Genome-wide DNA methylation of lesional and peri-lesional skin in vitiligo: a comparative and integrated analysis of multi-omics in Chinese population

Several studies have emphasized the role of DNA methylation in vitiligo. However, its profile in human skin of individuals with vitiligo remains unknown. Here, we aimed to study the DNA methylation profile of vitiligo using pairwise comparisons of lesions, peri-lesions, and healthy skin. We investig...

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Vydáno v:	Human genetics Ročník 143; číslo 2; s. 137 - 149
Hlavní autoři:	Liu, Lin, Xue, Yuzhou, Li, Yuxin, Chen, Yangmei, Pan, Xingyu, Huang, Yujing, Chen, Tingqiao, Zhong, Judan, Shao, Xinyi, Pu, Yihuan, Chen, Jin
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2024 Springer Springer Nature B.V
Témata:	Biomedical and Life Sciences Biomedicine Cell division Cell interactions circadian rhythm Circadian rhythms Comparative analysis data collection DNA DNA methylation Extracellular matrix fatty acid metabolism Fatty acids Gene Function Genes Genomes Genomics Human Genetics Keratinocytes Melanocytes Metabolic Diseases Methylation Molecular Medicine multiomics Original Investigation pathogenesis peroxidase Pigmentation Population studies RNA Skin skin (animal) Skin diseases synapse Synapses therapeutics transcriptome Transcriptomes Vitiligo
ISSN:	0340-6717, 1432-1203, 1432-1203
On-line přístup:	Získat plný text
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