Pigmentation effects of blue light irradiation on skin and how to protect against them
Background Visible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the clear effect of blue light on photoageing are still scarce, and so far, most studies have focused on broad‐spectrum visible light...
Uložené v:
| Vydané v: | International journal of cosmetic science Ročník 42; číslo 4; s. 399 - 406 |
|---|---|
| Hlavní autori: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
England
Wiley Subscription Services, Inc
01.08.2020
John Wiley and Sons Inc |
| Predmet: | |
| ISSN: | 0142-5463, 1468-2494, 1468-2494 |
| On-line prístup: | Získať plný text |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | Background
Visible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the clear effect of blue light on photoageing are still scarce, and so far, most studies have focused on broad‐spectrum visible light. Although there is evidence for increased skin pigmentation, the underlying mechanisms of photoageing in vivo are still unclear. Furthermore, there is still a need for active ingredients to significantly protect against blue light‐induced hyperpigmentation in vivo.
Our study had two aims: to detect visible changes in skin pigmentation following repeated irradiation of the skin with LED‐based blue light and to reduce pigmentation using suitable active ingredients.
Method
We conducted a randomized, double‐blind and placebo‐controlled clinical study on 33 female volunteers with skin phototypes III and IV. We used a repetitive blue light (4 × 60 J cm−2, 450 nm) irradiation protocol on the volunteers’ inner forearms. Using hyperspectral imaging, we assessed chromophore status. In addition, we took chromameter measurements and photographs to assess visible hyperpigmentation.
Results
We measured significant changes in chromophore status (P < 0.001 vs baseline), that is of melanin, haemoglobin and oxygen saturation, immediately after blue light irradiation. In addition, we found visible skin colour changes which were expressed by a significant decrease in ITA° values (delta ITA° = −16.89, P < 0.001 vs baseline for the placebo group) and an increase in a* (delta a* = +3.37, P < 0.001 vs baseline for the placebo group) 24 h post‐irradiation. Hyperpigmentation and skin reddening were mitigated by both a formulation containing 3% of a microalgal product and a formulation containing 3% niacinamide.
Conclusion
Our study sets out an efficient and robust protocol for investigating both blue light‐induced cutaneous alterations, such as changes in skin chromophores, and signs of photoageing, such as hyperpigmentation. Moreover, we have shown evidence that both an extract of the microalga Scenedesmus rubescens and niacinamide (vitamin B3) have the potential to protect against blue light‐induced hyperpigmentation.
Resume
Contexte
La lumière visible, en particulier la lumière bleue, a été identifiée comme un facteur supplémentaire du photo‐vieillissement cutané. Cependant, les études cliniques, démontrant l’effet réel de la lumière bleue sur le photo‐vieillissement, sont encore rares et jusqu’à présent, la plupart des études portaient sur l’influence de la lumière visible à large spectre. Bien qu’il y ait des preuves concernant l’effet sur la pigmentation de peau, les mécanismes sous‐jacents du photo‐vieillissement in vivo sont encore peu clairs. De plus, le besoin d’ingrédients actifs protégeant de manière significative en in vivo contre l’hyperpigmentation induite par la lumière bleu est toujours présent.
Notre étude a eu deux objectifs
Détecter des changements visibles dans la pigmentation de la peau à la suite d’une irradiation répétée avec de la lumière bleue à base de LED, et réduire la pigmentation à l’aide d’ingrédients actifs adaptés.
Méthode
Nous avons mené une étude clinique randomisée, à l’aveugle et controlée avec un placebo sur 33 volontaires féminins de phototypes de peau III et IV. Nous avons défini un protocole d’irradiation répétitif à lumière bleue (4 x 60 J cm‐2, 450 nm) sur les avant‐bras intérieurs des volontaires. En utilisant l’imagerie hyperspectrale nous avons évalué l’état de chromophore. En outre, nous avons pris des mesures de couleur et des photographies pour évaluer l’hyperpigmentation de manière visuelle.
Résultats
Nous avons mesuré des changements significatifs dans le statut de chromophore (p<0.001 par rapport au statut initial), par exemple au niveau de la mélanine, de l’hémoglobine et de la saturation en oxygène, immédiatement après l’irradiation à lumière bleue. De plus, nous avons constaté des changements visibles de couleur de la peau qui ont été exprimés par une diminution significative des valeurs ITA° (delta ITA° valeurs = ‐16.89, p<0.001 par rapport au statut initial pour le groupe placebo), et une augmentation de a* (delta a* = +3.37, p <0.001 par rapport au statut initial pour le groupe placebo) 24 heures après l’irradiation. L’hyperpigmentation et les rougeurs de la peau ont été atténués par une formulation contenant 3% d’un extrait d’algue ainsi que par une formulation contenant 3% de niacinamide.
Conclusion
Notre étude a établi un protocole efficace et robuste pour étudier à la fois les altérations cutanées induites par la lumière bleue, telles que les changements dans les chromophores de la peau, ainsi que les signes de photo‐vieillissement, tels que l’hyperpigmentation. Enfin, nous avons prouvé qu’un extrait de l’algue Scenedesmus rubescens et la niacinamide (vitamine B3) avaient le potentiel de protéger contre l’hyperpigmentation induite par la lumière bleue.
We provide here a method to study blue light induced changes in skin in vivo. We show that an algal extract and niacinamide can mitigate blue light induced visible pigmentation and skin reddening. |
|---|---|
| AbstractList | Visible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the clear effect of blue light on photoageing are still scarce, and so far, most studies have focused on broad-spectrum visible light. Although there is evidence for increased skin pigmentation, the underlying mechanisms of photoageing in vivo are still unclear. Furthermore, there is still a need for active ingredients to significantly protect against blue light-induced hyperpigmentation in vivo. Our study had two aims: to detect visible changes in skin pigmentation following repeated irradiation of the skin with LED-based blue light and to reduce pigmentation using suitable active ingredients.
We conducted a randomized, double-blind and placebo-controlled clinical study on 33 female volunteers with skin phototypes III and IV. We used a repetitive blue light (4 × 60 J cm
, 450 nm) irradiation protocol on the volunteers' inner forearms. Using hyperspectral imaging, we assessed chromophore status. In addition, we took chromameter measurements and photographs to assess visible hyperpigmentation.
