Gating of social reward by oxytocin in the ventral tegmental area

The reward generated by social interactions is critical for promoting prosocial behaviors. Here we present evidence that oxytocin (OXT) release in the ventral tegmental area (VTA), a key node of the brain's reward circuitry, is necessary to elicit social reward. During social interactions, acti...

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Bibliographic Details

Published in:	Science (American Association for the Advancement of Science) Vol. 357; no. 6358; p. 1406
Main Authors:	Hung, Lin W, Neuner, Sophie, Polepalli, Jai S, Beier, Kevin T, Wright, Matthew, Walsh, Jessica J, Lewis, Eastman M, Luo, Liqun, Deisseroth, Karl, Dölen, Gül, Malenka, Robert C
Format:	Journal Article
Language:	English
Published:	United States 29.09.2017
Subjects:	Animals Dopaminergic Neurons - physiology Integrases Interpersonal Relations Mice Mice, Knockout Oxytocin - genetics Oxytocin - secretion Paraventricular Hypothalamic Nucleus - cytology Presynaptic Terminals - physiology Reward Social Behavior Ventral Tegmental Area - secretion
ISSN:	1095-9203, 1095-9203
Online Access:	Get more information
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