CONRAD—A software framework for cone-beam imaging in radiology

Purpose: In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and can only be used within a certain lab. Often the same algorithm is implemented multiple times by different groups in order to enabl...

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Veröffentlicht in:Medical physics (Lancaster) Jg. 40; H. 11; S. 111914 - n/a
Hauptverfasser: Maier, Andreas, Hofmann, Hannes G., Berger, Martin, Fischer, Peter, Schwemmer, Chris, Wu, Haibo, Müller, Kerstin, Hornegger, Joachim, Choi, Jang-Hwan, Riess, Christian, Keil, Andreas, Fahrig, Rebecca
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States American Association of Physicists in Medicine 01.11.2013
2013 Author(s)
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ISSN:0094-2405, 2473-4209, 2473-4209, 0094-2405
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Abstract Purpose: In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and can only be used within a certain lab. Often the same algorithm is implemented multiple times by different groups in order to enable comparison. In an effort to tackle this problem, the authors created CONRAD, a software framework that provides many of the tools that are required to simulate basic processes in x-ray imaging and perform image reconstruction with consideration of nonlinear physical effects. Methods: CONRAD is a Java-based state-of-the-art software platform with extensive documentation. It is based on platform-independent technologies. Special libraries offer access to hardware acceleration such as OpenCL. There is an easy-to-use interface for parallel processing. The software package includes different simulation tools that are able to generate up to 4D projection and volume data and respective vector motion fields. Well known reconstruction algorithms such as FBP, DBP, and ART are included. All algorithms in the package are referenced to a scientific source. Results: A total of 13 different phantoms and 30 processing steps have already been integrated into the platform at the time of writing. The platform comprises 74.000 nonblank lines of code out of which 19% are used for documentation. The software package is available for download athttp://conrad.stanford.edu. To demonstrate the use of the package, the authors reconstructed images from two different scanners, a table top system and a clinical C-arm system. Runtimes were evaluated using the RabbitCT platform and demonstrate state-of-the-art runtimes with 2.5 s for the 256 problem size and 12.4 s for the 512 problem size. Conclusions: As a common software framework, CONRAD enables the medical physics community to share algorithms and develop new ideas. In particular this offers new opportunities for scientific collaboration and quantitative performance comparison between the methods of different groups.
AbstractList In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and can only be used within a certain lab. Often the same algorithm is implemented multiple times by different groups in order to enable comparison. In an effort to tackle this problem, the authors created CONRAD, a software framework that provides many of the tools that are required to simulate basic processes in x-ray imaging and perform image reconstruction with consideration of nonlinear physical effects. CONRAD is a Java-based state-of-the-art software platform with extensive documentation. It is based on platform-independent technologies. Special libraries offer access to hardware acceleration such as OpenCL. There is an easy-to-use interface for parallel processing. The software package includes different simulation tools that are able to generate up to 4D projection and volume data and respective vector motion fields. Well known reconstruction algorithms such as FBP, DBP, and ART are included. All algorithms in the package are referenced to a scientific source. A total of 13 different phantoms and 30 processing steps have already been integrated into the platform at the time of writing. The platform comprises 74.000 nonblank lines of code out of which 19% are used for documentation. The software package is available for download at http://conrad.stanford.edu. To demonstrate the use of the package, the authors reconstructed images from two different scanners, a table top system and a clinical C-arm system. Runtimes were evaluated using the RabbitCT platform and demonstrate state-of-the-art runtimes with 2.5 s for the 256 problem size and 12.4 s for the 512 problem size. As a common software framework, CONRAD enables the medical physics community to share algorithms and develop new ideas. In particular this offers new opportunities for scientific collaboration and quantitative performance comparison between the methods of different groups.
Purpose: In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and can only be used within a certain lab. Often the same algorithm is implemented multiple times by different groups in order to enable comparison. In an effort to tackle this problem, the authors created CONRAD, a software framework that provides many of the tools that are required to simulate basic processes in x-ray imaging and perform image reconstruction with consideration of nonlinear physical effects.Methods: CONRAD is a Java-based state-of-the-art software platform with extensive documentation. It is based on platform-independent technologies. Special libraries offer access to hardware acceleration such as OpenCL. There is an easy-to-use interface for parallel processing. The software package includes different simulation tools that are able to generate up to 4D projection and volume data and respective vector motion fields. Well known reconstruction algorithms such as FBP, DBP, and ART are included. All algorithms in the package are referenced to a scientific source.Results: A total of 13 different phantoms and 30 processing steps have already been integrated into the platform at the time of writing. The platform comprises 74.000 nonblank lines of code out of which 19% are used for documentation. The software package is available for download at http://conrad.stanford.edu. To demonstrate the use of the package, the authors reconstructed images from two different scanners, a table top system and a clinical C-arm system. Runtimes were evaluated using the RabbitCT platform and demonstrate state-of-the-art runtimes with 2.5 s for the 256 problem size and 12.4 s for the 512 problem size.Conclusions: As a common software framework, CONRAD enables the medical physics community to share algorithms and develop new ideas. In particular this offers new opportunities for scientific collaboration and quantitative performance comparison between the methods of different groups.
