Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer
Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%–5% and the risk for devel...
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| Vydané v: | International journal of molecular sciences Ročník 18; číslo 1; s. 197 |
|---|---|
| Hlavní autori: | , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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Switzerland
MDPI AG
19.01.2017
MDPI |
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| ISSN: | 1422-0067, 1661-6596, 1422-0067 |
| On-line prístup: | Získať plný text |
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| Abstract | Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%–5% and the risk for developing CRC is associated with personal features or habits such as age, chronic disease history and lifestyle. In this context, the gut microbiota has a relevant role, and dysbiosis situations can induce colonic carcinogenesis through a chronic inflammation mechanism. Some of the bacteria responsible for this multiphase process include Fusobacterium spp, Bacteroides fragilis and enteropathogenic Escherichia coli. CRC is caused by mutations that target oncogenes, tumour suppressor genes and genes related to DNA repair mechanisms. Depending on the origin of the mutation, colorectal carcinomas can be classified as sporadic (70%); inherited (5%) and familial (25%). The pathogenic mechanisms leading to this situation can be included in three types, namely chromosomal instability (CIN), microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Within these types of CRC, common mutations, chromosomal changes and translocations have been reported to affect important pathways (WNT, MAPK/PI3K, TGF-β, TP53), and mutations; in particular, genes such as c-MYC, KRAS, BRAF, PIK3CA, PTEN, SMAD2 and SMAD4 can be used as predictive markers for patient outcome. In addition to gene mutations, alterations in ncRNAs, such as lncRNA or miRNA, can also contribute to different steps of the carcinogenesis process and have a predictive value when used as biomarkers. In consequence, different panels of genes and mRNA are being developed to improve prognosis and treatment selection. The choice of first-line treatment in CRC follows a multimodal approach based on tumour-related characteristics and usually comprises surgical resection followed by chemotherapy combined with monoclonal antibodies or proteins against vascular endothelial growth factor (VEGF) and epidermal growth receptor (EGFR). Besides traditional chemotherapy, alternative therapies (such as agarose tumour macrobeads, anti-inflammatory drugs, probiotics, and gold-based drugs) are currently being studied to increase treatment effectiveness and reduce side effects. |
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| AbstractList | Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%-5% and the risk for developing CRC is associated with personal features or habits such as age, chronic disease history and lifestyle. In this context, the gut microbiota has a relevant role, and dysbiosis situations can induce colonic carcinogenesis through a chronic inflammation mechanism. Some of the bacteria responsible for this multiphase process include Fusobacterium spp, Bacteroides fragilis and enteropathogenic Escherichia coli. CRC is caused by mutations that target oncogenes, tumour suppressor genes and genes related to DNA repair mechanisms. Depending on the origin of the mutation, colorectal carcinomas can be classified as sporadic (70%); inherited (5%) and familial (25%). The pathogenic mechanisms leading to this situation can be included in three types, namely chromosomal instability (CIN), microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Within these types of CRC, common mutations, chromosomal changes and translocations have been reported to affect important pathways (WNT, MAPK/PI3K, TGF-β, TP53), and mutations; in particular, genes such as c-MYC, KRAS, BRAF, PIK3CA, PTEN, SMAD2 and SMAD4 can be used as predictive markers for patient outcome. In addition to gene mutations, alterations in ncRNAs, such as lncRNA or miRNA, can also contribute to different steps of the carcinogenesis process and have a predictive value when used as biomarkers. In consequence, different panels of genes and mRNA are being developed to improve prognosis and treatment selection. The choice of first-line treatment in CRC follows a multimodal approach based on tumour-related characteristics and usually comprises surgical resection followed by chemotherapy combined with monoclonal antibodies or proteins against vascular endothelial growth factor (VEGF) and epidermal growth receptor (EGFR). Besides traditional chemotherapy, alternative therapies (such as agarose tumour macrobeads, anti-inflammatory drugs, probiotics, and gold-based drugs) are currently being studied to increase treatment effectiveness and reduce side effects. Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%-5% and the risk for developing CRC is associated with personal features or habits such as age, chronic disease history and lifestyle. In this context, the gut microbiota has a relevant role, and dysbiosis situations can induce colonic carcinogenesis through a chronic inflammation mechanism. Some of the bacteria responsible for this multiphase process include Fusobacterium spp, Bacteroides fragilis and enteropathogenic Escherichia coli. CRC is caused by mutations that target oncogenes, tumour suppressor genes and genes related to DNA repair mechanisms. Depending on the origin of the mutation, colorectal carcinomas can be classified as sporadic (70%); inherited (5%) and familial (25%). The pathogenic mechanisms leading to this situation can be included in three types, namely chromosomal instability (CIN), microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Within these types of CRC, common mutations, chromosomal changes and translocations have been reported to affect important pathways (WNT, MAPK/PI3K, TGF-[beta], TP53), and mutations; in particular, genes such as c-MYC, KRAS, BRAF, PIK3CA, PTEN, SMAD2 and SMAD4 can be used as predictive markers for patient outcome. In addition to gene mutations, alterations in ncRNAs, such as lncRNA or miRNA, can also contribute to different steps of the carcinogenesis process and have a predictive value when used as biomarkers. In consequence, different panels of genes and mRNA are being developed to improve prognosis and treatment selection. The choice of first-line treatment in CRC follows a multimodal approach based on tumour-related characteristics and usually comprises surgical resection followed by chemotherapy combined with monoclonal antibodies or proteins against vascular endothelial growth factor (VEGF) and epidermal growth receptor (EGFR). Besides traditional chemotherapy, alternative therapies (such as agarose tumour macrobeads, anti-inflammatory drugs, probiotics, and gold-based drugs) are currently being studied to increase treatment effectiveness and reduce side effects. Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%-5% and the risk for developing CRC is associated with personal features or habits such as age, chronic disease history and lifestyle. In this context, the gut microbiota has a relevant role, and dysbiosis situations can induce colonic carcinogenesis through a chronic inflammation mechanism. Some of the bacteria responsible for this multiphase process include Fusobacterium spp, Bacteroides fragilis and enteropathogenic Escherichia coli. CRC is caused by mutations that target oncogenes, tumour suppressor genes and genes related to DNA repair mechanisms. Depending on the origin of the mutation, colorectal carcinomas can be classified as sporadic (70%); inherited (5%) and familial (25%). The pathogenic mechanisms leading to this situation can be included in three types, namely chromosomal instability (CIN), microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Within these types of CRC, common mutations, chromosomal changes and translocations have been reported to affect important pathways (WNT, MAPK/PI3K, TGF-β, TP53), and mutations; in particular, genes such as c-MYC, KRAS, BRAF, PIK3CA, PTEN, SMAD2 and SMAD4 can be used as predictive markers for patient outcome. In addition to gene mutations, alterations in ncRNAs, such as lncRNA or miRNA, can also contribute to different steps of the carcinogenesis process and have a predictive value when used as biomarkers. In consequence, different panels of genes and mRNA are being developed to improve prognosis and treatment selection. The choice of first-line treatment in CRC follows a multimodal approach based on tumour-related characteristics and usually comprises surgical resection followed by chemotherapy combined with monoclonal antibodies or proteins against vascular endothelial growth factor (VEGF) and epidermal growth receptor (EGFR). Besides traditional chemotherapy, alternative therapies (such as agarose tumour macrobeads, anti-inflammatory drugs, probiotics, and gold-based drugs) are currently being studied to increase treatment effectiveness and reduce side effects.Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%-5% and the risk for developing CRC is associated with personal features or habits such as age, chronic disease history and lifestyle. In this context, the gut microbiota has a relevant role, and dysbiosis situations can induce colonic carcinogenesis through a chronic inflammation mechanism. Some of the bacteria responsible for this multiphase process include Fusobacterium spp, Bacteroides fragilis and enteropathogenic Escherichia coli. CRC is caused by mutations that target oncogenes, tumour suppressor genes and genes related to DNA repair mechanisms. Depending on the origin of the mutation, colorectal carcinomas can be classified as sporadic (70%); inherited (5%) and familial (25%). The pathogenic mechanisms leading to this situation can be included in three types, namely chromosomal instability (CIN), microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Within these types of CRC, common mutations, chromosomal changes and translocations have been reported to affect important pathways (WNT, MAPK/PI3K, TGF-β, TP53), and mutations; in particular, genes such as c-MYC, KRAS, BRAF, PIK3CA, PTEN, SMAD2 and SMAD4 can be used as predictive markers for patient outcome. In addition to gene mutations, alterations in ncRNAs, such as lncRNA or miRNA, can also contribute to different steps of the carcinogenesis process and have a predictive value when used as biomarkers. In consequence, different panels of genes and mRNA are being developed to improve prognosis and treatment selection. The choice of first-line treatment in CRC follows a multimodal approach based on tumour-related characteristics and usually comprises surgical resection followed by chemotherapy combined with monoclonal antibodies or proteins against vascular endothelial growth factor (VEGF) and epidermal growth receptor (EGFR). Besides traditional chemotherapy, alternative therapies (such as agarose tumour macrobeads, anti-inflammatory drugs, probiotics, and gold-based drugs) are currently being studied to increase treatment effectiveness and reduce side effects. Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer-related death. Most cases of CRC are detected in Western countries, with its incidence increasing year by year. The probability of suffering from colorectal cancer is about 4%-5% and the risk for developing CRC is associated with personal features or habits such as age, chronic disease history and lifestyle. In this context, the gut microbiota has a relevant role, and dysbiosis situations can induce colonic carcinogenesis through a chronic inflammation mechanism. Some of the bacteria responsible for this multiphase process include spp, and enteropathogenic . CRC is caused by mutations that target oncogenes, tumour suppressor genes and genes related to DNA repair mechanisms. Depending on the origin of the mutation, colorectal carcinomas can be classified as sporadic (70%); inherited (5%) and familial (25%). The pathogenic mechanisms leading to this situation can be included in three types, namely chromosomal instability (CIN), microsatellite instability (MSI) and CpG island methylator phenotype (CIMP). Within these types of CRC, common mutations, chromosomal changes and translocations have been reported to affect important pathways (WNT, MAPK/PI3K, TGF-β, TP53), and mutations; in particular, genes such as c-MYC, , , , , and can be used as predictive markers for patient outcome. In addition to gene mutations, alterations in ncRNAs, such as lncRNA or miRNA, can also contribute to different steps of the carcinogenesis process and have a predictive value when used as biomarkers. In consequence, different panels of genes and mRNA are being developed to improve prognosis and treatment selection. The choice of first-line treatment in CRC follows a multimodal approach based on tumour-related characteristics and usually comprises surgical resection followed by chemotherapy combined with monoclonal antibodies or proteins against vascular endothelial growth factor (VEGF) and epidermal growth receptor (EGFR). Besides traditional chemotherapy, alternative therapies (such as agarose tumour macrobeads, anti-inflammatory drugs, probiotics, and gold-based drugs) are currently being studied to increase treatment effectiveness and reduce side effects. |
| Author | Rodriguez Yoldi, María Pradilla Dieste, Alberto Mármol, Inés Sánchez-de-Diego, Cristina Cerrada, Elena |
| AuthorAffiliation | 1 Departamento de Farmacología y Fisiología, Facultad de Veterinaria, Universidad de Zaragoza, 50013 Zaragoza, Spain; ines.marmol9@gmail.com (I.M.); csanchezdg@gmail.com (C.S.-d.-D.); albertopradilladieste@gmail.com (A.P.D.) 4 Ciber de Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto Agroalimentario de Aragón (IA2), (Instituto de Investigaciones Sanitarias de Aragón IIS Aragó)n, 50008 Zaragoza, Spain 2 Departament de Ciencies Fisiologiques II, Universitat de Barcelona, L’hospitalet de Llobregat, 08007 Barcelona, Spain 3 Departamento de Química Inorgánica, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, Spain; ecerrada@unizar.es |
| AuthorAffiliation_xml | – name: 3 Departamento de Química Inorgánica, Facultad de Ciencias, Universidad de Zaragoza, 50009 Zaragoza, Spain; ecerrada@unizar.es – name: 2 Departament de Ciencies Fisiologiques II, Universitat de Barcelona, L’hospitalet de Llobregat, 08007 Barcelona, Spain – name: 4 Ciber de Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto Agroalimentario de Aragón (IA2), (Instituto de Investigaciones Sanitarias de Aragón IIS Aragó)n, 50008 Zaragoza, Spain – name: 1 Departamento de Farmacología y Fisiología, Facultad de Veterinaria, Universidad de Zaragoza, 50013 Zaragoza, Spain; ines.marmol9@gmail.com (I.M.); csanchezdg@gmail.com (C.S.-d.-D.); albertopradilladieste@gmail.com (A.P.D.) |