We measured significant changes in chromophore status (P < 0.001 vs baseline), that is of melanin, haemoglobin and oxygen saturation, immediately after blue light irradiation. In addition, we found visible skin colour changes which were expressed by a significant decrease in ITA° values (delta ITA° = -16.89, P < 0.001 vs baseline for the placebo group) and an increase in a* (delta a* = +3.37, P < 0.001 vs baseline for the placebo group) 24 h post-irradiation. Hyperpigmentation and skin reddening were mitigated by both a formulation containing 3% of a microalgal product and a formulation containing 3% niacinamide.
Our study sets out an efficient and robust protocol for investigating both blue light-induced cutaneous alterations, such as changes in skin chromophores, and signs of photoageing, such as hyperpigmentation. Moreover, we have shown evidence that both an extract of the microalga Scenedesmus rubescens and niacinamide (vitamin B3) have the potential to protect against blue light-induced hyperpigmentation. Background Visible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the clear effect of blue light on photoageing are still scarce, and so far, most studies have focused on broad‐spectrum visible light. Although there is evidence for increased skin pigmentation, the underlying mechanisms of photoageing in vivo are still unclear. Furthermore, there is still a need for active ingredients to significantly protect against blue light‐induced hyperpigmentation in vivo. Our study had two aims: to detect visible changes in skin pigmentation following repeated irradiation of the skin with LED‐based blue light and to reduce pigmentation using suitable active ingredients. Method We conducted a randomized, double‐blind and placebo‐controlled clinical study on 33 female volunteers with skin phototypes III and IV. We used a repetitive blue light (4 × 60 J cm−2, 450 nm) irradiation protocol on the volunteers’ inner forearms. Using hyperspectral imaging, we assessed chromophore status. In addition, we took chromameter measurements and photographs to assess visible hyperpigmentation. Results We measured significant changes in chromophore status (P < 0.001 vs baseline), that is of melanin, haemoglobin and oxygen saturation, immediately after blue light irradiation. In addition, we found visible skin colour changes which were expressed by a significant decrease in ITA° values (delta ITA° = −16.89, P < 0.001 vs baseline for the placebo group) and an increase in a* (delta a* = +3.37, P < 0.001 vs baseline for the placebo group) 24 h post‐irradiation. Hyperpigmentation and skin reddening were mitigated by both a formulation containing 3% of a microalgal product and a formulation containing 3% niacinamide. Conclusion Our study sets out an efficient and robust protocol for investigating both blue light‐induced cutaneous alterations, such as changes in skin chromophores, and signs of photoageing, such as hyperpigmentation. Moreover, we have shown evidence that both an extract of the microalga Scenedesmus rubescens and niacinamide (vitamin B3) have the potential to protect against blue light‐induced hyperpigmentation. Resume Contexte La lumière visible, en particulier la lumière bleue, a été identifiée comme un facteur supplémentaire du photo‐vieillissement cutané. Cependant, les études cliniques, démontrant l’effet réel de la lumière bleue sur le photo‐vieillissement, sont encore rares et jusqu’à présent, la plupart des études portaient sur l’influence de la lumière visible à large spectre. Bien qu’il y ait des preuves concernant l’effet sur la pigmentation de peau, les mécanismes sous‐jacents du photo‐vieillissement in vivo sont encore peu clairs. De plus, le besoin d’ingrédients actifs protégeant de manière significative en in vivo contre l’hyperpigmentation induite par la lumière bleu est toujours présent. Notre étude a eu deux objectifs Détecter des changements visibles dans la pigmentation de la peau à la suite d’une irradiation répétée avec de la lumière bleue à base de LED, et réduire la pigmentation à l’aide d’ingrédients actifs adaptés. Méthode Nous avons mené une étude clinique randomisée, à l’aveugle et controlée avec un placebo sur 33 volontaires féminins de phototypes de peau III et IV. Nous avons défini un protocole d’irradiation répétitif à lumière bleue (4 x 60 J cm‐2, 450 nm) sur les avant‐bras intérieurs des volontaires. En utilisant l’imagerie hyperspectrale nous avons évalué l’état de chromophore. En outre, nous avons pris des mesures de couleur et des photographies pour évaluer l’hyperpigmentation de manière visuelle. Résultats Nous avons mesuré des changements significatifs dans le statut de chromophore (p<0.001 par rapport au statut initial), par exemple au niveau de la mélanine, de l’hémoglobine et de la saturation en oxygène, immédiatement après l’irradiation à lumière bleue. De plus, nous avons constaté des changements visibles de couleur de la peau qui ont été exprimés par une diminution significative des valeurs ITA° (delta ITA° valeurs = ‐16.89, p<0.001 par rapport au statut initial pour le groupe placebo), et une augmentation de a* (delta a* = +3.37, p <0.001 par rapport au statut initial pour le groupe placebo) 24 heures après l’irradiation. L’hyperpigmentation et les rougeurs de la peau ont été atténués par une formulation contenant 3% d’un extrait d’algue ainsi que par une formulation contenant 3% de niacinamide. Conclusion Notre étude a établi un protocole efficace et robuste pour étudier à la fois