Beneficial effects of adenosine triphosphate-sensitive K+ channel opener on liver ischemia/reperfusion injury

To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury. Wistar male rats underwent partial liver ischemia performed by clamping the pedicle from the medium and left anterior lateral segments for 1 h under mechanical ventilation. They were divided into 3 groups: Co...

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Bibliographic Details
Published in:	World journal of gastroenterology : WJG Vol. 20; no. 41; p. 15319
Main Authors:	Nogueira, Mateus Antunes, Coelho, Ana Maria Mendonça, Sampietre, Sandra Nassa, Patzina, Rosely Antunes, Pinheiro da Silva, Fabiano, D'Albuquerque, Luiz Augusto Carneiro, Machado, Marcel Cerqueira Cesar
Format:	Journal Article
Language:	English
Published:	United States 07.11.2014
Subjects:	Animals Biomarkers - blood Diazoxide - pharmacology Disease Models, Animal Inflammation - metabolism Inflammation - prevention & control Inflammation Mediators - blood Liver - blood supply Liver - drug effects Liver - metabolism Liver - pathology Liver Diseases - blood Liver Diseases - pathology Liver Diseases - prevention & control Male Mitochondria, Liver - drug effects Mitochondria, Liver - metabolism Oxidative Stress - drug effects Potassium Channels - agonists Potassium Channels - metabolism Rats, Wistar Reperfusion Injury - blood Reperfusion Injury - pathology Reperfusion Injury - prevention & control Signal Transduction - drug effects Time Factors Mitochondrial ATP-sensitive potassium channel K+ channel opener Diazoxide Liver ischemia/reperfusion Liver mitochondria
ISSN:	2219-2840, 2219-2840
Online Access:	Get more information
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