Pre- and early post-natal exposure to phthalates and DINCH in a new type of mother-child cohort relying on within-subject pools of repeated urine samples
For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for each participant over windows of sensitivity is expected to improve exposure characterization but has rarely been done. We aimed to rely on...
Uloženo v:
| Vydáno v: | Environmental pollution (1987) Ročník 287; s. 117650 |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
Elsevier Ltd
15.10.2021
Elsevier Elsevier Applied Science Publishers |
| Témata: | |
| ISSN: | 0269-7491, 1873-6424, 1873-6424 |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for each participant over windows of sensitivity is expected to improve exposure characterization but has rarely been done. We aimed to rely on within-subject pools of repeated urine samples to assess phthalate exposure during pregnancy and infancy.
Women of the French SEPAGES mother-child cohort were asked to collect three urine samples per day over seven consecutive days, twice during their pregnancy (approximatively second (T2) and third (T3) trimesters). For their infants they also collected one sample per day during a week at two (M2) and twelve months (M12). Samples were pooled (within-subject, within-period) prior to phthalate and DINCH metabolite concentrations assessment. Number of pooled samples assayed was 477, 456, 152 and 100 for T2, T3, M2 and M12, respectively. All metabolites were detected in more than 95% of the pooled samples except for the two DINCH metabolites (oh- and oxo-MINCH), MMCHP and oh-MPHP at M2 for which detection frequencies ranged between 64% and 88%. Maternal concentrations of MiBP, MBzP, DEHP metabolites and oxo-MiNP decreased between 2014 and 2017, whereas concentrations of oh-MiNP and the two DINCH metabolites increased (Mann-Kendall p-values < 0.05). While improved compared to studies that relied on spot samples, Intraclass Correlation Coefficients for the pregnancy were below 0.40 for most metabolites. Spearman correlation coefficients between pooled samples collected in infancy were lower than those observed during pregnancy, and were all below 0.30. Exposure to emerging phthalate substitutes such as DINCH and DPHP seems widespread among pregnant women and infants. Collecting repeated urine samples in pregnant women and infants is feasible. The relatively low correlation across trimesters and between maternal and infant samples highlights the need to collect biospecimens in the assumed sensitive time window.
[Display omitted]
•Repeated urine samples were collected and pooled within-subject, within period.•Metabolites of phthalates and DINCH were measured in pooled samples.•Frequencies of detection were overall high.•Pregnancy concentrations of MiBP, MBzP, DEHP and oxo-MINP decreased with time.•Pregnancy concentrations of oh-MiNP and DINCH metabolites increased with time.
Relying on a recent cohort (2014–2017) with repeated urine samples collected during pregnancy and infancy, we showed that exposure to phthalates and DINCH is still widespread in the general population. |
|---|---|
| AbstractList | For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for each participant over windows of sensitivity is expected to improve exposure characterization but has rarely been done. We aimed to rely on within-subject pools of repeated urine samples to assess phthalate exposure during pregnancy and infancy.Women of the French SEPAGES mother-child cohort were asked to collect three urine samples per day over seven consecutive days, twice during their pregnancy (approximatively second (T2) and third (T3) trimesters). For their infants they also collected one sample per day during a week at two (M2) and twelve months (M12). Samples were pooled (within-subject, within-period) prior to phthalate and DINCH metabolite concentrations assessment. Number of pooled samples assayed was 477, 456, 152 and 100 for T2, T3, M2 and M12, respectively. All metabolites were detected in more than 95% of the pooled samples except for the two DINCH metabolites (oh- and oxo-MINCH), MMCHP and oh-MPHP at M2 for which detection frequencies ranged between 64% and 88%. Maternal concentrations of MiBP, MBzP, DEHP metabolites and oxo-MiNP decreased between 2014 and 2017, whereas concentrations of oh-MiNP and the two DINCH metabolites increased (Mann-Kendall p-values < 0.05). While improved compared to studies that relied on spot samples, Intraclass Correlation Coefficients for the pregnancy were below 0.40 for most metabolites. Spearman correlation coefficients between pooled samples collected in infancy were lower than those observed during pregnancy, and were all below 0.30. Exposure to emerging phthalate substitutes such as DINCH and DPHP seems widespread among pregnant women and infants. Collecting repeated urine samples in pregnant women and infants is feasible. The relatively low correlation across trimesters and between maternal and infant samples highlights the need to collect biospecimens in the assumed sensitive time window. For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for each participant over windows of sensitivity is expected to improve exposure characterization but has rarely been done. We aimed to rely on within-subject pools of repeated urine samples to assess phthalate exposure during pregnancy and infancy. Women of the French SEPAGES mother-child cohort were asked to collect three urine samples per day over seven consecutive days, twice during their pregnancy (approximatively second (T2) and third (T3) trimesters). For their infants they also collected one sample per day