| Author_xml | – sequence: 1 givenname: Inés surname: Mármol fullname: Mármol, Inés – sequence: 2 givenname: Cristina surname: Sánchez-de-Diego fullname: Sánchez-de-Diego, Cristina – sequence: 3 givenname: Alberto surname: Pradilla Dieste fullname: Pradilla Dieste, Alberto – sequence: 4 givenname: Elena orcidid: 0000-0003-2457-3674 surname: Cerrada fullname: Cerrada, Elena – sequence: 5 givenname: María surname: Rodriguez Yoldi fullname: Rodriguez Yoldi, María |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28106826$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1038/ismej.2011.109 10.1016/S1673-8527(09)60053-9 10.1111/j.1572-0241.2001.04677.x 10.1200/JCO.2008.21.3744 10.1098/rstb.2014.0298 10.1517/13543784.15.9.1067 10.1016/j.febslet.2008.05.012 10.1007/s40268-015-0083-y 10.3748/wjg.v20.i48.18121 10.1016/j.biopha.2015.08.006 10.1017/S0022215113000947 10.1016/j.ejca.2005.04.039 10.1016/S0140-6736(04)17514-4 10.1200/JCO.2011.35.4498 10.1186/s12885-015-1345-3 10.1373/clinchem.2006.068577 10.1038/nature08975 10.1016/j.bbrc.2015.06.041 10.1590/S0102-86502016001300004 10.1016/j.phrs.2016.01.001 10.1002/jso.23806 10.1210/jc.2003-030222 10.1093/hmg/ddl046 10.1093/jnci/djv246 10.1016/j.jaad.2010.06.014 10.3748/wjg.v22.i11.3227 10.2741/s274 10.1126/science.1155725 10.1007/s00248-013-0245-9 10.1158/2159-8290.CD-14-0501 10.1007/s11274-013-1499-6 10.1016/j.canlet.2016.01.037 10.1007/s13277-014-2890-0 10.1017/S0007114511004934 10.1016/S1470-2045(10)70130-3 10.1200/JCO.2000.18.16.2938 10.1038/sj.bjc.6602358 10.1073/pnas.1400350111 10.1002/(SICI)1097-0142(19960701)78:1<48::AID-CNCR9>3.0.CO;2-D 10.2174/1389201011314030004 10.3892/etm.2015.2538 10.1038/sj.bjc.6606054 10.1016/j.ejim.2015.03.008 10.1111/j.1753-4887.2012.00493.x 10.3748/wjg.v20.i4.908 10.1054/bjoc.2001.2095 10.1016/S0140-6736(10)60353-4 10.4161/oxim.2.5.9498 10.4018/978-1-4666-6611-5.ch002 10.1002/ijc.26193 10.1016/j.imlet.2014.05.014 10.1097/SLA.0b013e31827c1180 10.1002/jgm.670 10.1038/nature11252 10.1016/j.canlet.2011.09.033 10.1053/j.gastro.2012.07.090 10.1093/jnci/djq306 10.1053/j.gastro.2009.12.065 10.1073/pnas.0801613105 10.1038/nbt.1914 10.1038/nature12820 10.1042/BJ20141337 10.1038/sj.onc.1210856 10.1186/1471-2407-14-802 10.1096/fj.10-177808 10.1158/1078-0432.CCR-13-1769 10.1002/ijc.24910 10.18632/oncotarget.4423 10.18632/oncotarget.6545 10.1136/jmg.37.8.588 10.1093/annonc/mdq222 10.1111/jphp.12372 10.1177/1756283X12473674 10.1007/s13277-015-4724-0 10.1155/2011/792362 10.1016/j.chom.2013.12.010 10.1136/gut.48.4.526 10.1007/s10350-004-0628-6 10.2174/138955712802762040 10.1371/journal.pone.0087456 10.5217/ir.2016.14.2.127 10.1016/j.foodchem.2014.01.105 10.1002/ijc.26485 10.3390/nu6125786 10.1016/j.cbpa.2014.02.003 10.1038/nature11053 10.1016/j.ejphar.2014.07.025 10.1056/NEJMoa050405 10.1093/cid/ciu787 10.1001/jama.293.2.233 10.1200/JCO.2006.10.5437 10.1093/jnci/djh034 10.1111/j.1349-7006.2006.00305.x 10.1111/j.1462-2920.2007.01369.x 10.1001/jama.2008.839 10.1016/j.tim.2012.12.001 10.1371/journal.pone.0065479 10.3892/mmr.2016.4788 10.1200/jco.2013.31.15_suppl.e14517 10.1039/C2CC37366A 10.1371/journal.pone.0124487 10.1038/ejcn.2011.141 10.1016/j.canep.2014.07.003 10.2174/0929867321666131217161849 10.18388/abp.2002_3768 10.1099/jmm.0.048975-0 10.1016/j.jinorgbio.2013.09.019 10.1111/j.1365-2036.2006.02854.x 10.2165/00003495-198427050-00002 10.1158/1055-9965.EPI-08-0937 10.1038/sj.onc.1207262 10.1016/0092-8674(90)90186-I 10.1007/s10620-015-4029-6 10.1007/978-3-0348-0837-8_2 10.1056/NEJMra012242 10.1002/cam4.97 10.1093/carcin/bgp181 10.1016/j.toxlet.2015.06.012 10.2174/156802611794785226 10.1038/nrgastro.2011.173 10.1111/j.1572-0241.2007.01126.x 10.3892/ijo.2016.3414 10.1093/carcin/bgr114 10.1186/1476-4598-10-38 10.1038/bjc.2013.698 10.1038/ng1834 10.1158/0008-5472.CAN-10-2258 10.1007/s00775-016-1338-y 10.1021/om400340a 10.1186/s12967-016-0772-5 10.1023/A:1015090124153 10.1200/JCO.2012.47.3116 10.1200/JCO.2008.19.5024 10.1038/nrc1739 10.4331/wjbc.v6.i4.290 10.1142/S1088424615500236 10.1158/1940-6207.CAPR-11-0222 10.1016/j.lwt.2016.02.040 10.1136/gut.2008.155473 10.1016/j.cgh.2013.08.015 10.1159/000444493 10.1111/j.1472-765X.2006.01913.x 10.1158/1078-0432.CCR-05-0171 10.1016/j.molcel.2013.11.004 10.1093/nar/gkt182 10.1039/c0dt00292e 10.1093/nar/gkq1138 10.1002/1097-0142(19930815)72:4<1171::AID-CNCR2820720407>3.0.CO;2-D 10.1101/gr.152942.112 10.1038/ncomms7528 10.1038/ncomms7342 10.1007/BF03256309 10.1007/s00018-015-2004-1 10.1016/j.ejmech.2014.04.001 10.1002/cncr.27628 10.1186/1756-9966-29-128 10.1038/nature09144 10.1038/sj.onc.1206933 10.1016/j.chom.2013.07.007 10.1093/annonc/mdm583 10.1016/j.foodchem.2016.03.085 10.1128/mBio.00692-13 10.1016/j.jff.2015.06.018 10.1080/01635580701684872 10.2174/156802612799078964 10.3748/wjg.v21.i4.1275 10.1007/s12032-013-0588-6 10.1200/JCO.2004.08.186 10.1038/nrd1691 10.1098/rsta.2014.0185 10.3892/mmr.2015.4557 10.5858/arpa.2011-0035-RA 10.1371/journal.pgen.1002071 10.1634/theoncologist.2013-0401 10.1016/j.molcel.2012.09.025 10.1089/ars.2012.4757 10.1017/S0007114514004127 10.1136/jcp.2004.023648 10.1172/JCI72334 10.3322/CA.2007.0018 10.1016/j.anaerobe.2013.04.006 10.1016/j.copbio.2015.08.015 10.1016/j.clcc.2011.10.004 10.1371/journal.pone.0090731 10.2174/1871520615666150129211440 10.1111/cpr.12237 10.1186/1756-9966-32-104 10.1158/1078-0432.CCR-11-2410 10.18632/oncotarget.8937 10.1016/j.tcb.2008.09.002 10.1016/j.dld.2015.07.008 10.1007/s13277-015-3750-2 10.1007/s11886-014-0540-1 10.1093/annonc/mdu100 10.1200/jco.2015.33.15_suppl.e22006 10.1021/jf9801973 10.1002/mc.22137 10.1016/j.molcel.2013.01.010 10.1038/nature13311 10.1007/s13238-015-0187-8 10.1021/jf101394w 10.1002/path.3014 10.1039/C5DT01802A 10.1053/j.gastro.2009.12.064 10.1002/prca.201400082 10.1634/theoncologist.10-4-250 10.1007/s00432-012-1324-x 10.3748/wjg.v22.i2.557 10.1002/ijc.24191 10.1001/jama.284.10.1247 10.1200/JCO.2010.30.1077 10.1158/0008-5472.CAN-08-2466 10.1093/bioinformatics/btt014 10.1245/s10434-008-9961-7 10.1016/j.syapm.2015.03.004 10.1111/j.1349-7006.2010.01737.x 10.1158/1055-9965.EPI-10-0027 10.1146/annurev-med-051513-102539 10.4161/gmic.29330 10.2174/138161210791209009 10.1017/S0007114512001948 10.1081/FRI-200040606 10.1038/521S1a 10.1158/1078-0432.CCR-14-2779 10.1097/MEG.0b013e328306a3a2 10.3390/ijms16047493 10.1186/s12879-014-0733-7 10.3945/ajcn.112.056689 10.1007/s11912-014-0406-0 10.1053/j.gastro.2008.07.076 10.1016/j.freeradbiomed.2006.12.021 10.1371/journal.pone.0159136 10.1016/S0165-4608(01)00634-3 10.15403/jgld.2014.1121.244.375 10.1016/j.yexmp.2015.06.014 10.1158/1078-0432.CCR-13-1343 10.1016/j.nutres.2013.07.018 10.1200/JCO.2005.05.0229 10.7326/0003-4819-115-12-952 10.3181/0712-MR-336 10.1093/carcin/bgr213 10.18632/oncotarget.4750 10.3748/wjg.v20.i24.7878 10.1177/1947601911431081 10.1158/1940-6207.CAPR-10-0113 10.1016/j.coi.2010.06.008 10.1093/annonc/mdn786 10.1093/nar/gku988 10.3892/etm.2015.2846 10.1007/s11523-014-0319-8 10.1016/j.mrrev.2003.07.005 10.1038/nrg3722 10.1002/jcb.22394 10.1016/j.trstmh.2008.04.010 10.1002/ijc.29607 10.1093/alcalc/agh057 10.3934/biophy.2015.4.794 10.1158/1055-9965.EPI-06-0994 10.1038/srep00170 10.1186/s13099-016-0099-z 10.5935/0101-2800.20130052 10.18632/oncoscience.167 10.1039/c2dt11781a 10.1016/j.biocel.2006.07.001 10.3892/ijo.2016.3430 10.1155/2004/136734 10.1002/ejic.201600177 10.1371/journal.pone.0053653 10.1093/hmg/ddt398 10.1038/35094017 10.2174/092986709787909587 10.1016/j.freeradbiomed.2009.12.022 10.1158/0008-5472.CAN-13-3159 10.1093/carcin/bgu071 10.1038/nrc3610 |
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| References | Wheeler (ref_192) 2000; 37 Popat (ref_48) 2005; 41 ref_92 Ling (ref_98) 2013; 23 Diamandis (ref_180) 2010; 102 Amable (ref_278) 2016; 106 ref_130 Suh (ref_231) 1993; 72 Candela (ref_156) 2014; 20 ref_256 ref_255 Nakano (ref_103) 2006; 97 Karasawa (ref_274) 2015; 237 Zhao (ref_70) 2016; 48 Bertucci (ref_210) 2004; 23 Sveen (ref_218) 2013; 19 Pibouin (ref_101) 2002; 133 Tang (ref_58) 2011; 32 Prensner (ref_108) 2011; 29 Ley (ref_129) 2008; 320 Klintenas (ref_189) 2004; 25 Hu (ref_283) 2014; 21 Yaeger (ref_42) 2015; 21 Solomon (ref_238) 2005; 352 Kahouli (ref_241) 2013; 62 ref_120 ref_122 Willett (ref_31) 2012; 487 Ou (ref_174) 2013; 98 Ungprasert (ref_234) 2015; 26 Wang (ref_61) 2012; 314 Kim (ref_139) 2014; 15 Wang (ref_147) 2012; 6 Okreglicka (ref_171) 2015; 66 Atreya (ref_46) 2013; 2 Circu (ref_249) 2010; 48 Stoffel (ref_12) 2014; 12 Kim (ref_97) 2014; 111 Tsang (ref_88) 2010; 31 Gupta (ref_235) 2001; 1 Levin (ref_13) 2008; 58 Gupta (ref_91) 2010; 464 Goldstein (ref_39) 2014; 25 Wu (ref_145) 2013; 66 ref_273 Smith (ref_227) 2011; 71 Shahidi (ref_261) 2015; 18 ref_75 Marshall (ref_211) 2010; 126 Nordlinger (ref_222) 2010; 21 Park (ref_67) 2016; 48 Sheflin (ref_146) 2014; 16 Yang (ref_96) 2013; 139 Figer (ref_281) 2000; 18 Uen (ref_209) 2008; 15 Wang (ref_196) 2004; 22 (ref_18) 2016; 14 ref_262 Fearon (ref_9) 1990; 61 Seitz (ref_22) 2004; 39 Jacobs (ref_200) 2009; 27 Brody (ref_7) 2015; 521 Johns (ref_16) 2001; 96 Cervantes (ref_223) 2014; 5 Sears (ref_163) 2014; 124 Sastre (ref_207) 2008; 19 Mahmood (ref_294) 2013; 19 Rennoll (ref_34) 2015; 6 Yamakuchi (ref_53) 2008; 105 Nie (ref_85) 2012; 4 Umetani (ref_194) 2006; 52 ref_215 Sena (ref_250) 2012; 48 Qiu (ref_71) 2016; 49 Bashir (ref_162) 2016; 37 Donohoe (ref_179) 2014; 4 Sobhani (ref_153) 2013; 6 Chaffman (ref_287) 1984; 27 Karamountzos (ref_202) 2007; 102 Sah (ref_247) 2014; 156 Canavan (ref_15) 2006; 23 Siddik (ref_277) 2003; 22 Botteri (ref_23) 2008; 300 Ludwig (ref_181) 2005; 5 Strier (ref_240) 2005; 11 Martini (ref_191) 2009; 69 Dasari (ref_266) 2014; 740 Krishnan (ref_136) 2015; 36 Song (ref_59) 2012; 131 Hofmanova (ref_178) 2013; 14 Wenzel (ref_259) 2000; 60 Nosho (ref_158) 2016; 22 Cohen (ref_208) 2009; 20 Zaharie (ref_77) 2015; 24 Matouk (ref_94) 2009; 21 Brocardo (ref_32) 2008; 18 Sarli (ref_47) 2004; 47 Li (ref_72) 2016; 37 Claes (ref_186) 2010; 11 Yang (ref_118) 2015; 36 Baker (ref_201) 2011; 104 Cox (ref_132) 2013; 22 Cunningham (ref_8) 2010; 375 Xu (ref_82) 2015; 10 Rooney (ref_51) 2001; 85 Yang (ref_102) 2014; 53 Ge (ref_110) 2013; 30 Silverstein (ref_237) 2000; 284 Liu (ref_55) 2010; 37 Graham (ref_99) 2011; 2 Takai (ref_197) 2009; 18 Xiao (ref_79) 2015; 74 Zhang (ref_80) 2015; 6 Mattick (ref_52) 2006; 15 Tseng (ref_115) 2014; 512 Umar (ref_11) 2004; 96 Fung (ref_177) 2012; 108 Zhang (ref_298) 2010; 109 Fellig (ref_89) 2005; 58 ref_229 Liu (ref_296) 2015; 2 ref_228 Quaye (ref_204) 2008; 102 Pala (ref_244) 2011; 129 Santarelli (ref_21) 2008; 60 Kislitsin (ref_188) 2002; 47 ref_220 Matamoros (ref_124) 2013; 21 WoYniak (ref_272) 2002; 49 Xie (ref_3) 2013; 29 Li (ref_112) 2013; 32 Zhang (ref_73) 2016; 373 Wang (ref_76) 2015; 7 Wang (ref_78) 2016; 13 Geuking (ref_134) 2014; 5 Takahashi (ref_116) 2014; 110 Barros (ref_251) 2010; 58 Yadav (ref_125) 2016; 8 Kostic (ref_159) 2014; 14 Coghlin (ref_182) 2015; 9 Konstantinopoulos (ref_295) 2006; 15 Lum (ref_285) 2013; 49 Miller (ref_264) 2012; 66 Romanos (ref_301) 2015; 15 Ursell (ref_119) 2012; 70 Chai (ref_151) 2015; 468 Cerrada (ref_300) 2014; 79 David (ref_149) 2014; 505 Bonnet (ref_167) 2014; 20 Lu (ref_54) 2015; 99 Schmitt (ref_286) 2012; 4 Zimmer (ref_148) 2012; 66 Iacopetta (ref_185) 2006; 55 Silveira (ref_276) 2013; 127 Hung (ref_150) 2015; 107 Scarpellini (ref_121) 2011; 47 Munro (ref_50) 2005; 92 Weisenberger (ref_30) 2006; 38 Brown (ref_226) 1999; 59 Peres (ref_275) 2013; 35 Hoff (ref_280) 2012; 11 Quek (ref_1) 2014; 43 Geiersbach (ref_184) 2011; 135 Zhang (ref_95) 2003; 88 Aykan (ref_172) 2015; 9 Aprile (ref_187) 2013; 1 Liu (ref_62) 2011; 32 Ahmed (ref_117) 2013; 10 Choi (ref_246) 2006; 42 Lenehan (ref_219) 2012; 118 Grant (ref_269) 2011; 11 Kadowaki (ref_40) 2015; 21 Shi (ref_258) 2005; 21 Ogino (ref_38) 2009; 58 Smidt (ref_123) 2007; 9 Bai (ref_83) 2015; 137 Muhammad (ref_267) 2014; 19 Herzig (ref_33) 2015; 111 Li (ref_66) 2015; 6 Lynch (ref_10) 2003; 348 Xu (ref_128) 2015; 113 Ryan (ref_152) 2015; 38 Liu (ref_100) 2013; 41 Maak (ref_216) 2013; 257 Li (ref_160) 2016; 22 Cross (ref_24) 2014; 35 Yatsunenko (ref_126) 2012; 486 Koifman (ref_170) 2003; 544 Zackular (ref_157) 2013; 4 ref_303 Amaral (ref_2) 2011; 39 Montero (ref_254) 2016; 70 (ref_155) 2015; 107 Schwabe (ref_154) 2013; 13 Buac (ref_297) 2012; 12 Engen (ref_127) 2015; 37 Serino (ref_138) 2014; 16 Prensner (ref_109) 2014; 74 Zhong (ref_242) 2014; 20 Sankar (ref_131) 2015; 38 Christensen (ref_206) 2002; 8 McDonald (ref_239) 2015; 67 Wang (ref_107) 2008; 582 Grady (ref_26) 2008; 135 Ortego (ref_290) 2014; 130 Almeida (ref_64) 2016; 31 Chung (ref_135) 2010; 22 Poliseno (ref_104) 2010; 465 Kim (ref_173) 2013; 33 Carlson (ref_221) 2009; 13 Willett (ref_19) 2005; 293 Xing (ref_203) 1996; 78 Tomasello (ref_144) 2014; 20 ref_293 ref_56 ref_175 Velioglu (ref_257) 1998; 46 Lv (ref_63) 2016; 23 Valko (ref_248) 2007; 39 ref_176 Marzano (ref_289) 2007; 42 Iebba (ref_140) 2016; 39 (ref_193) 2015; 2015 Hundt (ref_205) 2007; 16 Lammer (ref_284) 2015; 19 Jobin (ref_166) 2014; 162 Barrier (ref_195) 2006; 24 Panagopoulos (ref_106) 2008; 20 Hamilton (ref_86) 2015; 2 Peloquin (ref_143) 2013; 24 Garcia (ref_291) 2016; 21 ref_169 Deng (ref_74) 2016; 61 Morkel (ref_43) 2015; 6 Boland (ref_28) 2010; 138 Galassi (ref_292) 2012; 41 ref_69 Qi (ref_114) 2015; 54 Wheate (ref_271) 2010; 39 Liao (ref_45) 2012; 18 ref_161 Lao (ref_29) 2011; 8 Asangani (ref_57) 2008; 27 ref_164 ref_65 Chen (ref_81) 2015; 463 ref_165 Srivastava (ref_214) 2014; 19 Moore (ref_168) 2010; 11 Han (ref_60) 2012; 226 Noguchi (ref_68) 2016; 90 Day (ref_41) 2015; 10 Chung (ref_111) 2011; 102 Carocho (ref_253) 2016; 207 Pino (ref_27) 2010; 138 Suh (ref_233) 2011; 4 Rigau (ref_232) 1991; 115 Eaden (ref_14) 2001; 48 Xu (ref_93) 2011; 39 Robertson (ref_17) 2012; 143 Nartey (ref_236) 2004; 364 ref_36 Liang (ref_25) 2009; 124 ref_35 Frezza (ref_270) 2010; 16 Wang (ref_279) 2005; 4 Morris (ref_84) 2014; 15 Ohana (ref_90) 2005; 7 Roder (ref_288) 2015; 15 Ferreira (ref_252) 2009; 16 Bacher (ref_183) 2004; 20 Link (ref_198) 2010; 19 Venook (ref_224) 2005; 10 Garza (ref_133) 2015; 72 Chen (ref_245) 2012; 107 Zhang (ref_137) 2015; 16 ref_37 Han (ref_105) 2011; 25 Chong (ref_243) 2014; 30 Zhao (ref_265) 2016; 11 Cerrada (ref_299) 2013; 32 Romanos (ref_302) 2016; 45 Gibb (ref_87) 2011; 10 Garrett (ref_199) 2007; 25 Kitamoto (ref_142) 2016; 14 Yothers (ref_213) 2013; 31 ref_44 Pandey (ref_260) 2009; 2 Wong (ref_190) 2008; 26 Liu (ref_263) 2008; 233 Schippa (ref_141) 2014; 6 Kennedy (ref_217) 2011; 29 Janakiram (ref_230) 2014; 816 Komeda (ref_268) 2012; 12 Popat (ref_49) 2007; 27 Prehn (ref_225) 1991; 51 Yang (ref_113) 2013; 49 Ciombor (ref_282) 2015; 66 ref_5 ref_4 Bastide (ref_20) 2011; 4 Yip (ref_212) 2010; 29 ref_6 10919656 - Cancer Res. 2000 Jul 15;60(14):3823-31 25940732 - Biochem J. 2015 May 15;468(1):1-15 25498959 - Br J Nutr. 2015 Jan;113 Suppl:S1-5 18322143 - CA Cancer J Clin. 2008 May-Jun;58(3):130-60 25266735 - Cancer Discov. 