Lower FGFR2 mRNA Expression and Higher Levels of FGFR2 IIIc in HER2-Positive Breast Cancer

Fibroblast growth factor receptor 2 (FGFR2) has been associated with breast cancer. We performed in silico analyses to investigate the FGFR2 mRNA expression and splice variants associated with breast cancer subtypes. Online databases, including cBioPortal and TCGA SpliceSeq, were used to examine the...

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Veröffentlicht in:	Biology (Basel, Switzerland) Jg. 13; H. 11; S. 920
Hauptverfasser:	Dix-Peek, Thérèse, Dickens, Caroline, Valcárcel, Juan, Duarte, Raquel A. B.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 01.11.2024 MDPI
Schlagworte:	alternative splicing Apoptosis Breast cancer Cancer therapies Clinical outcomes ErbB-2 protein Estrogen Estrogens FGFR2 Fibroblast growth factor receptor 2 Fibroblast growth factors Gene expression Genes Genetic aspects Genome-wide association studies Genomes Genomics Growth factors IIIb IIIc Immunohistochemistry Kinases Ligands Malignancy Medical prognosis Messenger RNA mRNA expression Proteins Tumors South Africa Puerto Rico alternative splicing IIIc breast cancer IIIb HER2 FGFR2 mRNA expression
ISSN:	2079-7737, 2079-7737
Online-Zugang:	Volltext
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