The current practice of cytoreductive surgery and HIPEC for colorectal peritoneal metastases: Results of a worldwide web-based survey of the Peritoneal Surface Oncology Group International (PSOGI)

At present, selected patients with resectable colorectal peritoneal metastases (CRC-PM) are increasingly treated with a combination therapy of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). The aim of this study was to investigate the current worldwide practice. H...

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Veröffentlicht in:European journal of surgical oncology Jg. 44; H. 12; S. 1942 - 1948
Hauptverfasser: Bushati, M., Rovers, K.P., Sommariva, A., Sugarbaker, P.H., Morris, D.L., Yonemura, Y., Quadros, C.A., Somashekhar, S.P., Ceelen, W., Dubé, P., Li, Y., Verwaal, V.J., Glehen, O., Piso, P., Spiliotis, J., Teo, M.C.C., González-Moreno, S., Cashin, P.H., Lehmann, K., Deraco, M., Moran, B., de Hingh, I.H.J.T.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Elsevier Ltd 01.12.2018
Schlagworte:
Colorectal Neoplasms - pathology
Colorectal peritoneal metastases
Combined Modality Therapy
Cytoreduction Surgical Procedures - methods
Cytoreductive surgery
Humans
Hyperthermia, Induced - methods
Hyperthermic intraperitoneal chemotherapy
Internet
Peritoneal Neoplasms - secondary
Peritoneal Neoplasms - therapy
Practice Patterns, Physicians' - statistics & numerical data
Surveys and Questionnaires
Treatment Outcome
CRS and HIPEC
PSOGI
CRC-PM
BSA
EPIC
Cytoreductive surgery
PCI
IP
Hyperthermic intraperitoneal chemotherapy
MDT
Colorectal peritoneal metastases
ISSN:0748-7983, 1532-2157, 1532-2157
Online-Zugang:Volltext
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Zusammenfassung:At present, selected patients with resectable colorectal peritoneal metastases (CRC-PM) are increasingly treated with a combination therapy of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). The aim of this study was to investigate the current worldwide practice. HIPEC experts from 19 countries were invited through the Peritoneal Surface Oncology Group International (PSOGI) to complete an online survey concerning their personal expertise and current hospital and countrywide practice. It is estimated that currently more than 3800 patients with CRC-PM (synchronous and metachronous) are annually treated with CRS and HIPEC in 430 centers. Integration of CRS and HIPEC in national guidelines varies, resulting in large treatment disparities between countries. Amongst the experts, there was general agreement on issues related to indication, surgical technique and follow up but less on systemic chemotherapy or proactive strategies. This international survey demonstrates that CRS and HIPEC is now performed on a large scale for CRC-PM patients. Variation in treatment may result in heterogeneity in surgical and oncological outcomes, emphasising the necessity to reach consensus on several issues of this comprehensive procedure. Future initiatives directed at achieving an international consensus statement are needed.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0748-7983
1532-2157
1532-2157
DOI:10.1016/j.ejso.2018.07.003