Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly

The molecular motor dynein concentrates at the kinetochore region of mitotic chromosomes in animals to accelerate spindle microtubule capture and to control spindle checkpoint signaling. In this study, we describe the molecular mechanism used by the Rod-Zw10-Zwilch complex and the adaptor Spindly to...

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Bibliographic Details
Published in:	The Journal of cell biology Vol. 216; no. 4; p. 943
Main Authors:	Gama, José B, Pereira, Cláudia, Simões, Patrícia A, Celestino, Ricardo, Reis, Rita M, Barbosa, Daniel J, Pires, Helena R, Carvalho, Cátia, Amorim, João, Carvalho, Ana X, Cheerambathur, Dhanya K, Gassmann, Reto
Format:	Journal Article
Language:	English
Published:	United States 03.04.2017
Subjects:	Animals Caenorhabditis elegans - metabolism Caenorhabditis elegans - physiology Carrier Proteins - metabolism Cell Cycle Proteins - metabolism Cell Line, Tumor Chromosomal Proteins, Non-Histone - metabolism Chromosome Segregation - physiology Dynactin Complex - metabolism Dyneins - metabolism HeLa Cells Humans Kinetochores - metabolism Kinetochores - physiology Microtubule-Associated Proteins - metabolism Microtubules - metabolism Microtubules - physiology Mitosis - physiology Spindle Apparatus - metabolism Spindle Apparatus - physiology Spindly kinetochore mitosis RZZ complex BICD2 dynein/dynactin
ISSN:	1540-8140, 1540-8140
Online Access:	Get more information
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