The measurement and clinical relevance of brain atrophy in multiple sclerosis

Brain atrophy has emerged as a clinically relevant component of disease progression in multiple sclerosis. Progressive loss of brain tissue bulk can be detected in vivo in a sensitive and reproducible manner by MRI. Clinical studies have shown that brain atrophy begins early in the disease course. T...

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Bibliographic Details

Published in:	Lancet neurology Vol. 5; no. 2; pp. 158 - 170
Main Authors:	Bermel, Robert A, Bakshi, Rohit
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.02.2006 Elsevier Limited
Subjects:	Atrophy Brain - pathology Disease Progression Humans Magnetic Resonance Imaging Multiple sclerosis Multiple Sclerosis - complications Pathology Prognosis Shrinkage
ISSN:	1474-4422, 1474-4465
Online Access:	Get full text
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