2014 Dec;4(12):1387-97 25540872 - BMC Infect Dis. 2014 Dec 24;14:733 26106599 - Biomed Res Int. 2015;2015:149014 14970275 - J Natl Cancer Inst. 2004 Feb 18;96(4):261-8 16620202 - Lett Appl Microbiol. 2006 May;42(5):452-8 25105360 - J Clin Invest. 2014 Oct;124(10):4166-72 23943792 - Hum Mol Genet. 2013 Oct 15;22(R1):R88-94 26695747 - Alcohol Res. 2015;37(2):223-36 20846378 - J Exp Clin Cancer Res. 2010 Sep 16;29:128 12621137 - N Engl J Med. 2003 Mar 6;348(10):919-32 24648381 - Carcinogenesis. 2014 Jul;35(7):1516-22 24196785 - Br J Cancer. 2014 Jan 7;110(1):164-71 22355685 - Sci Rep. 2011;1:170 15668707 - Br J Cancer. 2005 Feb 14;92(3):434-44 19911377 - J Cell Biochem. 2010 Jan 1;109(1):162-72 12018902 - Dig Dis Sci. 2002 May;47(5):1073-9 20656465 - Curr Opin Immunol. 2010 Aug;22(4):455-60 25311658 - Proteomics Clin Appl. 2015 Feb;9(1-2):64-71 21441351 - FASEB J. 2011 Jul;25(7):2305-12 21098318 - J Clin Oncol. 2011 Jan 1;29(1):17-24 23558749 - Nucleic Acids Res. 2013 May;41(9):4976-87 26254872 - Cell Mol Life Sci. 2015 Nov;72(22):4287-308 25480414 - Tumour Biol. 2015 Apr;36(4):2675-84 23733170 - Microb Ecol. 2013 Aug;66(2):462-70 15051756 - J Clin Oncol. 2004 May 1;22(9):1564-71 24732792 - Eur J Med Chem. 2014 May 22;79:164-72 23640607 - Med Oncol. 2013;30(2):588 21607947 - Int J Cancer. 2011 Dec 1;129(11):2712-9 11890990 - Cancer Genet Cytogenet. 2002 Feb;133(1):55-60 26250158 - Protein Cell. 2015 Sep;6(9):680-8 23651576 - J Laryngol Otol. 2013 Jun;127(6):536-41 19223544 - Cancer Res. 2009 Mar 1;69(5):1851-7 27158266 - Gut Pathog. 2016 May 06;8:17 20555112 - Ann Oncol. 2010 May;21 Suppl 5:v93-7 10979111 - JAMA. 2000 Sep 13;284(10):1247-55 24818718 - Adv Exp Med Biol. 2014;816:25-52 27119506 - Oncotarget. 2016 Jun 14;7(24):35789-35802 23244617 - Antioxid Redox Signal. 2013 Oct 10;19(11):1266-303 20593091 - Dalton Trans. 2010 Sep 21;39(35):8113-27 25886253 - PLoS One. 2015 Apr 17;10(4):e0124487 25650335 - J Pharm Pharmacol. 2015 May;67(5):685-95 19738126 - J Clin Oncol. 2009 Oct 20;27(30):5068-74 26097878 - Oncoscience. 2015 May 31;2(5):457-66 15486743 - Dis Colon Rectum. 2004 Sep;47(9):1467-82 19445043 - Eur J Gastroenterol Hepatol. 2009 Jun;21(6):688-92 25305284 - Clin Infect Dis. 2015 Jan 15;60(2):208-15 26150664 - Philos Trans R Soc Lond B Biol Sci. 2015 Aug 19;370(1675):null 24194538 - MBio. 2013 Nov 05;4(6):e00692-13 26718210 - Tumour Biol. 2016 Mar;37(3):2805-10 25058905 - Eur J Pharmacol. 2014 Oct 5;740:364-78 25929517 - BMC Cancer. 2015 May 01;15:340 22861806 - Nutr Rev. 2012 Aug;70 Suppl 1:S38-44 22699611 - Nature. 2012 May 09;486(7402):222-7 18481151 - Ann Surg Oncol. 2008 Aug;15(8):2120-8 25514560 - Nutrients. 2014 Dec 11;6(12):5786-805 17686012 - Environ Microbiol. 2007 Sep;9(9):2125-36 20874843 - Cancer Sci. 2011 Jan;102(1):245-52 26841791 - J Biol Inorg Chem. 2016 Apr;21(2):275-92 22810696 - Nature. 2012 Jul 18;487(7407):330-7 26257129 - Dig Liver Dis. 2015 Dec;47(12):1007-12 11247898 - Gut. 2001 Apr;48(4):526-35 20420947 - Gastroenterology. 2010 Jun;138(6):2073-2087.e3 14973550 - Oncogene. 2004 Feb 19;23(7):1377-91 2188735 - Cell. 1990 Jun 1;61(5):759-67 24859797 - Target Oncol. 2015 Mar;10(1):99-109 26340103 - Curr Opin Biotechnol. 2015 Dec;36:137-45 21112873 - Nucleic Acids Res. 2011 Jan;39(Database issue):D146-51 26697569 - J Gastrointestin Liver Dis. 2015 Dec;24(4):435-43 15528789 - Dis Markers. 2004;20(4-5):237-50 23785428 - PLoS One. 2013 Jun 13;8(6):e65479 25634450 - Anticancer Agents Med Chem. 2015;15(6):773-82 17320769 - Free Radic Biol Med. 2007 Mar 15;42(6):872-81 27175113 - Intest Res. 2016 Apr;14(2):127-38 18501714 - FEBS Lett. 2008 Jun 11;582(13):1919-27 22154408 - Clin Colorectal Cancer. 2012 Jun;11(2):93-100 22236158 - Curr Top Med Chem. 2012;12(3):219-35 26804248 - Pharmacol Res. 2016 Apr;106:27-36 23395002 - Mol Cell. 2013 Mar 28;49(6):1083-96 22201596 - Curr Pharm Biotechnol. 2013;14(3):274-88 26622375 - Exp Ther Med. 2015 Aug;10(2):683-688 25849657 - Int J Mol Sci. 2015 Apr 02;16(4):7493-519 25862494 - Eur J Intern Med. 2015 May;26(4):285-91 24776770 - Nat Rev Genet. 2014 Jun;15(6):423-37 25589621 - Clin Cancer Res. 2015 Mar 15;21(6):1313-20 18773902 - Gastroenterology. 2008 Oct;135(4):1079-99 23962553 - Clin Gastroenterol Hepatol. 2014 Jul;12(7):1059-68 27142899 - Acta Cir Bras. 2016;31 Suppl 1:13-8 24316222 - Mol Cell. 2014 Jan 9;53(1):88-100 19001346 - J Clin Oncol. 2008 Dec 10;26(35):5668-70 18832519 - Gut. 2009 Jan;58(1):90-6 16978905 - Int J Biochem Cell Biol. 2007;39(1):44-84 24678344 - Ecancermedicalscience. 2014 Jan 24;8:389 26999740 - Oncology. 2016;90(4):221-31 6426923 - Drugs. 1984 May;27(5):378-424 24132111 - Nat Rev Cancer. 2013 Nov;13(11):800-12 20337575 - Curr Pharm Des. 2010 Jun;16(16):1813-25 24267037 - Nutr Res. 2013 Dec;33(12 ):983-94 25043044 - Nature. 2014 Aug 7;512(7512):82-6 17664471 - J Clin Oncol. 2007 Aug 1;25(22):3230-7 11801553 - Clin Cancer Res. 2002 Jan;8(1):156-64 21811294 - Eur J Clin Nutr. 2012 Jan;66(1):53-60 27131314 - Oncol Res. 2016;23 (6):283-90 12422229 - Acta Biochim Pol. 2002;49(3):583-96 24473064 - Cancer Res. 2014 Mar 15;74(6):1651-60 26779313 - Oncol Rev. 2015 Dec 28;9(1):288 17348452 - Anticancer Res. 2007 Jan-Feb;27(1B):627-33 16125380 - Eur J Cancer. 2005 Sep;41(14):2060-70 26259252 - Oncotarget. 2015 Sep 15;6(27):24448-62 25991585 - Int J Cancer. 2015 Nov 15;137(10):2310-22 16651366 - Hum Mol Genet. 2006 Apr 15;15 Spec No 1:R17-29 20426454 - J Agric Food Chem. 2010 May 26;58(10):6277-84 26349975 - Biomed Pharmacother. 2015 Aug;74:138-44 25332394 - Nucleic Acids Res. 2015 Jan;43(Database issue):D168-73 26922981 - New Microbiol. 2016 Jan;39(1):1-12 17047121 - Gut. 2006 Nov;55(11):1671-2 21266362 - Cancer Res. 2011 Feb 1;71(3):725-35 16804544 - Nat Genet. 2006 Jul;38(7):787-93 22391922 - Dalton Trans. 2012 May 7;41(17 ):5307-18 23603043 - Anaerobe. 2013 Dec;24:102-6 24574765 - World J Gastroenterol. 2014 Jan 28;20(4):908-22 20619739 - Lancet Oncol. 2010 Aug;11(8):753-62 1988084 - Cancer Res. 1991 Jan 1;51(1):2-4 23954159 - Cell Host Microbe. 2013 Aug 14;14(2):207-15 27467555 - PLoS One. 2016 Jul 28;11(7):e0159136 25561781 - World J Gastroenterol. 2014 Dec 28;20(48):18121-30 26811607 - World J Gastroenterol. 2016 Jan 14;22(2):557-66 20724028 - J Am Acad Dermatol. 2012 May;66(5):e159-65 21665895 - Carcinogenesis. 2011 Aug;32(8):1207-15 25864640 - Syst Appl Microbiol. 2015 Jun;38(4):276-86 24330491 - J Exp Clin Cancer Res. 2013 Dec 13;32:104 1659272 - Ann Intern Med. 1991 Dec 15;115(12):952-4 18212090 - Ann Oncol. 2008 May;19(5):935-8 21637793 - PLoS Genet. 2011 May;7(5):e1002071 26103003 - Exp Mol Pathol. 2015 Aug;99(1):173-9 26801617 - J Transl Med. 2016 Jan 22;14 :21 23143645 - J Cancer Res Clin Oncol. 2013 Mar;139(3):437-45 21206494 - Br J Cancer. 2011 Feb 1;104(3):488-95 8339210 - Cancer. 1993 Aug 15;72(4):1171-7 22009203 - Nat Rev Gastroenterol Hepatol. 2011 Oct 18;8(12):686-700 14576837 - Oncogene. 2003 Oct 20;22(47):7265-79 14602737 - J Clin Endocrinol Metab. 2003 Nov;88(11):5119-26 25970450 - Nature. 2015 May 14;521(7551):S1 24629967 - Food Chem. 2014 Aug 1;156:264-70 23295318 - Ann Surg. 2013 Jun;257(6):1053-8 19926638 - Carcinogenesis. 2010 Mar;31(3):350-8 19355906 - Curr Med Chem. 2009;16(12):1543-60 26889237 - Exp Ther Med. 2016 Jan;11(1):183-190 20551304 - Cancer Epidemiol Biomarkers Prev. 2010 Jul;19(7):1766-74 21189131 - Curr Top Med Chem. 2011;11(5):521-42 24334760 - Clin Cancer Res. 2014 Feb 15;20(4):859-67 25297801 - J Surg Oncol. 2015 Jan;111(1):96-102 26780942 - Mol Med Rep. 2016 Mar;13(3):2221-8 17968323 - Oncogene. 2008 Apr 3;27(15):2128-36 16611269 - Aliment Pharmacol Ther. 2006 Apr 15;23(8):1097-104 23634186 - Therap Adv Gastroenterol. 2013 May;6(3):215-29 19282466 - Ann Oncol. 2009 Jul;20(7):1223-9 10537279 - Cancer Res. 1999 Oct 15;59(20):5089-92 25632202 - World J Gastroenterol. 2015 Jan 28;21(4):1275-83 21489289 - Mol Cancer. 2011 Apr 13;10:38 11693338 - Am J Gastroenterol. 2001 Oct;96(10):2992-3003 26820227 - Cancer Lett. 2016 Apr 10;373(2):203-13 25341011 - Annu Rev Med. 2015;66:83-95 16189152 - J Clin Pathol. 2005 Oct;58(10):1064-8 16723681 - Clin Chem. 2006 Jun;52(6):1062-9 25123079 - Curr Oncol Rep. 2014 Oct;16(10):406 22931591 - Mini Rev Med Chem. 2012 Oct;12 (12 ):1193-201 17324124 - Am J Gastroenterol. 2007 Apr;102(4):803-13 16239904 - Nat Rev Cancer. 2005 Nov;5(11):845-56 20420946 - Gastroenterology. 2010 Jun;138(6):2059-72 26840372 - Cell Prolif. 2016 Feb;49(1):69-78 23335968 - PLoS One. 2013;8(1):e53653 26935905 - Int J Oncol. 2016 May;48(5):1977-84 22605513 - Cancer. 2012 Nov 1;118(21):5234-44 10922385 - J Med Genet. 2000 Aug;37(8):588-92 20577206 - Nature. 2010 Jun 24;465(7301):1033-8 10944126 - J Clin Oncol. 2000 Aug;18(16):2938-47 21804560 - Nat Biotechnol. 2011 Jul 31;29(8):742-9 20553070 - Asian Pac J Cancer Prev. 2010;11 Suppl 2:81-98 21503572 - Int J Oncol. 2011 Jul;39(1):169-75 16916273 - Expert Opin Investig Drugs. 2006 Sep;15(9):1067-75 21992995 - Br J Nutr. 2012 Jun;107(11):1623-34 22018986 - Cancer Lett. 2012 Jan 28;314(2):223-31 16966692 - J Clin Oncol. 2006 Oct 10;24(29):4685-91 24402113 - J Bras Nefrol. 2013 Oct-Dec;35(4):332-40 24336217 - Nature. 2014 Jan 23;505(7484):559-63 25132422 - Cancer Epidemiol. 2014 Oct;38(5):583-90 26792278 - Dig Dis Sci. 2016 Jun;61(6):1553-60 26024397 - Rocz Panstw Zakl Hig. 2015;66(2):97-105 24608084 - Curr Opin Chem Biol. 2014 Apr;19:144-53 23332725 - Trends Microbiol. 2013 Apr;21(4):167-73 23325619 - Bioinformatics. 2013 Mar 1;29(5):638-44 11900248 - Nat Rev Cancer. 2001 Oct;1(1):11-21 24976724 - World J Gastroenterol. 2014 Jun 28;20(24):7878-86 15644551 - JAMA. 2005 Jan 12;293(2):233-4 14688025 - Carcinogenesis. 2004 Apr;25(4):527-33 18486167 - Trans R Soc Trop Med Hyg. 2008 Aug;102(8):735-42 25919227 - Nat Commun. 2015 Apr 28;6:6342 26071354 - Biochem Biophys Res Commun. 2015 Aug 7;463(4):954-60 22393467 - Genes Cancer. 2011 Aug;2(8):829-40 24972311 - Immunol Lett. 2014 Dec;162(2 Pt A):54-61 15821245 - Oncologist. 2005 Apr;10 |
| References_xml | – volume: 6 start-page: 320 year: 2012 ident: ref_147 article-title: Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers publication-title: ISME J. doi: 10.1038/ismej.2011.109 – volume: 25 start-page: 527 year: 2004 ident: ref_189 article-title: Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas publication-title: Carcinogenesis – volume: 37 start-page: 347 year: 2010 ident: ref_55 article-title: The role of microRNAs in colorectal cancer publication-title: J. Genet. Genom. doi: 10.1016/S1673-8527(09)60053-9 – volume: 96 start-page: 2992 year: 2001 ident: ref_16 article-title: A systematic review and meta-analysis of familial colorectal cancer risk publication-title: Am. J. Gastroenterol. doi: 10.1111/j.1572-0241.2001.04677.x – volume: 27 start-page: 5068 year: 2009 ident: ref_200 article-title: Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2008.21.3744 – ident: ref_120 doi: 10.1098/rstb.2014.0298 – volume: 15 start-page: 1067 year: 2006 ident: ref_295 article-title: The potential of proteasome inhibition in the treatment of colon cancer publication-title: Expert Opin. Investig. Drugs doi: 10.1517/13543784.15.9.1067 – volume: 582 start-page: 1919 year: 2008 ident: ref_107 article-title: UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion publication-title: FEBS Lett. doi: 10.1016/j.febslet.2008.05.012 – volume: 15 start-page: 13 year: 2015 ident: ref_288 article-title: Auranofin: Repurposing an old drug for a golden new age publication-title: Drugs R&D doi: 10.1007/s40268-015-0083-y – volume: 20 start-page: 18121 year: 2014 ident: ref_144 article-title: Dismicrobism in inflammatory bowel disease and colorectal cancer: Changes in response of colocytes publication-title: World J. Gastroenterol. doi: 10.3748/wjg.v20.i48.18121 – volume: 74 start-page: 138 year: 2015 ident: ref_79 article-title: miRNA-144 suppresses proliferation and migration of colorectal cancer cells through GSPT1 publication-title: Biomed. Pharmacother. doi: 10.1016/j.biopha.2015.08.006 – volume: 107 start-page: 659 year: 2015 ident: ref_155 article-title: Role of colonic microbiota in colorectal carcinogenesis: A systematic review publication-title: Rev. Esp. Enferm. Dig. – volume: 127 start-page: 536 year: 2013 ident: ref_276 article-title: Mechanisms of cisplatin ototoxicity: Theoretical review publication-title: J. Laryngol. Otol. doi: 10.1017/S0022215113000947 – volume: 41 start-page: 2060 year: 2005 ident: ref_48 article-title: A systematic review and meta-analysis of the relationship between chromosome 18q genotype, DCC status and colorectal cancer prognosis publication-title: Eur. J. Cancer doi: 10.1016/j.ejca.2005.04.039 – volume: 364 start-page: 2021 year: 2004 ident: ref_236 article-title: Risk of cardiovascular events and rofecoxib: Cumulative meta-analysis publication-title: Lancet doi: 10.1016/S0140-6736(04)17514-4 – volume: 29 start-page: 4620 year: 2011 ident: ref_217 article-title: Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2011.35.4498 – ident: ref_37 doi: 10.1186/s12885-015-1345-3 – volume: 11 start-page: 81 year: 2010 ident: ref_168 article-title: Cancer epidemiology and control in peninsular and island South-east Asia-past, present and future publication-title: Asian Pac. J. Cancer Prev. – volume: 52 start-page: 1062 year: 2006 ident: ref_194 article-title: Increased integrity of free circulating DNA in sera of patients with colorectal or periampullary cancer: Direct quantitative PCR for alu repeats publication-title: Clin. Chem. doi: 10.1373/clinchem.2006.068577 – volume: 464 start-page: 1071 year: 2010 ident: ref_91 article-title: Long non-coding RNA hotair reprograms chromatin state to promote cancer metastasis publication-title: Nature doi: 10.1038/nature08975 – volume: 463 start-page: 954 year: 2015 ident: ref_81 article-title: microRNA-101 down-regulates sphingosine kinase 1 in colorectal cancer cells publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2015.06.041 – volume: 31 start-page: 13 year: 2016 ident: ref_64 article-title: Serological under expression of microRNA-21, microRNA-34a and microRNA-126 in colorectal cancer publication-title: Acta Cir. Bras. doi: 10.1590/S0102-86502016001300004 – volume: 106 start-page: 27 year: 2016 