during a week at two (M2) and twelve months (M12). Samples were pooled (within-subject, within-period) prior to phthalate and DINCH metabolite concentrations assessment. Number of pooled samples assayed was 477, 456, 152 and 100 for T2, T3, M2 and M12, respectively. All metabolites were detected in more than 95% of the pooled samples except for the two DINCH metabolites (oh- and oxo-MINCH), MMCHP and oh-MPHP at M2 for which detection frequencies ranged between 64% and 88%. Maternal concentrations of MiBP, MBzP, DEHP metabolites and oxo-MiNP decreased between 2014 and 2017, whereas concentrations of oh-MiNP and the two DINCH metabolites increased (Mann-Kendall p-values < 0.05). While improved compared to studies that relied on spot samples, Intraclass Correlation Coefficients for the pregnancy were below 0.40 for most metabolites. Spearman correlation coefficients between pooled samples collected in infancy were lower than those observed during pregnancy, and were all below 0.30. Exposure to emerging phthalate substitutes such as DINCH and DPHP seems widespread among pregnant women and infants. Collecting repeated urine samples in pregnant women and infants is feasible. The relatively low correlation across trimesters and between maternal and infant samples highlights the need to collect biospecimens in the assumed sensitive time window. Image 1 • Repeated urine samples were collected and pooled within-subject, within period. • Metabolites of phthalates and DINCH were measured in pooled samples. • Frequencies of detection were overall high. • Pregnancy concentrations of MiBP, MBzP, DEHP and oxo-MINP decreased with time. • Pregnancy concentrations of oh-MiNP and DINCH metabolites increased with time. Relying on a recent cohort (2014–2017) with repeated urine samples collected during pregnancy and infancy, we showed that exposure to phthalates and DINCH is still widespread in the general population. For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for each participant over windows of sensitivity is expected to improve exposure characterization but has rarely been done. We aimed to rely on within-subject pools of repeated urine samples to assess phthalate exposure during pregnancy and infancy. Women of the French SEPAGES mother-child cohort were asked to collect three urine samples per day over seven consecutive days, twice during their pregnancy (approximatively second (T2) and third (T3) trimesters). For their infants they also collected one sample per day during a week at two (M2) and twelve months (M12). Samples were pooled (within-subject, within-period) prior to phthalate and DINCH metabolite concentrations assessment. Number of pooled samples assayed was 477, 456, 152 and 100 for T2, T3, M2 and M12, respectively. All metabolites were detected in more than 95% of the pooled samples except for the two DINCH metabolites (oh- and oxo-MINCH), MMCHP and oh-MPHP at M2 for which detection frequencies ranged between 64% and 88%. Maternal concentrations of MiBP, MBzP, DEHP metabolites and oxo-MiNP decreased between 2014 and 2017, whereas concentrations of oh-MiNP and the two DINCH metabolites increased (Mann-Kendall p-values < 0.05). While improved compared to studies that relied on spot samples, Intraclass Correlation Coefficients for the pregnancy were below 0.40 for most metabolites. Spearman correlation coefficients between pooled samples collected in infancy were lower than those observed during pregnancy, and were all below 0.30. Exposure to emerging phthalate substitutes such as DINCH and DPHP seems widespread among pregnant women and infants. Collecting repeated urine samples in pregnant women and infants is feasible. The relatively low correlation across trimesters and between maternal and infant samples highlights the need to collect biospecimens in the assumed sensitive time window.For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for each participant over windows of sensitivity is expected to improve exposure characterization but has rarely been done. We aimed to rely on within-subject pools of repeated urine samples to assess phthalate exposure during pregnancy and infancy. Women of the French SEPAGES mother-child cohort were asked to collect three urine samples per day over seven consecutive days, twice during their pregnancy (approximatively second (T2) and third (T3) trimesters). For their infants they also collected one sample per day during a week at two (M2) and twelve months (M12). Samples were pooled (within-subject, within-period) prior to phthalate and DINCH metabolite concentrations assessment. Number of pooled samples assayed was 477, 456, 152 and 100 for T2, T3, M2 and M12, respectively. All metabolites were detected in more than 95% of the pooled samples except for the two DINCH metabolites (oh- and oxo-MINCH), MMCHP and oh-MPHP at M2 for which detection frequencies ranged between 64% and 88%. Maternal concentrations of MiBP, MBzP, DEHP metabolites and oxo-MiNP decreased between 2014 and 2017, whereas concentrations of oh-MiNP and the two DINCH metabolites increased (Mann-Kendall p-values < 0.05). While improved compared to studies that relied on spot samples, Intraclass Correlation Coefficients for the pregnancy were below 0.40 for most metabolites. Spearman correlation coefficients between pooled samples collected in infancy were lower than those observed during pregnancy, and were all below 0.30. Exposure to emerging phthalate substitutes such as DINCH and DPHP seems widespread among pregnant women and infants. Collecting repeated urine samples in pregnant women and infants is feasible. The relatively low correlation