab Anim Sci – volume: 90 start-page: 1207 year: 1999 end-page: 1211 ident: CR192 article-title: Gastric tumor induction by 1,2-dimethylhydrazine in Wistar rats with intestinal metaplasia caused by X-irradiation publication-title: Jpn J Cancer Res – volume: 30 start-page: 326 year: 2003 end-page: 332 ident: CR186 article-title: Imaging of murine brain tumors using a 1.5 Tesla clinical MRI system publication-title: Can J Neurol Sci – ident: CR12 – volume: 284 start-page: 808 year: 1999 end-page: 812 ident: CR15 article-title: Effects of angiogenesis inhibitors on multistage carcinogenesis in mice publication-title: Science – volume: 60 start-page: 3605 year: 2000 end-page: 3611 ident: CR175 article-title: High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/− mice publication-title: Cancer Res – volume: 45 start-page: 360 year: 2009 end-page: 369 ident: CR115 article-title: Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy publication-title: Neuroimage – volume: 3 start-page: 111 year: 2010 end-page: 119 ident: CR139 article-title: Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma publication-title: Dis Model Mech – volume: 28 start-page: 1896 year: 2007 end-page: 1901 ident: CR32 article-title: Vasoactive intestinal peptide enhances growth and angiogenesis of human experimental prostate cancer in a xenograft model publication-title: Peptides – volume: 23 start-page: 961 year: 2005 end-page: 966 ident: CR66 article-title: Changes in intratumor heterogeneity in blood perfusion in intradermal human melanoma xenografts during tumor growth assessed by DCE-MRI publication-title: Magn Reson Imaging – volume: 40 start-page: 821 year: 2004 end-page: 826 ident: CR38 article-title: The hollow fibre model in cancer drug screening: the NCI experience publication-title: Eur J Cancer – volume: 2007 start-page: 97939 year: 2007 ident: CR48 article-title: EGFR activation and ultraviolet light-induced skin carcinogenesis publication-title: J Biomed Biotechnol – volume: 3 start-page: 149 year: 2004 end-page: 158 ident: CR18 article-title: Small-animal X-ray dose from micro-CT publication-title: Mol Imaging – volume: 32 start-page: 432 year: 2002 end-page: 434 ident: CR133 article-title: Species identification and confirmation of human and animal cell lines: a PCR-based method publication-title: Biotechniques – volume: 43 start-page: 244 year: 2002 end-page: 258 ident: CR52 article-title: Guidelines for the design and statistical analysis of experiments using laboratory animals publication-title: ILAR J – volume: 21 start-page: 2831 year: 2003 end-page: 2842 ident: CR58 article-title: Combretastatin A4 phosphate has tumor antivascular activity in rat and man as demonstrated by dynamic magnetic resonance imaging publication-title: J Clin Oncol – volume: 83 start-page: 627 year: 1991 end-page: 632 ident: CR165 article-title: Successful radioimmunotherapy for lung metastasis of human colonic cancer in nude mice publication-title: J Natl Cancer Inst – volume: Chapter 20 start-page: Unit 20 9 1 year: 2008 end-page: Unit 20 9–10 ident: CR144 article-title: ErbB2 transgenic mice: a tool for investigation of the immune prevention and treatment of mammary carcinomas publication-title: Curr Protoc Immunol – volume: 23 start-page: 96 issue: Suppl year: 2006 end-page: 98 ident: CR183 article-title: Importance and effects of enrichment on physiology, behaviour and breeding performance in mice publication-title: Altex – volume: 9 start-page: S58 year: 1999 end-page: S65 ident: CR187 article-title: Mutations in cancer genes of UV-induced skin tumors of hairless mice publication-title: J Epidemiol – volume: 333 start-page: 241 year: 2005 end-page: 246 ident: CR3 article-title: Ultraviolet B exposure activates Stat3 signaling via phosphorylation at tyrosine705 in skin of SKH1 hairless mouse: a target for the management of skin cancer? publication-title: Biochem Biophys Res Commun – volume: 58 start-page: 621 year: 2006 end-page: 681 ident: CR28 article-title: Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies publication-title: Pharmacol Rev – volume: 46 start-page: 1379 year: 2006 end-page: 1387 ident: CR21 article-title: logD7.4 modeling using Bayesian Regularized Neural Networks. Assessment and correction of the errors of prediction publication-title: J Chem Inf Model – volume: 21 start-page: 15 year: 2001 