les altérations cutanées induites par la lumière bleue, telles que les changements dans les chromophores de la peau, ainsi que les signes de photo‐vieillissement, tels que l’hyperpigmentation. Enfin, nous avons prouvé qu’un extrait de l’algue Scenedesmus rubescens et la niacinamide (vitamine B3) avaient le potentiel de protéger contre l’hyperpigmentation induite par la lumière bleue. We provide here a method to study blue light induced changes in skin in vivo. We show that an algal extract and niacinamide can mitigate blue light induced visible pigmentation and skin reddening. We provide here a method to study blue light induced changes in skin in vivo. We show that an algal extract and niacinamide can mitigate blue light induced visible pigmentation and skin reddening. Visible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the clear effect of blue light on photoageing are still scarce, and so far, most studies have focused on broad-spectrum visible light. Although there is evidence for increased skin pigmentation, the underlying mechanisms of photoageing in vivo are still unclear. Furthermore, there is still a need for active ingredients to significantly protect against blue light-induced hyperpigmentation in vivo. Our study had two aims: to detect visible changes in skin pigmentation following repeated irradiation of the skin with LED-based blue light and to reduce pigmentation using suitable active ingredients.BACKGROUNDVisible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the clear effect of blue light on photoageing are still scarce, and so far, most studies have focused on broad-spectrum visible light. Although there is evidence for increased skin pigmentation, the underlying mechanisms of photoageing in vivo are still unclear. Furthermore, there is still a need for active ingredients to significantly protect against blue light-induced hyperpigmentation in vivo. Our study had two aims: to detect visible changes in skin pigmentation following repeated irradiation of the skin with LED-based blue light and to reduce pigmentation using suitable active ingredients.We conducted a randomized, double-blind and placebo-controlled clinical study on 33 female volunteers with skin phototypes III and IV. We used a repetitive blue light (4 × 60 J cm-2 , 450 nm) irradiation protocol on the volunteers' inner forearms. Using hyperspectral imaging, we assessed chromophore status. In addition, we took chromameter measurements and photographs to assess visible hyperpigmentation.METHODWe conducted a randomized, double-blind and placebo-controlled clinical study on 33 female volunteers with skin phototypes III and IV. We used a repetitive blue light (4 × 60 J cm-2 , 450 nm) irradiation protocol on the volunteers' inner forearms. Using hyperspectral imaging, we assessed chromophore status. In addition, we took chromameter measurements and photographs to assess visible hyperpigmentation.We measured significant changes in chromophore status (P < 0.001 vs baseline), that is of melanin, haemoglobin and oxygen saturation, immediately after blue light irradiation. In addition, we found visible skin colour changes which were expressed by a significant decrease in ITA° values (delta ITA° = -16.89, P < 0.001 vs baseline for the placebo group) and an increase in a* (delta a* = +3.37, P < 0.001 vs baseline for the placebo group) 24 h post-irradiation. Hyperpigmentation and skin reddening were mitigated by both a formulation containing 3% of a microalgal product and a formulation containing 3% niacinamide.RESULTSWe measured significant changes in chromophore status (P < 0.001 vs baseline), that is of melanin, haemoglobin and oxygen saturation, immediately after blue light irradiation. In addition, we found visible skin colour changes which were expressed by a significant decrease in ITA° values (delta ITA° = -16.89, P < 0.001 vs baseline for the placebo group) and an increase in a* (delta a* = +3.37, P < 0.001 vs baseline for the placebo group) 24 h post-irradiation. Hyperpigmentation and skin reddening were mitigated by both a formulation containing 3% of a microalgal product and a formulation containing 3% niacinamide.Our study sets out an efficient and robust protocol for investigating both blue light-induced cutaneous alterations, such as changes in skin chromophores, and signs of photoageing, such as hyperpigmentation. Moreover, we have shown evidence that both an extract of the microalga Scenedesmus rubescens and niacinamide (vitamin B3) have the potential to protect against blue light-induced hyperpigmentation.CONCLUSIONOur study sets out an efficient and robust protocol for investigating both blue light-induced cutaneous alterations, such as changes in skin chromophores, and signs of photoageing, such as hyperpigmentation. Moreover, we have shown evidence that both an extract of the microalga Scenedesmus rubescens and niacinamide (vitamin B3) have the potential to protect against blue light-induced hyperpigmentation. BackgroundVisible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the clear effect of blue light on photoageing are still scarce, and so far, most studies have focused on broad‐spectrum visible light. Although there is evidence for increased skin pigmentation, the underlying mechanisms of photoageing in vivo are still unclear. Furthermore, there is still a need for active ingredients to significantly protect against blue light‐induced hyperpigmentation in vivo.Our study had two aims: to detect visible changes in