across trimesters and between maternal and infant samples highlights the need to collect biospecimens in the assumed sensitive time window. For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for each participant over windows of sensitivity is expected to improve exposure characterization but has rarely been done. We aimed to rely on within-subject pools of repeated urine samples to assess phthalate exposure during pregnancy and infancy. Women of the French SEPAGES mother-child cohort were asked to collect three urine samples per day over seven consecutive days, twice during their pregnancy (approximatively second (T2) and third (T3) trimesters). For their infants they also collected one sample per day during a week at two (M2) and twelve months (M12). Samples were pooled (within-subject, within-period) prior to phthalate and DINCH metabolite concentrations assessment. Number of pooled samples assayed was 477, 456, 152 and 100 for T2, T3, M2 and M12, respectively. All metabolites were detected in more than 95% of the pooled samples except for the two DINCH metabolites (oh- and oxo-MINCH), MMCHP and oh-MPHP at M2 for which detection frequencies ranged between 64% and 88%. Maternal concentrations of MiBP, MBzP, DEHP metabolites and oxo-MiNP decreased between 2014 and 2017, whereas concentrations of oh-MiNP and the two DINCH metabolites increased (Mann-Kendall p-values < 0.05). While improved compared to studies that relied on spot samples, Intraclass Correlation Coefficients for the pregnancy were below 0.40 for most metabolites. Spearman correlation coefficients between pooled samples collected in infancy were lower than those observed during pregnancy, and were all below 0.30. Exposure to emerging phthalate substitutes such as DINCH and DPHP seems widespread among pregnant women and infants. Collecting repeated urine samples in pregnant women and infants is feasible. The relatively low correlation across trimesters and between maternal and infant samples highlights the need to collect biospecimens in the assumed sensitive time window. [Display omitted] •Repeated urine samples were collected and pooled within-subject, within period.•Metabolites of phthalates and DINCH were measured in pooled samples.•Frequencies of detection were overall high.•Pregnancy concentrations of MiBP, MBzP, DEHP and oxo-MINP decreased with time.•Pregnancy concentrations of oh-MiNP and DINCH metabolites increased with time. Relying on a recent cohort (2014–2017) with repeated urine samples collected during pregnancy and infancy, we showed that exposure to phthalates and DINCH is still widespread in the general population. |
| ArticleNumber | 117650 |
| Author | Sabaredzovic, Azemira Rolland, Matthieu Philippat, Claire Pin, Isabelle Sakhi, Amrit K. Slama, Rémy Lyon-Caen, Sarah Thomsen, Cathrine |
| Author_xml | – sequence: 1 givenname: Claire surname: Philippat fullname: Philippat, Claire email: claire.philippat@inserm.fr organization: University Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble, France – sequence: 2 givenname: Matthieu orcidid: 0000-0002-8076-5550 surname: Rolland fullname: Rolland, Matthieu email: matthieu.rolland@univ-grenoble-alpes.fr organization: University Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble, France – sequence: 3 givenname: Sarah surname: Lyon-Caen fullname: Lyon-Caen, Sarah email: sarah.lyon-caen@univ-grenoble-alpes.fr organization: University Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble, France – sequence: 4 givenname: Isabelle orcidid: 0000-0002-7529-6999 surname: Pin fullname: Pin, Isabelle email: ipin@chu-grenoble.fr organization: University Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble, France – sequence: 5 givenname: Amrit K. surname: Sakhi fullname: Sakhi, Amrit K. email: AmritKaur.Sakhi@fhi.no organization: Norwegian Institute of Public Health, Oslo, Norway – sequence: 6 givenname: Azemira surname: Sabaredzovic fullname: Sabaredzovic, Azemira email: Azemira.Sabaredzovic@fhi.no organization: Norwegian Institute of Public Health, Oslo, Norway – sequence: 7 givenname: Cathrine surname: Thomsen fullname: Thomsen, Cathrine email: Cathrine.Thomsen@fhi.no organization: Norwegian Institute of Public Health, Oslo, Norway – sequence: 8 givenname: Rémy surname: Slama fullname: Slama, Rémy email: remy.slama@univ-grenoble-alpes.fr organization: University Grenoble Alpes, Inserm, CNRS, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Institute for Advanced Biosciences (IAB), Grenoble, France |
| BackLink | https://inserm.hal.science/inserm-03374698$$DView record in HAL |
| BookMark | eNqFUk1v1DAQjVAR3Rb-AQcfOZDFjh0n4YBULR9baQUcerccZ9J45djBdrbsT-Hf4iUrJHqgp5E1770Zz3tX2YV1FrLsNcFrggl_t1-DPUzOrAtckDUhFS_xs2xF6ormnBXsIlvhgjd5xRpymV2FsMcYM0rpi-ySMkbLkrNV9uu7hxxJ2yGQ3hzR5ELMrYzSIPiZHrMHFB2ahjhIIyOEP9iPt183W6QtksjCA4rHCZDr0ejiAD5XgzYdUm5wPiIP5qjtPXIWPeg4aJuHud2DimmUM-FE8zBBku7Q7LUFFOQ4GQgvs-e9NAFenet1dvf5091mm---fbnd3OxyVRIccwaU86YoFNSMt4zJvu2wKuuO9k3b1RXwuoeiZ30JmNW87ZuKUkkK1UNfYUyvsw-L7DS3I3QKbPTSiMnrUfqjcFKLfztWD-LeHUTNGMM1SwJvF4HhEW17sxPaBvCjwJRWjDf1gST4m_M8737MEKIYdVBgjLTg5iAKTjmjBav409DkYMPSFaoEZQtUeReCh_7vJgSLU1zEXixxEae4iCUuifb-EU3pKKN2p69q8xT5fDlI7hw0eBGUBqug0z75Kzqn_y_wG3Bu4VU |
