Inhibition of the Glycolysis Prevents the Cerebral Infarction Progression Through Decreasing the Lactylation Levels of LCP1

Cerebral infarction (CI), also known as ischemic stroke, has a high incidence rate and mortality rate. The purpose of this study was to investigate the potential effect and mechanism of Lymphocyte cytosolic protein 1 (LCP1) in the CI progression. The middle cerebral artery occlusion (MCAO) treated r...

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Bibliographic Details
Published in:	Molecular biotechnology Vol. 65; no. 8; pp. 1336 - 1345
Main Authors:	Zhang, Wei, Xu, Liang, Yu, Zhenfei, Zhang, Meiqi, Liu, Jingquan, Zhou, Jianming
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.08.2023 Springer Nature B.V
Subjects:	Acidification Animals Apoptosis Biochemistry Biological Techniques Biotechnology brain Brain Ischemia Cell Biology Cell proliferation Cell viability Cerebral blood flow Cerebral infarction Chemistry Chemistry and Materials Science Cholecystokinin Cycloheximide Flow cytometry Glucose Glycolysis Human Genetics Immunoprecipitation In vivo methods and tests Infarction Infarction, Middle Cerebral Artery - metabolism Ischemia lactic acid Lymphocytes Microfilament Proteins - metabolism Moisture content mortality Occlusion Original Paper Pheochromocytoma cells precipitin tests Protein Science Proteins Rats Stroke Water content Western blotting Glycolysis Cerebral infarction LCP1 Lactylation
ISSN:	1073-6085, 1559-0305, 1559-0305
Online Access:	Get full text
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