A Large‐scale, multicenter serum metabolite biomarker identification study for the early detection of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the third most lethal cancer worldwide. The lack of effective biomarkers for the early detection of HCC results in unsatisfactory curative treatments. Here, metabolite biomarkers were identified and validated for HCC diagnosis. A total of 1,448 subjects, including h...

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Bibliographic Details
Published in:	Hepatology (Baltimore, Md.) Vol. 67; no. 2; pp. 662 - 675
Main Authors:	Luo, Ping, Yin, Peiyuan, Hua, Rui, Tan, Yexiong, Li, Zaifang, Qiu, Gaokun, Yin, Zhenyu, Xie, Xingwang, Wang, Xiaomei, Chen, Wenbin, Zhou, Lina, Wang, Xiaolin, Li, Yanli, Chen, Hongsong, Gao, Ling, Lu, Xin, Wu, Tangchun, Wang, Hongyang, Niu, Junqi, Xu, Guowang
Format:	Journal Article
Language:	English
Published:	United States Wolters Kluwer Health, Inc 01.02.2018 John Wiley and Sons Inc
Subjects:	Adult Aged alpha-Fetoproteins - analysis Bile Acids and Salts - blood Biomarkers Biomarkers, Tumor - blood Carcinoma, Hepatocellular - blood Carcinoma, Hepatocellular - diagnosis Chronic infection Cirrhosis Diagnosis Early Detection of Cancer Female Hepatitis B Hepatocellular carcinoma Hepatology Humans Interferon Liquid chromatography Liver cancer Liver cirrhosis Liver Neoplasms - blood Liver Neoplasms - diagnosis Male Mass spectroscopy Metabolomics Middle Aged Original Tryptophan
ISSN:	0270-9139, 1527-3350, 1527-3350
Online Access:	Get full text
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