| CitedBy_id | crossref_primary_10_3390_foods12081697 crossref_primary_10_1016_j_envres_2022_115068 crossref_primary_10_1016_j_envres_2022_114332 crossref_primary_10_1016_j_envres_2024_120555 crossref_primary_10_31011_reaid_2025_v_99_n_3_art_2546 crossref_primary_10_1016_j_envint_2021_106697 crossref_primary_10_1016_j_envint_2023_107840 crossref_primary_10_1080_10643389_2024_2301922 crossref_primary_10_3390_toxics10090538 crossref_primary_10_1016_j_scitotenv_2022_158773 crossref_primary_10_1289_EHP11798 crossref_primary_10_1016_j_fct_2022_112984 crossref_primary_10_1016_j_envint_2024_108763 crossref_primary_10_3390_toxics12090642 crossref_primary_10_1016_j_envint_2024_108584 crossref_primary_10_1093_hropen_hoae018 crossref_primary_10_1016_j_envint_2024_108605 crossref_primary_10_1289_EHP10239 crossref_primary_10_1016_j_jhazmat_2024_136970 crossref_primary_10_1016_j_ijheh_2023_114166 crossref_primary_10_1007_s40572_023_00394_8 crossref_primary_10_1016_j_envres_2025_121173 crossref_primary_10_1021_acs_est_4c13605 crossref_primary_10_1289_EHP13644 crossref_primary_10_1007_s11356_024_32871_4 crossref_primary_10_3390_toxics10020057 crossref_primary_10_1007_s11356_025_36137_5 crossref_primary_10_1016_j_jes_2024_10_026 crossref_primary_10_3390_toxics12100710 crossref_primary_10_1001_jamanetworkopen_2024_12040 |
| Cites_doi | 10.1136/oem.2004.017590 10.1016/j.toxlet.2013.12.012 10.1016/j.ijheh.2019.07.011 10.1289/EHP1994 10.1111/j.1600-0668.2012.00788.x 10.1016/S0013-9351(03)00083-5 10.1007/s00204-012-0990-4 10.1016/j.jchromb.2015.08.040 10.1016/j.ijheh.2013.01.006 10.1007/s40572-019-0227-2 10.1289/ehp.1002231 10.1016/j.envres.2019.03.067 10.1016/j.toxlet.2011.06.010 10.1016/j.scitotenv.2016.02.022 10.1289/ehp.1307569 10.3390/ijerph16203888 10.1016/j.fct.2012.12.004 10.1016/j.ijheh.2018.12.008 10.1016/j.ijheh.2013.08.004 10.1016/j.envres.2016.11.012 10.1016/j.envint.2018.09.046 10.1016/j.ijheh.2020.113518 10.1016/j.envres.2013.05.007 10.1016/j.ijheh.2018.12.011 10.1097/EDE.0000000000001056 10.1097/EDE.0000000000000460 |
| ContentType | Journal Article |
| Copyright | 2021 The Authors Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved. Distributed under a Creative Commons Attribution 4.0 International License 2021 The Authors 2021 |
| Copyright_xml | – notice: 2021 The Authors – notice: Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved. – notice: Distributed under a Creative Commons Attribution 4.0 International License – notice: 2021 The Authors 2021 |
| DBID | 6I. AAFTH AAYXX CITATION 7X8 7S9 L.6 1XC VOOES 5PM |
| DOI | 10.1016/j.envpol.2021.117650 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef MEDLINE - Academic AGRICOLA AGRICOLA - Academic Hyper Article en Ligne (HAL) Hyper Article en Ligne (HAL) (Open Access) PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | AGRICOLA MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Engineering Anatomy & Physiology Environmental Sciences |
| EISSN | 1873-6424 |
| ExternalDocumentID | PMC8444084 oai:HAL:inserm-03374698v1 10_1016_j_envpol_2021_117650 S026974912101232X |
| GroupedDBID | --- --K --M -~X .~1 0R~ 1B1 1RT 1~. 4.4 457 5GY 5VS 6I. 71M 8P~ 9JM AABNK AACTN AAEDT AAEDW AAFTH AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAXUO ABFNM ABFYP ABJNI ABLST ABMAC ABYKQ ACDAQ ACGFS ACIUM ACRLP ADBBV ADEZE AEBSH AEKER AENEX AFKWA AFTJW AFXIZ AGHFR AGUBO AGYEJ AHEUO AHHHB AIEXJ AIKHN AITUG AJOXV AKIFW AKRWK ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BKOJK BLECG BLXMC CS3 DU5 EBS EFJIC EO8 EO9 EP2 EP3 F5P FDB FIRID FNPLU FYGXN G-Q GBLVA IHE J1W KCYFY KOM LW9 LY9 M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 RIG ROL RPZ SAB SCC SCU SDF SDG SDP SES SPCBC SSJ SSZ T5K TWZ WH7 XPP ZMT ~G- 29G 53G 6TJ 9DU AAHBH AAQXK AATTM AAXKI AAYWO AAYXX ABEFU ABWVN ABXDB ACLOT ACRPL ACVFH ADCNI ADMUD ADNMO AEGFY AEIPS AEUPX AFFNX AFJKZ AFPUW AGQPQ AI. AIGII AIIUN AKBMS AKYEP ANKPU APXCP ASPBG AVWKF AZFZN CITATION EFKBS EFLBG EJD FEDTE FGOYB G-2 HLV HMC HVGLF HZ~ OHT R2- SEN SEW VH1 WUQ XOL ~HD 7X8 7S9 L.6 1XC VOOES XJT 5PM |
| ID | FETCH-LOGICAL-c510t-4e366922ce846b44afbd0c58d3f9bd87e68fe2f4f5e0486bf9733a12cfef7003 |
| ISICitedReferencesCount | 31 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000695166900002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0269-7491 1873-6424 |
| IngestDate | Tue Sep 30 16:54:29 EDT 2025 Tue Oct 14 20:53:45 EDT 2025 Thu Oct 02 06:19:57 EDT 2025 Sun Nov 09 11:22:08 EST 2025 Sat Nov 29 07:21:21 EST 2025 Tue Nov 18 22:53:35 EST 2025 Sat Apr 13 16:39:49 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | Pregnancy Infancy Biomarkers Repeated urines Pools Phthalates DINCH |
| Language | English |
| License | This is an open access article under the CC BY-NC-ND license. Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0 This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c510t-4e366922ce846b44afbd0c58d3f9bd87e68fe2f4f5e0486bf9733a12cfef7003 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 PMCID: PMC8444084 |
| ORCID | 0000-0002-8076-5550 0000-0002-7529-6999 0000-0002-4959-6648 |
| OpenAccessLink | https://inserm.hal.science/inserm-03374698 |
| PMID | 34435564 |
| PQID | 2564945107 |
| PQPubID | 23479 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_8444084 hal_primary_oai_HAL_inserm_03374698v1 proquest_miscellaneous_2636432476 proquest_miscellaneous_2564945107 crossref_primary_10_1016_j_envpol_2021_117650 crossref_citationtrail_10_1016_j_envpol_2021_117650 elsevier_sciencedirect_doi_10_1016_j_envpol_2021_117650 |
| PublicationCentury | 2000 |
| PublicationDate | 2021-10-15 |
| PublicationDateYYYYMMDD | 2021-10-15 |
| PublicationDate_xml | – month: 10 year: 2021 text: 2021-10-15 day: 15 |
| PublicationDecade | 2020 |
| PublicationTitle | Environmental pollution (1987) |
| PublicationYear | 2021 |
| Publisher | Elsevier Ltd Elsevier Elsevier Applied Science Publishers |
| Publisher_xml | – name: Elsevier Ltd – name: Elsevier – name: Elsevier Applied Science Publishers |
