Elucidating Methods for Isolation and Quantification of Exosomes: A Review

Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune response, tumor metastasis, etc. Studies have shown that these vesicles also have diagnostic and therapeutic roles for which their accurate de...

Full description

Saved in:
Bibliographic Details
Published in:Molecular biotechnology Vol. 63; no. 4; pp. 249 - 266
Main Authors: Kurian, Talitha Keren, Banik, Soumyabrata, Gopal, Dharshini, Chakrabarti, Shweta, Mazumder, Nirmal
Format: Journal Article
Language:English
Published: New York Springer US 01.04.2021
Springer Nature B.V
Subjects:
Biochemistry
Biological Techniques
Biomarkers
Biosynthesis
Biotechnology
Cell Biology
Chemistry
Chemistry and Materials Science
Communication
Electron microscopy
Exosomes
Extracellular vesicles
Flow cytometry
gel chromatography
Higher education
Human Genetics
Immune response
Immune system
Life sciences
Light scattering
Lipids
Metastases
Metastasis
Microfluidic devices
Microfluidics
Microscopy
Nanoparticles
neoplasms
Photon correlation spectroscopy
Plasma
Protein Science
Proteins
Review
Size exclusion chromatography
therapeutics
Ultracentrifugation
Ultrafiltration
Vesicles
Biomarkers
Diagnosis
Exosomes
Therapeutics
ISSN:1073-6085, 1559-0305, 1559-0305
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune response, tumor metastasis, etc. Studies have shown that these vesicles also have diagnostic and therapeutic roles for which their accurate detection and quantification is essential. Due to the complexity in size and structure of exosomes, even the gold standard methods face challenges. This comprehensive review discusses the various standard methods such as ultracentrifugation, ultrafiltration, size-exclusion chromatography, precipitation, immunoaffinity, and microfluidic technologies for the isolation of exosomes. The principle of isolation of each method is described, as well as their specific advantages and disadvantages. Quantification of exosomes by nanoparticle tracking analysis, flow cytometry, tunable resistive pulse sensing, electron microscopy, dynamic light scattering, and microfluidic devices are also described, along with the applications of exosomes in various biomedical domains.
AbstractList Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune response, tumor metastasis, etc. Studies have shown that these vesicles also have diagnostic and therapeutic roles for which their accurate detection and quantification is essential. Due to the complexity in size and structure of exosomes, even the gold standard methods face challenges. This comprehensive review discusses the various standard methods such as ultracentrifugation, ultrafiltration, size-exclusion chromatography, precipitation, immunoaffinity, and microfluidic technologies for the isolation of exosomes. The principle of isolation of each method is described, as well as their specific advantages and disadvantages. Quantification of exosomes by nanoparticle tracking analysis, flow cytometry, tunable resistive pulse sensing, electron microscopy, dynamic light scattering, and microfluidic devices are also described, along with the applications of exosomes in various biomedical domains.
Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune response, tumor metastasis, etc. Studies have shown that these vesicles also have diagnostic and therapeutic roles for which their accurate detection and quantification is essential. Due to the complexity in size and structure of exosomes, even the gold standard methods face challenges. This comprehensive review discusses the various standard methods such as ultracentrifugation, ultrafiltration, size-exclusion chromatography, precipitation, immunoaffinity, and microfluidic technologies for the isolation of exosomes. The principle of isolation of each method is described, as well as their specific advantages and disadvantages. Quantification of exosomes by nanoparticle tracking analysis, flow cytometry, tunable resistive pulse sensing, electron microscopy, dynamic light scattering, and microfluidic devices are also described, along with the applications of exosomes in various biomedical domains.
Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune response, tumor metastasis, etc. Studies have shown that these vesicles also have diagnostic and therapeutic roles for which their accurate detection and quantification is essential. Due to the complexity in size and structure of exosomes, even the gold standard methods face challenges. This comprehensive review discusses the various standard methods such as ultracentrifugation, ultrafiltration, size-exclusion chromatography, precipitation, immunoaffinity, and microfluidic technologies for the isolation of exosomes. The principle of isolation of each method is described, as well as their specific advantages and disadvantages. Quantification of exosomes by nanoparticle tracking analysis, flow cytometry, tunable resistive pulse sensing, electron microscopy, dynamic light scattering, and microfluidic devices are also described, along with the applications of exosomes in various biomedical domains.Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune response, tumor metastasis, etc. Studies have shown that these vesicles also have diagnostic and therapeutic roles for which their accurate detection and quantification is essential. Due to the complexity in size and structure of exosomes, even the gold standard methods face challenges. This comprehensive review discusses the various standard methods such as ultracentrifugation, ultrafiltration, size-exclusion chromatography, precipitation, immunoaffinity, and microfluidic technologies for the isolation of exosomes. The principle of isolation of each method is described, as well as their specific advantages and disadvantages. Quantification of exosomes by nanoparticle tracking analysis, flow cytometry, tunable resistive pulse sensing, electron microscopy, dynamic light scattering, and microfluidic devices are also described, along with the applications of exosomes in various biomedical domains.