ident: ref_278 article-title: Cisplatin resistance and opportunities for precision medicine publication-title: Pharmacol. Res. doi: 10.1016/j.phrs.2016.01.001 – volume: 111 start-page: 96 year: 2015 ident: ref_33 article-title: Molecular markers for colon diagnosis, prognosis and targeted therapy publication-title: J. Surg. Oncol. doi: 10.1002/jso.23806 – volume: 88 start-page: 5119 year: 2003 ident: ref_95 article-title: A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells publication-title: J. Clin. Endocrinol. Metab. doi: 10.1210/jc.2003-030222 – volume: 15 start-page: R17 year: 2006 ident: ref_52 article-title: Non-coding RNA publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddl046 – volume: 107 start-page: 246 year: 2015 ident: ref_150 article-title: Cross cancer genomic investigation of inflammation pathway for five common cancers: Lung, ovary, prostate, breast, and colorectal cancer publication-title: J. Natl. Cancer Inst. doi: 10.1093/jnci/djv246 – volume: 66 start-page: 159 year: 2012 ident: ref_264 article-title: Silver sulfadiazine for the treatment of partial-thickness burns and venous stasis ulcers publication-title: J. Am. Acad. Dermatol. doi: 10.1016/j.jaad.2010.06.014 – volume: 22 start-page: 3227 year: 2016 ident: ref_160 article-title: Association of fusobacterium nucleatum infection with colorectal cancer in Chinese patients publication-title: World J. Gastroenterol. doi: 10.3748/wjg.v22.i11.3227 – volume: 4 start-page: 375 year: 2012 ident: ref_286 article-title: New applications of old metal-binding drugs in the treatment of human cancer publication-title: Front. Biosci. doi: 10.2741/s274 – volume: 320 start-page: 1647 year: 2008 ident: ref_129 article-title: Evolution of mammals and their gut microbes publication-title: Science doi: 10.1126/science.1155725 – volume: 66 start-page: 462 year: 2013 ident: ref_145 article-title: Dysbiosis signature of fecal microbiota in colorectal cancer patients publication-title: Microb. Ecol. doi: 10.1007/s00248-013-0245-9 – volume: 4 start-page: 1387 year: 2014 ident: ref_179 article-title: A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner publication-title: Cancer Discov. doi: 10.1158/2159-8290.CD-14-0501 – volume: 30 start-page: 351 year: 2014 ident: ref_243 article-title: A potential role of probiotics in colorectal cancer prevention: Review of possible mechanisms of action publication-title: World J. Microbiol. Biotechnol. doi: 10.1007/s11274-013-1499-6 – volume: 373 start-page: 203 year: 2016 ident: ref_73 article-title: microRNA-187, a downstream effector of TGF-β pathway, suppresses SMAD-mediated epithelial-mesenchymal transition in colorectal cancer publication-title: Cancer Lett. doi: 10.1016/j.canlet.2016.01.037 – volume: 36 start-page: 2675 year: 2015 ident: ref_118 article-title: The expression and clinical significance of microRNAs in colorectal cancer detecting publication-title: Tumor Biol. doi: 10.1007/s13277-014-2890-0 – volume: 107 start-page: 1623 year: 2012 ident: ref_245 article-title: Oral inoculation of probiotics lactobacillus acidophilus NCFM suppresses tumour growth both in segmental orthotopic colon cancer and extra-intestinal tissue publication-title: Br. J. Nutr. doi: 10.1017/S0007114511004934 – volume: 11 start-page: 753 year: 2010 ident: ref_186 article-title: Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis publication-title: Lancet Oncol. doi: 10.1016/S1470-2045(10)70130-3 – volume: 18 start-page: 2938 year: 2000 ident: ref_281 article-title: Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2000.18.16.2938 – volume: 92 start-page: 434 year: 2005 ident: ref_50 article-title: P53 abnormalities and outcomes in colorectal cancer: A systematic review publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6602358 – volume: 111 start-page: 4173 year: 2014 ident: ref_97 article-title: Long–Range interaction and correlation between myc enhancer and oncogenic long noncoding RNA CARLO-5 publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1400350111 – volume: 78 start-page: 48 year: 1996 ident: ref_203 article-title: A new approach to fecal occult blood testing based on the detection of haptoglobin publication-title: Cancer doi: 10.1002/(SICI)1097-0142(19960701)78:1<48::AID-CNCR9>3.0.CO;2-D – volume: 14 start-page: 274 year: 2013 ident: ref_178 article-title: Regulation of the metabolism of polyunsaturated fatty acids and butyrate in colon cancer cells publication-title: Curr. Pharm. Biotechnol. doi: 10.2174/1389201011314030004 – volume: 10 start-page: 683 year: 2015 ident: ref_82 article-title: microRNA-20a enhances the epithelial-to-mesenchymal transition of colorectal cancer cells by modulating matrix metalloproteinases publication-title: Exp. Ther. Med. doi: 10.3892/etm.2015.2538 – volume: 104 start-page: 488 year: 2011 ident: ref_201 article-title: Tumour gene expression predicts response to cetuximab in patients with kras wild-type metastatic colorectal cancer publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6606054 – volume: 26 start-page: 285 year: 2015 ident: ref_234 article-title: Individual non-steroidal anti-inflammatory drugs and risk of acute kidney injury: A systematic review and meta-analysis of observational studies publication-title: Eur. J. Intern. Med. doi: 10.1016/j.ejim.2015.03.008 – volume: 70 start-page: S38 year: 2012 ident: ref_119 article-title: Defining the human microbiome publication-title: Nutr. Rev. doi: 10.1111/j.1753-4887.2012.00493.x – volume: 23 start-page: 283 year: 2016 ident: ref_63 article-title: MicroRNA-92a promotes colorectal cancer cell growth and migration by inhibiting KLF4 publication-title: Oncol. Res. Featur. Preclin. Clin. Cancer Ther. – volume: 39 start-page: 169 year: 2011 ident: ref_93 article-title: Malat-1: A long non-coding RNA and its important 3′ end functional motif in colorectal cancer metastasis publication-title: Int. J. Oncol. – ident: ref_228 – volume: 20 start-page: 908 year: 2014 ident: ref_156 article-title: Inflammation and colorectal cancer, when microbiota-host mutualism breaks publication-title: World J. Gastroenterol. doi: 10.3748/wjg.v20.i4.908 – volume: 85 start-page: 1492 year: 2001 ident: ref_51 article-title: Colorectal cancer genomics: Evidence for multiple genotypes which influence survival publication-title: Br. J. Cancer doi: 10.1054/bjoc.2001.2095 – volume: 375 start-page: 1030 year: 2010 ident: ref_8 article-title: Colorectal cancer publication-title: Lancet doi: 10.1016/S0140-6736(10)60353-4 – volume: 2 start-page: 270 year: 2009 ident: ref_260 article-title: Plant polyphenols as dietary antioxidants in human health and disease publication-title: Oxid. Med. Cell. Longev. doi: 10.4161/oxim.2.5.9498 – ident: ref_4 doi: 10.4018/978-1-4666-6611-5.ch002 – volume: 129 start-page: 2712 year: 2011 ident: ref_244 article-title: Yogurt consumption and risk of colorectal cancer in the italian european prospective investigation into cancer and nutrition cohort publication-title: Int. J. Cancer doi: 10.1002/ijc.26193 – volume: 162 start-page: 54 year: 2014 ident: ref_166 article-title: Fusobacterium and enterobacteriaceae: Important players for CRC? publication-title: Immunol. Lett. doi: 10.1016/j.imlet.2014.05.014 – volume: 257 start-page: 1053 year: 2013 ident: ref_216 article-title: Independent validation of a prognostic genomic signature (coloprint) for patients with stage II colon cancer publication-title: Ann. Surg. doi: 10.1097/SLA.0b013e31827c1180 – volume: 7 start-page: 366 year: 2005 ident: ref_90 article-title: Regulatory sequences of H19 and IGF2 genes in DNA-based therapy of colorectal rat liver metastases publication-title: J. Gene Med. doi: 10.1002/jgm.670 – volume: 487 start-page: 330 year: 2012 ident: ref_31 article-title: Cancer genome atlas network. Comprehensive molecular characterization of human colon and rectal cancer publication-title: Nature doi: 10.1038/nature11252 – volume: 314 start-page: 223 year: 2012 ident: ref_61 article-title: NIRF is frequently upregulated in colorectal cancer and its oncogenicity can be suppressed by LET-7a microRNA publication-title: Cancer Lett. doi: 10.1016/j.canlet.2011.09.033 – volume: 143 start-page: 868 year: 2012 ident: ref_17 article-title: ABC of colorectal cancer publication-title: Gastroenterology doi: 10.1053/j.gastro.2012.07.090 – volume: 102 start-page: 1462 year: 2010 ident: ref_180 article-title: Cancer biomarkers: Can we turn recent failures into success? publication-title: J. Natl. Cancer Inst. doi: 10.1093/jnci/djq306 – volume: 138 start-page: 2059 year: 2010 ident: ref_27 article-title: The chromosomal instability pathway in colon cancer publication-title: Gastroenterology doi: 10.1053/j.gastro.2009.12.065 – volume: 105 start-page: 13421 year: 2008 ident: ref_53 article-title: mir-34a repression of SIRT1 regulates apoptosis publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.0801613105 – volume: 29 start-page: 742 year: 2011 ident: ref_108 article-title: Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression publication-title: Nat. Biotechnol. doi: 10.1038/nbt.1914 – volume: 505 start-page: 559 year: 2014 ident: ref_149 article-title: Diet rapidly and reproducibly alters the human gut microbiome publication-title: Nature doi: 10.1038/nature12820 – volume: 468 start-page: 1 year: 2015 ident: ref_151 article-title: Analysis of the intricate relationship between chronic inflammation and cancer publication-title: Biochem. J. doi: 10.1042/BJ20141337 – volume: 27 start-page: 2128 year: 2008 ident: ref_57 article-title: microRNA-21 (mir-21) post-transcriptionally downregulates tumor suppressor PDCD4 and stimulates invasion, intravasation and metastasis in colorectal cancer publication-title: Oncogene doi: 10.1038/sj.onc.1210856 – ident: ref_36 doi: 10.1186/1471-2407-14-802 – volume: 25 start-page: 2305 year: 2011 ident: ref_105 article-title: A transcribed pseudogene of MYLK promotes cell proliferation publication-title: FASEB J. doi: 10.1096/fj.10-177808 – volume: 19 start-page: 6669 year: 2013 ident: ref_218 article-title: Anticipating the clinical use of prognostic gene expression-based tests for colon cancer stage II and III: Is godot finally arriving? publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-13-1769 – volume: 126 start-page: 1177 year: 2010 ident: ref_211 article-title: A blood-based biomarker panel for stratifying current risk for colorectal cancer publication-title: Int. J. Cancer doi: 10.1002/ijc.24910 – volume: 6 start-page: 24448 year: 2015 ident: ref_66 article-title: miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mtor publication-title: Oncotarget doi: 10.18632/oncotarget.4423 – volume: 55 start-page: 1671 year: 2006 ident: ref_185 article-title: Predictive value of microsatellite instability for benefit from adjuvant fluorouracil chemotherapy in colorectal cancer publication-title: Gut – volume: 7 start-page: 2660 year: 2015 ident: ref_76 article-title: MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1 publication-title: Oncotarget doi: 10.18632/oncotarget.6545 – volume: 37 start-page: 588 year: 2000 ident: ref_192 article-title: The role of hypermethylation of thehmlh1 promoter region in hnpcc versus MSI+ sporadic colorectal cancers publication-title: J. Med. Genet. doi: 10.1136/jmg.37.8.588 – volume: 21 start-page: 93 year: 2010 ident: ref_222 article-title: Advanced colorectal cancer: ESMO clinical practice guidelines for treatment publication-title: Ann. Oncol. doi: 10.1093/annonc/mdq222 – volume: 67 start-page: 685 year: 2015 ident: ref_239 article-title: In-vitro characterisation of a novel celecoxib microbead formulation for the treatment and prevention of colorectal cancer publication-title: J. Pharm. Pharmacol. doi: 10.1111/jphp.12372 – volume: 6 start-page: 215 year: 2013 ident: ref_153 article-title: Microbial dysbiosis and colon carcinogenesis: Could colon cancer be considered a bacteria-related disease? publication-title: Ther. Adv. Gastroenterol. doi: 10.1177/1756283X12473674 – volume: 37 start-page: 2805 year: 2016 ident: ref_162 article-title: Fusobacterium nucleatum, inflammation, and immunity: The fire within human gut publication-title: Tumor Biol. doi: 10.1007/s13277-015-4724-0 – ident: ref_56 doi: 10.1155/2011/792362 – volume: 15 start-page: 95 year: 2014 ident: ref_139 article-title: Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE2 publication-title: Cell Host Microb. doi: 10.1016/j.chom.2013.12.010 – volume: 48 start-page: 526 year: 2001 ident: ref_14 article-title: The risk of colorectal cancer in ulcerative colitis: A meta-analysis publication-title: Gut doi: 10.1136/gut.48.4.526 – volume: 47 start-page: 1467 year: 2004 ident: ref_47 article-title: Association between recurrence of sporadic colorectal cancer, high level of microsatellite instability, and loss of heterozygosity at chromosome 18q publication-title: Dis. Colon Rectum. doi: 10.1007/s10350-004-0628-6 – volume: 12 start-page: 1193 year: 2012 ident: ref_297 article-title: Dithiocarbamate-based coordination compounds as potent proteasome inhibitors in human cancer cells publication-title: Mini Rev. Med. Chem. doi: 10.2174/138955712802762040 – volume: 9 start-page: 288 year: 2015 ident: ref_172 article-title: Red meat and colorectal cancer publication-title: Oncol. Rev. – ident: ref_35 doi: 10.1371/journal.pone.0087456 – volume: 14 start-page: 127 year: 2016 ident: ref_142 article-title: Pathogenic role of the gut microbiota in gastrointestinal diseases publication-title: Intest. Res. doi: 10.5217/ir.2016.14.2.127 – volume: 156 start-page: 264 year: 2014 ident: ref_247 article-title: Effect of probiotics on antioxidant and antimutagenic activities of crude peptide extract from yogurt publication-title: Food Chem. doi: 10.1016/j.foodchem.2014.01.105 – volume: 131 start-page: 1042 year: 2012 ident: ref_59 article-title: MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer publication-title: Int. J. Cancer doi: 10.1002/ijc.26485 – volume: 6 start-page: 5786 year: 2014 ident: ref_141 article-title: Dysbiotic events in gut microbiota: Impact on human health publication-title: Nutrients doi: 10.3390/nu6125786 – volume: 19 start-page: 144 year: 2014 ident: ref_267 article-title: Metal-based anticancer chemotherapeutic agents publication-title: Curr. Opin. Chem. Boil. doi: 10.1016/j.cbpa.2014.02.003 – volume: 486 start-page: 222 year: 2012 ident: ref_126 article-title: Human gut microbiome viewed across age and geography publication-title: Nature doi: 10.1038/nature11053 – volume: 740 start-page: 364 year: 2014 ident: ref_266 article-title: Cisplatin in cancer therapy: Molecular mechanisms of action publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2014.07.025 – volume: 352 start-page: 1071 year: 2005 ident: ref_238 article-title: Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa050405 – ident: ref_164 doi: 10.1093/cid/ciu787 – volume: 293 start-page: 233 year: 2005 ident: ref_19 article-title: Diet and cancer: An evolving picture publication-title: JAMA doi: 10.1001/jama.293.2.233 – volume: 25 start-page: 3230 year: 2007 ident: ref_199 article-title: Expression of epiregulin and amphiregulin and KRAS mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2006.10.5437 – volume: 20 start-page: 1029 year: 2008 ident: ref_106 article-title: The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1 publication-title: Oncol. Rep. – volume: 96 start-page: 261 year: 2004 ident: ref_11 article-title: Revised bethesda guidelines for hereditary nonpolyposis colorectal cancer (lynch syndrome) and microsatellite instability publication-title: J. Natl. Cancer Inst. doi: 10.1093/jnci/djh034 – volume: 97 start-page: 1147 year: 2006 ident: ref_103 article-title: Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KVDMR1 in colorectal cancers publication-title: Cancer Sci. doi: 10.1111/j.1349-7006.2006.00305.x – volume: 9 start-page: 2125 year: 2007 ident: ref_123 article-title: Diversity of the human gastrointestinal tract microbiota revisited publication-title: Environ. Microbial. doi: 10.1111/j.1462-2920.2007.01369.x – volume: 300 start-page: 2765 year: 2008 ident: ref_23 article-title: Smoking and colorectal cancer: A meta-analysis publication-title: JAMA doi: 10.1001/jama.2008.839 – volume: 21 start-page: 167 year: 2013 ident: ref_124 article-title: Development of intestinal microbiota in infants and its impact on health publication-title: Trends Microbial. doi: 10.1016/j.tim.2012.12.001 – ident: ref_44 doi: 10.1371/journal.pone.0065479 – ident: ref_75 doi: 10.3892/mmr.2016.4788 – ident: ref_229 doi: 10.1200/jco.2013.31.15_suppl.e14517 – volume: 49 start-page: 4364 year: 2013 ident: ref_285 article-title: A gold (III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells publication-title: Chem. Commun. doi: 10.1039/C2CC37366A – ident: ref_293 doi: 10.1371/journal.pone.0124487 – volume: 66 start-page: 53 year: 2012 ident: ref_148 article-title: A vegan or vegetarian diet substantially alters the human colonic faecal microbiota publication-title: Eur. J. Clin. Nutr. doi: 10.1038/ejcn.2011.141 – volume: 38 start-page: 583 year: 2015 ident: ref_152 article-title: An analysis of genetic factors related to risk of inflammatory bowel disease and colon cancer publication-title: Cancer Epidemiol. doi: 10.1016/j.canep.2014.07.003 – volume: 21 start-page: 1220 year: 2014 ident: ref_283 article-title: Metal-N-heterocyclic carbene complexes as anti-tumor agents publication-title: Curr. Med. Chem. doi: 10.2174/0929867321666131217161849 – volume: 49 start-page: 583 year: 2002 ident: ref_272 article-title: Recognition and repair of DNA-cisplatin adducts publication-title: Acta Biochim. Pol. doi: 10.18388/abp.2002_3768 – volume: 62 start-page: 1107 year: 2013 ident: ref_241 article-title: Probiotics in colorectal cancer (CRC) with emphasis on mechanisms of action and current perspectives publication-title: J. Med. Microbial. doi: 10.1099/jmm.0.048975-0 – volume: 130 start-page: 32 year: 2014 ident: ref_290 article-title: Strong inhibition of thioredoxin reductase by highly cytotoxic gold (I) complexes. DNA binding studies publication-title: J. Inorg. Biochem. doi: 10.1016/j.jinorgbio.2013.09.019 – volume: 23 start-page: 1097 year: 2006 ident: ref_15 article-title: Meta-analysis: Colorectal and small bowel cancer risk in patients with crohn’s disease publication-title: Aliment. Pharmacol. Therap. doi: 10.1111/j.1365-2036.2006.02854.x – volume: 27 start-page: 378 year: 1984 ident: ref_287 article-title: Auranofin publication-title: Drugs doi: 10.2165/00003495-198427050-00002 – volume: 18 start-page: 1888 year: 2009 ident: ref_197 article-title: Fecal cyclooxygenase 2 plus matrix metalloproteinase 7 mRNA assays as a marker for colorectal cancer screening publication-title: Cancer Epidemiol. Biomark. Prev. doi: 10.1158/1055-9965.EPI-08-0937 – volume: 23 start-page: 1377 year: 2004 ident: ref_210 article-title: Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters publication-title: Oncogene doi: 10.1038/sj.onc.1207262 – volume: 61 start-page: 759 year: 1990 ident: ref_9 article-title: A genetic model for colorectal tumorigenesis publication-title: Cell doi: 10.1016/0092-8674(90)90186-I – volume: 61 start-page: 1 year: 2016 ident: ref_74 article-title: ORAI1, a direct target of microRNA-519, promotes progression of colorectal cancer via AKT/GSK3Β signaling pathway publication-title: Digest. Dis. Sci. doi: 10.1007/s10620-015-4029-6 – volume: 816 start-page: 25 year: 2014 ident: ref_230 article-title: The role of inflammation in colon cancer publication-title: Adv. Exp. Med. Biol. doi: 10.1007/978-3-0348-0837-8_2 – volume: 348 start-page: 919 year: 2003 ident: ref_10 article-title: Hereditary colorectal cancer publication-title: N. Engl. J. Med. doi: 10.1056/NEJMra012242 – volume: 2 start-page: 496 year: 2013 ident: ref_46 article-title: PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival publication-title: Cancer Med. doi: 10.1002/cam4.97 – volume: 31 start-page: 350 year: 2010 ident: ref_88 article-title: Oncofetal H19-derived mir-675 regulates tumor suppressor RB in human colorectal cancer publication-title: Carcinogenesis doi: 10.1093/carcin/bgp181 – volume: 237 start-page: 219 year: 2015 ident: ref_274 article-title: An integrated view of cisplatin-induced nephrotoxicity and ototoxicity publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2015.06.012 – volume: 11 start-page: 521 year: 2011 ident: ref_269 article-title: Transition metal based anticancer drugs publication-title: Curr. Top. Med. Chem. doi: 10.2174/156802611794785226 – volume: 1 start-page: 7 year: 2013 ident: ref_187 article-title: The relevance of BRAF and extended ras mutational analyses for metastatic colorectal cancer patients publication-title: OA Mol. Oncol. – volume: 8 start-page: 686 year: 2011 ident: ref_29 article-title: Epigenetics and colorectal cancer publication-title: Nat. Rev. Gastroenterol. Hepatol. doi: 10.1038/nrgastro.2011.173 – volume: 102 start-page: 803 year: 2007 ident: ref_202 article-title: Diagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy publication-title: Am. J. Gastroenterol. doi: 10.1111/j.1572-0241.2007.01126.x – volume: 48 start-page: 1977 year: 2016 ident: ref_70 article-title: Epigenetic silencing of mir-181b contributes to tumorigenicity in colorectal cancer by targeting RASSF1A publication-title: Int. J. Oncol. doi: 10.3892/ijo.2016.3414 – volume: 32 start-page: 1207 year: 2011 ident: ref_58 article-title: MicroRNA 345, a methylation-sensitive microrna is involved in cell proliferation and invasion in human colorectal cancer publication-title: Carcinogenesis doi: 10.1093/carcin/bgr114 – volume: 10 start-page: 1 year: 2011 ident: ref_87 article-title: The functional role of long non-coding RNA in human carcinomas publication-title: Mol. Cancer doi: 10.1186/1476-4598-10-38 – volume: 39 start-page: 1 year: 2016 ident: ref_140 article-title: Eubiosis and dysbiosis: The two sides of the microbiota publication-title: New Microbial. – volume: 110 start-page: 164 year: 2014 ident: ref_116 article-title: Amplification of PVT1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers publication-title: Br. J. Cancer doi: 10.1038/bjc.2013.698 – volume: 60 start-page: 3823 year: 2000 ident: ref_259 article-title: Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells publication-title: Cancer Res. – volume: 38 start-page: 787 year: 2006 ident: ref_30 article-title: CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer publication-title: Nat. Genet. doi: 10.1038/ng1834 – volume: 71 start-page: 725 year: 2011 ident: ref_227 article-title: Hydrophilic agarose macrobead cultures select for outgrowth of carcinoma cell populations that can restrict tumor growth publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-10-2258 – volume: 21 start-page: 275 year: 2016 ident: ref_291 article-title: Novel antitumor adamantane-azole gold (I) complexes as potential inhibitors of thioredoxin reductase publication-title: J. Biol. Inorg. Chem. doi: 10.1007/s00775-016-1338-y – volume: 32 start-page: 3710 year: 2013 ident: ref_299 article-title: S-propargylthiopyridine phosphane derivatives as anticancer agents: Characterization and antitumor activity publication-title: Organometallics doi: 10.1021/om400340a – volume: 14 start-page: 21 year: 2016 ident: ref_18 article-title: Obesity and colorectal cancer: Molecular features of adipose tissue publication-title: J. Transl. Med. doi: 10.1186/s12967-016-0772-5 – volume: 47 start-page: 1073 year: 2002 ident: ref_188 article-title: KRAS mutations in sporadic colorectal tumors in Israel: Unusual high frequency of codon 13 mutations and evidence for nonhomogeneous representation of mutation subtypes publication-title: Dig. Dis. Sci. doi: 10.1023/A:1015090124153 – volume: 31 start-page: 4512 year: 2013 ident: ref_213 article-title: Validation of the 12-gene colon cancer recurrence score in NSABP C-07 as a predictor of recurrence in patients with stage II and III colon cancer treated with fluorouracil and leucovorin (FU/LV) and FU/LV plus oxaliplatin publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2012.47.3116 – volume: 10 start-page: 93 year: 2013 ident: ref_117 article-title: Diagnostic microRNA markers to screen for sporadic human colon cancer in stool: I. Proof of principle publication-title: Cancer Genom. Proteom. – volume: 26 start-page: 5668 year: 2008 ident: ref_190 article-title: Using predictive biomarkers to select patients with advanced colorectal cancer for treatment with epidermal growth factor receptor antibodies publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2008.19.5024 – volume: 5 start-page: 845 year: 2005 ident: ref_181 article-title: Biomarkers in cancer staging, prognosis and treatment selection publication-title: Nat. Rev. Cancer doi: 10.1038/nrc1739 – volume: 6 start-page: 290 year: 2015 ident: ref_34 article-title: Regulation of myc gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer publication-title: World J. Biol. Chem. doi: 10.4331/wjbc.v6.i4.290 – volume: 19 start-page: 398 year: 2015 ident: ref_284 article-title: Synthesis and anti-cancer activities of a water soluble gold (III) porphyrin publication-title: J. Porphyr. Phthalocyanines doi: 10.1142/S1088424615500236 – volume: 4 start-page: 1895 year: 2011 ident: ref_233 article-title: Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats publication-title: Cancer Prev. Res. doi: 10.1158/1940-6207.CAPR-11-0222 – volume: 70 start-page: 229 year: 2016 ident: ref_254 article-title: Microcapsules containing astaxanthin from shrimp waste as potential food coloring and functional ingredient: Characterization, stability, and bioaccessibility publication-title: LWT Food Sci. Technol. doi: 10.1016/j.lwt.2016.02.040 – volume: 58 start-page: 90 year: 2009 ident: ref_38 article-title: CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer publication-title: Gut doi: 10.1136/gut.2008.155473 – volume: 12 start-page: 1059 year: 2014 ident: ref_12 article-title: Familial colorectal cancer, beyond lynch syndrome publication-title: Clin. Gastroenterol. Hepatol. doi: 10.1016/j.cgh.2013.08.015 – volume: 90 start-page: 221 year: 2016 ident: ref_68 article-title: miRNA-503 promotes tumor progression and is associated with early recurrence and poor prognosis in human colorectal cancer publication-title: Oncology doi: 10.1159/000444493 – volume: 42 start-page: 452 year: 2006 ident: ref_246 article-title: Effects of lactobacillus strains on cancer cell proliferation and oxidative stress in vitro publication-title: Lett. Appl. Microbial. doi: 10.1111/j.1472-765X.2006.01913.x – volume: 11 start-page: 6738 year: 2005 ident: ref_240 article-title: Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-05-0171 – volume: 53 start-page: 88 year: 2014 ident: ref_102 article-title: Reciprocal regulation of HIF-1α and lincRNA-p21 modulates the Warburg effect publication-title: Mol. Cell doi: 10.1016/j.molcel.2013.11.004 – volume: 41 start-page: 4976 year: 2013 ident: ref_100 article-title: LncRNA loc285194 is a p53-regulated tumor suppressor publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkt182 – volume: 39 start-page: 8113 year: 2010 ident: ref_271 article-title: The status of platinum anticancer drugs in the clinic and in clinical trials publication-title: Dalton Trans. doi: 10.1039/c0dt00292e – volume: 39 start-page: 146 year: 2011 ident: ref_2 article-title: LncRNAdb: A reference database for long noncoding RNAs publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkq1138 – volume: 72 start-page: 1171 year: 1993 ident: ref_231 article-title: Aspirin use, cancer, and polyps of the large bowel publication-title: Cancer doi: 10.1002/1097-0142(19930815)72:4<1171::AID-CNCR2820720407>3.0.CO;2-D – volume: 23 start-page: 1446 year: 2013 ident: ref_98 article-title: CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer publication-title: Genome Res. doi: 10.1101/gr.152942.112 – ident: ref_175 doi: 10.1038/ncomms7528 – ident: ref_176 doi: 10.1038/ncomms7342 – volume: 13 start-page: 11 year: 2009 ident: ref_221 article-title: Previstage (TM) GCC colorectal cancer staging test: A new molecular test to identify lymph node metastases and provide more accurate information about the stage of patients with colorectal cancer publication-title: Mol. Diagn. Ther. doi: 10.1007/BF03256309 – volume: 72 start-page: 4287 year: 2015 ident: ref_133 article-title: From cultured to uncultured genome sequences: Metagenomics and modeling microbial ecosystems publication-title: Cell. Mol. Life Sci. doi: 10.1007/s00018-015-2004-1 – volume: 79 start-page: 164 year: 2014 ident: ref_300 article-title: Gold (I) complexes with alkylated PTA (1,3,5-triaza-7-phosphaadamantane) phosphanes as anticancer metallodrugs publication-title: Eur. J. Med. Chem. doi: 10.1016/j.ejmech.2014.04.001 – volume: 118 start-page: 5234 year: 2012 ident: ref_219 article-title: Generation and external validation of a tumor-derived 5-gene prognostic signature for recurrence of lymph node-negative, invasive colorectal carcinoma publication-title: Cancer doi: 10.1002/cncr.27628 – volume: 29 start-page: 1 year: 2010 ident: ref_212 article-title: A case-controlled validation study of a blood-based seven-gene biomarker panel for colorectal cancer in Malaysia publication-title: J. Exp. Clin. Cancer Res. doi: 10.1186/1756-9966-29-128 – volume: 465 start-page: 1033 year: 2010 ident: ref_104 article-title: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology publication-title: Nature doi: 10.1038/nature09144 – volume: 22 start-page: 7265 year: 2003 ident: ref_277 article-title: Cisplatin: Mode of cytotoxic action and molecular basis of resistance publication-title: Oncogene doi: 10.1038/sj.onc.1206933 – volume: 14 start-page: 207 year: 2014 ident: ref_159 article-title: Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment publication-title: Cell Host Microb. doi: 10.1016/j.chom.2013.07.007 – volume: 19 start-page: 935 year: 2008 ident: ref_207 article-title: Circulating tumor cells in colorectal cancer: Correlation with clinical and pathological variables publication-title: Ann. Oncol. doi: 10.1093/annonc/mdm583 – volume: 207 start-page: 51 year: 2016 ident: ref_253 article-title: Basil as functional and preserving ingredient in “serra da estrela” cheese publication-title: Food Chem. doi: 10.1016/j.foodchem.2016.03.085 – ident: ref_255 – volume: 4 start-page: e00692-13 year: 2013 ident: ref_157 article-title: The gut microbiome modulates colon tumorigenesis publication-title: MBio doi: 10.1128/mBio.00692-13 – volume: 18 start-page: 820 year: 2015 ident: ref_261 article-title: Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects—A review publication-title: J. Funct. Foods doi: 10.1016/j.jff.2015.06.018 – volume: 60 start-page: 131 year: 2008 ident: ref_21 article-title: Processed meat and colorectal cancer: A review of epidemiologic and experimental evidence publication-title: Nutr. Cancer doi: 10.1080/01635580701684872 – volume: 12 start-page: 219 year: 2012 ident: ref_268 article-title: Next-generation anticancer metallodrugs publication-title: Curr. Top. Med. Chem. doi: 10.2174/156802612799078964 – ident: ref_169 – volume: 21 start-page: 1275 year: 2015 ident: ref_40 article-title: Prognostic value of KRAS and BRAF mutations in curatively resected colorectal cancer publication-title: World J. Gastroenterol. WJG doi: 10.3748/wjg.v21.i4.1275 – volume: 27 start-page: 627 year: 2007 ident: ref_49 article-title: Relationship between chromosome 18q status and colorectal cancer prognosis: A prospective, blinded analysis of 280 patients publication-title: Anticancer Res. – volume: 30 start-page: 1 year: 2013 ident: ref_110 article-title: Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis in patients with colorectal cancer publication-title: Med. Oncol. doi: 10.1007/s12032-013-0588-6 – volume: 8 start-page: 156 year: 2002 ident: ref_206 article-title: Total levels of tissue inhibitor of metalloproteinases 1 in plasma yield high diagnostic sensitivity and specificity in patients with colon cancer publication-title: Clin. Cancer Res. – volume: 22 start-page: 1564 year: 2004 ident: ref_196 article-title: Gene expression profiles and molecular markers to predict recurrence of dukes’ B colon cancer publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2004.08.186 – volume: 4 start-page: 307 year: 2005 ident: ref_279 article-title: Cellular processing of platinum anticancer drugs publication-title: Nat. Rev. Drug Discov. doi: 10.1038/nrd1691 – ident: ref_273 doi: 10.1098/rsta.2014.0185 – volume: 2015 start-page: 1 year: 2015 ident: ref_193 article-title: Colorectal cancer biomarkers: Where are we now? publication-title: BioMed Res. Int. – volume: 13 start-page: 273 year: 2016 ident: ref_78 article-title: microRNA-1246 promotes growth and metastasis of colorectal cancer cells involving CCNG2 reduction publication-title: Mol. Med. Rep. doi: 10.3892/mmr.2015.4557 – volume: 135 start-page: 1269 year: 2011 ident: ref_184 article-title: Microsatellite instability and colorectal cancer publication-title: Arch. Pathol. Lab. Med. doi: 10.5858/arpa.2011-0035-RA – ident: ref_92 doi: 10.1371/journal.pgen.1002071 – volume: 19 start-page: 492 year: 2014 ident: ref_214 article-title: Prospective multicenter study of the impact of oncotype DX colon cancer assay results on treatment recommendations in stage II colon cancer patients publication-title: Oncologist doi: 10.1634/theoncologist.2013-0401 – volume: 48 start-page: 158 year: 2012 ident: ref_250 article-title: Physiological roles of mitochondrial reactive oxygen species publication-title: Mol. Cell doi: 10.1016/j.molcel.2012.09.025 – volume: 19 start-page: 1266 year: 2013 ident: ref_294 article-title: The thioredoxin system as a therapeutic target in human health and disease publication-title: Antioxid. Redox signal. doi: 10.1089/ars.2012.4757 – volume: 113 start-page: S1 year: 2015 ident: ref_128 article-title: Dietary effects on human gut microbiome diversity publication-title: Br. J. Nutr. doi: 10.1017/S0007114514004127 – volume: 58 start-page: 1064 year: 2005 ident: ref_89 article-title: H19 expression in hepatic metastases from a range of human carcinomas publication-title: J. Clin. Pathol. doi: 10.1136/jcp.2004.023648 – volume: 124 start-page: 4166 year: 2014 ident: ref_163 article-title: Bacteroides fragilis subverts mucosal biology: From symbiont to colon carcinogenesis publication-title: J. Clin. Investing. doi: 10.1172/JCI72334 – volume: 58 start-page: 130 year: 2008 ident: ref_13 article-title: Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: A joint guideline from the American cancer society, the US multi-society task force on colorectal cancer, and the American college of radiology publication-title: CA Cancer J. Clin. doi: 10.3322/CA.2007.0018 – volume: 24 start-page: 102 year: 2013 ident: ref_143 article-title: The microbiota and inflammatory bowel disease: Insights from animal models publication-title: Anaerobe doi: 10.1016/j.anaerobe.2013.04.006 – volume: 36 start-page: 137 year: 2015 ident: ref_136 article-title: Pathways and functions of gut microbiota metabolism impacting host physiology publication-title: Curr. Opin. Biotechnol. doi: 10.1016/j.copbio.2015.08.015 – volume: 11 start-page: 93 year: 2012 ident: ref_280 article-title: Literature review and practical aspects on the management of oxaliplatin-associated toxicity publication-title: Clin. Colorectal Cancer doi: 10.1016/j.clcc.2011.10.004 – ident: ref_130 doi: 10.1371/journal.pone.0090731 – volume: 15 start-page: 773 year: 2015 ident: ref_301 article-title: In vivo anticancer activity, toxicology and histopathological studies of the thiolate gold (I) complex [Au(Spyrimidine)(PTA-CH2Ph)]Br publication-title: Anti-Cancer Agents Med. Chem. doi: 10.2174/1871520615666150129211440 – volume: 49 start-page: 69 year: 2016 ident: ref_71 article-title: microRNA-497 inhibits invasion and metastasis of colorectal cancer cells by targeting vascular endothelial growth factor-A publication-title: Cell Prolif. doi: 10.1111/cpr.12237 – volume: 32 start-page: 1 year: 2013 ident: ref_112 article-title: Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer publication-title: J. Exp. Clin. Cancer Res. doi: 10.1186/1756-9966-32-104 – volume: 37 start-page: 223 year: 2015 ident: ref_127 article-title: The gastrointestinal microbiome: Alcohol effects on the composition of intestinal microbiota publication-title: Alcohol Res. Curr. Rev. – volume: 18 start-page: 2257 year: 2012 ident: ref_45 article-title: Prognostic role of PIK3CA mutation in colorectal cancer: Cohort study and literature review publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-11-2410 – ident: ref_65 doi: 10.18632/oncotarget.8937 – volume: 18 start-page: 587 year: 2008 ident: ref_32 article-title: APC shuttling to the membrane, nucleus and beyond publication-title: Trends Cell Boil. doi: 10.1016/j.tcb.2008.09.002 – volume: 47 start-page: 1007 year: 2011 ident: ref_121 article-title: The human gut microbiota and virome: Potential therapeutic implications publication-title: Dig. Liver Dis. doi: 10.1016/j.dld.2015.07.008 – volume: 37 start-page: 299 year: 2016 ident: ref_72 article-title: Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of gastric cancer publication-title: Tumor Biol. doi: 10.1007/s13277-015-3750-2 – volume: 16 start-page: 1 year: 2014 ident: ref_138 article-title: Far from the eyes, close to the heart: Dysbiosis of gut microbiota and cardiovascular consequences publication-title: Curr. Cardiol. Rep. doi: 10.1007/s11886-014-0540-1 – volume: 25 start-page: 1032 year: 2014 ident: ref_39 article-title: Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H) publication-title: Ann. Oncol. doi: 10.1093/annonc/mdu100 – ident: ref_69 doi: 10.1200/jco.2015.33.15_suppl.e22006 – volume: 46 start-page: 4113 year: 1998 ident: ref_257 article-title: Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products publication-title: J. Agric. Food chem. doi: 10.1021/jf9801973 – volume: 54 start-page: 742 year: 2015 ident: ref_114 article-title: Down-regulation of NCRAN, a long non-coding RNA, contributes to colorectal cancer cell migration and invasion and predicts poor overall survival for colorectal cancer patients publication-title: Mol. Carcinog. doi: 10.1002/mc.22137 – volume: 49 start-page: 1083 year: 2013 ident: ref_113 article-title: Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis publication-title: Mol. Cell doi: 10.1016/j.molcel.2013.01.010 – volume: 512 start-page: 82 year: 2014 ident: ref_115 article-title: PVT1 dependence in cancer with myc copy-number increase publication-title: Nature doi: 10.1038/nature13311 – ident: ref_220 – volume: 6 start-page: 680 year: 2015 ident: ref_80 article-title: microRNA-638 inhibits cell proliferation by targeting phospholipase D1 in human gastric carcinoma publication-title: Protein Cell doi: 10.1007/s13238-015-0187-8 – volume: 58 start-page: 6277 year: 2010 ident: ref_251 article-title: Studies on chemical constituents and bioactivity of rosa micrantha: An alternative antioxidants source for food, pharmaceutical, or cosmetic applications publication-title: J. Agric. Food Chem. doi: 10.1021/jf101394w – volume: 226 start-page: 544 year: 2012 ident: ref_60 article-title: LET-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer publication-title: J. Pathol. doi: 10.1002/path.3014 – volume: 45 start-page: 2462 year: 2016 ident: ref_302 article-title: In vitro and in vivo evaluation of organometallic gold (I) derivatives as anticancer agents publication-title: Dalton Trans. doi: 10.1039/C5DT01802A – ident: ref_6 – volume: 5 start-page: 1 year: 2014 ident: ref_223 article-title: Metastatic colorectal cancer: Esmo clinical practice guidelines for diagnosis, treatment and follow-up publication-title: Ann. Oncol. – volume: 138 start-page: 2073 year: 2010 ident: ref_28 article-title: Microsatellite instability in colorectal cancer publication-title: Gastroenterology doi: 10.1053/j.gastro.2009.12.064 – volume: 9 start-page: 64 year: 2015 ident: ref_182 article-title: Biomarkers of colorectal cancer: Recent advances and future challenges publication-title: Proteom. Clin. Appl. doi: 10.1002/prca.201400082 – volume: 10 start-page: 250 year: 2005 ident: ref_224 article-title: Critical evaluation of current treatments in metastatic colorectal cancer publication-title: Oncologist doi: 10.1634/theoncologist.10-4-250 – volume: 139 start-page: 437 year: 2013 ident: ref_96 article-title: Long noncoding RNA CCAT1, which could be activated by c-myc, promotes the progression of gastric carcinoma publication-title: J. Cancer Res. Clin. Oncol. doi: 10.1007/s00432-012-1324-x – volume: 22 start-page: 557 year: 2016 ident: ref_158 article-title: Association of fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer publication-title: World J. Gastroenterol. doi: 10.3748/wjg.v22.i2.557 – volume: 124 start-page: 2406 year: 2009 ident: ref_25 article-title: Cigarette smoking and colorectal cancer incidence and mortality: Systematic review and meta-analysis publication-title: Int. J. Cancer doi: 10.1002/ijc.24191 – volume: 4 start-page: 127 year: 2012 ident: ref_85 article-title: natures: Versatile master regulators of gene expression and crucial players in cancer publication-title: Am. J. Transl. Res. – volume: 284 start-page: 1247 year: 2000 ident: ref_237 article-title: Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The class study: A randomized controlled trial publication-title: JAMA doi: 10.1001/jama.284.10.1247 – ident: ref_215 doi: 10.1200/JCO.2010.30.1077 – volume: 69 start-page: 1851 year: 2009 ident: ref_191 article-title: PIK3CA mutations in colorectal cancer are associated with clinical resistance to egfr-targeted monoclonal antibodies publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-08-2466 – volume: 29 start-page: 638 year: 2013 ident: ref_3 article-title: miRCancer: A microRNA-cancer association database constructed by text mining on literature publication-title: Bioinformatics doi: 10.1093/bioinformatics/btt014 – volume: 15 start-page: 2120 year: 2008 ident: ref_209 article-title: Persistent presence of postoperative circulating tumor cells is a poor prognostic factor for patients with stage I–III colorectal cancer after curative resection publication-title: Ann. Surg. Oncol. doi: 10.1245/s10434-008-9961-7 – ident: ref_256 – volume: 38 start-page: 276 year: 2015 ident: ref_131 article-title: The human gut microbiome, a taxonomic conundrum publication-title: Syst. Appl. Microbial. doi: 10.1016/j.syapm.2015.03.004 – volume: 51 start-page: 2 year: 1991 ident: ref_225 article-title: The inhibition of tumor growth by tumor mass publication-title: Cancer Res. – volume: 102 start-page: 245 year: 2011 ident: ref_111 article-title: Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility publication-title: Cancer Sci. doi: 10.1111/j.1349-7006.2010.01737.x – volume: 19 start-page: 1766 year: 2010 ident: ref_198 article-title: Fecal microRNAs as novel biomarkers for colon cancer screening publication-title: Cancer Epidemiol. Biomark. Prev. doi: 10.1158/1055-9965.EPI-10-0027 – volume: 66 start-page: 83 year: 2015 ident: ref_282 article-title: Recent therapeutic advances in the treatment of colorectal cancer publication-title: Ann. Rev. Med. doi: 10.1146/annurev-med-051513-102539 – volume: 5 start-page: 411 year: 2014 ident: ref_134 article-title: The interplay between the gut microbiota and the immune system publication-title: Gut Microb. doi: 10.4161/gmic.29330 – volume: 16 start-page: 1813 year: 2010 ident: ref_270 article-title: Novel metals and metal complexes as platforms for cancer therapy publication-title: Curr. Pharm. Des. doi: 10.2174/138161210791209009 – volume: 108 start-page: 820 year: 2012 ident: ref_177 article-title: A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate publication-title: Br. J. Nutr. doi: 10.1017/S0007114512001948 – ident: ref_5 – volume: 21 start-page: 139 year: 2005 ident: ref_258 article-title: Extraction of polyphenolics from plant material for functional foods—Engineering and