Topical imiquimod compared with conization to treat cervical high-grade squamous intraepithelial lesions: Multicenter, randomized controlled trial

In a previous phase II trial, we showed that topical imiquimod (IMQ) therapy is an efficacious treatment for high-grade squamous intraepithelial lesion (HSIL). Aim of the present study was to investigate the non-inferiority of a 16-week topical, self-applied IMQ therapy compared to large loop excisi...

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Bibliographic Details
Published in:	Gynecologic oncology Vol. 165; no. 1; pp. 23 - 29
Main Authors:	Polterauer, Stephan, Reich, Olaf, Widschwendter, Andreas, Hadjari, Laudia, Bogner, Gerhard, Reinthaller, Alexander, Joura, Elmar, Trutnovsky, Gerda, Ciresa-Koenig, Alexandra, Ganhoer-Schimboeck, Julia, Boehm, Ina, Berger, Regina, Langthaler, Eva, Aberle, Stephan W., Heinze, Georg, Gleiss, Andreas, Grimm, Christoph
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.04.2022
Subjects:	Cervical intraepithelial neoplasia CIN Conization Hematology, Oncology, and Palliative Medicine High-grade squamous intraepithelial lesion HPV HSIL Human papillomavirus Imiquimod Large loop excision of the transformation zone LLETZ Obstetrics and Gynecology Large loop excision of the transformation zone High-grade squamous intraepithelial lesion Conization Human papillomavirus Imiquimod Cervical intraepithelial neoplasia CIN LLETZ HPV HSIL
ISSN:	0090-8258, 1095-6859, 1095-6859
Online Access:	Get full text
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