Author Chakrabarti, Shweta
Kurian, Talitha Keren
Banik, Soumyabrata
Mazumder, Nirmal
Gopal, Dharshini
Author_xml – sequence: 1
  givenname: Talitha Keren
  surname: Kurian
  fullname: Kurian, Talitha Keren
  organization: Department of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education (MAHE)
– sequence: 2
  givenname: Soumyabrata
  orcidid: 0000-0002-2254-1428
  surname: Banik
  fullname: Banik, Soumyabrata
  organization: Department of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education (MAHE)
– sequence: 3
  givenname: Dharshini
  surname: Gopal
  fullname: Gopal, Dharshini
  organization: Department of Bioinformatics, Manipal School of Life Sciences, Manipal Academy of Higher Education (MAHE)
– sequence: 4
  givenname: Shweta
  surname: Chakrabarti
  fullname: Chakrabarti, Shweta
  organization: Department of Bioinformatics, Manipal School of Life Sciences, Manipal Academy of Higher Education (MAHE)
– sequence: 5
  givenname: Nirmal
  orcidid: 0000-0001-8068-6484
  surname: Mazumder
  fullname: Mazumder, Nirmal
  email: nirmaluva@gmail.com
  organization: Department of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education (MAHE)
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33492613$$D View this record in MEDLINE/PubMed
BookMark eNqFkUtv1TAQhS1URB_wB1igSGy6CYztOI5ZIFXVLRQVIRCsLcd2bl3l2sVOCv33TG9aHl2Ulcfj7xyN5-yTnZiiJ-Q5hVcUQL4ulAHnNTBaA3CAmj8ie1QIVeNN7GANktctdGKX7JdyAUiKhj8hu5w3irWU75EPq3G2wZkpxHX10U_nyZVqSLk6LWnEboqVia76PJs4hSHYpZWGavUzlbTx5U11VH3xV8H_eEoeD2Ys_tnteUC-nay-Hr-vzz69Oz0-OqutADnVzjLjOmN657FknXTb0jAloO8Ha5UU3jrBwTtg4CSqHBjKlfC0V54fkLeL7-Xcb9DDxymbUV_msDH5WicT9L8vMZzrdbrSUjXAG4oGh7cGOX2ffZn0JhTrx9FEn-aimRBUyRZwV_9Fmw6k4K1oEX15D71Ic464CaRUJ5VklCH14u_hf099lwgC3QLYnErJftA2TNut41_CqCnom_D1Er7GSPU2fH0jZfekd-4PivgiKgjHtc9_xn5A9Qsr3cGT
CitedBy_id crossref_primary_10_1007_s00432_023_05273_1
crossref_primary_10_1088_1748_605X_ad3cab
crossref_primary_10_3390_bios13080802
crossref_primary_10_1016_j_jconrel_2022_12_027
crossref_primary_10_1186_s13045_022_01305_4
crossref_primary_10_1016_j_cclet_2023_109335
crossref_primary_10_1039_D4NR03454F
crossref_primary_10_1016_j_cis_2025_103517
crossref_primary_10_1016_j_biochi_2021_10_009
crossref_primary_10_1097_DSS_0000000000003487
crossref_primary_10_1088_2632_959X_aceb7d
crossref_primary_10_1080_17435889_2024_2354159
crossref_primary_10_3390_separations8110204
crossref_primary_10_1186_s13287_024_03837_7
crossref_primary_10_3390_biology11030413
crossref_primary_10_1134_S1990747821050068
crossref_primary_10_3390_pharmaceutics17010051
crossref_primary_10_1515_cclm_2023_0610
crossref_primary_10_3389_fimmu_2023_1090416
crossref_primary_10_2147_IJN_S527637
crossref_primary_10_3389_fmed_2024_1488536
crossref_primary_10_14348_molcells_2022_2033
crossref_primary_10_3389_fonc_2024_1459178
crossref_primary_10_3390_biom11121857
crossref_primary_10_1016_j_bioactmat_2024_11_004
crossref_primary_10_3390_membranes12060550
crossref_primary_10_1016_j_jddst_2025_106844
crossref_primary_10_1016_j_exer_2021_108892
crossref_primary_10_1016_j_mtadv_2025_100623
crossref_primary_10_1002_jemt_24420
crossref_primary_10_1016_j_lfs_2024_122747
crossref_primary_10_3389_fonc_2025_1592006
crossref_primary_10_3390_cells12091339
crossref_primary_10_1016_j_cca_2025_120456
crossref_primary_10_3390_ijtm5030039
crossref_primary_10_1016_j_mtbio_2025_101613
crossref_primary_10_1007_s00216_022_04174_5
crossref_primary_10_3390_ijms241813835
crossref_primary_10_3389_fbioe_2024_1363742
crossref_primary_10_1016_j_jfma_2025_02_013
crossref_primary_10_1002_smll_202402434
crossref_primary_10_35516_jjps_v18i2_2631
crossref_primary_10_2147_JHC_S423043
crossref_primary_10_3390_biomedicines9081061
crossref_primary_10_3390_ijms23042310
crossref_primary_10_3389_fimmu_2025_1512480
crossref_primary_10_1186_s12943_022_01509_9
crossref_primary_10_1186_s12951_023_01973_5
crossref_primary_10_3390_ijms231911284
crossref_primary_10_3389_fcell_2024_1372847
crossref_primary_10_1038_s41392_025_02312_w
crossref_primary_10_3390_ijms22126507
crossref_primary_10_1016_j_aca_2021_339099
crossref_primary_10_3390_pharmaceutics16060709
crossref_primary_10_3390_gels10120762
crossref_primary_10_1016_j_biopha_2025_118548
crossref_primary_10_1016_j_ijpharm_2025_125923
crossref_primary_10_3389_fphar_2022_839790
crossref_primary_10_3389_fcvm_2021_723236
crossref_primary_10_4103_ijmr_ijmr_2344_22
crossref_primary_10_3390_biomedicines9060603
crossref_primary_10_3892_ijmm_2025_5576
crossref_primary_10_1016_j_lfs_2022_121103
crossref_primary_10_1016_j_jddst_2025_107453
crossref_primary_10_1016_j_jddst_2024_105571
crossref_primary_10_1002_mco2_70386
crossref_primary_10_3389_fimmu_2024_1485628
crossref_primary_10_3390_biomedicines9101373
crossref_primary_10_3390_ijms231810390
crossref_primary_10_3389_fpls_2023_1090026
crossref_primary_10_1208_s12249_024_02983_8
crossref_primary_10_1038_s41368_025_00370_y
crossref_primary_10_1016_j_ijbiomac_2025_140753
crossref_primary_10_1002_adbi_202500008
crossref_primary_10_1016_j_clim_2023_109237
