Hypertension in older adults: Assessment, management, and challenges
Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the wo...
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| Veröffentlicht in: | Clinical cardiology (Mahwah, N.J.) Jg. 43; H. 2; S. 99 - 107 |
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| Hauptverfasser: | , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
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New York
Wiley Periodicals, Inc
01.02.2020
John Wiley & Sons, Inc |
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| ISSN: | 0160-9289, 1932-8737, 1932-8737 |
| Online-Zugang: | Volltext |
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| Abstract | Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho‐social factors, and must therefore be individualized. Non‐pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin‐angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age. |
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| AbstractList | Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho‐social factors, and must therefore be individualized. Non‐pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin‐angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age. Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho-social factors, and must therefore be individualized. Non-pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin-angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age.Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho-social factors, and must therefore be individualized. Non-pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin-angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age. |
| Author | Goldberg, Alan Williams, Kim A. Fugar, Setri Madan, Nidhi Kyung, Stella Oliveros, Estefania Patel, Hena |
| AuthorAffiliation | 1 Department of Internal Medicine, Division of Cardiology Rush University Medical Center |
| AuthorAffiliation_xml | – name: 1 Department of Internal Medicine, Division of Cardiology Rush University Medical Center |
| Author_xml | – sequence: 1 givenname: Estefania orcidid: 0000-0003-1780-1982 surname: Oliveros fullname: Oliveros, Estefania email: estefaniaoliveros@gmail.com organization: Rush University Medical Center – sequence: 2 givenname: Hena surname: Patel fullname: Patel, Hena organization: Rush University Medical Center – sequence: 3 givenname: Stella surname: Kyung fullname: Kyung, Stella organization: Rush University Medical Center – sequence: 4 givenname: Setri surname: Fugar fullname: Fugar, Setri organization: Rush University Medical Center – sequence: 5 givenname: Alan surname: Goldberg fullname: Goldberg, Alan organization: Rush University Medical Center – sequence: 6 givenname: Nidhi surname: Madan fullname: Madan, Nidhi organization: Rush University Medical Center – sequence: 7 givenname: Kim A. surname: Williams fullname: Williams, Kim A. organization: Rush University Medical Center |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31825114$$D View this record in MEDLINE/PubMed |
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| Copyright | 2019 The Authors. published by Wiley Periodicals, Inc. 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
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