Physoxia alters human mesenchymal stem cell secretome

The human mesenchymal stem cell (hMSC) secretome has pleiotropic effects which underpin their therapeutic potential. hMSC serum-free conditioned media (SFCM) has been determined to contain a variety of cytokines with roles in regeneration and suppression of inflammation. Physiological oxygen (physox...

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Bibliographic Details
Published in:	Journal of tissue engineering Vol. 12; p. 20417314211056132
Main Authors:	Merkhan, Marwan M, Shephard, Matthew T, Forsyth, Nicholas R
Format:	Journal Article
Language:	English
Published:	London, England SAGE Publications 2021 Sage Publications Ltd SAGE Publishing
Subjects:	Adiponectin Biomolecules Colony-stimulating factor Cytokines Detection limits Epidermal growth factor Granulocyte colony-stimulating factor Growth factors Hypoxia Interferon Interleukin 1 Interleukin 10 Interleukin 2 Interleukin 4 Leukocytes (granulocytic) Mesenchymal stem cells Nerve growth factor Original Oxygen Pattern analysis Protein folding Proteins RANTES Regeneration Secretome Stem cells Tumor necrosis factor-α Vascular endothelial growth factor Workstations mesenchymal stem cell physoxia Secretome
ISSN:	2041-7314, 2041-7314
Online Access:	Get full text
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