crossref_primary_10_3389_fphar_2024_1432683
crossref_primary_10_1016_j_bbcan_2024_189238
crossref_primary_10_1186_s13287_023_03467_5
crossref_primary_10_3390_cells11020266
crossref_primary_10_1002_jobm_202400221
crossref_primary_10_3389_fonc_2025_1498733
crossref_primary_10_3390_ijms23158351
crossref_primary_10_1016_j_apsb_2025_03_008
crossref_primary_10_1002_mas_21749
crossref_primary_10_3389_fimmu_2021_754004
crossref_primary_10_1667_RADE_24_00078_1
crossref_primary_10_3390_ijms22073651
crossref_primary_10_1186_s12917_021_02960_4
crossref_primary_10_1002_jev2_70087
crossref_primary_10_1016_j_arr_2024_102359
crossref_primary_10_1002_elps_202200133
crossref_primary_10_1002_cyto_a_24854
crossref_primary_10_1080_14737175_2021_1965882
crossref_primary_10_1002_jev2_70007
crossref_primary_10_3390_biomedicines11071806
crossref_primary_10_1002_ppsc_202200130
crossref_primary_10_2147_IJN_S323671
crossref_primary_10_1016_j_ijbiomac_2025_146563
crossref_primary_10_1016_j_apmt_2024_102395
crossref_primary_10_1002_adfm_202407842
crossref_primary_10_1016_j_addr_2021_113843
crossref_primary_10_1007_s13402_023_00810_z
crossref_primary_10_3390_bios14060307
crossref_primary_10_1007_s12035_023_03365_0
crossref_primary_10_1080_01913123_2025_2507698
crossref_primary_10_3390_cells10061361
crossref_primary_10_1016_j_ijpharm_2022_122356
crossref_primary_10_2147_IJN_S453545
crossref_primary_10_3390_pharmaceutics17050654
crossref_primary_10_3389_fmicb_2021_712588
crossref_primary_10_1371_journal_pone_0315168
Cites_doi 10.1002/cyto.a.24193
10.1186/1471-2407-6-283
10.1021/acschemneuro.8b00469
10.1074/jbc.273.32.20121
10.1038/srep33641
10.1074/mcp.M111.012732
10.1007/978-1-4939-9841-8_13
10.7150/thno.18133
10.1038/s41467-016-0009-6
10.2147/IJN.S191313
10.1093/nar/gks832
10.1007/978-1-4939-6728-5_7
10.1016/j.bbalip.2013.04.011
10.1073/pnas.0507995103
10.1371/journal.pbio.1001874
10.4196/kjpp.2018.22.2.113
10.1016/j.plipres.2014.01.004
10.1007/s13238-015-0156-2
10.2741/4621
10.1016/j.bcmd.2005.08.005
10.1016/j.colsurfb.2018.02.006
10.1242/jcs.029884
10.1016/j.ymeth.2015.05.028
10.1038/s41598-018-37186-2
10.1186/s13287-018-0923-0
10.1007/s11051-014-2583-z
10.1039/C7LC00592J
10.1080/20013078.2020.1713526
10.1016/j.humimm.2003.08.344
10.1042/bj20031594
10.1084/jem.183.3.1161
10.1038/ncb1596
10.1165/rcmb.2003-0238OC
10.1021/acs.jproteome.8b00479
10.1371/journal.pone.0149866
10.3390/s150717649
10.1016/S0022-1759(00)00321-5
10.1002/jcp.1041470105
10.1016/j.pharmthera.2018.08.002
10.1016/0092-8674(83)90040-5
10.1111/j.1600-0854.2009.00920.x
10.1111/j.1365-2567.2012.03569.x
10.4049/jimmunol.166.12.7309
10.3402/jev.v5.30829
10.1681/ASN.2012101031
10.1371/annotation/c9e68857-cd7e-4b1c-9765-04f66d8237d0
10.1080/20013078.2017.1422674
10.3402/jev.v4.25530
10.1016/j.colsurfb.2011.05.013
10.4314/ajtcam.v10i6.9
10.1039/C6AN00892E
10.1002/0471143030.cb0322s30
10.4155/bio-2017-0271
10.3390/s150510481
10.1016/j.ygyno.2008.04.033
10.1021/ac500931f
10.3892/ijmm.2016.2759
10.3892/ol.2014.2373
10.1038/srep14664
10.1172/JCI81135
10.1016/j.yexcr.2012.10.006
10.1182/blood-2003-03-0871
10.1681/ASN.2018020115
10.3390/ijms17020170
10.1016/j.addr.2012.08.008
10.1021/acs.analchem.8b04008
10.1016/j.bios.2019.04.013
10.1038/nri855
10.3892/or.2016.5021
10.1016/j.bios.2020.112622
10.1021/ac5023056
10.1006/meth.2000.1039
10.1080/20013078.2018.1435138
10.3389/fcell.2020.00367
10.1002/biot.201600699
10.1007/s11095-010-0073-2
10.1016/j.scr.2013.01.002
10.1007/978-1-4939-7253-1_29
10.1016/j.jprot.2018.07.001
10.1021/acs.langmuir.5b01402
10.1083/jcb.147.3.599
10.1182/blood-2010-09-307595
10.1038/srep23978
10.1002/pros.23901
10.1038/sj.emboj.7601850
10.1038/srep37246
10.1039/C4LC00136B
10.1038/sj.leu.2404132
10.1038/ki.2012.256
10.1016/j.nano.2011.04.003
10.1182/blood.V94.11.3791
10.3402/jev.v3.23430
10.1016/j.jconrel.2014.12.041
10.1111/jth.14154
10.1186/s12917-018-1509-x
10.1016/j.gene.2014.08.041
10.1038/s41598-016-0001-8
10.1038/s42003-019-0435-1
10.1002/cyto.a.20886
10.1152/ajprenal.00434.2006
10.1080/08923973.2018.1533969
10.1016/j.snb.2018.09.121
10.3402/jev.v5.32570
10.1073/pnas.1709210114
10.1073/pnas.1804548115
10.3402/jev.v5.31242
10.1038/s41598-020-60619-w
10.1038/ki.2008.206
10.1007/978-1-4939-6728-5_2
10.1016/j.ymeth.2012.01.002
10.3390/ani9100717
10.1007/s00702-009-0288-8
10.15430/JCP.2016.21.3.194
10.1007/s13402-017-0335-7
10.2741/3528
10.1016/S0165-022X(01)00205-6
10.1074/jbc.M116.729202
10.1038/icb.2010.64
10.1038/ncomms1285
10.1111/j.1538-7836.2010.04074.x
10.3390/v7062770
10.1016/j.placenta.2016.12.002
10.1023/A:1010067107182
10.3389/fnut.2020.00022
10.1016/j.yexcr.2008.09.020
10.1016/bs.mie.2020.06.011
10.1021/jacs.9b13221
10.1016/j.ajog.2015.07.001
10.1083/jcb.97.2.329
10.1186/1479-5876-12-204
10.1158/0008-5472.CAN-16-0868
ContentType Journal Article
Copyright The Author(s) 2021
The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: The Author(s) 2021
– notice: The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID C6C
AAYXX
CITATION
NPM
3V.
