Diabetes and Associated Complications in the South Asian Population

The rising prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of diabetes due to biologic causes which are exacerbated by lifestyle and environmental factors. Furthermore, they experience significant morbidity and...

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Published in:Current cardiology reports Vol. 16; no. 5; p. 476
Main Authors: Shah, Arti, Kanaya, Alka M.
Format: Journal Article
Language:English
Published: Boston Springer US 01.05.2014
Subjects:
Adipose Tissue - metabolism
Asian Continental Ancestry Group
C-Reactive Protein - metabolism
Cardiology
Cardiovascular Diseases - ethnology
Cardiovascular Diseases - physiopathology
Cardiovascular Diseases - prevention & control
Diabetes and Cardiovascular Disease (S Malik
Diabetes Complications - ethnology
Diabetes Complications - etiology
Diabetes Complications - physiopathology
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - ethnology
Diabetes Mellitus, Type 2 - physiopathology
Diet
Female
Genetic Predisposition to Disease
Humans
Life Style - ethnology
Male
Medicine
Medicine & Public Health
Obesity - complications
Prevalence
Renal Insufficiency, Chronic - ethnology
Renal Insufficiency, Chronic - physiopathology
Renal Insufficiency, Chronic - prevention & control
Risk Factors
Section Editor
Sedentary Lifestyle
Socioeconomic Factors
Topical Collection on Diabetes and Cardiovascular Disease
Urbanization
Type 2 diabetes
Genetics of diabetes
Diabetes complications
Diabetes risk factors
South Asians
Diabetes prevention
ISSN:1523-3782, 1534-3170, 1534-3170
Online Access:Get full text
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Abstract The rising prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of diabetes due to biologic causes which are exacerbated by lifestyle and environmental factors. Furthermore, they experience significant morbidity and mortality from complications of diabetes, most notably coronary artery disease, cerebrovascular disease, and chronic kidney disease. Therefore, understanding the pathophysiology and genetics of diabetes risk factors and its associated complications in South Asians is paramount to curbing the diabetes epidemic. With this understanding, the appropriate screening, preventative and therapeutic strategies can be implemented and further developed. In this review, we discuss in detail the biologic and lifestyle factors that predispose South Asians to diabetes and review the epidemiology and pathophysiology of microvascular and macrovascular complications of diabetes in South Asians. We also review the ongoing and completed diabetes prevention and management studies in South Asians.
AbstractList The rising prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of diabetes due to biologic causes which are exacerbated by lifestyle and environmental factors. Furthermore, they experience significant morbidity and mortality from complications of diabetes, most notably coronary artery disease, cerebrovascular disease, and chronic kidney disease. Therefore, understanding the pathophysiology and genetics of diabetes risk factors and its associated complications in South Asians is paramount to curbing the diabetes epidemic. With this understanding, the appropriate screening, preventative and therapeutic strategies can be implemented and further developed. In this review, we discuss in detail the biologic and lifestyle factors that predispose South Asians to diabetes and review the epidemiology and pathophysiology of microvascular and macrovascular complications of diabetes in South Asians. We also review the ongoing and completed diabetes prevention and management studies in South Asians.
The increasing prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of diabetes due to biologic and lifestyle factors. Furthermore, they experience significant morbidity and mortality from complications of diabetes, most notably coronary artery disease, cerebrovascular disease and chronic kidney disease. Therefore, understanding the pathophysiology and genetics of diabetes risk factors and its associated complications in South Asians is paramount to curbing the diabetes epidemic. With this understanding, the appropriate screening, preventative and therapeutic strategies can be implemented and further developed. In this review, we discuss in detail the biologic and lifestyle factors that predispose South Asians to diabetes and review the epidemiology and pathophysiology of microvascular and macrovascular complications of diabetes in South Asians. We also review the ongoing and completed diabetes prevention and management studies in South Asians.
