The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies

The importance of tryptophan as a precursor for neuroactive compounds has long been acknowledged. The metabolism of tryptophan along the kynurenine pathway and its involvement in mental disorders is an emerging area in psychiatry. We performed a meta-analysis to examine the differences in kynurenine...

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Bibliographic Details
Published in:	Molecular psychiatry Vol. 26; no. 8; pp. 4158 - 4178
Main Authors:	Marx, Wolfgang, McGuinness, Amelia J, Rocks, Tetyana, Ruusunen, Anu, Cleminson, Jasmine, Walker, Adam J, Gomes-da-Costa, Susana, Lane, Melissa, Sanches, Marsal, Diaz, Alexandre P, Tseng, Ping-Tao, Lin, Pao-Yen, Berk, Michael, Clarke, Gerard, O'Neil, Adrienne, Jacka, Felice, Stubbs, Brendon, Carvalho, André F, Quevedo, João, Soares, Jair C, Fernandes, Brisa S
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.08.2021
Subjects:	Acids Bipolar Disorder Depressive Disorder, Major Emotional disorders Humans Kynurenic Acid Kynurenine Mental depression Mental disorders Meta-analysis Metabolism Metabolites Mood Mood disorders Neuroprotection Neurotoxicity Quinolinic acid Schizophrenia Serotonin Systematic review Tryptophan
ISSN:	1359-4184, 1476-5578, 1476-5578
Online Access:	Get full text
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