FABP4 and MMP9 levels identified as predictive factors for poor prognosis in patients with nonalcoholic fatty liver using data mining approaches and gene expression analysis

Nonalcoholic fatty liver (NAFLD) may progress to nonalcoholic steatohepatitis (NASH) and ultimately to cirrhosis and hepatocellular carcinoma (HCC). Prognostic markers for these conditions are poorly defined. The aim of this study was to identify predictive gene markers for the transition from NAFL...

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Vydáno v:	Scientific reports Ročník 9; číslo 1; s. 19785 - 16
Hlavní autoři:	Coilly, Audrey, Desterke, Christophe, Guettier, Catherine, Samuel, Didier, Chiappini, Franck
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 24.12.2019 Nature Publishing Group
Témata:	38/39 45 45/61 631/114/2407 692/4020/4021 Adult Aged Cirrhosis Data Mining Databases, Nucleic Acid Fatty acid-binding protein Fatty Acid-Binding Proteins - biosynthesis Fatty liver Female Food and Nutrition Gelatinase B Gene expression Gene Expression Profiling Gene Expression Regulation Hepatocellular carcinoma Humanities and Social Sciences Humans Life Sciences Liver cancer Liver cirrhosis Male Matrix metalloproteinase Matrix Metalloproteinase 9 - biosynthesis Metalloproteinase Middle Aged multidisciplinary Non-alcoholic Fatty Liver Disease - diagnosis Non-alcoholic Fatty Liver Disease - metabolism Non-alcoholic Fatty Liver Disease - pathology Oligonucleotide Array Sequence Analysis Predictive Value of Tests Prognosis Science Science (multidisciplinary) Steatosis Hepatology, Microarrays
ISSN:	2045-2322, 2045-2322
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