7QL
7QO
7T7
7U9
7X7
7XB
88A
88E
88I
8AO
8FD
8FE
8FG
8FH
8FI
8FJ
8FK
ABJCF
ABUWG
AEUYN
AFKRA
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
C1K
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
L6V
LK8
M0S
M1P
M2P
M7N
M7P
M7S
P64
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
PTHSS
Q9U
7X8
7S9
L.6
5PM
DOI 10.1007/s12033-021-00300-3
DatabaseName Springer Nature Open Access Journals
CrossRef
PubMed
ProQuest Central (Corporate)
Bacteriology Abstracts (Microbiology B)
Biotechnology Research Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
Virology and AIDS Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Biology Database (Alumni Edition)
Medical Database (Alumni Edition)
Science Database (Alumni Edition)
ProQuest Pharma Collection
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Collection
ProQuest Hospital Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Materials Science & Engineering
ProQuest Central (Alumni)
ProQuest One Sustainability
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Technology Collection
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One
ProQuest Central
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
ProQuest Engineering Collection
Biological Sciences
ProQuest Health & Medical Collection
Medical Database
Science Database
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Engineering Database
Biotechnology and BioEngineering Abstracts
ProQuest Central Premium
ProQuest One Academic (New)
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic (retired)
ProQuest One Academic UKI Edition
Engineering Collection
ProQuest Central Basic
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
PubMed
ProQuest Central Student
ProQuest Central Essentials
SciTech Premium Collection
Environmental Sciences and Pollution Management
ProQuest One Applied & Life Sciences
ProQuest One Sustainability
Health Research Premium Collection
Natural Science Collection
Health & Medical Research Collection
Biological Science Collection
Industrial and Applied Microbiology Abstracts (Microbiology A)
ProQuest Central (New)
ProQuest Medical Library (Alumni)
Engineering Collection
Engineering Database
Virology and AIDS Abstracts
ProQuest Science Journals (Alumni Edition)
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
ProQuest Technology Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Engineering Research Database
ProQuest One Academic
ProQuest One Academic (New)
Technology Collection
Technology Research Database
ProQuest One Academic Middle East (New)
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Biology Journals (Alumni Edition)
ProQuest Central
ProQuest Health & Medical Research Collection
ProQuest Engineering Collection
Biotechnology Research Abstracts
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
AIDS and Cancer Research Abstracts
ProQuest Central Basic
ProQuest Science Journals
ProQuest SciTech Collection
ProQuest Medical Library
Materials Science & Engineering Collection
ProQuest Central (Alumni)
MEDLINE - Academic
AGRICOLA
AGRICOLA - Academic
DatabaseTitleList
AGRICOLA
PubMed
MEDLINE - Academic

ProQuest Central Student
CrossRef
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Engineering
Chemistry
Biology
EISSN 1559-0305
EndPage 266
ExternalDocumentID PMC7940341
33492613
10_1007_s12033_021_00300_3
Genre Journal Article
Review
GrantInformation_xml – fundername: Manipal Academy of Higher Education, Manipal
– fundername: Department of Science and Technology, Ministry of Science and Technology
  grantid: DST/INT/BLG/P-3/2019
  funderid: http://dx.doi.org/10.13039/501100001409
– fundername: Department of Science and Technology, Ministry of Science and Technology
  grantid: DST/INT/BLG/P-3/2019
– fundername: ;
– fundername: ;
  grantid: DST/INT/BLG/P-3/2019
GroupedDBID ---
-4Y
-56
-5G
-BR
-EM
-Y2
-~C
.86
.VR
06C
06D
0R~
0VY
123
1N0
2.D
203
28-
29M
2J2
2JN
2JY
2KG
2KM
2LR
2VQ
2~H
30V
3SX
3V.
4.4
406
408
40D
40E
53G
5VS
67N
6NX
7X7
88A
88E
88I
8AO
8FE
8FG
8FH
8FI
8FJ
8TC
8UJ
95-
95.