Purpose: In the community of x‐ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and can only be used within a certain lab. Often the same algorithm is implemented multiple times by different groups in order to enable comparison. In an effort to tackle this problem, the authors created CONRAD, a software framework that provides many of the tools that are required to simulate basic processes in x‐ray imaging and perform image reconstruction with consideration of nonlinear physical effects. Methods: CONRAD is a Java‐based state‐of‐the‐art software platform with extensive documentation. It is based on platform‐independent technologies. Special libraries offer access to hardware acceleration such as OpenCL. There is an easy‐to‐use interface for parallel processing. The software package includes different simulation tools that are able to generate up to 4D projection and volume data and respective vector motion fields. Well known reconstruction algorithms such as FBP, DBP, and ART are included. All algorithms in the package are referenced to a scientific source. Results: A total of 13 different phantoms and 30 processing steps have already been integrated into the platform at the time of writing. The platform comprises 74.000 nonblank lines of code out of which 19% are used for documentation. The software package is available for download athttp://conrad.stanford.edu. To demonstrate the use of the package, the authors reconstructed images from two different scanners, a table top system and a clinical C‐arm system. Runtimes were evaluated using the RabbitCT platform and demonstrate state‐of‐the‐art runtimes with 2.5 s for the 256 problem size and 12.4 s for the 512 problem size. Conclusions: As a common software framework, CONRAD enables the medical physics community to share algorithms and develop new ideas. In particular this offers new opportunities for scientific collaboration and quantitative performance comparison between the methods of different groups.
In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and can only be used within a certain lab. Often the same algorithm is implemented multiple times by different groups in order to enable comparison. In an effort to tackle this problem, the authors created CONRAD, a software framework that provides many of the tools that are required to simulate basic processes in x-ray imaging and perform image reconstruction with consideration of nonlinear physical effects.PURPOSEIn the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and can only be used within a certain lab. Often the same algorithm is implemented multiple times by different groups in order to enable comparison. In an effort to tackle this problem, the authors created CONRAD, a software framework that provides many of the tools that are required to simulate basic processes in x-ray imaging and perform image reconstruction with consideration of nonlinear physical effects.CONRAD is a Java-based state-of-the-art software platform with extensive documentation. It is based on platform-independent technologies. Special libraries offer access to hardware acceleration such as OpenCL. There is an easy-to-use interface for parallel processing. The software package includes different simulation tools that are able to generate up to 4D projection and volume data and respective vector motion fields. Well known reconstruction algorithms such as FBP, DBP, and ART are included. All algorithms in the package are referenced to a scientific source.METHODSCONRAD is a Java-based state-of-the-art software platform with extensive documentation. It is based on platform-independent technologies. Special libraries offer access to hardware acceleration such as OpenCL. There is an easy-to-use interface for parallel processing. The software package includes different simulation tools that are able to generate up to 4D projection and volume data and respective vector motion fields. Well known reconstruction algorithms such as FBP, DBP, and ART are included. All algorithms in the package are referenced to a scientific source.A total of 13 different phantoms and 30 processing steps have already been integrated into the platform at the time of writing. The platform comprises 74.000 nonblank lines of code out of which 19% are used for documentation. The software package is available for download at http://conrad.stanford.edu. To demonstrate the use of the package, the authors reconstructed images from two different scanners, a table top system and a clinical C-arm system. Runtimes were evaluated using the RabbitCT platform and demonstrate state-of-the-art runtimes with 2.5 s for the 256 problem size and 12.4 s for the 512 problem size.RESULTSA total of 13 different phantoms and 30 processing steps have already been integrated into the platform at the time of writing. The platform comprises 74.000 nonblank lines of code out of which 19% are used for documentation. The software package is available for download at http://conrad.stanford.edu. To demonstrate the use of the package, the authors reconstructed images from two different scanners, a table top system and a clinical C-arm system. Runtimes were evaluated using the RabbitCT platform and demonstrate state-of-the-art runtimes with 2.5 s for the 256 problem size and 12.4 s for the 512 problem size.As a common software framework, CONRAD enables the medical physics community to share algorithms and develop new ideas. In particular this offers new opportunities for scientific collaboration and quantitative performance comparison between the methods of different groups.CONCLUSIONSAs a common software framework, CONRAD enables the medical physics community to share algorithms and develop new ideas. In particular this offers new opportunities for scientific collaboration and quantitative performance comparison between the methods of different groups.
Author Hofmann, Hannes G.