| References | Gyllenhammar, Glynn, Jönsson, Lindh, Darnerud, Svensson (bib8) 2017; 153 Hauser, Calafat (bib9) 2005; 62 Schmidtkunz, Gries, Weber, Leng, Kolossa-Gehring (bib23) 2019; 222 Philippat, Calafat (bib20) 2020; 110275 Koch, Haller, Weiss, Käfferlein, Stork, Brüning (bib12) 2012; 213 Casas, Basagaña, Sakhi, Haug, Philippat, Granum (bib3) 2018; 121 Schutze, Kolossa-Gehring, Apel, Bruning, Koch (bib24) 2014; 217 Urbancova, Lankova, Sram, Hajslova, Pulkrabova (bib26) 2019; 173 Arbuckle, Fisher, MacPherson, Lang, Provencher, LeBlanc (bib1) 2016; 551–552 Hbm4Eu (bib10) 2018 Warembourg, Basagaña, Seminati, de Bont, Granum, Lyon-Caen (bib30) 2019; 222 Navaranjan, Takaro, Wheeler, Diamond, Shu, Azad (bib18) 2019 Enke, Schleussner, Palmke, Seyfarth, Koch (bib4) 2013; 216 Kasper-Sonnenberg, Koch, Apel, Rüther, Pälmke, Brüning (bib11) 2019 Silva, Jia, Samandar, Preau, Calafat (bib25) 2013; 126 (bib5) 2013 Vernet, Philippat, Calafat, Ye, Lyon-Caen, Siroux (bib28) 2018; 126 Frederiksen, Kuiri-Hanninen, Main, Dunkel, Sankilampi (bib6) 2014; 122 Völkel, Kiranoglu, Schuster, Fromme, HBMnet (bib29) 2014; 225 LaKind, Idri, Naiman, Verner (bib15) 2019; 6 Lyon-Caen, Siroux, Lepeule, Lorimier, Hainaut, Mossuz (bib16) 2019; 16 Perrier, Giorgis-Allemand, Slama, Philippat (bib19) 2016; 27 Carlstedt, Jönsson, Bornehag (bib2) 2013; 23 Koch, Rossbach, Drexler, Angerer (bib13) 2003; 93 Fromme, Gruber, Schuster, Schlummer, Kiranoglu, Bolte (bib7) 2013; 53 Sabaredzovic, Sakhi, Brantsaeter, Thomsen (bib22) 2015; 1002 Preau, Wong, Silva, Needham, Calafat (bib21) 2010; 118 Nakiwala, Vernet, Lyon-Caen, Lavorel, Rolland, Cracowski (bib17) 2020; 227 Watkins, Eliot, Sathyanarayana, Calafat, Yolton, Lanphear (bib31) 2014 Vernet, Philippat, Agier, Calafat, Ye, Lyon-Caen (bib27) 2019; 30 Koch, Schutze, Palmke, Angerer, Bruning (bib14) 2013; 87 Casas (10.1016/j.envpol.2021.117650_bib3) 2018; 121 Lyon-Caen (10.1016/j.envpol.2021.117650_bib16) 2019; 16 Urbancova (10.1016/j.envpol.2021.117650_bib26) 2019; 173 Warembourg (10.1016/j.envpol.2021.117650_bib30) 2019; 222 Sabaredzovic (10.1016/j.envpol.2021.117650_bib22) 2015; 1002 Vernet (10.1016/j.envpol.2021.117650_bib27) 2019; 30 Fromme (10.1016/j.envpol.2021.117650_bib7) 2013; 53 Koch (10.1016/j.envpol.2021.117650_bib14) 2013; 87 Hauser (10.1016/j.envpol.2021.117650_bib9) 2005; 62 Koch (10.1016/j.envpol.2021.117650_bib12) 2012; 213 Watkins (10.1016/j.envpol.2021.117650_bib31) 2014 Nakiwala (10.1016/j.envpol.2021.117650_bib17) 2020; 227 Preau (10.1016/j.envpol.2021.117650_bib21) 2010; 118 Philippat (10.1016/j.envpol.2021.117650_bib20) 2020; 110275 Schmidtkunz (10.1016/j.envpol.2021.117650_bib23) 2019; 222 Frederiksen (10.1016/j.envpol.2021.117650_bib6) 2014; 122 Arbuckle (10.1016/j.envpol.2021.117650_bib1) 2016; 551–552 (10.1016/j.envpol.2021.117650_bib5) 2013 Perrier (10.1016/j.envpol.2021.117650_bib19) 2016; 27 Gyllenhammar (10.1016/j.envpol.2021.117650_bib8) 2017; 153 Enke (10.1016/j.envpol.2021.117650_bib4) 2013; 216 Navaranjan (10.1016/j.envpol.2021.117650_bib18) 2019 Silva (10.1016/j.envpol.2021.117650_bib25) 2013; 126 LaKind (10.1016/j.envpol.2021.117650_bib15) 2019; 6 Hbm4Eu (10.1016/j.envpol.2021.117650_bib10) 2018 Vernet (10.1016/j.envpol.2021.117650_bib28) 2018; 126 Völkel (10.1016/j.envpol.2021.117650_bib29) 2014; 225 Carlstedt (10.1016/j.envpol.2021.117650_bib2) 2013; 23 Schutze (10.1016/j.envpol.2021.117650_bib24) 2014; 217 Koch (10.1016/j.envpol.2021.117650_bib13) 2003; 93 Kasper-Sonnenberg (10.1016/j.envpol.2021.117650_bib11) 2019 |
| References_xml | – volume: 23 start-page: 32 year: 2013 end-page: 39 ident: bib2 article-title: PVC flooring is related to human uptake of phthalates in infants publication-title: Indoor Air – year: 2018 ident: bib10 article-title: Phthalates and Hexamoll DINCH ®Currently available HBM-evidence in Europe and ongoing work in HBM4EU in relation to identified policy publication-title: HBM4EU Workshop of Task 5.5 –phased Action Plan – volume: 121 start-page: 561 year: 2018 end-page: 573 ident: bib3 article-title: Variability of urinary concentrations of non-persistent chemicals in pregnant women and school-aged children publication-title: Environ. Int. – volume: 27 start-page: 378 year: 2016 end-page: 388 ident: bib19 article-title: Within-subject pooling of biological samples to reduce exposure misclassification in biomarker-based studies publication-title: Epidemiology – volume: 225 start-page: 222 year: 2014 end-page: 229 ident: bib29 article-title: Phthalate intake by infants calculated from biomonitoring data publication-title: Toxicol. Lett. – volume: 551–552 start-page: 344 year: 2016 end-page: 356 ident: bib1 article-title: Maternal and early life exposure to phthalates: the Plastics and Personal-care Products use in Pregnancy (P4) study publication-title: Sci. Total Environ. – volume: 217 start-page: 421 year: 2014 end-page: 426 ident: bib24 article-title: Entering markets and bodies: increasing levels of the novel plasticizer Hexamoll(R) DINCH(R) in 24 h urine samples from the German Environmental Specimen Bank publication-title: Int. J. Hyg Environ. Health – volume: 1002 start-page: 343 year: 2015 end-page: 352 ident: bib22 article-title: Determination of 12 urinary phthalate metabolites in Norwegian pregnant women by core-shell high performance liquid chromatography with on-line solid-phase extraction, column switching and tandem mass spectrometry publication-title: Journal of chromatography B, Analytical technologies in the biomedical and life sciences – volume: 16 year: 2019 ident: bib16 article-title: Deciphering the impact of early-life exposures to highly variable environmental factors on foetal and child health: design of SEPAGES couple-child cohort publication-title: Int. J. Environ. Res. Publ. Health – volume: 93 start-page: 177 year: 2003 end-page: 185 ident: bib13 article-title: Internal exposure of the general population to DEHP and other phthalates - determination of secondary and primary phthalate monoester metabolites in urine publication-title: Environ. Res. – year: 2019 ident: bib11 article-title: Time trend of exposure to the phthalate plasticizer substitute DINCH in Germany from 1999 to 2017: biomonitoring data on young adults from the Environmental Specimen Bank (ESB) publication-title: Int. J. Hyg Environ. Health – volume: 122 start-page: 998 year: 2014 end-page: 1005 ident: bib6 article-title: A longitudinal study of urinary phthalate excretion in 58 full-term and 67 preterm infants from birth through 14 months publication-title: Environ. Health Perspect. – volume: 30 start-page: 756 year: 2019 end-page: 767 ident: bib27 article-title: An empirical validation of the within-subject biospecimens pooling approach to minimize exposure misclassification in biomarker-based studies publication-title: Epidemiology – year: 2019 ident: bib18 article-title: Early life exposure to phthalates in the Canadian Healthy Infant Longitudinal Development (CHILD) study: a multi-city birth cohort publication-title: J. Expo. Sci. Environ. Epidemiol. – volume: 153 start-page: 48 year: 2017 end-page: 54 ident: bib8 article-title: Diverging temporal trends of human exposure to bisphenols and plastizisers, such as phthalates, caused by substitution of legacy EDCs? publication-title: Environ. Res. – volume: 53 start-page: 272 year: 2013 end-page: 280 ident: bib7 article-title: Phthalate and di-(2-ethylhexyl) adipate (DEHA) intake by German infants based on the results of a duplicate diet study and biomonitoring data (INES 2) publication-title: Food Chem. Toxicol. – volume: 173 start-page: 342 year: 2019 end-page: 348 ident: bib26 article-title: Urinary metabolites of phthalates and di-iso-nonyl cyclohexane-1,2-dicarboxylate (DINCH)-Czech mothers' and newborns' exposure biomarkers publication-title: Environ. Res. – volume: 87 start-page: 799 year: 2013 end-page: 806 ident: bib14 article-title: Metabolism of the plasticizer and phthalate substitute diisononyl-cyclohexane-1,2-dicarboxylate (DINCH((R))) in humans after single oral doses publication-title: Arch. Toxicol. – volume: 110275 year: 2020 ident: bib20 article-title: Comparison of strategies to efficiently combine repeated urine samples in biomarker-based studies publication-title: Environ. Res. – year: 2014 ident: bib31 article-title: Variability and predictors of urinary concentrations of phthalate metabolites during early childhood – volume: 222 start-page: 446 year: 2019 end-page: 454 ident: bib30 article-title: Exposure to phthalate metabolites, phenols and organophosphate pesticide metabolites and blood pressure during pregnancy publication-title: Int. J. Hyg Environ. Health – volume: 216 start-page: 735 year: 2013 end-page: 742 ident: bib4 article-title: Phthalate exposure in pregnant women and newborns - the urinary metabolite excretion pattern differs distinctly publication-title: Int. J. Hyg Environ. Health – volume: 222 start-page: 419 year: 2019 end-page: 424 ident: bib23 article-title: Internal exposure of young German adults to di(2-propylheptyl) phthalate (DPHP): trends in 24-h urine samples from the German Environmental Specimen Bank 1999-2017 publication-title: Int. J. Hyg Environ. Health – volume: 62 start-page: 806 year: 2005 end-page: 818 ident: bib9 article-title: Phthalates and human health publication-title: Occup. Environ. Med. – volume: 227 start-page: 113518 year: 2020 ident: bib17 article-title: Use of personal care products during pregnancy in relation to urinary concentrations of select phenols: a longitudinal analysis from the SEPAGES feasibility study publication-title: Int. J. Hyg Environ. Health – volume: 126 year: 2013 ident: bib25 article-title: Environmental exposure to the plasticizer 1,2-cyclohexane dicarboxylic acid, diisononyl ester (DINCH) in U.S. adults (2000-2012). - PubMed - NCBI publication-title: Environ. Res. – volume: 118 start-page: 1748 year: 2010 end-page: 1754 ident: bib21 article-title: Variability over 1 Week in the urinary concentrations of metabolites of diethyl phthalate and di(2-ethylhexyl) phthalate among eight adults: an observational study publication-title: Environ. Health Perspect. – volume: 6 start-page: 16 year: 2019 end-page: 21 ident: bib15 article-title: Biomonitoring and nonpersistent chemicals-understanding and addressing variability and exposure misclassification publication-title: Curr Environ Health Rep – volume: 126 year: 2018 ident: bib28 article-title: Within-day, between-day, and between-week variability of urinary concentrations of phenol biomarkers in pregnant women publication-title: Environ. Health Perspect. – volume: 213 start-page: 100 year: 2012 end-page: 106 ident: bib12 article-title: Phthalate exposure during cold plastisol application--a human biomonitoring study publication-title: Toxicol. Lett. – year: 2013 ident: bib5 article-title: Evaluation of New Scientific Evidence Concerning DINP and DIDP in Relation to Entry 52 of Annex XVII to REACH Regulation (EC) No 1907/2006 – volume: 62 start-page: 806 year: 2005 ident: 10.1016/j.envpol.2021.117650_bib9 article-title: Phthalates and human health publication-title: Occup. Environ. Med. doi: 10.1136/oem.2004.017590 – volume: 225 start-page: 222 year: 2014 ident: 10.1016/j.envpol.2021.117650_bib29 article-title: Phthalate intake by infants calculated from biomonitoring data publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2013.12.012 – year: 2019 