A mixed‐methods study of cyclin‐dependent kinase 4 and 6 inhibitor symptom burden and quality of life among metastatic breast cancer patients and providers

Background Cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor targeted therapies dramatically improve survival outcomes for metastatic breast cancer (MBC), but they are associated with significant symptom burden that can impact patients’ health‐related quality of life (HRQOL) and treatment outcomes....

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Bibliographic Details
Published in:	Cancer medicine (Malden, MA) Vol. 10; no. 14; pp. 4823 - 4831
Main Authors:	Oswald, Laura B., Arredondo, Brandy, Kadono, Mika, Martinez‐Tyson, Dinorah, Meade, Cathy D., Penedo, Frank, Antoni, Michael H., Soliman, Hatem, Costa, Ricardo L. B., Jim, Heather S. L.
Format:	Journal Article
Language:	English
Published:	United States John Wiley & Sons, Inc 01.07.2021 John Wiley and Sons Inc Wiley
Subjects:	Adult Advanced practice nurses Aged Breast cancer breast neoplasms Breast Neoplasms - chemistry Breast Neoplasms - drug therapy Breast Neoplasms - pathology Breast Neoplasms - psychology Cancer therapies Clinical Cancer Research Clinical trials Cyclin-dependent kinase 4 Cyclin-Dependent Kinase 4 - antagonists & inhibitors Cyclin-Dependent Kinase 6 - antagonists & inhibitors Cyclin-Dependent Kinase Inhibitor Proteins - adverse effects Cyclin-Dependent Kinase Inhibitor Proteins - therapeutic use Cyclin-dependent kinases Demographics Endocrine therapy Enzyme inhibitors Ethnicity Fatigue - chemically induced Female Hispanic Americans Humans Medical prognosis Metastases Metastasis Middle Aged Mixed methods research Molecular Targeted Therapy Needs Assessment neoplasm metastasis Oncologists Oncology Original Research Patient Reported Outcome Measures Patients patient‐reported outcomes measures psycho‐oncology Qualitative Research Quality of Life Symptom management patient-reported outcomes measures neoplasm metastasis qualitative research quality of life breast neoplasms psycho-oncology
ISSN:	2045-7634, 2045-7634
Online Access:	Get full text
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