end-page: 23 ident: CR43 article-title: A good practice guide to the administration of substances and removal of blood, including routes and volumes publication-title: J Appl Toxicol – volume: 3 start-page: 527 year: 2002 end-page: 550 ident: CR151 article-title: The influence of DMPK as an integrated partner in modern drug discovery publication-title: Curr Drug Metab – volume: 37 start-page: 227 year: 2009 end-page: 234 ident: CR136 article-title: Urinary retention and cystitis associated with subcutaneous estradiol pellets in female nude mice publication-title: Toxicol Pathol – volume: 57 start-page: 67 year: 2005 end-page: 75 ident: CR92 article-title: Effects of rapamycin in the Eker rat model of tuberous sclerosis complex publication-title: Pediatr Res – volume: 463 start-page: 893 year: 2010 end-page: 898 ident: CR16 article-title: Signatures of mutation and selection in the cancer genome publication-title: Nature – volume: 93 start-page: 2702 year: 1996 end-page: 2707 ident: CR14 article-title: Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins publication-title: Proc Natl Acad Sci USA – volume: 58 start-page: 109 year: 1988 end-page: 113 ident: CR202 article-title: UKCCCR guidelines for the welfare of animals in experimental neoplasia publication-title: Br J Cancer – volume: 27 start-page: S232 year: 1996 end-page: S235 ident: CR128 article-title: Effect of hydralazine in spontaneous tumours assessed by oxygen electrodes and 31P-magnetic resonance spectroscopy publication-title: Br J Cancer Suppl – volume: 9 start-page: 78 year: 2007 end-page: 82 ident: CR24 article-title: Small animal absorbed radiation dose from serial micro-computed tomography imaging publication-title: Mol Imaging Biol – volume: 98 start-page: 861 year: 2009 end-page: 893 ident: CR109 article-title: Calculation of molecular lipophilicity: state-of-the-art and comparison of log P methods on more than 96,000 compounds publication-title: J Pharm Sci – volume: 29 start-page: 269 year: 2004 end-page: 282 ident: CR61 article-title: Reconstructing immunity after allogeneic transplantation publication-title: Immunol Res – volume: 19 start-page: 207 year: 1991 end-page: 213 ident: CR159 article-title: Growth and metastasis of human bladder cancer xenografts in the bladder of nude rats. A model for intravesical radioimmunotherapy publication-title: Urol Res – volume: 50 start-page: 219 year: 1966 end-page: 244 ident: CR55 article-title: Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man publication-title: Cancer Chemother Rep – volume: 23 start-page: 877 year: 2009 end-page: 889 ident: CR216 article-title: Mouse models of human AML accurately predict chemotherapy response publication-title: Genes Dev – volume: 22 start-page: 305 year: 2003 end-page: 311 ident: CR98 article-title: chamber angiogenesis assay: an optimized Matrigel plug assay for fast assessment of antiangiogenic activity publication-title: Int J Oncol – volume: 17 start-page: 3112 year: 2003 end-page: 3126 ident: CR2 article-title: Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma publication-title: Genes Dev – volume: 68 start-page: 3827 year: 2008 end-page: 3834 ident: CR138 article-title: Imaging pharmacodynamics of the alpha-folate receptor-targeted thymidylate synthase inhibitor BGC 945 publication-title: Cancer Res – volume: 99 start-page: 15608 year: 2002 end-page: 15613 ident: CR135 article-title: Noninvasive imaging of protein–protein interactions in living subjects by using reporter protein complementation and reconstitution strategies publication-title: Proc Natl Acad Sci USA – volume: 7 start-page: 864 year: 2001 end-page: 868 ident: CR20 article-title: measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy publication-title: Nat Med – volume: 25 start-page: 4429 year: 2006 end-page: 4440 ident: CR116 article-title: Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model publication-title: Oncogene – volume: 2 start-page: 743 year: 2009 end-page: 750 ident: CR23 article-title: Flavones as colorectal cancer chemopreventive agents – phenol- -methylation enhances efficacy publication-title: Cancer Prev Res (Phila PA) – volume: 10 start-page: 59 year: 2010 end-page: 64 ident: CR161 article-title: A census of amplified and overexpressed human cancer genes publication-title: Nat Rev Cancer – volume: 6 start-page: 428 year: 2007 ident: BF6605642_CR172 publication-title: Mol Cancer Ther doi: 10.1158/1535-7163.MCT-06-0324 – volume: 458 start-page: 719 year: 2009 ident: BF6605642_CR176 publication-title: Nature doi: 10.1038/nature07943 – volume: 3 start-page: 149 year: 2004 ident: BF6605642_CR18 publication-title: Mol Imaging doi: 10.1162/1535350042380326 – volume: 98 start-page: 8012 year: 2001 ident: BF6605642_CR114 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.121616198 – volume: 98 start-page: 1176 year: 2006 ident: BF6605642_CR59 publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djj381 – volume: 12 start-page: 954 year: 1992 ident: BF6605642_CR67 publication-title: Mol Cell Biol doi: 10.1128/MCB.12.3.954 – volume: 93 start-page: 412 year: 1996 ident: BF6605642_CR62 publication-title: Br J Haematol doi: 10.1046/j.1365-2141.1996.4941035.x – volume: 99 start-page: 15608 year: 2002 ident: BF6605642_CR135 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.242594299 – volume: 30 start-page: 326 year: 2003 ident: BF6605642_CR186 publication-title: Can J Neurol Sci doi: 10.1017/S0317167100003036 – volume: 61 start-page: 513 year: 2001 ident: BF6605642_CR199 publication-title: Cancer Res – volume: 51 start-page: 67 year: 2005 ident: BF6605642_CR97 publication-title: Kobe J Med Sci – volume: 284 start-page: 808 year: 1999 ident: BF6605642_CR15 publication-title: Science doi: 10.1126/science.284.5415.808 – volume: 100 start-page: 57 year: 2000 ident: BF6605642_CR70 publication-title: Cell doi: 10.1016/S0092-8674(00)81683-9 – volume: 12 start-page: 1599 year: 1998 ident: BF6605642_CR152 publication-title: Genes Dev doi: 10.1101/gad.12.11.1599 – volume: 43 start-page: 501 year: 2008 ident: BF6605642_CR46 publication-title: Eur J Med Chem doi: 10.1016/j.ejmech.2007.04.009 – volume: 91 start-page: 176 year: 2006 ident: BF6605642_CR64 publication-title: Haematologica – volume: 107 start-page: 1358 year: 2008 ident: BF6605642_CR141 publication-title: J Neurochem doi: 10.1111/j.1471-4159.2008.05730.x – volume: 45 start-page: 812 year: 1999 ident: BF6605642_CR195 publication-title: Gut doi: 10.1136/gut.45.6.812 – volume: 35 start-page: 1286 year: 1999 ident: BF6605642_CR194 publication-title: Eur J Cancer doi: 10.1016/S0959-8049(99)00115-X – volume: 5 start-page: 539 year: 2004 ident: BF6605642_CR26 publication-title: Cancer Cell doi: 10.1016/j.ccr.2004.05.025 – volume: 22 start-page: 305 year: 2003 ident: BF6605642_CR98 publication-title: Int J Oncol – volume: 37 start-page: 718 year: 2005 ident: BF6605642_CR29 publication-title: Nat Genet doi: 10.1038/ng1572 – volume: 3 start-page: 527 year: 2002 ident: BF6605642_CR151 publication-title: Curr Drug Metab doi: 10.2174/1389200023337135 – volume: 61 start-page: 6297 year: 2001 ident: BF6605642_CR209 publication-title: Cancer Res – volume: 32 start-page: 432 year: 2002 ident: BF6605642_CR133 publication-title: Biotechniques doi: 10.2144/02322rr05 – volume: 5 start-page: 741 year: 2006 ident: BF6605642_CR166 publication-title: Nat Rev Drug Discov doi: 10.1038/nrd2110 – volume: 7 start-page: 469 year: 2005 ident: BF6605642_CR75 publication-title: Cancer Cell doi: 10.1016/j.ccr.2005.04.023 – volume: 148 start-page: 154 year: 2005 ident: BF6605642_CR95 publication-title: J Neurosci Methods doi: 10.1016/j.jneumeth.2005.04.011 – volume: 39 start-page: 45 year: 1996 ident: BF6605642_CR54 publication-title: Breast Cancer Res Treat doi: 10.1007/BF01806077 – volume: 5 start-page: 43 year: 1993 ident: BF6605642_CR184 publication-title: J Laser Appl doi: 10.2351/1.4745330 – volume-title: The Principles of Humane Experimental Technique year: 1959 ident: BF6605642_CR160 – volume: 47 start-page: 8 year: 2008 ident: BF6605642_CR1 publication-title: J Am Assoc Lab Anim Sci – volume: 16 start-page: 626 year: 2008 ident: BF6605642_CR211 publication-title: J Drug Target doi: 10.1080/10611860802230372 – volume: 14 start-page: 1617 year: 2000 ident: BF6605642_CR60 publication-title: Genes Dev doi: 10.1101/gad.14.13.1617 – volume: 13 start-page: 323 year: 2008 ident: BF6605642_CR110 publication-title: J Mammary Gland Biol Neoplasia doi: 10.1007/s10911-008-9087-3 – volume: 2007 start-page: 97939 year: 2007 ident: BF6605642_CR48 publication-title: J Biomed Biotechnol – volume: 13 start-page: 170 year: 2010 ident: BF6605642_CR81 publication-title: Comb Chem High Throughput Screen doi: 10.2174/138620710790596745 – volume: 42 start-page: 63 year: 2006 ident: BF6605642_CR84 publication-title: In Vitro Cell Dev Biol Anim doi: 10.1290/0505035.1 – volume: 64 start-page: 8651 year: 2004 ident: BF6605642_CR208 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-04-3118 – volume: 53 start-page: 946 year: 2004 ident: BF6605642_CR4 publication-title: Cancer Immunol Immunother doi: 10.1007/s00262-004-0553-5 – volume: 93 start-page: 2702 year: 1996 ident: BF6605642_CR14 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.93.7.2702 – volume: 2 start-page: 689 year: 2006 ident: BF6605642_CR33 publication-title: Nat Chem Biol doi: 10.1038/nchembio840 – volume: Appendix 3 start-page: Appendix 3C year: 2008 ident: BF6605642_CR71 publication-title: Curr Protoc Cytom – volume: 24 start-page: 109 year: 2005 ident: BF6605642_CR180 publication-title: Stat Med doi: 10.1002/sim.1775 – volume: 136 start-page: 1514 year: 2009 ident: BF6605642_CR207 publication-title: Gastroenterology doi: 10.1053/j.gastro.2009.01.006 – volume: 3 start-page: 111 year: 2010 ident: BF6605642_CR139 publication-title: Dis Model Mech doi: 10.1242/dmm.003681 – volume: 172 start-page: 209 year: 1994 ident: BF6605642_CR11 publication-title: J Immunol Methods doi: 10.1016/0022-1759(94)90108-2 – volume: 20 start-page: 1801 year: 1999 ident: BF6605642_CR27 publication-title: Carcinogenesis doi: 10.1093/carcin/20.9.1801 – volume: 889 start-page: 45 year: 1999 ident: BF6605642_CR25 publication-title: Ann N Y Acad Sci doi: 10.1111/j.1749-6632.1999.tb08722.x – volume: 410 start-page: 1111 year: 2001 ident: BF6605642_CR87 publication-title: Nature doi: 10.1038/35074129 – volume: 449 start-page: 557 year: 2007 ident: BF6605642_CR89 publication-title: Nature doi: 10.1038/nature06188 – volume: 27 start-page: S232 year: 1996 ident: BF6605642_CR128 publication-title: Br J Cancer Suppl – volume: 33 start-page: 119 year: 2005 ident: BF6605642_CR150 publication-title: Altern Lab Anim doi: 10.1177/026119290503300207 – volume: 13 start-page: 337 year: 2008 ident: BF6605642_CR200 publication-title: J Mammary Gland Biol Neoplasia doi: 10.1007/s10911-008-9089-1 – volume: 43 start-page: 244 year: 2002 ident: BF6605642_CR52 publication-title: ILAR J doi: 10.1093/ilar.43.4.244 – volume: 14 start-page: 4572 year: 2008 ident: BF6605642_CR123 publication-title: Clin Cancer Res doi: 10.1158/1078-0432.CCR-07-5090 – volume: 37 start-page: 227 year: 2009 ident: BF6605642_CR136 publication-title: Toxicol Pathol doi: 10.1177/0192623308329281 – volume: 55 start-page: 836 year: 1995 ident: BF6605642_CR181 publication-title: Cancer Res – volume: 38 start-page: 2128 year: 2002 ident: BF6605642_CR47 publication-title: Eur J Cancer doi: 10.1016/S0959-8049(02)00410-0 – volume: 73 start-page: 29 year: 2005 ident: BF6605642_CR65 publication-title: J Neurooncol doi: 10.1007/s11060-007-9442-z – volume: 29 start-page: 322 year: 2001 ident: BF6605642_CR126 publication-title: Exp Hematol doi: 10.1016/S0301-472X(00)00669-X – volume: 7 start-page: 141 year: 2000 ident: BF6605642_CR57 publication-title: Clin Diagn Lab Immunol doi: 10.1128/CDLI.7.2.141-144.2000 – volume: 46 start-page: 27 year: 2001 ident: BF6605642_CR6 publication-title: Adv Drug Deliv Rev doi: 10.1016/S0169-409X(00)00128-9 – volume: 60 start-page: 3605 year: 2000 ident: BF6605642_CR175 publication-title: Cancer Res – volume: 5 start-page: 796 year: 2005 ident: BF6605642_CR78 publication-title: Nat Rev Cancer doi: 10.1038/nrc1717 – volume: 69 start-page: 143 year: 2009 ident: BF6605642_CR83 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-07-6656 – volume: 4 start-page: 245 year: 2001 ident: BF6605642_CR113 publication-title: Comb Chem High Throughput Screen doi: 10.2174/1386207013331101 – volume: 43 start-page: 100 year: 2002 ident: BF6605642_CR40 publication-title: Ilar J doi: 10.1093/ilar.43.2.100 – volume: 66 start-page: 3355 year: 2006 ident: BF6605642_CR13 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-05-3827 – volume: 97 start-page: 416 year: 2002 ident: BF6605642_CR134 publication-title: Int J Cancer doi: 10.1002/ijc.1638 – ident: BF6605642_CR156 – volume: 85 start-page: 217 year: 2009 ident: BF6605642_CR157 publication-title: Clin Pharmacol Ther doi: 10.1038/clpt.2008.200 – volume: 23 start-page: 96 issue: Suppl year: 2006 ident: BF6605642_CR183 publication-title: Altex – volume: 11 start-page: 51 year: 2008 