SETD2: from chromatin modifier to multipronged regulator of the genome and beyond

Histone modifying enzymes play critical roles in many key cellular processes and are appealing proteins for targeting by small molecules in disease. However, while the functions of histone modifying enzymes are often linked to epigenetic regulation of the genome, an emerging theme is that these enzy...

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Bibliographic Details
Published in:	Cellular and molecular life sciences : CMLS Vol. 79; no. 6; p. 346
Main Authors:	Molenaar, Thom M., van Leeuwen, Fred
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01.06.2022 Springer Nature B.V
Subjects:	Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Chromatin Chromatin - genetics Chromatin - metabolism Enzymes Epigenesis, Genetic Epigenetics genome Genomes Histone H3 Histones Histones - genetics Histones - metabolism Life Sciences Lysine Methylation mRNA processing Protein Processing, Post-Translational - genetics Review Saccharomyces cerevisiae - metabolism Substrates Transcription Tubulin Tumors Yeast yeasts SETD2 Chromatin Transcription Set2 Histone methyltransferase H3K36 methylation Cancer
ISSN:	1420-682X, 1420-9071, 1420-9071
Online Access:	Get full text
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