95~
96X
A8Z
AAAVM
AABHQ
AACDK
AAHBH
AAHNG
AAIAL
AAIKT
AAJBT
AAJKR
AANXM
AANZL
AARHV
AARTL
AASML
AATNV
AATVU
AAUYE
AAWCG
AAYIU
AAYQN
AAYTO
AAYZH
ABAKF
ABDZT
ABECU
ABFTV
ABHLI
ABHQN
ABJCF
ABJNI
ABJOX
ABKCH
ABMNI
ABMQK
ABNWP
ABQBU
ABQSL
ABSXP
ABTEG
ABTHY
ABTKH
ABTMW
ABUWG
ABWNU
ABXPI
ACAOD
ACBXY
ACCUX
ACDTI
ACGFS
ACGOD
ACHSB
ACHXU
ACIWK
ACKNC
ACMDZ
ACMLO
ACOKC
ACOMO
ACPIV
ACPRK
ACZOJ
ADBBV
ADHHG
ADHIR
ADINQ
ADKNI
ADKPE
ADMLS
ADRFC
ADTPH
ADURQ
ADYFF
ADZKW
AEBTG
AEFQL
AEGAL
AEGNC
AEJHL
AEJRE
AEKMD
AEMSY
AENEX
AEOHA
AEPYU
AESKC
AETLH
AEUYN
AEVLU
AEXYK
AFBBN
AFEXP
AFGCZ
AFKRA
AFLOW
AFQWF
AFRAH
AFWTZ
AFZKB
AGAYW
AGDGC
AGGDS
AGJBK
AGMZJ
AGQEE
AGQMX
AGRTI
AGWIL
AGWZB
AGYKE
AHAVH
AHBYD
AHKAY
AHMBA
AHSBF
AIAKS
AIGIU
AIIXL
AILAN
AITGF
AJBLW
AJRNO
AJZVZ
ALIPV
ALMA_UNASSIGNED_HOLDINGS
ALWAN
AMKLP
AMXSW
AMYLF
AMYQR
AOCGG
ARMRJ
ASPBG
AVWKF
AXYYD
AYJHY
AZFZN
AZQEC
B-.
BA0
BBNVY
BBWZM
BDATZ
BENPR
BGLVJ
BGNMA
BHPHI
BPHCQ
BVXVI
C6C
CAG
CCPQU
COF
CS3
CSCUP
DDRTE
DNIVK
DPUIP
DU5
DWQXO
EBD
EBLON
EBS
EIOEI
EJD
EMOBN
ESBYG
F5P
FEDTE
FERAY
FFXSO
FIGPU
FINBP
FNLPD
FRRFC
FSGXE
FWDCC
FYUFA
G-Y
G-Z
GGCAI
GGRSB
GJIRD
GNUQQ
GNWQR
GQ6
GQ7
H13
HCIFZ
HF~
HG6
HMCUK
HMJXF
HRMNR
HVGLF
HZ~
I-F
IJ-
IKXTQ
ITM
IWAJR
IZQ
I~X
I~Z
J-C
J0Z
JBSCW
JZLTJ
KOV
L6V
LK8
LLZTM
M0L
M1P
M2P
M4Y
M7P
M7S
MA-
ML0
N2Q
NB0
NDZJH
NF0
NPVJJ
NQJWS
NU0
O9-
O93
O9G
O9I
O9J
OVD
P19
P2P
PF0
PQQKQ
PROAC
PSQYO
PT4
PT5
PTHSS
Q2X
QOK
QOR
QOS
R4E
R89
R9I
RHV
RIG
RNI
ROL
RPX
RSV
RZK
S16
S1Z
S26
S27
S28
S3A
S3B
SAP
SBL
SCG
SCLPG
SDH
SDM
SHX
SISQX
SJYHP
SNE
SNPRN
SNX
SOHCF
SOJ
SPISZ
SRMVM
SSLCW
STPWE
SV3
SZN
T13
T16
TEORI
TSG
TSV
TUC
TUS
U2A
U9L
UG4
UKHRP
UOJIU
UTJUX
UZXMN
VC2
VFIZW
W48
WK6
WK8
YLTOR
Z7U
Z7V
Z7W
Z7X
Z7Y
Z82
Z87
Z8O
Z8P
Z8Q
Z8S
Z8V
Z91
ZMTXR
~EX
~KM
AAPKM
AAYXX
ABBRH
ABDBE
ABFSG
ABRTQ
ACSTC
ADHKG
AEZWR
AFDZB
AFFHD
AFHIU
AFOHR
AGQPQ
AHPBZ
AHWEU
AIXLP
ATHPR
AYFIA
CITATION
PHGZM
PHGZT
PJZUB
PPXIY
PQGLB
NPM
7QL
7QO
7T7
7U9
7XB
8FD
8FK
C1K
ESTFP
FR3
H94
K9.