technology publication-title: Food Rev. Int. doi: 10.1081/FRI-200040606 – volume: 521 start-page: S1 year: 2015 ident: ref_7 article-title: Colorectal cancer publication-title: Nature doi: 10.1038/521S1a – volume: 21 start-page: 1313 year: 2015 ident: ref_42 article-title: Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-14-2779 – volume: 21 start-page: 688 year: 2009 ident: ref_94 article-title: Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis publication-title: Eur. J. Gastroenterol. Hepatol. doi: 10.1097/MEG.0b013e328306a3a2 – volume: 16 start-page: 7493 year: 2015 ident: ref_137 article-title: Impacts of gut bacteria on human health and diseases publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms16047493 – ident: ref_165 doi: 10.1186/s12879-014-0733-7 – volume: 98 start-page: 111 year: 2013 ident: ref_174 article-title: Diet, microbiota, and microbial metabolites in colon cancer risk in rural africans and African americans publication-title: Am. J. Clin. Nutr. doi: 10.3945/ajcn.112.056689 – volume: 16 start-page: 1 year: 2014 ident: ref_146 article-title: Cancer-promoting effects of microbial dysbiosis publication-title: Curr. Oncol. Rep. doi: 10.1007/s11912-014-0406-0 – volume: 135 start-page: 1079 year: 2008 ident: ref_26 article-title: Genomic and epigenetic instability in colorectal cancer pathogenesis publication-title: Gastroenterology doi: 10.1053/j.gastro.2008.07.076 – volume: 42 start-page: 872 year: 2007 ident: ref_289 article-title: Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells publication-title: Free Rad. Biol. Med. doi: 10.1016/j.freeradbiomed.2006.12.021 – ident: ref_262 doi: 10.1371/journal.pone.0159136 – volume: 133 start-page: 55 year: 2002 ident: ref_101 article-title: Cloning of the mRNA of overexpression in colon carcinoma-1: A sequence overexpressed in a subset of colon carcinomas publication-title: Cancer Genet. Cytogenet. doi: 10.1016/S0165-4608(01)00634-3 – volume: 24 start-page: 435 year: 2015 ident: ref_77 article-title: Exosome-carried microRNA-375 inhibits cell progression and dissemination via Bcl-2 blocking in colon cancer publication-title: J. Gastrointest. Liver Dis. doi: 10.15403/jgld.2014.1121.244.375 – volume: 99 start-page: 173 year: 2015 ident: ref_54 article-title: MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer publication-title: Exp. Mol. Pathol. doi: 10.1016/j.yexmp.2015.06.014 – volume: 20 start-page: 859 year: 2014 ident: ref_167 article-title: Colonization of the human gut by E. Coli and colorectal cancer risk publication-title: Clin. Cancer Res. doi: 10.1158/1078-0432.CCR-13-1343 – volume: 33 start-page: 983 year: 2013 ident: ref_173 article-title: Review of the association between meat consumption and risk of colorectal cancer publication-title: Nutr. Res. doi: 10.1016/j.nutres.2013.07.018 – volume: 24 start-page: 4685 year: 2006 ident: ref_195 article-title: Stage II colon cancer prognosis prediction by tumor gene expression profiling publication-title: J. Clin. Oncol. doi: 10.1200/JCO.2005.05.0229 – volume: 115 start-page: 952 year: 1991 ident: ref_232 article-title: Effects of long-term sulindac therapy on colonic polyposis publication-title: Ann. Intern. Med. doi: 10.7326/0003-4819-115-12-952 – volume: 233 start-page: 810 year: 2008 ident: ref_263 article-title: Mercury in traditional medicines: Is cinnabar toxicologically similar to common mercurials? publication-title: Exp. Boil. Med. doi: 10.3181/0712-MR-336 – volume: 32 start-page: 1798 year: 2011 ident: ref_62 article-title: microRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4 publication-title: Carcinogenesis doi: 10.1093/carcin/bgr213 – volume: 6 start-page: 20785 year: 2015 ident: ref_43 article-title: Similar but different: Distinct roles for KRAS and BRAF oncogenes in colorectal cancer development and therapy resistance publication-title: Oncotarget doi: 10.18632/oncotarget.4750 – volume: 20 start-page: 7878 year: 2014 ident: ref_242 article-title: Emerging roles of lactic acid bacteria in protection against colorectal cancer publication-title: World J. Gastroenterol. doi: 10.3748/wjg.v20.i24.7878 – volume: 2 start-page: 829 year: 2011 ident: ref_99 article-title: Colorectal neoplasia differentially expressed (CRNDE), a novel gene with elevated expression in colorectal adenomas and adenocarcinomas publication-title: Gene Cancer doi: 10.1177/1947601911431081 – volume: 4 start-page: 177 year: 2011 ident: ref_20 article-title: Heme iron from meat and risk of colorectal cancer: A meta-analysis and a review of the mechanisms involved publication-title: Cancer Prev. Res. doi: 10.1158/1940-6207.CAPR-10-0113 – volume: 22 start-page: 455 year: 2010 ident: ref_135 article-title: Microbiota-stimulated immune mechanisms to maintain gut homeostasis publication-title: Curr. Opin. Immunol. doi: 10.1016/j.coi.2010.06.008 – volume: 20 start-page: 1223 year: 2009 ident: ref_208 article-title: Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer publication-title: Ann. Oncol. doi: 10.1093/annonc/mdn786 – volume: 43 start-page: 168 year: 2014 ident: ref_1 article-title: LncRNAdb v2. 0: Expanding the reference database for functional long noncoding RNAs publication-title: Nucleic Acids Res. doi: 10.1093/nar/gku988 – volume: 11 start-page: 183 year: 2016 ident: ref_265 article-title: Effects of a combination of puerarin, baicalin and berberine on the expression of proliferator-activated receptor-γ and insulin receptor in a rat model of nonalcoholic fatty liver disease publication-title: Exp. Ther. Med. doi: 10.3892/etm.2015.2846 – volume: 10 start-page: 99 year: 2015 ident: ref_41 article-title: A mutant BRAF V600E-specific immunohistochemical assay: Correlation with molecular mutation status and clinical outcome in colorectal cancer publication-title: Target. Oncol. doi: 10.1007/s11523-014-0319-8 – volume: 544 start-page: 305 year: 2003 ident: ref_170 article-title: Environment and cancer in Brazil: An overview from a public health perspective publication-title: Rev. Mutat. Res. doi: 10.1016/j.mrrev.2003.07.005 – volume: 15 start-page: 423 year: 2014 ident: ref_84 article-title: The rise of regulatory RNA publication-title: Nat. Rev. Genet. doi: 10.1038/nrg3722 – volume: 109 start-page: 162 year: 2010 ident: ref_298 article-title: Inhibition of tumor proteasome activity by gold-dithiocarbamato complexes via both redox-dependent and-independent processes publication-title: J. Cell. Biochem. doi: 10.1002/jcb.22394 – volume: 102 start-page: 735 year: 2008 ident: ref_204 article-title: Haptoglobin, inflammation and disease publication-title: Trans. R. Soc. Trop. Med. Hyg. doi: 10.1016/j.trstmh.2008.04.010 – volume: 137 start-page: 2310 year: 2015 ident: ref_83 article-title: microRNA-409-3p suppresses colorectal cancer invasion and metastasis partly by targeting GAB1 expression publication-title: Int. J. Cancer doi: 10.1002/ijc.29607 – volume: 39 start-page: 155 year: 2004 ident: ref_22 article-title: Alcohol and cancer publication-title: Alcohol Alcoholism doi: 10.1093/alcalc/agh057 – volume: 2 start-page: 794 year: 2015 ident: ref_86 article-title: The interplay of long non-coding RNAs and myc in cancer publication-title: AIMS Biophys. doi: 10.3934/biophy.2015.4.794 – volume: 16 start-page: 1935 year: 2007 ident: ref_205 article-title: Blood markers for early detection of colorectal cancer: A systematic review publication-title: Cancer Epidemiol. Biomark. Prev. doi: 10.1158/1055-9965.EPI-06-0994 – ident: ref_122 doi: 10.1038/srep00170 – volume: 8 start-page: 1 year: 2016 ident: ref_125 article-title: Global investigation of composition and interaction networks in gut microbiomes of individuals belonging to diverse geographies and age-groups publication-title: Gut Pathog. doi: 10.1186/s13099-016-0099-z – volume: 35 start-page: 332 year: 2013 ident: ref_275 article-title: Acute nephrotoxicity of cisplatin: Molecular mechanisms publication-title: J. Bras. Nefrol. doi: 10.5935/0101-2800.20130052 – volume: 2 start-page: 457 year: 2015 ident: ref_296 article-title: Inhibition of 19s proteasome-associated deubiquitinases by metal-containing compounds publication-title: Oncoscience doi: 10.18632/oncoscience.167 – volume: 41 start-page: 5307 year: 2012 ident: ref_292 article-title: Synthesis and characterization of azolate gold (I) phosphane complexes as thioredoxin reductase inhibiting antitumor agents publication-title: Dalton Trans. doi: 10.1039/c2dt11781a – volume: 39 start-page: 44 year: 2007 ident: ref_248 article-title: Free radicals and antioxidants in normal physiological functions and human disease publication-title: Int. J. Biochem. Cell Boil. doi: 10.1016/j.biocel.2006.07.001 – volume: 48 start-page: 2135 year: 2016 ident: ref_67 article-title: microRNA-9 suppresses cell migration and invasion through downregulation of TM4SF1 in colorectal cancer publication-title: Int. J. Oncol. doi: 10.3892/ijo.2016.3430 – volume: 20 start-page: 237 year: 2004 ident: ref_183 article-title: Development of a fluorescent multiplex assay for detection of MSI-high tumors publication-title: Dis. Mark. doi: 10.1155/2004/136734 – ident: ref_303 doi: 10.1002/ejic.201600177 – ident: ref_161 doi: 10.1371/journal.pone.0053653 – volume: 22 start-page: 88 year: 2013 ident: ref_132 article-title: Sequencing the human microbiome in health and disease publication-title: Hum. Mol. Genet. doi: 10.1093/hmg/ddt398 – volume: 1 start-page: 11 year: 2001 ident: ref_235 article-title: Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2 publication-title: Nat. Rev. Cancer doi: 10.1038/35094017 – volume: 16 start-page: 1543 year: 2009 ident: ref_252 article-title: Antioxidants in wild mushrooms publication-title: Curr. Med. Chem. doi: 10.2174/092986709787909587 – volume: 48 start-page: 749 year: 2010 ident: ref_249 article-title: Reactive oxygen species, cellular redox systems, and apoptosis publication-title: Free Rad. Biol. Med. doi: 10.1016/j.freeradbiomed.2009.12.022 – volume: 74 start-page: 1651 year: 2014 ident: ref_109 article-title: PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-13-3159 – volume: 35 start-page: 1516 year: 2014 ident: ref_24 article-title: Metabolites of tobacco smoking and colorectal cancer risk publication-title: Carcinogenesis doi: 10.1093/carcin/bgu071 – volume: 66 start-page: 97 year: 2015 ident: ref_171 article-title: Health effects of changes in the structure of dietary macronutrients intake in western societies publication-title: Rocz. Panstw. Zakl. Hig. – volume: 13 start-page: 800 year: 2013 ident: ref_154 article-title: The microbiome and cancer publication-title: Nat. Rev. Cancer doi: 10.1038/nrc3610 – volume: 59 start-page: 5089 year: 1999 ident: ref_226 article-title: Compensatory lung growth after partial pneumonectomy enhances lung tumorigenesis induced by 3-methylcholanthrene publication-title: Cancer Res. – reference: 24648381 - Carcinogenesis. 2014 Jul;35(7):1516-22 – reference: 26101797 - Toxicol Lett. 2015 Sep 17;237(3):219-27 – reference: 23244617 - Antioxid Redox Signal. 2013 Oct 10;19(11):1266-303 – reference: 24618913 - PLoS One. 2014 Mar 11;9(3):e90731 – reference: 25367198 - BMC Cancer. 2014 Nov 03;14 :802 – reference: 24608084 - Curr Opin Chem Biol. 2014 Apr;19:144-53 – reference: 24196785 - Br J Cancer. 2014 Jan 7;110(1):164-71 – reference: 25105360 - J Clin Invest. 2014 Oct;124(10):4166-72 – reference: 19795455 - Int J Cancer. 2010 Mar 1;126(5):1177-86 – reference: 25043044 - Nature. 2014 Aug 7;512(7512):82-6 – reference: 20555112 - Ann Oncol. 2010 May;21 Suppl 5:v93-7 – reference: 24316222 - Mol Cell. 2014 Jan 9;53(1):88-100 – reference: 24859797 - Target Oncol. 2015 Mar;10(1):99-109 – reference: 16966692 - J Clin Oncol. 2006 Oct 10;24(29):4685-91 – reference: 2188735 - Cell. 1990 Jun 1;61(5):759-67 – reference: 20874843 - Cancer Sci. 2011 Jan;102(1):245-52 – reference: 26840372 - Cell Prolif. 2016 Feb;49(1):69-78 – reference: 17324124 - Am J Gastroenterol. 2007 Apr;102(4):803-13 – reference: 27131314 - Oncol Res. 2016;23 (6):283-90 – reference: 24922519 - Gut Microbes. 2014 May-Jun;5(3):411-8 – reference: 23335968 - PLoS One. 2013;8(1):e53653 – reference: 25862494 - Eur J Intern Med. 2015 May;26(4):285-91 – reference: 26106599 - Biomed Res Int. 2015;2015:149014 – reference: 26541655 - Rev Esp Enferm Dig. 2015 Nov;107(11):659-71 – reference: 22236158 - Curr Top Med Chem. 2012;12(3):219-35 – reference: 12018902 - Dig Dis Sci. 2002 May;47(5):1073-9 – reference: 18501714 - FEBS Lett. 2008 Jun 11;582(13):1919-27 – reference: 11801553 - Clin Cancer Res. 2002 Jan;8(1):156-64 – reference: 25634450 - Anticancer Agents Med Chem. 2015;15(6):773-82 – reference: 22355685 - Sci Rep. 2011;1:170 – reference: 24156022 - Cancer Med. 2013 Aug;2(4):496-506 – reference: 19926638 - Carcinogenesis. 2010 Mar;31(3):350-8 – reference: 27119506 - Oncotarget. 2016 Jun 14;7(24):35789-35802 – reference: 20724028 - J Am Acad Dermatol. 2012 May;66(5):e159-65 – reference: 26999740 - Oncology. 2016;90(4):221-31 – reference: 23796952 - Genome Res. 2013 Sep;23 (9):1446-61 – reference: 21490705 - J Biomed Biotechnol. 2011;2011:792362 – reference: 20304247 - Lancet. 2010 Mar 20;375(9719):1030-47 – reference: 16125380 - Eur J Cancer. 2005 Sep;41(14):2060-70 – reference: 22699611 - Nature. 2012 May 09;486(7402):222-7 – reference: 26097878 - Oncoscience. 2015 May 31;2(5):457-66 – reference: 26718210 - Tumour Biol. 2016 Mar;37(3):2805-10 – reference: 26792278 - Dig Dis Sci. 2016 Jun;61(6):1553-60 – reference: 25341011 - Annu Rev Med. 2015;66:83-95 – reference: 19223544 - Cancer Res. 2009 Mar 1;69(5):1851-7 – reference: 10979111 - JAMA. 2000 Sep 13;284(10):1247-55 – reference: 24267037 - Nutr Res. 2013 Dec;33(12 ):983-94 – reference: 22605513 - Cancer. 2012 Nov 1;118(21):5234-44 – reference: 27080879 - Food Chem. 2016 Sep 15;207 :51-9 – reference: 8339210 - Cancer. 1993 Aug 15;72(4):1171-7 – reference: 18212090 - Ann Oncol. 2008 May;19(5):935-8 – reference: 20426454 - J Agric Food Chem. 2010 May 26;58(10):6277-84 – reference: 21992995 - Br J Nutr. 2012 Jun;107(11):1623-34 – reference: 16651366 - Hum Mol Genet. 2006 Apr 15;15 Spec No 1:R17-29 – reference: 22810696 - Nature. 2012 Jul 18;487(7407):330-7 – reference: 26206497 - Tumour Biol. 2016 Jan;37(1):299-303 – reference: 21804560 - Nat Biotechnol. 2011 Jul 31;29(8):742-9 – reference: 23223325 - Chem Commun (Camb). 2013 May 14;49(39):4364-6 – reference: 23640607 - Med Oncol. 2013;30(2):588 – reference: 26299805 - Oncotarget. 2015 Aug 28;6(25):20785-800 – reference: 19445043 - Eur J Gastroenterol Hepatol. 2009 Jun;21(6):688-92 – reference: 24972311 - Immunol Lett. 2014 Dec;162(2 Pt A):54-61 – reference: 20846378 - J Exp Clin Cancer Res. 2010 Sep 16;29:128 – reference: 24585723 - Ann Oncol. 