ident: 10.1016/j.envpol.2021.117650_bib11 article-title: Time trend of exposure to the phthalate plasticizer substitute DINCH in Germany from 1999 to 2017: biomonitoring data on young adults from the Environmental Specimen Bank (ESB) publication-title: Int. J. Hyg Environ. Health doi: 10.1016/j.ijheh.2019.07.011 – volume: 126 year: 2018 ident: 10.1016/j.envpol.2021.117650_bib28 article-title: Within-day, between-day, and between-week variability of urinary concentrations of phenol biomarkers in pregnant women publication-title: Environ. Health Perspect. doi: 10.1289/EHP1994 – volume: 23 start-page: 32 year: 2013 ident: 10.1016/j.envpol.2021.117650_bib2 article-title: PVC flooring is related to human uptake of phthalates in infants publication-title: Indoor Air doi: 10.1111/j.1600-0668.2012.00788.x – volume: 93 start-page: 177 year: 2003 ident: 10.1016/j.envpol.2021.117650_bib13 article-title: Internal exposure of the general population to DEHP and other phthalates - determination of secondary and primary phthalate monoester metabolites in urine publication-title: Environ. Res. doi: 10.1016/S0013-9351(03)00083-5 – volume: 87 start-page: 799 year: 2013 ident: 10.1016/j.envpol.2021.117650_bib14 article-title: Metabolism of the plasticizer and phthalate substitute diisononyl-cyclohexane-1,2-dicarboxylate (DINCH((R))) in humans after single oral doses publication-title: Arch. Toxicol. doi: 10.1007/s00204-012-0990-4 – volume: 1002 start-page: 343 year: 2015 ident: 10.1016/j.envpol.2021.117650_bib22 article-title: Determination of 12 urinary phthalate metabolites in Norwegian pregnant women by core-shell high performance liquid chromatography with on-line solid-phase extraction, column switching and tandem mass spectrometry publication-title: Journal of chromatography B, Analytical technologies in the biomedical and life sciences doi: 10.1016/j.jchromb.2015.08.040 – volume: 216 start-page: 735 year: 2013 ident: 10.1016/j.envpol.2021.117650_bib4 article-title: Phthalate exposure in pregnant women and newborns - the urinary metabolite excretion pattern differs distinctly publication-title: Int. J. Hyg Environ. Health doi: 10.1016/j.ijheh.2013.01.006 – volume: 6 start-page: 16 year: 2019 ident: 10.1016/j.envpol.2021.117650_bib15 article-title: Biomonitoring and nonpersistent chemicals-understanding and addressing variability and exposure misclassification publication-title: Curr Environ Health Rep doi: 10.1007/s40572-019-0227-2 – volume: 118 start-page: 1748 year: 2010 ident: 10.1016/j.envpol.2021.117650_bib21 article-title: Variability over 1 Week in the urinary concentrations of metabolites of diethyl phthalate and di(2-ethylhexyl) phthalate among eight adults: an observational study publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1002231 – volume: 173 start-page: 342 year: 2019 ident: 10.1016/j.envpol.2021.117650_bib26 article-title: Urinary metabolites of phthalates and di-iso-nonyl cyclohexane-1,2-dicarboxylate (DINCH)-Czech mothers' and newborns' exposure biomarkers publication-title: Environ. Res. doi: 10.1016/j.envres.2019.03.067 – volume: 213 start-page: 100 year: 2012 ident: 10.1016/j.envpol.2021.117650_bib12 article-title: Phthalate exposure during cold plastisol application--a human biomonitoring study publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2011.06.010 – volume: 551–552 start-page: 344 year: 2016 ident: 10.1016/j.envpol.2021.117650_bib1 article-title: Maternal and early life exposure to phthalates: the Plastics and Personal-care Products use in Pregnancy (P4) study publication-title: Sci. Total Environ. doi: 10.1016/j.scitotenv.2016.02.022 – volume: 122 start-page: 998 year: 2014 ident: 10.1016/j.envpol.2021.117650_bib6 article-title: A longitudinal study of urinary phthalate excretion in 58 full-term and 67 preterm infants from birth through 14 months publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1307569 – year: 2019 ident: 10.1016/j.envpol.2021.117650_bib18 article-title: Early life exposure to phthalates in the Canadian Healthy Infant Longitudinal Development (CHILD) study: a multi-city birth cohort publication-title: J. Expo. Sci. Environ. Epidemiol. – year: 2014 ident: 10.1016/j.envpol.2021.117650_bib31 – volume: 16 year: 2019 ident: 10.1016/j.envpol.2021.117650_bib16 article-title: Deciphering the impact of early-life exposures to highly variable environmental factors on foetal and child health: design of SEPAGES couple-child cohort publication-title: Int. J. Environ. Res. Publ. Health doi: 10.3390/ijerph16203888 – volume: 53 start-page: 272 year: 2013 ident: 10.1016/j.envpol.2021.117650_bib7 article-title: Phthalate and di-(2-ethylhexyl) adipate (DEHA) intake by German infants based on the results of a duplicate diet study and biomonitoring data (INES 2) publication-title: Food Chem. Toxicol. doi: 10.1016/j.fct.2012.12.004 – volume: 110275 year: 2020 ident: 10.1016/j.envpol.2021.117650_bib20 article-title: Comparison of strategies to efficiently combine repeated urine samples in biomarker-based studies publication-title: Environ. Res. – volume: 222 start-page: 419 year: 2019 ident: 10.1016/j.envpol.2021.117650_bib23 article-title: Internal exposure of young German adults to di(2-propylheptyl) phthalate (DPHP): trends in 24-h urine samples from the German Environmental Specimen Bank 1999-2017 publication-title: Int. J. Hyg Environ. Health doi: 10.1016/j.ijheh.2018.12.008 – volume: 217 start-page: 421 year: 2014 ident: 10.1016/j.envpol.2021.117650_bib24 article-title: Entering markets and bodies: increasing levels of the novel plasticizer Hexamoll(R) DINCH(R) in 24 h urine samples from the German Environmental