M7N
P64
PKEHL
PQEST
PQUKI
Q9U
7X8
PUEGO
7S9
L.6
5PM
ID FETCH-LOGICAL-c507t-dc2ad8aabdedc2287dabdeda2950bbfcc975ecd530ed020d7507d0a1395e1b9e3
IEDL.DBID RSV
ISICitedReferencesCount 136
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000611412100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 1073-6085
1559-0305
IngestDate Tue Nov 04 01:59:42 EST 2025
Sun Nov 09 09:51:21 EST 2025
Mon Sep 08 05:33:04 EDT 2025
Wed Nov 05 02:02:11 EST 2025
Thu Apr 03 06:53:10 EDT 2025
Sat Nov 29 06:17:56 EST 2025
Tue Nov 18 22:43:18 EST 2025
Fri Feb 21 02:48:57 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 4
Keywords Biomarkers
Diagnosis
Exosomes
Therapeutics
Language English
License Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c507t-dc2ad8aabdedc2287dabdeda2950bbfcc975ecd530ed020d7507d0a1395e1b9e3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ORCID 0000-0002-2254-1428
0000-0001-8068-6484
OpenAccessLink https://link.springer.com/10.1007/s12033-021-00300-3
PMID 33492613
PQID 2498797212
PQPubID 55363
PageCount 18
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_7940341
proquest_miscellaneous_2551976054
proquest_miscellaneous_2480753656
proquest_journals_2498797212
pubmed_primary_33492613
crossref_citationtrail_10_1007_s12033_021_00300_3
crossref_primary_10_1007_s12033_021_00300_3
springer_journals_10_1007_s12033_021_00300_3
PublicationCentury 2000
PublicationDate 2021-04-01
PublicationDateYYYYMMDD 2021-04-01
PublicationDate_xml – month: 04
  year: 2021
  text: 2021-04-01
  day: 01
PublicationDecade 2020
PublicationPlace New York
PublicationPlace_xml – name: New York
– name: United States
– name: Totowa
PublicationTitle Molecular biotechnology
PublicationTitleAbbrev Mol Biotechnol
PublicationTitleAlternate Mol Biotechnol
PublicationYear 2021
Publisher Springer US
Springer Nature B.V
Publisher_xml – name: Springer US
– name: Springer Nature B.V
References Yang, Liao, Tian, Li (CR70) 2017; 12
Andaloussi, Lakhal, Mäger, Wood (CR3) 2013; 65
Morita, Sandrin, Chung, Morham, Gygi, Rodesch, Sundquist (CR37) 2007; 26
Rad, Pourfathollah, Yari, Mohammadi, Kheirandish (CR114) 2016; 30
Mallardi, Nuzziello, Liguori, Avolio, Palazzo (CR116) 2018; 168
Takahashi, Okada, Nagao, Kawamata, Hanyu, Yoshimoto, Takasugi, Watanabe, Kanemaki, Obuse, Hara (CR133) 2017; 8
Cheruvanky, Zhou, Pisitkun, Kopp, Knepper, Yuen, Star (CR57) 2007; 292
Meirelles, Nardi (CR134) 2009; 14
Sharma, Ludwig, Muller, Hong, Kirkwood, Ferrone, Whiteside (CR67) 2018; 7
Gurunathan, Kang, Jeyaraj, Qasim, Kim (CR9) 2019; 8
An, Wu, Zhu, Lubman (CR43) 2018; 17
Pospichalova, Svoboda, Dave, Kotrbova, Kaiser, Klemova, Ilkovics, Hampl, Crha, Jandakova, Minar (CR101) 2015; 4
Johnstone, Mathew, Mason, Teng (CR28) 1991; 147
Aygun, Urey, Ozkumur (CR90) 2019; 9
Daaboul, Gagni, Benussi, Bettotti, Ciani, Cretich, Freedman, Ghidoni, Ozkumur, Piotto, Prosperi (CR89) 2016; 6
Soo, Song, Zheng, Campbell, Riches, Gunn-Moore, Powis (CR92) 2012; 136
Daaboul, Reznik, Dhande, Deliwala, Freedman (CR130) 2018; 7
Hong, Muller, Boyiadzis, Whiteside (CR68) 2014; 9
Filipe, Hawe, Jiskoot (CR91) 2010; 27
Wang, Zou, Yang, Liu, Nie, Zheng, Cheng, Wang (CR126) 2019; 135
György, Módos, Pállinger, Pálóczi, Pásztói, Misják, Deli, Sipos, Szalai, Voszka, Polgár (CR76) 2011; 117
Avci, Ünlü, Özkumur, Ünlü (CR88) 2015; 15
Gámez-Valero, Monguió-Tortajada, Carreras-Planella, Beyer, Borràs (CR61) 2016; 6
Gleadle, McNicholas, Li, Michael, Rojas-Canales (CR93) 2018; 29
Kalluri (CR20) 2016; 126
Rollet-Cohen, Bourderioux, Lipecka, Chhuon, Jung, Mesbahi, Nguyen-Khoa, Guérin-Pfyffer, Schmitt, Edelman, Sermet-Gaudelus, Guerrera (CR111) 2018; 185
Théry, Amigorena, Raposo, Clayton (CR51) 2006; 30
Arslan, Lai, Smeets, Akeroyd, Choo, Aguor, Timmers, van Rijen, Doevendans, Pasterkamp, Lim (CR135) 2013; 10
Iljas, Guanzon, Elfeky, Rice, Salomon (CR141) 2017; 54
Kanchanapally, Deshmukh, Chavva, Tyagi, Srivastava, Patel, Singh, Singh (CR117) 2019; 14
Nguyen, Park, Kang, Kim (CR123) 2015; 15
Shearn, Aday, Ben-Aicha, Carnell-Morris, Siupa, Angelini, Clayton, Boulanger, Punjabi, Emanueli, Biglino (CR96) 2020; 8
Pan, Johnstone (CR27) 1983; 33
