Filamentous influenza virus enters cells via macropinocytosis

Influenza virus is pleiomorphic, producing both spherical (100-nm-diameter) and filamentous (100-nm by 20-μm) virions. While the spherical virions are known to enter host cells through exploitation of clathrin-mediated endocytosis, the entry pathway for filamentous virions has not been determined, t...

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Bibliographic Details
Published in:	Journal of virology Vol. 86; no. 20; p. 10950
Main Authors:	Rossman, Jeremy S, Leser, George P, Lamb, Robert A
Format:	Journal Article
Language:	English
Published:	United States 01.10.2012
Subjects:	Animals Cell Line Dogs Endocytosis Endosomes - metabolism Endosomes - virology HEK293 Cells Hepatitis A virus - physiology Humans Influenza A Virus, H1N1 Subtype - physiology Microscopy, Electron Pinocytosis Protein Conformation Viral Fusion Proteins Viral Matrix Proteins - chemistry Viral Matrix Proteins - metabolism Virus Internalization
ISSN:	1098-5514, 1098-5514
Online Access:	Get more information
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