LncRNA GAS5 downregulates NLRP3 inflammasome activation-mediated pyroptosis in sepsis-induced myocardial injury by targeting SIRT3/AMPKα

An increasing body of studies has demonstrated the significance of long non-coding RNA (lncRNA) growth arrest specific 5 (GAS5) in inflammation and myocardial injury in septic shock. This research aims to determine whether GAS5 contributes to the pathological development of sepsis-induced cardiac da...

Full description

Saved in:

Bibliographic Details
Published in:	Heliyon Vol. 9; no. 12; p. e22939
Main Authors:	Luo, Minghao, Peng, Yuce, Lv, Dingyi, Xue, Yuzhou, Huang, Longxiang, Hu, Yu, Zhu, Wenyan, Luo, Suxin, Shen, Jian, Li, Xiang
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.12.2023 Elsevier
Subjects:	GAS5 inflammasomes inflammation lipopolysaccharides loss-of-function mutation mice Myocardial injury non-coding RNA Pyroptosis Sepsis septic shock surgery survival rate Sepsis Pyroptosis GAS5 Myocardial injury
ISSN:	2405-8440, 2405-8440
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!