Anderson, Lane, Korbie, Trau (CR79) 2015; 31
Yang, Shen, Wang, Li, Zhang, Tao, Ding, Yu (CR129) 2018; 115
Laulagnier, Motta, Hamdi, Roy, Fauvelle, Pageaux, Kobayashi, Salles, Perret, Bonnerot, Record (CR34) 2004; 380
Parimon, Garrett, Chen, Antes (CR56) 2018; 141
Fang, Tian, Li, Jin, Li, Kong (CR118) 2017; 12
Koh, Almughlliq, Vaswani, Peiris, Mitchell (CR63) 2018; 23
Raposo, Nijman, Stoorvogel, Liejendekker, Harding, Melief, Geuze (CR136) 1996; 183
Alvarez, Khosroheidari, Ravi, DiStefano (CR47) 2012; 82
Aguilera-Rojas, Badewien-Rentzsch, Plendl, Kohn, Einspanier (CR94) 2018; 14
Musante, Bontha, La Salvia, Fernandez-Piñeros, Lannigan, Le, Mas, Erdbrügger (CR110) 2020; 10
Qin, Xu (CR148) 2014; 71
Pecora (CR82) 2000; 2
Dragovic, Gardiner, Brooks, Tannetta, Ferguson, Hole, Carr, Redman, Harris, Dobson, Harrison (CR73) 2011; 7
Salomon, Rice, Huckle (CR142) 2017
Hong, Funk, Muller, Boyiadzis, Whiteside (CR62) 2016; 5
Li, Kaslan, Lee, Yao, Gao (CR33) 2017; 7
Pakravan, Babashah, Sadeghizadeh, Mowla, Mossahebi-Mohammadi, Ataei, Dana, Javan (CR115) 2017; 40
Chahar, Bao, Casola (CR55) 2015; 7
Machida, Tomofuji, Maruyama, Yoneda, Ekuni, Azuma, Miyai, Mizuno, Kato, Tsutsumi, Uchida (CR143) 2016; 36
Mittelbrunn, Gutiérrez-Vázquez, Villarroya-Beltri, González, Sánchez-Cabo, González, Bernad, Sánchez-Madrid (CR42) 2011; 2
Xu, Simpson, Greening, Hill (CR58) 2017
Rider, Hurwitz, Meckes (CR46) 2016; 6
Ramshani, Zhang, Richards, Chen, Xu, Stiles, Hill, Senapati, Go, Chang (CR84) 2019; 2
Tanaka, Oikawa, Takanashi, Kudo, Ohyashiki, Ohyashiki, Kuroda (CR85) 2009; 4
Clayton, Court, Navabi, Adams, Mason, Hobot, Newman, Jasani (CR19) 2001; 247
Wollert, Yang, Ren, Lee, Im, Hurley (CR23) 2009; 122
Pols, Klumperman (CR32) 2009; 315
Ridder, Keller, Dams, Rupp, Schlaudraff, Del Turco, Starmann, Macas, Karpova, Devraj, Depboylu (CR35) 2014; 12
Bickmore, Miklavcic (CR108) 2020; 7
Ali Vistro, Liu, Xu, Yang, Haseeb, Huang, Bai, Yu, Gandahi, Tarique, Chen (CR109) 2019; 9
Valadi, Ekström, Bossios, Sjöstrand, Lee, Lötvall (CR41) 2007; 9
Zhang, Wang, Li, Liu, Li (CR53) 2014; 8
Contreras-Naranjo, Wu, Ugaz (CR49) 2017; 17
Théry, Zitvogel, Amigorena (CR29) 2002; 2
Jung, Mun (CR80) 2018; 131
Cao, Zhou, Zeng (CR119) 2019; 279
Borges, Melo, Özdemir, Kato, Revuelta, Miller, Gattone, LeBleu, Kalluri (CR131) 2013; 24
Li, Zhang, Li, Liu, Chu, Jiang, Hou, Zen, Zhang (CR145) 2015; 6
Joncas, Lucien, Rouleau, Morin, Leong, Pouliot, Fradet, Gilbert, Toren (CR113) 2019; 79
Eirin, Riester, Zhu, Tang, Evans, O'Brien, van Wijnen, Lerman (CR40) 2014; 551
Kornilov, Puhka, Mannerström, Hiidenmaa, Peltoniemi, Siljander, Seppänen-Kaijansinkko, Kaur (CR59) 2018; 7
Keryer-Bibens, Pioche-Durieu, Villemant, Souquère, Nishi, Hirashima, Middeldorp, Busson (CR16) 2006; 6
Böing, Van Der Pol, Grootemaat, Coumans, Sturk, Nieuwland (CR60) 2014; 3
Vogel, Coumans, Maltesen, Böing, Bonnington, Broekman, Broom, Buzás, Christiansen, Hajji, Kristensen (CR104) 2016; 5
Wiley, Gummuluru (CR139) 2006; 103
Theodoraki, Hong, Donnenberg, Donnenberg, Whiteside (CR98) 2020
Van Der Pol, Hoekstra, Sturk, Otto, Van Leeuwen, Nieuwland (CR25) 2010; 8
Maas, De Vrij, Van Der Vlist, Geragousian, Van Bloois, Mastrobattista, Schiffelers, Wauben, Broekman, Nolte (CR74) 2015; 200
Kwon, Oh, Nacke, Mostov, Lipschutz (CR13) 2016; 291
Weng, Sui, Shan, Hu, Chen, Zhang, Zhang (CR65) 2016; 141
Li, Rout, Xu, Pan, Tchounwou, Ma, Liu (CR120) 2018; 90
Haraszti, Didiot, Sapp, Leszyk, Shaffer, Rockwell, Gao, Narain, DiFiglia, Kiebish, Aronin (CR15) 2016; 5
Palmieri, Lucchetti, Gatto, Maiorana, Marcantoni, Maulucci, Papi, Pola, De Spirito, Sgambato (CR112) 2014; 16
Kim, Ahn, Kim, Kim, Kim, Kang (CR146) 2018; 22
Momen-Heravi, Getting, Moschos (CR1) 2018; 192
Crenshaw, Sims, Matthews (CR2) 2018
Orozco, Lewis (CR75) 2010; 77
Mitchell, Peiris, Kobayashi, Koh, Duncombe, Illanes, Rice, Salomon (CR132) 2015; 213
Wen, Sceneay, Lima, Wong, Becker, Krumeich, Lobb, Castillo, Wong, Ellis, Parker (CR138) 2016; 76
Sokolova, Ludwig, Hornung, Rotan, Horn, Epple, Giebel (CR137) 2011; 87
Zhou, Cheruvanky, Hu, Matsumoto, Hiramatsu, Cho, Berger, Leelahavanichkul, Doi, Chawla, Illei (CR14) 2008; 74
