Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly

The molecular motor dynein concentrates at the kinetochore region of mitotic chromosomes in animals to accelerate spindle microtubule capture and to control spindle checkpoint signaling. In this study, we describe the molecular mechanism used by the Rod-Zw10-Zwilch complex and the adaptor Spindly to...

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Veröffentlicht in:	The Journal of cell biology Jg. 216; H. 4; S. 943
Hauptverfasser:	Gama, José B, Pereira, Cláudia, Simões, Patrícia A, Celestino, Ricardo, Reis, Rita M, Barbosa, Daniel J, Pires, Helena R, Carvalho, Cátia, Amorim, João, Carvalho, Ana X, Cheerambathur, Dhanya K, Gassmann, Reto
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 03.04.2017
Schlagworte:	Animals Caenorhabditis elegans - metabolism Caenorhabditis elegans - physiology Carrier Proteins - metabolism Cell Cycle Proteins - metabolism Cell Line, Tumor Chromosomal Proteins, Non-Histone - metabolism Chromosome Segregation - physiology Dynactin Complex - metabolism Dyneins - metabolism HeLa Cells Humans Kinetochores - metabolism Kinetochores - physiology Microtubule-Associated Proteins - metabolism Microtubules - metabolism Microtubules - physiology Mitosis - physiology Spindle Apparatus - metabolism Spindle Apparatus - physiology Spindly kinetochore mitosis RZZ complex BICD2 dynein/dynactin
ISSN:	1540-8140, 1540-8140
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