ident: BF6605642_CR154 publication-title: Drug Resist Updat doi: 10.1016/j.drup.2007.11.002 – volume: 7 start-page: 645 year: 2007 ident: BF6605642_CR56 publication-title: Nat Rev Cancer doi: 10.1038/nrc2192 – volume: 101 start-page: 121 year: 2008 ident: BF6605642_CR53 publication-title: Br J Anaesth doi: 10.1093/bja/aen087 – volume: 3 start-page: 921 year: 2003 ident: BF6605642_CR35 publication-title: Nat Rev Cancer doi: 10.1038/nrc1231 – volume: 21 start-page: 198 year: 2006 ident: BF6605642_CR74 publication-title: Lasers Med Sci doi: 10.1007/s10103-006-0395-9 – volume: 40 start-page: 821 year: 2004 ident: BF6605642_CR38 publication-title: Eur J Cancer doi: 10.1016/j.ejca.2003.11.029 – volume: 24 start-page: 472 year: 2001 ident: BF6605642_CR103 publication-title: J Immunother doi: 10.1097/00002371-200111000-00004 – volume: 92 start-page: 97 year: 2006 ident: BF6605642_CR37 publication-title: Prog Biophys Mol Biol doi: 10.1016/j.pbiomolbio.2006.02.024 – volume: 18 start-page: 843 year: 1998 ident: BF6605642_CR108 publication-title: Anticancer Res – volume: 24 start-page: 879 year: 2009 ident: BF6605642_CR145 publication-title: Histol Histopathol – volume: 77 start-page: 128 year: 2006 ident: BF6605642_CR104 publication-title: Eur J Haematol doi: 10.1111/j.1600-0609.2006.00686.x – volume: 22 start-page: 37 year: 1999 ident: BF6605642_CR206 publication-title: Nat Genet doi: 10.1038/8743 – volume: 19 start-page: 207 year: 1991 ident: BF6605642_CR159 publication-title: Urol Res doi: 10.1007/BF00305296 – volume: 870 start-page: 32 year: 2008 ident: BF6605642_CR10 publication-title: J Chromatogr B Analyt Technol Biomed Life Sci doi: 10.1016/j.jchromb.2008.05.025 – volume: 28 start-page: 1896 year: 2007 ident: BF6605642_CR32 publication-title: Peptides doi: 10.1016/j.peptides.2007.04.015 – volume: 22 start-page: 549 year: 2005 ident: BF6605642_CR153 publication-title: Clin Exp Metastasis doi: 10.1007/s10585-005-5261-9 – volume: 112 start-page: 581 year: 1987 ident: BF6605642_CR41 publication-title: Radiat Res doi: 10.2307/3577110 – volume: 7 start-page: 864 year: 2001 ident: BF6605642_CR20 publication-title: Nat Med doi: 10.1038/89997 – volume: 12 start-page: 403 year: 1998 ident: BF6605642_CR73 publication-title: In Vivo – volume: 44 start-page: 42 year: 2006 ident: BF6605642_CR177 publication-title: J Microbiol – volume: 2 start-page: 53 year: 2001 ident: BF6605642_CR68 publication-title: J Vet Sci doi: 10.4142/jvs.2001.2.1.53 – volume: 77 start-page: 1 year: 1998 ident: BF6605642_CR205 publication-title: Br J Cancer – volume: 13 start-page: 2168 year: 2007 ident: BF6605642_CR188 publication-title: Clin Cancer Res doi: 10.1158/1078-0432.CCR-06-0918 – volume: 173 start-page: 10 year: 2010 ident: BF6605642_CR85 publication-title: Radiat Res doi: 10.1667/RR1911.1 – volume: 97 start-page: 355 year: 2006 ident: BF6605642_CR179 publication-title: Cancer Sci doi: 10.1111/j.1349-7006.2006.00190.x – volume: 82 start-page: 1049 year: 1968 ident: BF6605642_CR90 publication-title: Endocrinology doi: 10.1210/endo-82-5-1049 – volume: 122 start-page: 1 year: 2008 ident: BF6605642_CR100 publication-title: Int J Cancer doi: 10.1002/ijc.23233 – volume: 559 start-page: 37 year: 2006 ident: BF6605642_CR193 publication-title: Anal Chim Acta doi: 10.1016/j.aca.2005.11.049 – volume: 63 start-page: 4952 year: 2003 ident: BF6605642_CR215 publication-title: Cancer Res – volume: 41 start-page: 235 year: 1999 ident: BF6605642_CR178 publication-title: J Neurooncol doi: 10.1023/A:1006104220315 – volume: 88 start-page: 2995 year: 2000 ident: BF6605642_CR212 publication-title: Cancer doi: 10.1002/1097-0142(20000615)88:12+<2995::AID-CNCR15>3.0.CO;2-Y – volume: 63 start-page: 4239 year: 2003 ident: BF6605642_CR63 publication-title: Cancer Res – volume: 413 start-page: 83 year: 2001 ident: BF6605642_CR99 publication-title: Nature doi: 10.1038/35092584 – volume: 11 start-page: 7104s year: 2005 ident: BF6605642_CR111 publication-title: Clin Cancer Res doi: 10.1158/1078-0432.CCR-1004-0004 – volume: 98 start-page: 809 year: 2008 ident: BF6605642_CR17 publication-title: Br J Cancer doi: 10.1038/sj.bjc.6604238 – volume: Chapter 20 start-page: Unit 20 9 1 year: 2008 ident: BF6605642_CR144 publication-title: Curr Protoc Immunol – volume: 57 start-page: 67 year: 2005 ident: BF6605642_CR92 publication-title: Pediatr Res doi: 10.1203/01.PDR.0000147727.78571.07 – volume: 1 start-page: 50 year: 1999 ident: BF6605642_CR22 publication-title: Neoplasia doi: 10.1038/sj.neo.7900005 – volume: 121 start-page: 335 year: 2005 ident: BF6605642_CR129 publication-title: Cell doi: 10.1016/j.cell.2005.02.034 – volume: 9 start-page: S58 year: 1999 ident: BF6605642_CR187 publication-title: J Epidemiol doi: 10.2188/jea.9.6sup_58 – volume: 13 start-page: 4131 year: 2007 ident: BF6605642_CR214 publication-title: World J Gastroenterol doi: 10.3748/wjg.v13.i30.4131 – volume: 64 start-page: 5624 year: 2004 ident: BF6605642_CR72 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-04-0106 – volume: 66 start-page: 3351 year: 2006 ident: BF6605642_CR162 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-05-3627 – volume: 17 start-page: 3112 year: 2003 ident: BF6605642_CR2 publication-title: Genes Dev doi: 10.1101/gad.1158703 – volume: 23 start-page: 367 year: 2007 ident: BF6605642_CR122 publication-title: Cell Biol Toxicol doi: 10.1007/s10565-007-9019-9 – volume: 2 start-page: 743 year: 2009 ident: BF6605642_CR23 publication-title: Cancer Prev Res (Phila PA) doi: 10.1158/1940-6207.CAPR-09-0081 – volume: 16 start-page: 2985 year: 1997 ident: BF6605642_CR196 publication-title: EMBO J doi: 10.1093/emboj/16.11.2985 – volume: 58 start-page: 109 year: 1988 ident: BF6605642_CR202 publication-title: Br J Cancer doi: 10.1038/bjc.1988.174 – volume: 24 start-page: 1887 year: 2003 ident: BF6605642_CR112 publication-title: Carcinogenesis doi: 10.1093/carcin/bgg156 – volume: 23 start-page: 2662 year: 2009 ident: BF6605642_CR164 publication-title: FASEB J doi: 10.1096/fj.08-126920 – volume: 49 start-page: 465 year: 1987 ident: BF6605642_CR171 publication-title: Cell doi: 10.1016/0092-8674(87)90449-1 – volume: 44 start-page: 602 year: 2006 ident: BF6605642_CR76 publication-title: Hepatology doi: 10.1002/hep.21291 – volume: 9 start-page: 78 year: 2007 ident: BF6605642_CR24 publication-title: Mol Imaging Biol doi: 10.1007/s11307-007-0080-9 – volume: 83 start-page: 627 year: 1991 ident: BF6605642_CR165 publication-title: J Natl Cancer Inst doi: 10.1093/jnci/83.9.627 – volume: 69 start-page: 8256 year: 2009 ident: BF6605642_CR143 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-09-1689 – volume: 17 start-page: 739 year: 2006 ident: BF6605642_CR39 publication-title: Nature doi: 10.1038/442739a – volume: 443 start-page: 214 year: 2006 ident: BF6605642_CR30 publication-title: Nature doi: 10.1038/nature05077 – volume: 68 start-page: 3827 year: 2008 ident: BF6605642_CR138 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-08-0135 – volume: 68 start-page: 909 year: 1993 ident: BF6605642_CR127 publication-title: Br J Cancer doi: 10.1038/bjc.1993.453 – volume: 13 start-page: 4201 year: 2007 ident: BF6605642_CR189 publication-title: Clin Cancer Res doi: 10.1158/1078-0432.CCR-06-2553 – volume: 80 start-page: 175 year: 1999 ident: BF6605642_CR93 publication-title: Br J Cancer doi: 10.1038/sj.bjc.6690337 – volume: 19 start-page: 1192 year: 2004 ident: BF6605642_CR213 publication-title: J Gastroenterol Hepatol doi: 10.1111/j.1440-1746.2004.03469.x – volume: 50 start-page: 219 year: 1966 ident: BF6605642_CR55 publication-title: Cancer Chemother Rep – volume: 42 start-page: 1172 year: 2007 ident: BF6605642_CR42 publication-title: J Pediatr Surg doi: 10.1016/j.jpedsurg.2007.02.027 – volume: 3 start-page: 565 year: 1999 ident: BF6605642_CR137 publication-title: Mol Cell doi: 10.1016/S1097-2765(00)80350-0 – volume: 23 start-page: 790 year: 2005 ident: BF6605642_CR79 publication-title: Nat Biotechnol doi: 10.1038/nbt0705-790 – volume: 29 start-page: 4389 year: 2009 ident: BF6605642_CR168 publication-title: Anticancer Res – volume: 98 start-page: 861 year: 2009 ident: BF6605642_CR109 publication-title: J Pharm Sci doi: 10.1002/jps.21494 – volume: 333 start-page: 241 year: 2005 ident: BF6605642_CR3 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2005.05.106 – volume: 12 start-page: 391 year: 2003 ident: BF6605642_CR36 publication-title: Cancer Epidemiol Biomarkers Prev – volume: 30 start-page: 89 year: 2002 ident: BF6605642_CR142 publication-title: Exp Hematol doi: 10.1016/S0301-472X(01)00759-7 – volume: 4 start-page: 498 year: 2007 ident: BF6605642_CR101 publication-title: Mol Pharm doi: 10.1021/mp070019+ – volume: 15 start-page: 1133 year: 2003 ident: BF6605642_CR121 publication-title: Inhal Toxicol doi: 10.1080/08958370390228592 – volume: 26 start-page: 329 year: 2009 ident: BF6605642_CR96 publication-title: Clin Exp Metastasis doi: 10.1007/s10585-008-9234-7 – volume: 25 start-page: 4429 year: 2006 ident: BF6605642_CR116 publication-title: Oncogene doi: 10.1038/sj.onc.1209482 – volume: 43 start-page: S52 issue: Suppl year: 1999 ident: BF6605642_CR117 publication-title: Cancer Chemother Pharmacol doi: 10.1007/s002800051098 – volume: 25 start-page: 821 year: 2004 ident: BF6605642_CR77 publication-title: Carcinogenesis doi: 10.1093/carcin/bgh059 – volume: 45 start-page: 360 year: 2009 ident: BF6605642_CR115 publication-title: Neuroimage doi: 10.1016/j.neuroimage.2008.12.022 – volume: 4 start-page: 199 year: 1999 ident: BF6605642_CR49 publication-title: Mol Cell doi: 10.1016/S1097-2765(00)80367-6 – volume: 15 start-page: 65 year: 2008 ident: BF6605642_CR149 publication-title: Microcirculation doi: 10.1080/10739680701436350 – volume: 43 start-page: 191 year: 2002 ident: BF6605642_CR51 publication-title: ILAR J doi: 10.1093/ilar.43.4.191 – volume: 8 start-page: 94 year: 2008 ident: BF6605642_CR19 publication-title: Nat Rev Cancer doi: 10.1038/nrc2289 – volume: 40 start-page: 827 year: 2004 ident: BF6605642_CR91 publication-title: Eur J Cancer doi: 10.1016/j.ejca.2003.11.028 – volume: 452 start-page: 580 year: 2008 ident: BF6605642_CR197 publication-title: Nature doi: 10.1038/nature06917 – volume: 11 start-page: 3335 year: 2005 ident: BF6605642_CR69 publication-title: World J Gastroenterol doi: 10.3748/wjg.v11.i22.3335 – volume: 16 start-page: 1442 year: 2010 ident: BF6605642_CR45 publication-title: Clin Cancer Res doi: 10.1158/1078-0432.CCR-09-2878 – volume: 21 start-page: 2831 year: 2003 ident: BF6605642_CR58 publication-title: J Clin Oncol doi: 10.1200/JCO.2003.05.187 – volume: 98 start-page: 580 year: 2006 ident: BF6605642_CR203 publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djj162 – volume: 29 start-page: 891 year: 1997 ident: BF6605642_CR80 publication-title: Drug Metab Rev doi: 10.3109/03602539709002237 – volume: 432 start-page: 294 year: 2004 ident: BF6605642_CR163 publication-title: Nature doi: 10.1038/nature03095 – volume: 23 start-page: 877 year: 2009 ident: BF6605642_CR216 publication-title: Genes Dev doi: 10.1101/gad.1771409 – volume: 46 start-page: 1379 year: 2006 ident: BF6605642_CR21 publication-title: J Chem Inf Model doi: 10.1021/ci0504014 – volume: 26 start-page: 109 year: 2000 ident: BF6605642_CR148 publication-title: Nat Genet doi: 10.1038/79075 – volume: 64 start-page: 6537 year: 2004 ident: BF6605642_CR82 publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-04-0986 – volume: 106 start-page: 16375 year: 2009 ident: BF6605642_CR125 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0901310106 – volume: 20 start-page: 1496 year: 2006 ident: BF6605642_CR140 publication-title: Genes Dev doi: 10.1101/gad.1417406 – volume: 139 start-page: 2373 year: 2009 ident: BF6605642_CR94 publication-title: J Nutr doi: 10.3945/jn.109.111864 – volume: 98 start-page: 493 year: 2002 ident: BF6605642_CR8 publication-title: Int J Cancer doi: 10.1002/ijc.10215 – volume: 49 start-page: 319 year: 1999 ident: BF6605642_CR185 publication-title: Lab Anim Sci – volume: 108 start-page: 304 year: 2008 ident: BF6605642_CR146 publication-title: J Neurosurg doi: 10.3171/JNS/2008/108/2/0304 – volume: 14 start-page: 349 year: 1994 ident: BF6605642_CR158 publication-title: Invasion Metastasis – volume: 49 start-page: 3948 year: 2006 ident: BF6605642_CR131 publication-title: J Med Chem doi: 10.1021/jm060230+ – volume: 28 start-page: 4009 year: 2009 ident: BF6605642_CR182 publication-title: Oncogene doi: 10.1038/onc.2009.250 – volume: 463 start-page: 893 year: 2010 ident: BF6605642_CR16 publication-title: Nature doi: 10.1038/nature08768 – volume: 111 start-page: 323 year: 2005 ident: BF6605642_CR107 publication-title: Methods Mol Med – volume: 278 start-page: 120 year: 1997 ident: BF6605642_CR167 publication-title: Science doi: 10.1126/science.278.5335.120 – volume: 23 start-page: 961 year: 2005 ident: BF6605642_CR66 publication-title: Magn Reson Imaging doi: 10.1016/j.mri.2005.09.006 – volume: 19 start-page: 43 year: 2006 ident: BF6605642_CR210 publication-title: Hum Cell doi: 10.1111/j.1749-0774.2005.00007.x – volume: 79 start-page: 8312 year: 2007 ident: BF6605642_CR44 