skin pigmentation following repeated irradiation of the skin with LED‐based blue light and to reduce pigmentation using suitable active ingredients.MethodWe conducted a randomized, double‐blind and placebo‐controlled clinical study on 33 female volunteers with skin phototypes III and IV. We used a repetitive blue light (4 × 60 J cm−2, 450 nm) irradiation protocol on the volunteers’ inner forearms. Using hyperspectral imaging, we assessed chromophore status. In addition, we took chromameter measurements and photographs to assess visible hyperpigmentation.ResultsWe measured significant changes in chromophore status (P < 0.001 vs baseline), that is of melanin, haemoglobin and oxygen saturation, immediately after blue light irradiation. In addition, we found visible skin colour changes which were expressed by a significant decrease in ITA° values (delta ITA° = −16.89, P < 0.001 vs baseline for the placebo group) and an increase in a* (delta a* = +3.37, P < 0.001 vs baseline for the placebo group) 24 h post‐irradiation. Hyperpigmentation and skin reddening were mitigated by both a formulation containing 3% of a microalgal product and a formulation containing 3% niacinamide.ConclusionOur study sets out an efficient and robust protocol for investigating both blue light‐induced cutaneous alterations, such as changes in skin chromophores, and signs of photoageing, such as hyperpigmentation. Moreover, we have shown evidence that both an extract of the microalga Scenedesmus rubescens and niacinamide (vitamin B3) have the potential to protect against blue light‐induced hyperpigmentation. |
| Author | Campiche, R. Laurent, G. Curpen, S. J. Schuetz, R. Lutchmanen‐Kolanthan, V. Gempeler, M. Cherel, M. Gougeon, S. |
| AuthorAffiliation | 2 Centre International de Développement Pharmaceutique (CIDP) BioPark Mauritius SOCOTA Phoenicia Sayed Hossen Road Phoenix 73408 Mauritius 1 DSM Nutritional Products Personal Care & Aroma Wurmisweg 576 Kaiseraugst 4303 Switzerland 3 Newtone Technologies 13 bis Place Jules Ferry Lyon 69006 France |
| AuthorAffiliation_xml | – name: 2 Centre International de Développement Pharmaceutique (CIDP) BioPark Mauritius SOCOTA Phoenicia Sayed Hossen Road Phoenix 73408 Mauritius – name: 1 DSM Nutritional Products Personal Care & Aroma Wurmisweg 576 Kaiseraugst 4303 Switzerland – name: 3 Newtone Technologies 13 bis Place Jules Ferry Lyon 69006 France |
| Author_xml | – sequence: 1 givenname: R. orcidid: 0000-0002-2216-7851 surname: Campiche fullname: Campiche, R. email: remo.campiche@dsm.com organization: Personal Care & Aroma – sequence: 2 givenname: S. J. surname: Curpen fullname: Curpen, S. J. organization: SOCOTA Phoenicia – sequence: 3 givenname: V. surname: Lutchmanen‐Kolanthan fullname: Lutchmanen‐Kolanthan, V. organization: SOCOTA Phoenicia – sequence: 4 givenname: S. surname: Gougeon fullname: Gougeon, S. organization: Newtone Technologies – sequence: 5 givenname: M. surname: Cherel fullname: Cherel, M. organization: Newtone Technologies – sequence: 6 givenname: G. surname: Laurent fullname: Laurent, G. organization: Personal Care & Aroma – sequence: 7 givenname: M. surname: Gempeler fullname: Gempeler, M. organization: Personal Care & Aroma – sequence: 8 givenname: R. orcidid: 0000-0003-2410-6128 surname: Schuetz fullname: Schuetz, R. organization: Personal Care & Aroma |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32478879$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kV1LHDEUhkNR6mp70T9QAt7Ui9FMks3M3Aiy-AWCQj9uQyZzshs7k2yTTBf_vdFRsUINB3JxnvNy3vPuoi3nHSD0pSSHZX5HVsfDkgpWfUCzkou6oLzhW2hGSk6LORdsB-3GeEsI4U3NPqIdRnlV11UzQ79u7HIAl1Sy3mEwBnSK2Bvc9iPg3i5XCdsQVGcnIlf8bR1WrsMrv8HJ43XwKU9htVTWxYTTCoZPaNuoPsLnp38P_Tw7_bG4KK6uzy8XJ1eFnpOmKqhWIExXglYVq6iC2ihiWmYIaVugjJNKE8WEaeaC87pTghPTNYYbQg0zHdtDx5PuemwH6HR2ElQv18EOKtxJr6z8t-PsSi79X1nxRhBRZ4FvTwLB_xkhJjnYqKHvlQM_Rkk5qeec5cro_hv01o_BZXuZyhdv8nnLTH19vdHLKs8nz8DBBOjgYwxgXpCSyIc4ZY5TPsaZ2aM3rLZTVNmM7d-b2Nge7v4vLS8X36eJexwTsic |
| CitedBy_id | crossref_primary_10_3390_ijms241310502 crossref_primary_10_1007_s13346_024_01593_y crossref_primary_10_1111_jocd_13837 crossref_primary_10_1007_s43630_021_00043_9 crossref_primary_10_3390_md19100552 crossref_primary_10_3390_pr11030917 crossref_primary_10_1016_j_jphotobiol_2021_112372 crossref_primary_10_1016_j_btre_2025_e00911 crossref_primary_10_1096_fj_202500746R crossref_primary_10_3390_nu14061217 crossref_primary_10_1111_dth_14790 crossref_primary_10_1111_jdv_18196 crossref_primary_10_1111_php_13863 crossref_primary_10_1016_j_progpolymsci_2023_101740 crossref_primary_10_3390_ijms26125554 crossref_primary_10_1016_j_pdpdt_2024_104325 crossref_primary_10_1111_ics_12794 crossref_primary_10_1111_jocd_14839 crossref_primary_10_4103_2045_9912_320704 crossref_primary_10_1093_asjof_ojae088 crossref_primary_10_1371_journal_pone_0281062 crossref_primary_10_3390_md20060342 crossref_primary_10_2478_acs_2024_0007 crossref_primary_10_1016_j_jaad_2021_12_023 crossref_primary_10_1016_j_matlet_2022_132529 crossref_primary_10_1111_jocd_15576 crossref_primary_10_1093_ced_llad150 crossref_primary_10_3390_cosmetics12040144 crossref_primary_10_3390_cosmetics11030080 crossref_primary_10_1007_s43630_024_00546_1 crossref_primary_10_1111_jocd_16292 crossref_primary_10_1016_j_biopha_2025_118442 crossref_primary_10_3390_cosmetics12050213 crossref_primary_10_1038_s41467_025_60911_1 crossref_primary_10_3389_fnut_2021_737059 crossref_primary_10_1111_srt_13401 crossref_primary_10_1111_jocd_13854 crossref_primary_10_1002_jvc2_586 crossref_primary_10_1016_j_arabjc_2023_105466 crossref_primary_10_1111_jocd_14232 crossref_primary_10_7759_cureus_42794 crossref_primary_10_1111_phpp_12736 crossref_primary_10_3390_jcm12237488 crossref_primary_10_3390_nu17010093 crossref_primary_10_3390_antiox11081449 crossref_primary_10_1002_jbio_202200257 crossref_primary_10_3390_molecules28052172 crossref_primary_10_1111_jocd_13803 crossref_primary_10_1111_jdv_19290 crossref_primary_10_1002_jbio_202400071 crossref_primary_10_1111_php_13454 crossref_primary_10_3390_ijms22052437 crossref_primary_10_1007_s40257_025_00933_z |
