Activation of brain‐derived neurotrophic factor signaling in the basal forebrain reverses acute sleep deprivation‐induced fear memory impairments

Introduction The mechanisms underlying sleep deprivation‐induced memory impairments and relevant compensatory signaling pathways remain elusive. We tested the hypothesis that increased brain‐derived neurotrophic factor (BDNF) expression in the basal forebrain following acute sleep deprivation was a...

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Vydané v:	Brain and behavior Ročník 10; číslo 4; s. e01592 - n/a
Hlavní autori:	Ma, Tao, Zhang, Hao, Xu, Zhi‐Peng, Lu, Yan, Fu, Qiang, Wang, Wei, Li, Guan‐Hua, Wang, Ying‐Ying, Yang, Yi‐Tian, Mi, Wei‐Dong
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States John Wiley & Sons, Inc 01.04.2020 John Wiley and Sons Inc Wiley
Predmet:	Animals Azepines - pharmacology Azepines - therapeutic use basal forebrain Basal Forebrain - drug effects Basal Forebrain - metabolism Benzamides - pharmacology Benzamides - therapeutic use Brain research Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - pharmacology Brain-Derived Neurotrophic Factor - therapeutic use Experiments Eye movements Fear - physiology fear memory Kinases Laboratory animals Male Medical research Memory Memory Disorders - drug therapy Memory Disorders - etiology Memory Disorders - metabolism Original Research Phosphorylation - drug effects Rats Rats, Wistar Receptor, trkB - antagonists & inhibitors Receptor, trkB - metabolism Signal Transduction - drug effects Signal Transduction - physiology Sleep - physiology Sleep deprivation Sleep Deprivation - complications Sleep Deprivation - metabolism Surgery Treatment Outcome China sleep deprivation brain-derived neurotrophic factor fear memory basal forebrain
ISSN:	2162-3279, 2162-3279
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