Age-Dependent Reductions in the Level of Glial Fibrillary Acidic Protein in the Prefrontal Cortex in Major Depression

The density of glial cells is reduced in certain layers of the dorsolateral prefrontal cortex in major depressive disorder (MDD). Moreover, there are reductions in the packing density of glial fibrillary acidic protein (GFAP) immunoreactive astrocytes in the same cortical layers in younger subjects...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) Jg. 29; H. 11; S. 2088 - 2096
Hauptverfasser:	Si, Xiaohong, Miguel-Hidalgo, Jose Javier, O'Dwyer, Gillian, Stockmeier, Craig A, Rajkowska, Grazyna
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York, NY Nature Publishing 01.11.2004 Nature Publishing Group
Schlagworte:	Adult Age Factors Aged Aged, 80 and over Biological and medical sciences Depressive Disorder, Major - metabolism Depressive Disorder, Major - pathology Female Glial Fibrillary Acidic Protein - metabolism Humans Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Prefrontal Cortex - metabolism Prefrontal Cortex - pathology Mood disorder Frontal lobe Senescence Neuroglia Glial fibrillary acidic protein Depression Astrocyte Prefrontal cortex glia Western blotting aging astrocytes Age
ISSN:	0893-133X, 1740-634X
Online-Zugang:	Volltext
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