| Cites_doi | 10.1111/exd.13203 10.1038/jid.2011.476 10.1371/journal.pone.0130949 10.1111/phpp.12523 10.1111/ics.12450 10.1111/srt.12396 10.1002/jbm.b.30126 10.1038/jid.2012.148 10.1111/pcmr.12273 10.5114/ada.2017.67070 10.1046/j.1365-2133.2002.04834.x 10.1155/2016/7432797 10.1038/srep33847 10.1038/jid.2009.194 10.1111/j.1468-2494.2012.00718.x 10.1001/jama.1969.03160390039008 10.1046/j.1523-1747.2002.01708.x 10.1016/0009-2797(95)03653-9 10.1046/j.1467-2494.2002.00137.x 10.1111/j.1467-2494.2004.00228.x 10.1155/2015/579675 10.1038/jid.2010.95 10.3389/fmed.2018.00162 10.1111/j.1751-1097.2007.00286.x 10.1016/j.ecoenv.2017.02.055 10.1111/j.1600-0749.2006.00338.x 10.1111/j.1751-1097.1984.tb03905.x 10.1111/j.1600-0781.1996.tb00197.x 10.1111/phpp.12325 10.1073/pnas.96.11.6255 10.1111/j.1365-2133.1990.tb16121.x 10.1111/jocd.12025 10.1179/135100099101534882 10.1001/archderm.135.2.209-a 10.1111/exd.12987 |
| ContentType | Journal Article |
| Copyright | 2020 The Authors. published by John Wiley & Sons Ltd on behalf of Society of Cosmetic Scientists and Société Française de Cosmétologie 2020 The Authors. International Journal of Cosmetic Science published by John Wiley & Sons Ltd on behalf of Society of Cosmetic Scientists and Société Française de Cosmétologie. 2020. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: 2020 The Authors. published by John Wiley & Sons Ltd on behalf of Society of Cosmetic Scientists and Société Française de Cosmétologie – notice: 2020 The Authors. International Journal of Cosmetic Science published by John Wiley & Sons Ltd on behalf of Society of Cosmetic Scientists and Société Française de Cosmétologie. – notice: 2020. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | 24P AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QR 7U7 8FD C1K FR3 K9. P64 7X8 5PM |
| DOI | 10.1111/ics.12637 |
| DatabaseName | Wiley Online Library Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Chemoreception Abstracts Toxicology Abstracts Technology Research Database Environmental Sciences and Pollution Management Engineering Research Database ProQuest Health & Medical Complete (Alumni) Biotechnology and BioEngineering Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Technology Research Database Toxicology Abstracts ProQuest Health & Medical Complete (Alumni) Chemoreception Abstracts Engineering Research Database Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic Technology Research Database |
| Database_xml | – sequence: 1 dbid: 24P name: Wiley Online Library Open Access url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Economics Engineering |
| DocumentTitleAlternate | Blue light on skin |
| EISSN | 1468-2494 |
| EndPage | 406 |
| ExternalDocumentID | PMC7496068 32478879 10_1111_ics_12637 ICS12637 |
| Genre | article Randomized Controlled Trial Journal Article |
| GroupedDBID | --- .3N .GA .Y3 05W 0R~ 10A 1OB 1OC 24P 29J 31~ 33P 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5HH 5LA 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAESR AAEVG AAHHS AAHQN AAIPD AAMNL AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABDBF ABEML ABJNI ABPVW ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACGFO ACGFS ACGOF ACIWK ACMXC ACPOU ACPRK ACRPL ACSCC ACUHS ACXBN ACXQS ACYXJ ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZMN ADZOD AEEZP AEGXH AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFEBI AFFPM AFGKR AFPWT AFRAH AFWVQ AFZJQ AHBTC AHEFC AIACR AIAGR AITYG AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BGNMA BHBCM BMXJE BROTX BRXPI BY8 C45 CAG COF CS3 CYRXZ D-6 D-7 D-E D-F DC6 DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DU5 EAD EAP EBC EBD EBS EJD EMK EMOBN ESX EX3 F00 F01 F04 F5P FEDTE FUBAC FZ0 G-S G.N GODZA H.X HF~ HGLYW HVGLF HZI HZ~ IHE IX1 J0M K48 KBYEO LAK LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M4Y MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ NU0 O66 O9- OIG OVD P2P P2W P2X P2Z P4B P4D PALCI PQQKQ Q.N Q11 QB0 R.K RIWAO RJQFR ROL RX1 SAMSI SUPJJ SV3 TEORI TUS UB1 V8K W8V W99 WBKPD WHWMO WIH WIJ WIK WOHZO WOW WQJ WRC WUP WVDHM WXI WXSBR XG1 YFH YUY ZZTAW ~IA ~WT AAMMB AAYXX AEFGJ AEYWJ AGHNM AGQPQ AGXDD AGYGG AIDQK AIDYY AIQQE CITATION O8X CGR CUY CVF ECM EIF NPM 7QR 7U7 8FD C1K FR3 K9. P64 7X8 5PM |
| ID | FETCH-LOGICAL-c5097-2cae6fd1eca7372ae8fa0fb3f00bbe23407c0a36f956448da640fd9f4f02f3fd3 |
| IEDL.DBID | 24P |
| ISICitedReferencesCount | 57 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000550050000010&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0142-5463 1468-2494 |
| IngestDate | Tue Nov 04 01:59:21 EST 2025 Fri Jul 11 09:48:06 EDT 2025 Sat Nov 29 14:50:46 EST 2025 Mon Jul 21 05:14:50 EDT 2025 Sat Nov 29 02:45:47 EST 2025 Tue Nov 18 22:39:06 EST 2025 Wed Jan 22 16:34:43 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Keywords | niacinamide skin hyperpigmentation Blue light Scenedesmus rubescens |
| Language | English |