2014 May;25(5):1032-8 – reference: 23954159 - Cell Host Microbe. 2013 Aug 14;14(2):207-15 – reference: 14970275 - J Natl Cancer Inst. 2004 Feb 18;96(4):261-8 – reference: 25914517 - J Porphyr Phthalocyanines. 2015 Jan;19(1-03):398-403 – reference: 20656465 - Curr Opin Immunol. 2010 Aug;22(4):455-60 – reference: 24166914 - Clin Cancer Res. 2013 Dec 15;19(24):6669-77 – reference: 24330491 - J Exp Clin Cancer Res. 2013 Dec 13;32:104 – reference: 23395002 - Mol Cell. 2013 Mar 28;49(6):1083-96 – reference: 1659272 - Ann Intern Med. 1991 Dec 15;115(12):952-4 – reference: 12422229 - Acta Biochim Pol. 2002;49(3):583-96 – reference: 20553070 - Asian Pac J Cancer Prev. 2010;11 Suppl 2:81-98 – reference: 26250158 - Protein Cell. 2015 Sep;6(9):680-8 – reference: 27467555 - PLoS One. 2016 Jul 28;11(7):e0159136 – reference: 17686012 - Environ Microbiol. 2007 Sep;9(9):2125-36 – reference: 10919656 - Cancer Res. 2000 Jul 15;60(14):3823-31 – reference: 26889237 - Exp Ther Med. 2016 Jan;11(1):183-190 – reference: 18445765 - Exp Biol Med (Maywood). 2008 Jul;233(7):810-7 – reference: 21850056 - ISME J. 2012 Feb;6(2):320-9 – reference: 11900248 - Nat Rev Cancer. 2001 Oct;1(1):11-21 – reference: 19355906 - Curr Med Chem. 2009;16(12):1543-60 – reference: 11247898 - Gut. 2001 Apr;48(4):526-35 – reference: 24629967 - Food Chem. 2014 Aug 1;156:264-70 – reference: 25919227 - Nat Commun. 2015 Apr 28;6:6342 – reference: 19282466 - Ann Oncol. 2009 Jul;20(7):1223-9 – reference: 18444144 - Nutr Cancer. 2008;60(2):131-44 – reference: 20337575 - Curr Pharm Des. 2010 Jun;16(16):1813-25 – reference: 25864640 - Syst Appl Microbiol. 2015 Jun;38(4):276-86 – reference: 27077133 - AIMS Biophys. 2015;2(4):794-809 – reference: 26319099 - J Natl Cancer Inst. 2015 Aug 29;107(11): – reference: 18848448 - Trends Cell Biol. 2008 Dec;18(12):587-96 – reference: 15668707 - Br J Cancer. 2005 Feb 14;92(3):434-44 – reference: 26695747 - Alcohol Res. 2015;37(2):223-36 – reference: 22393467 - Genes Cancer. 2011 Aug;2(8):829-40 – reference: 26469679 - Dalton Trans. 2016 Feb 14;45(6):2462-75 – reference: 15582059 - Lancet. 2004 Dec 4-10;364(9450):2021-9 – reference: 25589621 - Clin Cancer Res. 2015 Mar 15;21(6):1313-20 – reference: 22202066 - Front Biosci (Schol Ed). 2012 Jan 01;4:375-91 – reference: 25758642 - Nat Commun. 2015 Mar 11;6:6528 – reference: 24157605 - J Inorg Biochem. 2014 Jan;130:32-7 – reference: 26820227 - Cancer Lett. 2016 Apr 10;373(2):203-13 – reference: 16611269 - Aliment Pharmacol Ther. 2006 Apr 15;23(8):1097-104 – reference: 25303894 - Curr Cardiol Rep. 2014 Nov;16(11):540 – reference: 18773902 - Gastroenterology. 2008 Oct;135(4):1079-99 – reference: 25498959 - Br J Nutr. 2015 Jan;113 Suppl:S1-5 – reference: 25332394 - Nucleic Acids Res. 2015 Jan;43(Database issue):D168-73 – reference: 25970450 - Nature. 2015 May 14;521(7551):S1 – reference: 16978905 - Int J Biochem Cell Biol. 2007;39(1):44-84 – reference: 26697569 - J Gastrointestin Liver Dis. 2015 Dec;24(4):435-43 – reference: 22357840 - Clin Cancer Res. 2012 Apr 15;18(8):2257-68 – reference: 26150664 - Philos Trans R Soc Lond B Biol Sci. 2015 Aug 19;370(1675):null – reference: 17664471 - J Clin Oncol. 2007 Aug 1;25(22):3230-7 – reference: 6426923 - Drugs. 1984 May;27(5):378-424 – reference: 10944126 - J Clin Oncol. 2000 Aug;18(16):2938-47 – reference: 25886253 - PLoS One. 2015 Apr 17;10(4):e0124487 – reference: 24732792 - Eur J Med Chem. 2014 May 22;79:164-72 – reference: 20045723 - Free Radic Biol Med. 2010 Mar 15;48(6):749-62 – reference: 20716914 - Oxid Med Cell Longev. 2009 Nov-Dec;2(5):270-8 – reference: 23558140 - J Med Microbiol. 2013 Aug;62(Pt 8):1107-23 – reference: 19001346 - J Clin Oncol. 2008 Dec 10;26(35):5668-70 – reference: 24350852 - Curr Med Chem. 2014 Apr;21(10):1220-30 – reference: 21637793 - PLoS Genet. 2011 May;7(5):e1002071 – reference: 26779313 - Oncol Rev. 2015 Dec 28;9(1):288 – reference: 26983891 - Int J Oncol. 2016 May;48(5):2135-43 – reference: 23741026 - Cancer Genomics Proteomics. 2013 May-Jun;10(3):93-113 – reference: 15051756 - J Clin Oncol. 2004 May 1;22(9):1564-71 – reference: 25666060 - Philos Trans A Math Phys Eng Sci. 2015 Mar 13;373(2037):null – reference: 11890990 - Cancer Genet Cytogenet. 2002 Feb;133(1):55-60 – reference: 11693338 - Am J Gastroenterol. 2001 Oct;96(10):2992-3003 – reference: 26804248 - Pharmacol Res. 2016 Apr;106:27-36 – reference: 25632202 - World J Gastroenterol. 2015 Jan 28;21(4):1275-83 – reference: 27142899 - Acta Cir Bras. 2016;31 Suppl 1:13-8 – reference: 26922981 - New Microbiol. 2016 Jan;39(1):1-12 – reference: 24678344 - Ecancermedicalscience. 2014 Jan 24;8:389 – reference: 24334760 - Clin Cancer Res. 2014 Feb 15;20(4):859-67 – reference: 17047121 - Gut. 2006 Nov;55(11):1671-2 – reference: 22201596 - Curr Pharm Biotechnol. 2013;14(3):274-88 – reference: 10537279 - Cancer Res. 1999 Oct 15;59(20):5089-92 – reference: 23651576 - J Laryngol Otol. 2013 Jun;127(6):536-41 – reference: 25650335 - J Pharm Pharmacol. 2015 May;67(5):685-95 – reference: 21206494 - Br J Cancer. 2011 Feb 1;104(3):488-95 – reference: 16620202 - Lett Appl Microbiol. 2006 May;42(5):452-8 – reference: 26935905 - Int J Oncol. 2016 May;48(5):1977-84 – reference: 26259252 - Oncotarget. 2015 Sep 15;6(27):24448-62 – reference: 21266362 - Cancer Res. 2011 Feb 1;71(3):725-35 – reference: 20420947 - Gastroenterology. 2010 Jun;138(6):2073-2087.e3 – reference: 27004000 - World J Gastroenterol. 2016 Mar 21;22(11):3227-33 – reference: 10922385 - J Med Genet. 2000 Aug;37(8):588-92 – reference: 21441351 - FASEB J. 2011 Jul;25(7):2305-12 – reference: 23962553 - Clin Gastroenterol Hepatol. 2014 Jul;12(7):1059-68 – reference: 26024397 - Rocz Panstw Zakl Hig. 2015;66(2):97-105 – reference: 19142968 - Int J Cancer. 2009 May 15;124(10):2406-15 – reference: 14973550 - Oncogene. 2004 Feb 19;23(7):1377-91 – reference: 20551304 - Cancer Epidemiol Biomarkers Prev. 2010 Jul;19(7):1766-74 – reference: 16916273 - Expert Opin Investig Drugs. 2006 Sep;15(9):1067-75 – reference: 24818718 - Adv Exp Med Biol. 2014;816:25-52 – reference: 19738126 - J Clin Oncol. 2009 Oct 20;27(30):5068-74 – reference: 20619739 - Lancet Oncol. 2010 Aug;11(8):753-62 – reference: 20593091 - Dalton Trans. 2010 Sep 21;39(35):8113-27 – reference: 16723681 - Clin Chem. 2006 Jun;52(6):1062-9 – reference: 16166455 - Clin Cancer Res. 2005 Sep 15;11(18):6738-44 – reference: 21665895 - Carcinogenesis. 2011 Aug;32(8):1207-15 – reference: 15486743 - Dis Colon Rectum. 2004 Sep;47(9):1467-82 – reference: 17320769 - Free Radic Biol Med. 2007 Mar 15;42(6):872-81 – reference: 23295318 - Ann Surg. 2013 Jun;257(6):1053-8 – reference: 25311658 - Proteomics Clin Appl. 2015 Feb;9(1-2):64-71 – reference: 25561781 - World J Gastroenterol. 2014 Dec 28;20(48):18121-30 – reference: 24402113 - J Bras Nefrol. 2013 Oct-Dec;35(4):332-40 – reference: 26573378 - Mol Med Rep. 2016 Jan;13(1):273-80 – reference: 26673620 - Oncotarget. 2016 Jan 19;7(3):2660-71 – reference: 23733170 - Microb Ecol. 2013 Aug;66(2):462-70 – reference: 15521051 - J Gene Med. 2005 Mar;7(3):366-74 – reference: 26801617 - J Transl Med. 2016 Jan 22;14 :21 – reference: 25123079 - Curr Oncol Rep. 2014 Oct;16(10):406 – reference: 18481151 - Ann Surg Oncol. 2008 Aug;15(8):2120-8 – reference: 18755897 - Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13421-6 – reference: 23332725 - Trends Microbiol. 2013 Apr;21(4):167-73 – reference: 1988084 - Cancer Res. 1991 Jan 1;51(1):2-4 – reference: 14644332 - Mutat Res. 2003 Nov;544(2-3):305-11 – reference: 25698589 - Drugs R D. 2015 Mar;15(1):13-20 – reference: 25991585 - Int J Cancer. 2015 Nov 15;137(10):2310-22 – reference: 25132422 - Cancer Epidemiol. 2014 Oct;38(5):583-90 – reference: 24473064 - Cancer Res. 2014 Mar 15;74(6):1651-60 – reference: 24194538 - MBio. 2013 Nov 05;4(6):e00692-13 – reference: 22861806 - Nutr Rev. 2012 Aug;70 Suppl 1:S38-44 – reference: 21607947 - Int J Cancer. 2011 Dec 1;129(11):2712-9 – reference: 25190710 - Ann Oncol. 2014 Sep;25 Suppl 3:iii1-9 – reference: 21189131 - Curr Top Med Chem. 2011;11(5):521-42 – reference: 22067406 - J Clin Oncol. 2011 Dec 10;29(35):4620-6 – reference: 25929517 - BMC Cancer. 2015 May 01;15:340 – reference: 18832519 - Gut. 2009 Jan;58(1):90-6 – reference: 23143645 - J Cancer Res Clin Oncol. 2013 Mar;139(3):437-45 – reference: 25480414 - Tumour Biol. 2015 Apr;36(4):2675-84 – reference: 15789122 - Nat Rev Drug Discov. 2005 Apr;4(4):307-20 – reference: 22611467 - Am J Transl Res. 2012;4(2):127-50 – reference: 23785428 - PLoS One. 2013 Jun 13;8(6):e65479 – reference: 27175113 - Intest Res. 2016 Apr;14(2):127-38 – reference: 21098318 - J Clin Oncol. 2011 Jan 1;29(1):17-24 – reference: 26841791 - J Biol Inorg Chem. 2016 Apr;21(2):275-92 – reference: 14602737 - J Clin Endocrinol Metab. 2003 Nov;88(11):5119-26 – reference: 23634186 - Therap Adv Gastroenterol. 2013 May;6(3):215-29 – reference: 27158266 - Gut Pathog. 2016 May 06;8:17 – reference: 26811607 - World J Gastroenterol. 2016 Jan 14;22(2):557-66 – reference: 22931591 - Mini Rev Med Chem. 2012 Oct;12 (12 ):1193-201 – reference: 23719549 - Am J Clin Nutr. 2013 Jul;98(1):111-20 – reference: 26780942 - Mol Med Rep. 2016 Mar;13(3):2221-8 – reference: 25305284 - Clin Infect Dis. 2015 Jan 15;60(2):208-15 – reference: 26103003 - Exp Mol Pathol. 2015 Aug;99(1):173-9 – reference: 26340103 - Curr Opin Biotechnol. 2015 Dec;36:137-45 – reference: 18497261 - Science. 2008 Jun 20;320(5883):1647-51 – reference: 25540872 - BMC Infect Dis. 2014 Dec 24;14:733 – reference: 20621017 - J Genet Genomics. 2010 Jun;37(6):347-58 – reference: 21970482 - Arch Pathol Lab Med. 2011 Oct;135(10 ):1269-77 – reference: 26622375 - Exp Ther Med. 2015 Aug;10(2):683-688 – reference: 24336217 - Nature. 2014 Jan 23;505(7484):559-63 – reference: 23943792 - Hum Mol Genet. 2013 Oct 15;22(R1):R88-94 – reference: 17348452 - Anticancer Res. 2007 Jan-Feb;27(1B):627-33 – reference: 18949397 - Oncol Rep. 2008 Nov;20(5):1029-33 – reference: 19351210 - Mol Diagn Ther. 2009;13(1):11-4 – reference: 16189152 - J Clin Pathol. 2005 Oct;58(10):1064-8 – reference: 17968323 - Oncogene. 2008 Apr 3;27(15):2128-36 – reference: 21112873 - Nucleic Acids Res. 2011 Jan;39(Database issue):D146-51 – reference: 24776770 - Nat Rev Genet. 2014 Jun;15(6):423-37 – reference: 18322143 - CA Cancer J Clin. 2008 May-Jun;58(3):130-60 – reference: 24503701 - PLoS One. 2014 Feb 04;9(2):e87456 – reference: 20393566 - Nature. 2010 Apr 15;464(7291):1071-6 – reference: 24574765 - World J Gastroenterol. 2014 Jan 28;20(4):908-22 – reference: 22018986 - Cancer Lett. 2012 Jan 28;314(2):223-31 – reference: 16804544 - Nat Genet. 2006 Jul;38(7):787-93 – reference: 26257129 - Dig Liver Dis. 2015 Dec;47(12):1007-12 – reference: 25940732 - Biochem J. 2015 May 15;468(1):1-15 – reference: 20577206 - Nature. 2010 Jun 24;465(7301):1033-8 – reference: 21811294 - Eur J Clin Nutr. 2012 Jan;66(1):53-60 – reference: 16239904 - Nat Rev Cancer. 2005 Nov;5(11):845-56 – reference: 21503572 - Int J Oncol. 2011 Jul;39(1):169-75 – reference: 19088354 - JAMA. 2008 Dec 17;300(23):2765-78 – reference: 15644551 - JAMA. 2005 Jan 12;293(2):233-4 – reference: 25297801 - J Surg Oncol. 2015 Jan;111(1):96-102 – reference: 24976724 - World J Gastroenterol. 2014 Jun 28;20(24):7878-86 – reference: 12621137 - N Engl J Med. 2003 Mar 6;348(10):919-32 – reference: 15821245 - Oncologist. 2005 Apr;10 (4):250-61 – reference: 21984339 - J Pathol. 2012 Feb;226(3):544-55 – reference: 16965397 - Cancer Sci. 2006 Nov;97(11):1147-54 – reference: 24220557 - J Clin Oncol. 2013 Dec 20;31(36):4512-9 – reference: 21934092 - Carcinogenesis. 2011 Dec;32(12):1798-805 – reference: 21489289 - Mol Cancer. 2011 Apr 13;10:38 – reference: 25266735 - Cancer Discov. 2014 Dec;4(12):1387-97 – reference: 22020560 - Int J Cancer. 2012 Sep 1;131(5):1042-51 – reference: 15528789 - Dis Markers. 2004;20(4-5):237-50 – reference: 22676885 - Br J Nutr. 2012 Sep;108(5):820-31 – reference: 26071354 - Biochem Biophys Res Commun. 2015 Aug 7;463(4):954-60 – reference: 23102266 - Mol Cell. 2012 Oct 26;48(2):158-67 – reference: 22009203 - Nat Rev Gastroenterol Hepatol. 2011 Oct 18;8(12):686-700 – reference: 8646726 - Cancer. 1996 Jul 1;78(1):48-56 – reference: 25058905 - Eur J Pharmacol. 2014 Oct 5;740:364-78 – reference: 25514560 - Nutrients. 2014 Dec 11;6(12):5786-805 – reference: 22391922 - Dalton Trans. 2012 May 7;41(17 ):5307-18 – reference: 24439901 - Cell Host Microbe. 2014 Jan 15;15(1):95-102 – reference: 25849657 - Int J Mol Sci. 2015 Apr 02;16(4):7493-519 – reference: 21209396 - Cancer Prev Res (Phila). 2011 Feb;4(2):177-84 – reference: 24132111 - Nat Rev Cancer. 2013 Nov;13(11):800-12 – reference: 24519959 - Mol Carcinog. 2015 Sep;54(9):742-50 – reference: 22154408 - Clin Colorectal Cancer. 2012 Jun;11(2):93-100 – reference: 17932341 - Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):1935-53 – reference: 21764859 - Cancer Prev Res (Phila). 2011 Nov;4(11):1895-902 – reference: 26349975 - Biomed Pharmacother. 2015 Aug;74:138-44 – reference: 20420946 - Gastroenterology. 2010 Jun;138(6):2059-72 – reference: 23325619 - Bioinformatics. 2013 Mar 1;29(5):638-44 – reference: 24594601 - Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4173-8 – reference: 20705936 - J Natl Cancer Inst. 2010 Oct 6;102(19):1462-7 – reference: 24068536 - World J Microbiol Biotechnol. 2014 Feb;30(2):351-74 – reference: 11720434 - Br J Cancer. 2001 Nov 16;85(10):1492-8 – reference: 15082451 - Alcohol Alcohol. 2004 May-Jun;39(3):155-65 – reference: 14576837 - Oncogene. 2003 Oct 20;22(47):7265-79 – reference: 23558749 - Nucleic Acids Res. 2013 May;41(9):4976-87 – reference: 18486167 - Trans R Soc Trop Med Hyg. 2008 Aug;102(8):735-42 – reference: 19911377 - J Cell Biochem. 2010 Jan 1;109(1):162-72 – reference: 19505922 - Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1888-93 – reference: 15713944 - N Engl J Med. 2005 Mar 17;352(11):1071-80 – reference: 26254872 - Cell Mol Life Sci. 2015 Nov;72(22):4287-308 – reference: 26629312 - World J Biol Chem. 2015 Nov 26;6(4):290-300 – reference: 23603043 - Anaerobe. 2013 Dec;24:102-6 – reference: 14688025 - Carcinogenesis. 2004 Apr;25(4):527-33 – reference: 24710310 - Oncologist. 2014 May;19(5):492-7 |
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| SubjectTerms | Bacteroides fragilis Cancer therapies Chemotherapy Colorectal cancer Colorectal Neoplasms - epidemiology Colorectal Neoplasms - etiology Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Escherichia coli Fusobacterium Genetic Predisposition to Disease Humans Mutation Neoplasm Staging Review Risk Factors Signal Transduction |
| Title | Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer |
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