Posttranscriptional Gene Regulation by Long Noncoding RNA

Eukaryotic cells transcribe a vast number of noncoding RNA species. Among them, long noncoding RNAs (lncRNAs) have been widely implicated in the regulation of gene transcription. However, examples of posttranscriptional gene regulation by lncRNAs are emerging. Through extended base-pairing, lncRNAs...

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Veröffentlicht in:	Journal of molecular biology Jg. 425; H. 19; S. 3723 - 3730
Hauptverfasser:	Yoon, Je-Hyun, Abdelmohsen, Kotb, Gorospe, Myriam
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier Ltd 09.10.2013
Schlagworte:	Cell Line, Tumor eukaryotic cells gene expression genes genetics human diseases Humans lincRNA lncRNA messenger RNA metabolism microRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism mRNA turnover non-coding RNA RNA precursors RNA Processing, Post-Transcriptional RNA Splicing RNA Stability RNA, Long Noncoding RNA, Messenger RNA, Messenger - genetics RNA, Messenger - metabolism RNA-binding protein RNA-binding proteins RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism transcription (genetics) translation (genetics) translational regulation BACE1 pre-mRNA RNA-binding protein lncRNA sno-lncRNA mRNA turnover lincRNA PABP translational regulation poly(A)-binding protein β amyloid-cleaving enzyme 1 precursor mRNA small nucleolar lncRNA long noncoding RNA
ISSN:	0022-2836, 1089-8638, 1089-8638
Online-Zugang:	Volltext
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