Enterovirus infection and type 1 diabetes: unraveling the crime scene

Summary Enteroviruses (EV) have been historically associated to type 1 diabetes. Definitive proof for their implication in disease development is lacking, but growing evidence suggests that they could be involved in beta cell destruction either directly by killing beta cells or indirectly by creatin...

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Veröffentlicht in:	Clinical and experimental immunology Jg. 195; H. 1; S. 15 - 24
1. Verfasser:	Rodriguez‐Calvo, T.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 01.01.2019 John Wiley and Sons Inc
Schlagworte:	Animals Antigen presentation Antigens Apoptosis Autoimmunity beta cell destruction Beta cells Capsid protein Cell death Cell recognition Chemokines Crime scenes Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - immunology eIF-2 kinase Enterovirus - physiology Enterovirus Infections - immunology Enteroviruses Gene Expression Regulation Glucose Histocompatibility antigen HLA Humans Inflammation Insulin-Secreting Cells - physiology Insulitis Interferon interferon response Interferons - genetics Interferons - metabolism Islets of Langerhans Kinases Lymphocytes T Melanoma Myxovirus resistance proteins Pathogens in Autoimmune Disease Series Editor: Urs Christen Protein kinase R Proteins Retinoic acid Review Ribonucleic acid RNA T-Lymphocytes - immunology type 1 diabetes virus infection type 1 diabetes beta cell destruction interferon response virus infection
ISSN:	0009-9104, 1365-2249, 1365-2249
Online-Zugang:	Volltext
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