| License | Attribution 2020 The Authors. International Journal of Cosmetic Science published by John Wiley & Sons Ltd on behalf of Society of Cosmetic Scientists and Société Française de Cosmétologie. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c5097-2cae6fd1eca7372ae8fa0fb3f00bbe23407c0a36f956448da640fd9f4f02f3fd3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Undefined-3 |
| ORCID | 0000-0003-2410-6128 0000-0002-2216-7851 |
| OpenAccessLink | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fics.12637 |
| PMID | 32478879 |
| PQID | 2424990041 |
| PQPubID | 1086359 |
| PageCount | 8 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7496068 proquest_miscellaneous_2408543543 proquest_journals_2424990041 pubmed_primary_32478879 crossref_primary_10_1111_ics_12637 crossref_citationtrail_10_1111_ics_12637 wiley_primary_10_1111_ics_12637_ICS12637 |
| PublicationCentury | 2000 |
| PublicationDate | August 2020 |
| PublicationDateYYYYMMDD | 2020-08-01 |
| PublicationDate_xml | – month: 08 year: 2020 text: August 2020 |
| PublicationDecade | 2020 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England – name: Oxford – name: Hoboken |
| PublicationTitle | International journal of cosmetic science |
| PublicationTitleAlternate | Int J Cosmet Sci |
| PublicationYear | 2020 |
| Publisher | Wiley Subscription Services, Inc John Wiley and Sons Inc |
| Publisher_xml | – name: Wiley Subscription Services, Inc – name: John Wiley and Sons Inc |
| References | 2017; 26 2004; 26 2015; 10 2014; 27 2002; 118 2020; 36 2006; 19 2016; 2016 1999; 4 2018; 40 2012; 34 1990; 122 1996; 12 2018; 24 1996; 99 2016; 6 2018; 133 2012; 132 2018; 5 1984; 39 2013; 12 1986; 3 2017; 33 2002; 24 2002; 147 2017; 34 2015; 2015 2010; 130 1999; 135 2017; 140 1999; 96 2005; 72 2008; 84 2016; 25 1969; 210 e_1_2_8_28_1 e_1_2_8_29_1 e_1_2_8_24_1 e_1_2_8_25_1 e_1_2_8_26_1 e_1_2_8_27_1 e_1_2_8_2_1 e_1_2_8_5_1 e_1_2_8_4_1 e_1_2_8_7_1 e_1_2_8_6_1 e_1_2_8_9_1 e_1_2_8_8_1 e_1_2_8_20_1 e_1_2_8_21_1 e_1_2_8_22_1 e_1_2_8_23_1 e_1_2_8_17_1 e_1_2_8_18_1 e_1_2_8_19_1 e_1_2_8_13_1 e_1_2_8_36_1 e_1_2_8_35_1 e_1_2_8_15_1 e_1_2_8_38_1 e_1_2_8_16_1 e_1_2_8_37_1 Kligman L.H. (e_1_2_8_3_1) 1986; 3 e_1_2_8_32_1 e_1_2_8_10_1 e_1_2_8_31_1 e_1_2_8_11_1 Mendrok‐Edinger C. (e_1_2_8_14_1) 2018; 133 e_1_2_8_34_1 e_1_2_8_12_1 e_1_2_8_33_1 e_1_2_8_30_1 |
| References_xml | – volume: 3 start-page: 215 year: 1986 end-page: 227 article-title: The nature of photoaging: its prevention and repair publication-title: Photodermatology – volume: 130 start-page: 259 year: 2010 end-page: 269 article-title: Blue‐light irradiation regulates proliferation and differentiation in human skin cells publication-title: J. Invest. Dermatol. – volume: 36 start-page: 135 year: 2020 end-page: 144 article-title: High‐energy visible light at ambient doses and intensities induces oxidative stress of skin—Protective effects of the antioxidant and Nrf2 inducer Licochalcone A in vitro and in vivo publication-title: Photodermatol., Photoimmunol. Photomed. – volume: 2015 start-page: 579675 year: 2015 article-title: Blue‐violet light irradiation dose dependently decreases carotenoids in human skin, which indicates the generation of free radicals publication-title: Oxid. Med. Cell Longev. – volume: 10 year: 2015 article-title: Visible light induces melanogenesis in human skin through a photoadaptive response publication-title: PLoS One – volume: 25 start-page: 380 year: 2016 end-page: 385 article-title: Free radicals induced by sunlight in different spectral regions ‐ in vivo versus ex vivo study publication-title: Exp. Dermatol. – volume: 99 start-page: 1 year: 1996 end-page: 16 article-title: Methylene blue plus light‐induced lipid peroxidation in rat liver microsomes: inhibition by nicotinamide (vitamin B3) and other antioxidants publication-title: Chemico‐Biol. Interact. – volume: 24 start-page: 170 year: 2002 end-page: 185 article-title: In vivo and in vitro assessment of UVA protection by sunscreen formulations containing either butyl methoxy dibenzoyl methane, methylene bis‐benzotriazolyl tetramethylbutylphenol, or microfine ZnO publication-title: Int. J. Cosmet. Sci. – volume: 5 start-page: 162 year: 2018 article-title: Novel means for photoprotection publication-title: Front. Med. (Lausanne) – volume: 72 start-page: 223 year: 2005 end-page: 229 article-title: Blue light differentially alters cellular redox properties publication-title: J. Biomed. Mater. Res. B Appl. Biomater. – volume: 33 start-page: 260 year: 2017 end-page: 266 article-title: A method to assess the protective efficacy of sunscreens against visible light‐induced pigmentation publication-title: Photodermatol. Photoimmunol. Photomed. – volume: 6 start-page: 33847 year: 2016 article-title: Gene expression profiling reveals aryl hydrocarbon receptor as a possible target for photobiomodulation when using blue light publication-title: Sci. Rep. – volume: 27 start-page: 822 year: 2014 end-page: 826 article-title: Differences in visible light‐induced pigmentation according to wavelengths: a clinical and histological study in comparison with UVB exposure publication-title: Pigment Cell Melanoma Res. – volume: 24 start-page: 99 year: 2018 end-page: 107 article-title: SpectraCam((R)): A new polarized hyperspectral imaging system for repeatable and reproducible in vivo skin quantification of melanin, total hemoglobin, and oxygen saturation publication-title: Skin Res. Technol. – volume: 40 start-page: 187 year: 2018 end-page: 192 article-title: Protective effects of an extract