Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage

Intracerebral hemorrhage (ICH) can be divided into a primary and secondary phase. In the primary phase, hematoma volume is evaluated and therapies are focused on reducing hematoma expansion. In the secondary, neuroprotective phase, complex systemic inflammatory cascades, direct cellular toxicity, an...

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Vydáno v:	Therapeutic advances in neurological disorders Ročník 14; s. 17562864211049208
Hlavní autoři:	Bautista, Wendy, Adelson, P. David, Bicher, Nathan, Themistocleous, Marios, Tsivgoulis, Georgios, Chang, Jason J.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London, England SAGE Publications 2021 SAGE PUBLICATIONS, INC SAGE Publishing
Témata:	Blood pressure Blood-brain barrier Cell activation Clinical trials Edema Endothelins Hematoma Hemorrhage Hemostasis Inflammation Macrophages Matrix metalloproteinase Metalloproteinase Neuroprotection Review Sphingosine 1-phosphate Toxicity Transient receptor potential proteins intracerebral hemorrhage secondary injury vasogenic edema perihematomal edema neuroprotection
ISSN:	1756-2864, 1756-2856, 1756-2864
On-line přístup:	Získat plný text
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