publication-title: Anal Chem doi: 10.1021/ac0709798 – volume: 90 start-page: 1207 year: 1999 ident: BF6605642_CR192 publication-title: Jpn J Cancer Res doi: 10.1111/j.1349-7006.1999.tb00697.x – volume: 455 start-page: 679 year: 2008 ident: BF6605642_CR173 publication-title: Nature doi: 10.1038/nature07260 – volume: 41 start-page: 269 year: 1991 ident: BF6605642_CR147 publication-title: Lab Anim Sci – volume: 51 start-page: 43 year: 2003 ident: BF6605642_CR169 publication-title: Cancer Chemother Pharmacol doi: 10.1007/s00280-002-0529-0 – volume: 30 start-page: 2100 year: 2009 ident: BF6605642_CR86 publication-title: Carcinogenesis doi: 10.1093/carcin/bgp238 – volume: 7 start-page: 165 year: 2006 ident: BF6605642_CR170 publication-title: Curr Drug Metab doi: 10.2174/138920006775541552 – ident: BF6605642_CR12 – volume: 23 start-page: 661 year: 2009 ident: BF6605642_CR34 publication-title: In Vivo – volume: 406 start-page: 641 year: 2000 ident: BF6605642_CR5 publication-title: Nature doi: 10.1038/35020592 – volume-title: The design of Animal Experiments: Reducing the Use of Animals in Research Through Better Experimental Design year: 2002 ident: BF6605642_CR50 – volume: 103 start-page: 3905 year: 2004 ident: BF6605642_CR105 publication-title: Blood doi: 10.1182/blood-2003-08-2911 – volume: 10 start-page: 229 year: 1999 ident: BF6605642_CR120 publication-title: Anticancer Drugs doi: 10.1097/00001813-199902000-00012 – volume: 10 start-page: 59 year: 2010 ident: BF6605642_CR161 publication-title: Nat Rev Cancer doi: 10.1038/nrc2771 – volume: 16 start-page: 6611 year: 2008 ident: BF6605642_CR31 publication-title: Bioorg Med Chem doi: 10.1016/j.bmc.2008.05.021 – volume: 39 start-page: 24 year: 2000 ident: BF6605642_CR191 publication-title: Contemp Top Lab Anim Sci – volume: 29 start-page: 418 year: 2001 ident: BF6605642_CR88 publication-title: Nat Genet doi: 10.1038/ng747 – volume: 8 start-page: 359 year: 2008 ident: BF6605642_CR204 publication-title: Curr Opin Pharmacol doi: 10.1016/j.coph.2008.07.007 – volume: 11 start-page: 7023 year: 2005 ident: BF6605642_CR9 publication-title: Clin Cancer Res doi: 10.1158/1078-0432.CCR-05-0518 – volume: 35 start-page: 1 year: 2001 ident: BF6605642_CR118 publication-title: Lab Anim doi: 10.1258/0023677011911345 – volume: 9 start-page: 274 year: 2009 ident: BF6605642_CR124 publication-title: Nat Rev Cancer doi: 10.1038/nrc2622 – volume: 21 start-page: 15 year: 2001 ident: BF6605642_CR43 publication-title: J Appl Toxicol doi: 10.1002/jat.727 – volume: 38 start-page: 286 year: 2004 ident: BF6605642_CR155 publication-title: Lab Anim doi: 10.1258/002367704323133673 – volume: 77 start-page: 640 year: 1998 ident: BF6605642_CR106 publication-title: Int J Cancer doi: 10.1002/(SICI)1097-0215(19980812)77:4<640::AID-IJC26>3.0.CO;2-8 – volume: 29 start-page: 269 year: 2004 ident: BF6605642_CR61 publication-title: Immunol Res doi: 10.1385/IR:29:1-3:269 – volume: 143 start-page: 1055 year: 1993 ident: BF6605642_CR102 publication-title: Am J Pathol – volume: 9 start-page: 55 year: 2009 ident: BF6605642_CR130 publication-title: Am J Bioeth doi: 10.1080/15265160903318343 – volume: 58 start-page: 621 year: 2006 ident: BF6605642_CR28 publication-title: Pharmacol Rev doi: 10.1124/pr.58.3.10 – volume: 9 start-page: 257 year: 2010 ident: BF6605642_CR132 publication-title: Mol Cancer Ther doi: 10.1158/1535-7163.MCT-09-0743 – volume: 22 start-page: 473 year: 1992 ident: BF6605642_CR201 publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/0360-3016(92)90856-D – volume: 209 start-page: 178 year: 1997 ident: BF6605642_CR7 publication-title: Klin Padiatr doi: 10.1055/s-2008-1043947 – volume: 52 start-page: 5395 year: 1992 ident: BF6605642_CR119 publication-title: Cancer Res – volume: 4 start-page: e4992 year: 2009 ident: BF6605642_CR174 publication-title: PLoS One doi: 10.1371/journal.pone.0004992 – volume: 10 start-page: 789 year: 2004 ident: BF6605642_CR190 publication-title: Nat Med doi: 10.1038/nm1087 – volume: 40 start-page: 111 year: 2006 ident: BF6605642_CR198 publication-title: Lab Anim doi: 10.1258/002367706776318971 – reference: 20502459 - Br J Cancer. 2010 May 25;102(11):1553-4. doi: 10.1038/sj.bjc.6605692. |
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| Title | Guidelines for the welfare and use of animals in cancer research |
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