Keil, Andreas
Choi, Jang-Hwan
Hornegger, Joachim
Müller, Kerstin
Maier, Andreas
Schwemmer, Chris
Fischer, Peter
Wu, Haibo
Riess, Christian
Berger, Martin
Fahrig, Rebecca
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  surname: Maier
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  email: andreas.maier@cs.fau.de
  organization: Department of Radiology, Stanford University, Stanford, California 94305
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  givenname: Hannes G.
  surname: Hofmann
  fullname: Hofmann, Hannes G.
  organization: Pattern Recognition Laboratory, Department of Computer Science, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen 91058, Germany
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  givenname: Martin
  surname: Berger
  fullname: Berger, Martin
  organization: Pattern Recognition Laboratory, Department of Computer Science, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen 91058, Germany
– sequence: 4
  givenname: Peter
  surname: Fischer
  fullname: Fischer, Peter
  organization: Erlangen Graduate School in Advanced Optical Technologies (SAOT), Universität Erlangen-Nürnberg Pattern Recognition Laboratory, Department of Computer Science, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen 91058, Germany
– sequence: 5
  givenname: Chris
  surname: Schwemmer
  fullname: Schwemmer, Chris
  organization: Erlangen Graduate School in Advanced Optical Technologies (SAOT), Universität Erlangen-Nürnberg Pattern Recognition Laboratory, Department of Computer Science, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen 91058, Germany
– sequence: 6
  givenname: Haibo
  surname: Wu
  fullname: Wu, Haibo
  organization: Erlangen Graduate School in Advanced Optical Technologies (SAOT), Universität Erlangen-Nürnberg Pattern Recognition Laboratory, Department of Computer Science, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen 91058, Germany
– sequence: 7
  givenname: Kerstin
  surname: Müller
  fullname: Müller, Kerstin
  organization: Erlangen Graduate School in Advanced Optical Technologies (SAOT), Universität Erlangen-Nürnberg Pattern Recognition Laboratory, Department of Computer Science, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen 91058, Germany
– sequence: 8
  givenname: Joachim
  surname: Hornegger
  fullname: Hornegger, Joachim
  organization: Erlangen Graduate School in Advanced Optical Technologies (SAOT), Universität Erlangen-Nürnberg Pattern Recognition Laboratory, Department of Computer Science, Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen 91058, Germany
– sequence: 9
  givenname: Jang-Hwan
  surname: Choi
  fullname: Choi, Jang-Hwan
  organization: Department of Radiology, Stanford University, Stanford, California 94305
– sequence: 10
  givenname: Christian
  surname: Riess
  fullname: Riess, Christian
  organization: Department of Radiology, Stanford University, Stanford, California 94305
– sequence: 11
  givenname: Andreas
  surname: Keil
  fullname: Keil, Andreas
  organization: Department of Radiology, Stanford University, Stanford, California 94305
– sequence: 12
  givenname: Rebecca
  surname: Fahrig
  fullname: Fahrig, Rebecca
  organization: Department of Radiology, Stanford University, Stanford, California 94305
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Issue 11
Keywords software frameworks
cone-beam
open-source
hardware acceleration
GPU
C-arm computed tomography (CT)
Language English
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Author to whom correspondence should be addressed. Electronic mail: andreas.maier@cs.fau.de
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SSID ssj0006350
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Snippet Purpose: In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are...
Purpose: In the community of x‐ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are...
In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are proprietary and...
Purpose: In the community of x-ray imaging, there is a multitude of tools and applications that are used in scientific practice. Many of these tools are...
SourceID pubmedcentral
osti
proquest
pubmed
crossref
wiley
scitation
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 111914
SubjectTerms ALGORITHMS
Biological material, e.g. blood, urine; Haemocytometers
BIOMEDICAL RADIOGRAPHY
Computed radiography
Computed tomography
COMPUTER CODES
Computer Graphics
Computer Simulation
Computer software
Computerised tomographs
computerised tomography
COMPUTERIZED TOMOGRAPHY
Computers
Cone-Beam Computed Tomography
cone‐beam
C‐arm computed tomography (CT)
diagnostic radiography
Digital computing or data processing equipment or methods, specially adapted for specific applications
Equipment Design
Four-Dimensional Computed Tomography
GPU
hardware acceleration
Humans
Image data processing or generation, in general
IMAGE PROCESSING
Image Processing, Computer-Assisted
image reconstruction
Image sensors
Java
Medical image noise
medical image processing
Medical image reconstruction
Medical imaging
Medical X‐ray imaging
Motion
open‐source
PARALLEL PROCESSING
PHANTOMS
Phantoms, Imaging
Programming Languages
Radiation Imaging Physics
Radiographic Image Interpretation, Computer-Assisted - methods
RADIOLOGY AND NUCLEAR MEDICINE
Reconstruction
Software
software frameworks
software packages
User interfaces
User-Computer Interface
X RADIATION
X‐ray imaging
X‐ray scattering
Title CONRAD—A software framework for cone-beam imaging in radiology
URI http://dx.doi.org/10.1118/1.4824926
https://onlinelibrary.wiley.com/doi/abs/10.1118%2F1.4824926
https://www.ncbi.nlm.nih.gov/pubmed/24320447
https://www.proquest.com/docview/1492696305
https://www.osti.gov/biblio/22220267
https://pubmed.ncbi.nlm.nih.gov/PMC3820625
Volume 40
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