Hypertension in older adults: Assessment, management, and challenges

Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the wo...

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Veröffentlicht in:Clinical cardiology (Mahwah, N.J.) Jg. 43; H. 2; S. 99 - 107
Hauptverfasser: Oliveros, Estefania, Patel, Hena, Kyung, Stella, Fugar, Setri, Goldberg, Alan, Madan, Nidhi, Williams, Kim A.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: New York Wiley Periodicals, Inc 01.02.2020
John Wiley & Sons, Inc
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ISSN:0160-9289, 1932-8737, 1932-8737
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Abstract Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho‐social factors, and must therefore be individualized. Non‐pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin‐angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age.
AbstractList Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho‐social factors, and must therefore be individualized. Non‐pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin‐angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age.
Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho-social factors, and must therefore be individualized. Non-pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin-angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age.Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden of hypertension is increasing due to an aging population and increasing prevalence of obesity, and is estimated to affect one third of the world's population by 2025. Adverse outcomes in older adults are compounded by mechanical hemodynamic changes, arterial stiffness, neurohormonal and autonomic dysregulation, and declining renal function. This review highlights the current evidence and summarizes recent guidelines on hypertension, pertaining to older adults. Management strategies for hypertension in older adults must consider the degree of frailty, increasingly complex medical comorbidities, and psycho-social factors, and must therefore be individualized. Non-pharmacological lifestyle interventions should be encouraged to mitigate the risk of developing hypertension, and as an adjunctive therapy to reduce the need for medications. Pharmacological therapy with diuretics, renin-angiotensin system blockers, and calcium channel blockers have all shown benefit on cardiovascular outcomes in older patients. Given the economic and public health burden of hypertension in the United States and globally, it is critical to address lifestyle modifications in younger generations to prevent hypertension with age.
Author Goldberg, Alan
Williams, Kim A.
Fugar, Setri
Madan, Nidhi
Kyung, Stella
Oliveros, Estefania
Patel, Hena
AuthorAffiliation 1 Department of Internal Medicine, Division of Cardiology Rush University Medical Center
AuthorAffiliation_xml – name: 1 Department of Internal Medicine, Division of Cardiology Rush University Medical Center
Author_xml – sequence: 1
  givenname: Estefania
  orcidid: 0000-0003-1780-1982
  surname: Oliveros
  fullname: Oliveros, Estefania
  email: estefaniaoliveros@gmail.com
  organization: Rush University Medical Center
– sequence: 2
  givenname: Hena
  surname: Patel
  fullname: Patel, Hena
  organization: Rush University Medical Center
– sequence: 3
  givenname: Stella
  surname: Kyung
  fullname: Kyung, Stella
  organization: Rush University Medical Center
– sequence: 4
  givenname: Setri
  surname: Fugar
  fullname: Fugar, Setri
  organization: Rush University Medical Center
– sequence: 5
  givenname: Alan
  surname: Goldberg
  fullname: Goldberg, Alan
  organization: Rush University Medical Center
– sequence: 6
  givenname: Nidhi
  surname: Madan
  fullname: Madan, Nidhi
  organization: Rush University Medical Center
– sequence: 7
  givenname: Kim A.
  surname: Williams
  fullname: Williams, Kim A.
  organization: Rush University Medical Center
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31825114$$D View this record in MEDLINE/PubMed
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ContentType Journal Article
Copyright 2019 The Authors. published by Wiley Periodicals, Inc.
2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc.
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– notice: 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc.
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Keywords older adult
geriatrics
antihypertensive agents
hypertension
blood pressure monitoring
Language English
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2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc.
This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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Snippet Hypertension in older adults is related to adverse cardiovascular outcomes, such as heart failure, stroke, myocardial infarction, and death. The global burden...
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SubjectTerms Age
Age Factors
Aged
Aged, 80 and over
Aging
Alzheimer's disease
antihypertensive agents
Antihypertensive Agents - therapeutic use
Blood pressure
Blood Pressure - drug effects
blood pressure monitoring
Cardiology
Cardiovascular disease
Coronary vessels
Frailty
geriatrics
Health Status
Healthy Lifestyle
Heart rate
Humans
Hypertension
Hypertension - diagnosis
Hypertension - epidemiology
Hypertension - physiopathology
Hypertension - therapy
Meals
older adult
Older people
Patients
Physicians
Population
Practice Guidelines as Topic
Pressure measurement
Review
Reviews
Risk Factors
Risk Reduction Behavior
Treatment Outcome
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Title Hypertension in older adults: Assessment, management, and challenges
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Volume 43
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