Volatile organic compounds in breath can serve as a non‐invasive diagnostic biomarker for the detection of advanced adenomas and colorectal cancer

Summary Background Colorectal cancer (CRC) is the third most common cancer diagnosis in the Western world. Aim To evaluate exhaled volatile organic compounds (VOCs) as a non‐invasive biomarker for the detection of CRC and precursor lesions using an electronic nose. Methods In this multicentre study...

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Bibliographic Details
Published in:	Alimentary pharmacology & therapeutics Vol. 51; no. 3; pp. 334 - 346
Main Authors:	Keulen, Kelly E., Jansen, Maud E., Schrauwen, Ruud W. M., Kolkman, Jeroen J., Siersema, Peter D.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.02.2020 John Wiley and Sons Inc
Subjects:	Adenoma Adenoma - diagnosis Adenoma - metabolism Adenoma - pathology Aged Biomarkers Biomarkers, Tumor - analysis Biomarkers, Tumor - metabolism Breath Analysis for Diagnosis of Colorectal Adenomas and Cancer Breath tests Breath Tests - instrumentation Breath Tests - methods Case-Control Studies Colitis Colonoscopy Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Cross-Sectional Studies Diagnosis Disease Progression Early Detection of Cancer - instrumentation Early Detection of Cancer - methods Electronic Nose - standards Electronic noses Exhalation - physiology Female Humans Inflammatory bowel diseases Intestine Lesions Male Malignancy Middle Aged Models, Biological Neoplasm Staging Netherlands Organic compounds Original Precancerous Conditions - diagnosis Precancerous Conditions - metabolism Precancerous Conditions - pathology Sensitivity and Specificity Tumors VOCs Volatile organic compounds Volatile Organic Compounds - analysis Volatile Organic Compounds - metabolism Netherlands
ISSN:	0269-2813, 1365-2036, 1365-2036
Online Access:	Get full text
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