of the freshwater microalga Scenedesmus rubescens on UV‐irradiated skin cells publication-title: Int. J. Cosmet. Sci. – volume: 140 start-page: 256 year: 2017 end-page: 263 article-title: Zinc‐induced differential oxidative stress and antioxidant responses in Chlorella sorokiniana and Scenedesmus acuminatus publication-title: Ecotoxicol. Environ. Saf. – volume: 210 start-page: 2377 year: 1969 end-page: 2380 article-title: Early destructive effect of sunlight on human skin publication-title: JAMA – volume: 39 start-page: 651 year: 1984 end-page: 659 article-title: An experimental study of the changes in pigmentation in human skin in vivo with visible and near infrared light publication-title: Photochem. Photobiol. – volume: 122 start-page: 21 issue: Suppl 35 year: 1990 end-page: 28 article-title: Pigmentary changes of the ageing skin publication-title: Br. J. Dermatol. – volume: 4 start-page: 179 year: 1999 end-page: 184 article-title: Nicotinamide (vitamin B3) as an effective antioxidant against oxidative damage in rat brain mitochondria publication-title: Redox Rep. – volume: 132 start-page: 1901 year: 2012 end-page: 1907 article-title: Irradiation of skin with visible light induces reactive oxygen species and matrix‐degrading enzymes publication-title: J. Invest. Dermatol. – volume: 133 start-page: 12 year: 2018 end-page: 29 article-title: Into the blue publication-title: Cosmet. Toiletries. – volume: 26 start-page: 242 year: 2017 end-page: 248 article-title: Molecular and histological characterization of age spots publication-title: Exp. Dermatol. – volume: 132 start-page: 1756 year: 2012 end-page: 1757 article-title: How much sun protection is needed?: Are we on the way to full‐spectrum protection? publication-title: J. Invest. Dermatol. – volume: 135 start-page: 209 year: 1999 end-page: 210 article-title: The absorption properties of "physical" sunscreens publication-title: Arch. Dermatol. – volume: 12 start-page: 12 year: 2013 end-page: 17 article-title: Efficacy of hydroquinone‐free skin‐lightening cream for photoaging publication-title: J. Cosmet. Dermatol. – volume: 130 start-page: 2092 issue: 8 year: 2010 end-page: 2097 article-title: Impact of long‐wavelength UVA and visible light on melanocompetent skin publication-title: J. Invest. Dermatol. – volume: 84 start-page: 450 year: 2008 end-page: 462 article-title: Effects of visible light on the skin publication-title: Photochem. Photobiol. – volume: 2016 start-page: 1 year: 2016 end-page: 9 article-title: Oxidative stress and inflammation: what polyphenols can do for us? publication-title: Oxidative Med. Cellular Longevity. – volume: 19 start-page: 606 year: 2006 end-page: 614 article-title: Relationship between skin response to ultraviolet exposure and skin color type publication-title: Pigment Cell Res. – volume: 26 start-page: 231 year: 2004 end-page: 238 article-title: Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin publication-title: Int. J. Cosmet. Sci. – volume: 12 start-page: 183 year: 1996 end-page: 188 article-title: Erythema and melanogenesis action spectra in heavily pigmented individuals as compared to fair‐skinned Caucasians publication-title: Photodermatol. Photoimmunol. Photomed. – volume: 118 start-page: 618 year: 2002 end-page: 625 article-title: Photoaging is associated with protein oxidation in human skin in vivo publication-title: J. Invest. Dermatol. – volume: 34 start-page: 97 year: 2017 end-page: 103 article-title: Melanin and lipofuscin as hallmarks of skin aging publication-title: Postepy Dermatol. Alergol. – volume: 34 start-page: 285 year: 2012 end-page: 290 article-title: The Radical Status Factor (RSF): a novel metric to characterize skin products publication-title: Int. J. Cosmet. Sci. – volume: 96 start-page: 6255 year: 1999 end-page: 6260 article-title: Activation of flavin‐containing oxidases underlies light‐induced production of H2O2 in mammalian cells publication-title: Proc. Natl. Acad. Sci. – volume: 147 start-page: 20 year: 2002 end-page: 31 article-title: The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer publication-title: Br. J. Dermatol. – ident: e_1_2_8_19_1 doi: 10.1111/exd.13203 – ident: e_1_2_8_9_1 doi: 10.1038/jid.2011.476 – ident: e_1_2_8_21_1 doi: 10.1371/journal.pone.0130949 – ident: e_1_2_8_11_1 doi: 10.1111/phpp.12523 – ident: e_1_2_8_27_1 doi: 10.1111/ics.12450 – ident: e_1_2_8_28_1 doi: 10.1111/srt.12396 – ident: e_1_2_8_8_1 doi: 10.1002/jbm.b.30126 – ident: e_1_2_8_24_1 doi: 10.1038/jid.2012.148 – ident: e_1_2_8_16_1 doi: 10.1111/pcmr.12273 – volume: 133 start-page: 12 year: 2018 ident: e_1_2_8_14_1 article-title: Into the blue publication-title: Cosmet. Toiletries. – ident: e_1_2_8_32_1 doi: 10.5114/ada.2017.67070 – ident: e_1_2_8_38_1 doi: 10.1046/j.1365-2133.2002.04834.x – ident: e_1_2_8_33_1 doi: 10.1155/2016/7432797 – ident: e_1_2_8_6_1 doi: 10.1038/srep33847 – ident: e_1_2_8_10_1 doi: 10.1038/jid.2009.194 – ident: e_1_2_8_23_1 doi: 10.1111/j.1468-2494.2012.00718.x – ident: e_1_2_8_2_1 doi: 10.1001/jama.1969.03160390039008 – ident: e_1_2_8_13_1 doi: 10.1046/j.1523-1747.2002.01708.x – ident: e_1_2_8_35_1 doi: 10.1016/0009-2797(95)03653-9 – ident: e_1_2_8_26_1 doi: 10.1046/j.1467-2494.2002.00137.x – ident: e_1_2_8_37_1 doi: 10.1111/j.1467-2494.2004.00228.x – ident: e_1_2_8_12_1 doi: 10.1155/2015/579675 – ident: e_1_2_8_20_1 doi: 10.1038/jid.2010.95 – ident: e_1_2_8_5_1 doi: 10.3389/fmed.2018.00162 – ident: e_1_2_8_4_1 doi: 10.1111/j.1751-1097.2007.00286.x – ident: e_1_2_8_34_1 doi: 10.1016/j.ecoenv.2017.02.055 – ident: e_1_2_8_29_1 doi: 10.1111/j.1600-0749.2006.00338.x – ident: e_1_2_8_15_1 doi: 10.1111/j.1751-1097.1984.tb03905.x – ident: e_1_2_8_31_1 doi: 10.1111/j.1600-0781.1996.tb00197.x – ident: e_1_2_8_30_1 doi: 10.1111/phpp.12325 – ident: e_1_2_8_7_1 doi: 10.1073/pnas.96.11.6255 – ident: e_1_2_8_17_1 doi: 10.1111/j.1365-2133.1990.tb16121.x – ident: e_1_2_8_18_1 doi: 10.1111/jocd.12025 – ident: e_1_2_8_36_1 doi: 10.1179/135100099101534882 – ident: e_1_2_8_25_1 doi: 10.1001/archderm.135.2.209-a – volume: 3 start-page: 215 year: 1986 ident: e_1_2_8_3_1 article-title: The nature of photoaging: its prevention and repair publication-title: Photodermatology – ident: e_1_2_8_22_1 doi: 10.1111/exd.12987 |
