Standardized Infliximab Regimen to Treat Severe Central Nervous System Tuberculosis: A Case Series of 18 Patients

Abstract Background Morbidity associated with central nervous system tuberculosis (CNS TB) remains high due to persistent inflammation despite standard-of-care (SOC) treatment, including antituberculosis therapy and corticosteroids. Tumor necrosis factor alpha (TNF-α) is a key cytokine driving this...

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Vydané v:	Open forum infectious diseases Ročník 12; číslo 8; s. ofaf450
Hlavní autori:	Benhard, Johan, Monsel, Gentiane, Dubée, Vincent, Pavese, Patricia, Rasoldier, Vero, Garrait, Valérie, Talleux, Marie, Vuotto, Fanny, Gueneau, Romain, Pouget-Abadie, Xavier, Thy, Michael, Palacios, Christia, Bachir, Marwa, Djossou, Felix, Tunesi, Simone, Jachym, Mathilde Fréchet, Pourcher, Valérie, Veziris, Nicolas, Bourgarit, Anne
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	US Oxford University Press 01.08.2025
Predmet:	Life Sciences Meningitis Microbiology and Pathogenesis Morbidity Nervous system Tuberculosis Tumor necrosis factor-TNF central nervous system tuberculosis infliximab paradoxical reaction tuberculous meningitis TNF-α inhibitor
ISSN:	2328-8957, 2328-8957
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