Specimen Bank publication-title: Int. J. Hyg Environ. Health doi: 10.1016/j.ijheh.2013.08.004 – volume: 153 start-page: 48 year: 2017 ident: 10.1016/j.envpol.2021.117650_bib8 article-title: Diverging temporal trends of human exposure to bisphenols and plastizisers, such as phthalates, caused by substitution of legacy EDCs? publication-title: Environ. Res. doi: 10.1016/j.envres.2016.11.012 – volume: 121 start-page: 561 year: 2018 ident: 10.1016/j.envpol.2021.117650_bib3 article-title: Variability of urinary concentrations of non-persistent chemicals in pregnant women and school-aged children publication-title: Environ. Int. doi: 10.1016/j.envint.2018.09.046 – volume: 227 start-page: 113518 year: 2020 ident: 10.1016/j.envpol.2021.117650_bib17 article-title: Use of personal care products during pregnancy in relation to urinary concentrations of select phenols: a longitudinal analysis from the SEPAGES feasibility study publication-title: Int. J. Hyg Environ. Health doi: 10.1016/j.ijheh.2020.113518 – volume: 126 year: 2013 ident: 10.1016/j.envpol.2021.117650_bib25 article-title: Environmental exposure to the plasticizer 1,2-cyclohexane dicarboxylic acid, diisononyl ester (DINCH) in U.S. adults (2000-2012). - PubMed - NCBI publication-title: Environ. Res. doi: 10.1016/j.envres.2013.05.007 – volume: 222 start-page: 446 year: 2019 ident: 10.1016/j.envpol.2021.117650_bib30 article-title: Exposure to phthalate metabolites, phenols and organophosphate pesticide metabolites and blood pressure during pregnancy publication-title: Int. J. Hyg Environ. Health doi: 10.1016/j.ijheh.2018.12.011 – year: 2018 ident: 10.1016/j.envpol.2021.117650_bib10 article-title: Phthalates and Hexamoll DINCH ®Currently available HBM-evidence in Europe and ongoing work in HBM4EU in relation to identified policy – volume: 30 start-page: 756 year: 2019 ident: 10.1016/j.envpol.2021.117650_bib27 article-title: An empirical validation of the within-subject biospecimens pooling approach to minimize exposure misclassification in biomarker-based studies publication-title: Epidemiology doi: 10.1097/EDE.0000000000001056 – year: 2013 ident: 10.1016/j.envpol.2021.117650_bib5 – volume: 27 start-page: 378 year: 2016 ident: 10.1016/j.envpol.2021.117650_bib19 article-title: Within-subject pooling of biological samples to reduce exposure misclassification in biomarker-based studies publication-title: Epidemiology doi: 10.1097/EDE.0000000000000460 |
| SSID | ssj0004333 |
| Score | 2.5219584 |
| Snippet | For non-persistent chemicals such as phthalates, a single spot urine sample only reflects exposure in the past few hours. Collecting repeated urine samples for... |
| SourceID | pubmedcentral hal proquest crossref elsevier |
| SourceType | Open Access Repository Aggregation Database Enrichment Source Index Database Publisher |
| StartPage | 117650 |
| SubjectTerms | Biochemistry Biochemistry, Molecular Biology Biomarkers DINCH Ecology, environment exposure characterization Health Infancy Life Sciences metabolites Phthalates pollution Pools Pregnancy Repeated urines Santé publique et épidémiologie urine |
| Title | Pre- and early post-natal exposure to phthalates and DINCH in a new type of mother-child cohort relying on within-subject pools of repeated urine samples |
| URI | https://dx.doi.org/10.1016/j.envpol.2021.117650 https://www.proquest.com/docview/2564945107 https://www.proquest.com/docview/2636432476 https://inserm.hal.science/inserm-03374698 https://pubmed.ncbi.nlm.nih.gov/PMC8444084 |
| Volume | 287 |
| WOSCitedRecordID | wos000695166900002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1873-6424 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0004333 issn: 0269-7491 databaseCode: AIEXJ dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9swDBb6GIruMGztinWPQgO2XQoVqaVY1jHoWqRbUQRYD7kZtiMjCVLZiJ2g_Sn7tyMlO7FXbO0OuxiJH7Ed8qMoivxIyKcErGJX6phxT0kmYslZJKVmggtPajWSI2ULha_k9XUwHKrBxuZOXQuznEljgrs7lf9XUcM-EDaWzv6DuFc_CjvgMwgdtiB22D5J8IO5ZnZJQFvu4jwrSmZsjxB9B19wwQD8zXxcjqMZOpouGRkm932MfUTYY9wFZnHl3dZnMVvxfYy9dOclVr_Y0qjMFYBPDCsW8dRSIGeZ42Ke6xxMPLiyGMrXx0WEFMRFaxFgXV-HpWDYb7lSxOC3-ISL-OSRS0-ZRY1sXSQUr_IybdvyiV6s8ovuM8POImdTW1HvgSNNuCwiXHLRzaiHZ9PuXN2nC8VVfkPDWnq-YlK41l8n2lnzAFQPJliiae49N8A_GDpcFGN6os0S3voEb4or2r7jxW0oTn5rNYcL8DS7joK9zePd7_0IB18vwqvL6-_to43kx37vCrYTA5p3yzqcS2zluYR5_LYnuwrs83bv8nz4bV3jyzl38UL3mnUZqM1VfPjMu2SnfsA_eVybY0z9bcyr2lnBDTfr5iV5Uc2PaM_p9Suyoc0e2e-BAme39_QLtRnLdilojzxvkGnukYOWTtFq0Cr2yU9EBAVFoRYRdI0IWiOClhldI8KeaxFBJ4ZGFBBBERE0S2kTEdQhglaIoJmhbURQiwi8rEYEtYigFSJek5uL85uzPqs6krAExq6SCc19X3leosFtj4WI0njUSbrBiKcqHgVS-0GqvVSkXY1UlnGqJOfRqZekOpUwfh6QLZMZ_YZQlZwCnGLVibG421OxTGSKzRQE-Msj0T0kvBZamFRs_dg0ZhbWaZnT0Ek9RKmHTuqHhK2uyh1bzSPny1ofwsrjdp50CKh45MrPIJPVTZCkHjQ6dPocrvX5kHysFSyEgQtXIyOjs0URwlxLKAF_q_zLOT73kTJU-vCkLe1s3bl9xEzGliY_EEJ0AvH2iU_6juyuDc17slXOF_oDeZYsy0kxPyKbchgcVaD8BeRlM8o |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pre-+and+early+post-natal+exposure+to+phthalates+and+DINCH+in+a+new+type+of+mother-child+cohort+relying+on+within-subject+pools+of+repeated+urine+samples&rft.jtitle=Environmental+pollution+%281987%29&rft.au=Philippat%2C+Claire&rft.au=Rolland%2C+Matthieu&rft.au=Lyon-Caen%2C+Sarah&rft.au=Pin%2C+Isabelle&rft.date=2021-10-15&rft.pub=Elsevier&rft.issn=0269-7491&rft.eissn=1873-6424&rft.volume=287&rft_id=info:doi/10.1016%2Fj.envpol.2021.117650&rft_id=info%3Apmid%2F34435564&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=oai%3AHAL%3Ainserm-03374698v1 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0269-7491&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0269-7491&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0269-7491&client=summon |