| SSID | ssj0004983 |
| Score | 2.4746308 |
| Snippet | Background
Visible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies... Visible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies demonstrating the... BackgroundVisible light, in particular blue light, has been identified as an additional contributor to cutaneous photoageing. However, clinical studies... We provide here a method to study blue light induced changes in skin in vivo. We show that an algal extract and niacinamide can mitigate blue light induced... |
| SourceID | pubmedcentral proquest pubmed crossref wiley |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 399 |
| SubjectTerms | Administration, Cutaneous Adult Algae Blue light Change detection Chromophores Double-Blind Method Female Hemoglobin Humans Hyperpigmentation Hyperspectral imaging In vivo methods and tests Ingredients Irradiation Light Light emitting diodes Light irradiation Melanin Microalgae niacinamide Niacinamide - administration & dosage Nicotinamide Nicotinic acid Original Oxygen content Pigmentation Placebos Scenedesmus rubescens Skin Skin Aging - radiation effects Skin pigmentation Skin Pigmentation - radiation effects Young Adult |
| Title | Pigmentation effects of blue light irradiation on skin and how to protect against them |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fics.12637 https://www.ncbi.nlm.nih.gov/pubmed/32478879 https://www.proquest.com/docview/2424990041 https://www.proquest.com/docview/2408543543 https://pubmed.ncbi.nlm.nih.gov/PMC7496068 |
| Volume | 42 |
| WOSCitedRecordID | wos000550050000010&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVWIB databaseName: Wiley Online Library - Journals customDbUrl: eissn: 1468-2494 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0004983 issn: 0142-5463 databaseCode: DRFUL dateStart: 19970101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3di9QwEB_OO_HjwY_1q3oeUXzwpZI02abFJzldFPRY1JN9K2mT3BXXVra7-u87SdO6yykIQimFTGmazCS_SWZ-AXimvetj8ricOlJtrlicV9M0VkILnWlbckX9YRPy5CRbLPL5HrwccmF6fohxwc1Zhh-vnYGrstsy8rrqXrAk5fISHDDGpVPpRMx_J0XmPQcnE47sP-WBVsiF8Yyv7k5GFxDmxUDJbQDrZ6DZzf-q-y24EYAnedVrym3YM80Erg55yd0Erm9RE07gyoew6X4Hvszrs28hRakhIQCEtJaUy40hS-fdk3q1ciQHXgKv7mvdENVoct7-JOuWBDYIos5UjXiUOKrYu3A6e_P5-G0cjmOIK0QVMk4qZVKrmamUO9tGmcwqip1pKS1Lk3B0DSuqeGrR5UKnT6tUUKtzKyxNLLea34P9pm3MAyASBxoqc4QXthTcMkUNji5KTWnF8HURwfOhX4oqcJW7IzOWxeCzYMMUvgUjeDqKfu8JOv4kdDh0bhFstCtcYgzOxVSwCJ6MxWhdbstENabdOBmEpIgoBY_gfq8L41cQirpQzDwCuaMlo4Bj7t4taepzz-AthXMcM_xNryV_r3jx7viTf3j476KP4FriFgV8lOIh7K9XG_MYLlc_1nW3OvJGgne5yI7g4PXH2en7XzjpF5Y |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3db9MwED-NDjF44KMwCAwwiIe9BDmxmzQSL2hQbaKrJtjQ3iLHH1tEl6CmhX-fs-OEVgMJCSkPkXxWHPvO_p199zPAG-VcH52FxciSajMRhZkcJaHgiquxMgUT1F02kc5m4_Pz7GQL3nW5MC0_RL_hZi3DzdfWwO2G9JqVl7J5G8UJS2_ANkc1Gg1g-8Pnydn0d15k1tJwRtzy_SfMMwvZSJ6-8uZ6dA1kXo-VXMewbhGa3Pu_5t-Hux58kvettjyALV0NYafLTW6GcGeNnnAIt479wftD-HpSXlz5NKWK-CAQUhtSzFeazK2HT8rFwhIdOAl8mm9lRUSlyGX9kyxr4hkhiLgQJWJSYuliH8HZ5OPpwWHor2QIJSKLNIyl0IlRkZbC3m8j9NgIigNqKC0KHTN0DyUVLDHodqHjp0TCqVGZ4YbGhhnFdmFQ1ZV-AiTFyYamGUIMU3BmIkE1zjBCjKiMsDoPYL8bmFx6vnJ7bcY87_wW7Jjc9WAAr3vR7y1Jx5-E9rrRzb2dNrlNjsH1mPIogFd9MVqYPTYRla5XVgZhKaJKzgJ43CpD_xWEozYcMwsg3VCTXsCyd2-WVOWlY_FOuXUex_ibTk3-3vD86OCLe3n676IvYefw9HiaT49mn57B7dhuErioxT0YLBcr_Rxuyh_Lslm88DbzC3zvGos |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB6VggoceCyvQAGDOPQS5MTeZCNxQYUVFbBaiYd6i5zYbqNuk2qzC3-fGccJuypISEg5RPJYcewZ-xt75jPAK-1cH5OFxZhItYWKwqwcJ6GSWuqJtoVQ3F02kc5mk-PjbL4Db_pcmI4fYthwI8tw8zUZuLnQdsPKq7J9HcWJSK_AVTnGOZZ4neX8d1Zk1pFwRpLY_hPheYUojmeour0aXYKYlyMlNxGsW4Kmt_-v8Xfgloee7G2nK3dhx9QjuN5nJrcjuLlBTjiCvc_-2P0efJ9XJ-c-SalmPgSENZYVi7VhC_LvWbVcEs2Bk8CnPatqpmrNTpufbNUwzwfB1ImqEJEyIou9D9-m778efgj9hQxhibgiDeNSmcTqyJSKbrdRZmIVx-G0nBeFiQU6hyVXIrHodKHbp1UiudWZlZbHVlgtHsBu3dTmEbAUpxqeZggwbCGFjRQ3OL8oNeZlhNVlAAf9wOSlZyunSzMWee-1YMfkrgcDeDmIXnQUHX8S2u9HN_dW2uaUGoOrMZdRAC-GYrQvOjRRtWnWJIOgFDGlFAE87JRh-AqCUQrGzAJIt9RkECDu7u2Sujp1HN6pJNdxgr_p1OTvDc-PDr-4l8f_Lvoc9ubvpvmno9nHJ3Ajph0CF7K4D7ur5do8hWvlj1XVLp85g_kF5nUYdA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pigmentation+effects+of+blue+light+irradiation+on+skin+and+how+to+protect+against+them&rft.jtitle=International+journal+of+cosmetic+science&rft.au=Campiche%2C+R.&rft.au=Curpen%2C+S.+J.&rft.au=Lutchmanen%E2%80%90Kolanthan%2C+V.&rft.au=Gougeon%2C+S.&rft.date=2020-08-01&rft.pub=John+Wiley+and+Sons+Inc&rft.issn=0142-5463&rft.eissn=1468-2494&rft.volume=42&rft.issue=4&rft.spage=399&rft.epage=406&rft_id=info:doi/10.1111%2Fics.12637&rft_id=info%3Apmid%2F32478879&rft.externalDocID=PMC7496068 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0142-5463&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0142-5463&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0142-5463&client=summon |