The rising prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of diabetes due to biologic causes which are exacerbated by lifestyle and environmental factors. Furthermore, they experience significant morbidity and mortality from complications of diabetes, most notably coronary artery disease, cerebrovascular disease, and chronic kidney disease. Therefore, understanding the pathophysiology and genetics of diabetes risk factors and its associated complications in South Asians is paramount to curbing the diabetes epidemic. With this understanding, the appropriate screening, preventative and therapeutic strategies can be implemented and further developed. In this review, we discuss in detail the biologic and lifestyle factors that predispose South Asians to diabetes and review the epidemiology and pathophysiology of microvascular and macrovascular complications of diabetes in South Asians. We also review the ongoing and completed diabetes prevention and management studies in South Asians.The rising prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of diabetes due to biologic causes which are exacerbated by lifestyle and environmental factors. Furthermore, they experience significant morbidity and mortality from complications of diabetes, most notably coronary artery disease, cerebrovascular disease, and chronic kidney disease. Therefore, understanding the pathophysiology and genetics of diabetes risk factors and its associated complications in South Asians is paramount to curbing the diabetes epidemic. With this understanding, the appropriate screening, preventative and therapeutic strategies can be implemented and further developed. In this review, we discuss in detail the biologic and lifestyle factors that predispose South Asians to diabetes and review the epidemiology and pathophysiology of microvascular and macrovascular complications of diabetes in South Asians. We also review the ongoing and completed diabetes prevention and management studies in South Asians.
ArticleNumber 476
Author Shah, Arti
Kanaya, Alka M.
Author_xml – sequence: 1
  givenname: Arti
  surname: Shah
  fullname: Shah, Arti
  organization: Department of Medicine, Division of Endocrinology, University of California
– sequence: 2
  givenname: Alka M.
  surname: Kanaya
  fullname: Kanaya, Alka M.
  email: alka.kanaya@ucsf.edu
  organization: Department of Medicine, Division of General Internal Medicine, University of California
BackLink https://www.ncbi.nlm.nih.gov/pubmed/24643902$$D View this record in MEDLINE/PubMed
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1534-3170
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Wed Oct 01 14:25:45 EDT 2025
Thu Apr 03 07:00:57 EDT 2025
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Issue 5
Keywords Type 2 diabetes
Genetics of diabetes
Diabetes complications
Diabetes risk factors
South Asians
Diabetes prevention
Language English
License http://www.springer.com/tdm
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PublicationDate 2014-05-01
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PublicationPlace Boston
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PublicationTitle Current cardiology reports
PublicationTitleAbbrev Curr Cardiol Rep
PublicationTitleAlternate Curr Cardiol Rep
PublicationYear 2014
Publisher Springer US
Publisher_xml – name: Springer US
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Snippet The rising prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of diabetes...
The increasing prevalence of diabetes in South Asians has significant health and economic implications. South Asians are predisposed to the development of...
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SubjectTerms Adipose Tissue - metabolism
Asian Continental Ancestry Group
C-Reactive Protein - metabolism
Cardiology
Cardiovascular Diseases - ethnology
Cardiovascular Diseases - physiopathology
Cardiovascular Diseases - prevention & control
Diabetes and Cardiovascular Disease (S Malik
Diabetes Complications - ethnology
Diabetes Complications - etiology
Diabetes Complications - physiopathology
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - ethnology
Diabetes Mellitus, Type 2 - physiopathology
Diet
Female
Genetic Predisposition to Disease
Humans
Life Style - ethnology
Male
Medicine
Medicine & Public Health
Obesity - complications
Prevalence
Renal Insufficiency, Chronic - ethnology
Renal Insufficiency, Chronic - physiopathology
Renal Insufficiency, Chronic - prevention & control
Risk Factors
Section Editor
Sedentary Lifestyle
Socioeconomic Factors
Topical Collection on Diabetes and Cardiovascular Disease
Urbanization
Title Diabetes and Associated Complications in the South Asian Population
URI https://link.springer.com/article/10.1007/s11886-014-0476-5
https://www.ncbi.nlm.nih.gov/pubmed/24643902
https://www.proquest.com/docview/1508943497
https://pubmed.ncbi.nlm.nih.gov/PMC4026332
Volume 16
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