Muller, Mitsuhashi, Simms, Gooding, Whiteside (CR106) 2016; 6
Lin, Yu, Chen, Wang, Miao, Li, Zhang, Song, Cui (CR50) 2020; 16
Théry, Regnault, Garin, Wolfers, Zitvogel, Ricciardi-Castagnoli, Raposo, Amigorena (CR17) 1999; 147
Palmisano, Jensen, Le Bihan, Laine, McGuire, Pociot, Larsen (CR6) 2012; 11
Taylor, Gercel-Taylor (CR69) 2008; 110
Zhu, Wang, Cui, Liu, Bu, Ma, Wang, Gong, Lausted, Hood, Yang, Hu (CR127) 2014; 86
Llorente, Skotland, Sylvänne, Kauhanen, Róg, Orłowski, Vattulainen, Ekroos, Sandvig (CR36) 2013; 1831
Feng, Huang, Wani, Yu, Ashraf (CR45) 2014; 9
Zheng, Campbell, Lucocq, Riches, Powis (CR95) 2013; 319
Zarovni, Corrado, Guazzi, Zocco, Lari, Radano, Muhhina, Fondelli, Gavrilova, Chiesi (CR48) 2015; 87
Iwai, Minamisawa, Suga, Yajima, Shiba (CR54) 2016; 5
Waqas, Saqib, Rashid, Shah, Akhtar, Murtaza (CR149) 2013; 10
Ramos-Zayas, Franco-Molina, Hernádez-Granados, Zárate-Triviño, Coronado-Cerda, Mendoza-Gamboa, Zapata-Benavides, Ramírez-Romero, Santana-Krymskaya, Tamez-Guerra, Rodríguez-Padilla (CR107) 2019; 41
Wu, Ouyang, Wang, Zhang, Huang, Chen, Li, Li, Quinn, Dao, Suresh (CR71) 2017; 114
Buschow, Van Balkom, Aalberts, Heck, Wauben, Stoorvogel (CR10) 2010; 88
Buschow, Liefhebber, Wubbolts, Stoorvogel (CR18) 2005; 35
Deregibus, Figliolini, D'antico, S., Manzini, P.M., Pasquino, C., De Lena, M., Tetta, C., Brizzi, M.F. and Camussi, G. (CR64) 2016; 38
Zhang, Luo, He, Zhang, Cheng, Wu (CR147) 2009; 36
Bard, Hegmans, Hemmes, Luider, Willemsen, Severijnen, van Meerbeeck, Burgers, Hoogsteden, Lambrecht (CR24) 2004; 31
Kanwar, Dunlay, Simeone, Nagrath (CR72) 2014; 14
Stuffers, Sem Wegner, Stenmark, Brech (CR30) 2009; 10
Welsh, Van Der Pol, Arkesteijn, Bremer, Brisson, Coumans, Dignat-George, Duggan, Ghiran, Giebel, Görgens (CR100) 2020; 9
Duo, Bruno, Kozhich, David-Brown, Luo, Kwok, Santockyte, Haulenbeek, Liu, Hamuro, Peterson, Piccoli, DeSilva, Pillutla, Zhang (CR124) 2018; 10
De Gassart, Géminard, Février, Raposo, Vidal (CR12) 2003; 102
Akers, Ramakrishnan, Nolan, Duggan, Fu, Hochberg, Chen, Carter (CR81) 2016; 11
Rim, Kim (CR99) 2016; 21
CR97
Ratajczak, Miekus, Kucia, Zhang, Reca, Dvorak, Ratajczak (CR144) 2006; 20
Sarker, Scholz-Romero, Perez, Illanes, Mitchell, Rice, Salomon (CR140) 2014; 12
Sina, Vaidyanathan, Dey, Carrascosa, Shiddiky, Trau (CR128) 2016; 6
Guescini, Genedani, Stocchi, Agnati (CR38) 2010; 117
Liang, Sheng, Zhou, Inci, Li, Demirci, Wang (CR83) 2017; 1660
Rupert, Lässer, Eldh, Block, Zhdanov, Lotvall, Bally, Höök (CR125) 2014; 86
Gupta, Rawat, Arora, Kottarath, Dinda, Vaishnav, Nayak, Mohanty (CR52) 2018; 9
Kalra, Drummen, Mathivanan (CR8) 2016; 17
Tauro, Greening, Mathias, Ji, Mathivanan, Scott, Simpson (CR21) 2012; 56
Gallart-Palau, Serra, Wong, Sandin, Lai, Chen, Kon, Sze (CR66) 2015; 5
Wang, Senapati, Chang (CR121) 2020; 41
Libregts, Arkesteijn, Németh, Noltet Hoen, Wauben (CR77) 2020; 16
Heijnen, Schiel, Fijnheer, Geuze, Sixma (CR5) 1999; 94
Maas, Broekman, de Vrij, Hill (CR78) 2017
Harding, Heuser, Stahl (CR26) 1983; 97
Castro, Prieto, Silva (CR31) 2014; 54
Barreiro, Huber, Holthofer, Gnudi, Long (CR44) 2020
Maas, De Vrij, Broekman (CR102) 2014; 92
Riteau, Faure, Menier, Viel, Carosella, Amigorena, Rouas-Freiss (CR22) 2003; 64
Yuan, Li (CR4) 2019; 10
Zhang, Hatamie, Ewing (CR103) 2020; 142
Mullett, Lai, Yeung (CR86) 2000; 22
Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze (CR11) 1998; 273
Bellingham, Coleman, Hill (CR39) 2012; 40
Catimel, Rothacker, Nice (CR87) 2001; 49
Bogomolny, Hong, Blenkiron, Simonov, Dauros, Swift, Phillips, Willmott, Parak, Osinski, Liang (CR105) 2015
Théry, Boussac, Véron, Ricciardi-Castagnoli, Raposo, Garin, Amigorena (CR7) 2001; 166
Kashefi-Kheyrabadi, Kim, Chakravarty, Park, Gwak, Kim, Mohammadniaei, Lee, Hyun, Jung (CR122) 2020; 169
MK Waqas (300_CR149) 2013; 10
R Xu (300_CR58) 2017
A Llorente (300_CR36) 2013; 1831
F Rad (300_CR114) 2016; 30
Y Weng (300_CR65) 2016; 141
Z Zhang (300_CR53) 2014; 8
L Muller (300_CR106) 2016; 6
A Gámez-Valero (300_CR61) 2016; 6
K Laulagnier (300_CR34) 2004; 380
M Aguilera-Rojas (300_CR94) 2018; 14
MN Theodoraki (300_CR98) 2020
U Aygun (300_CR90) 2019; 9
AN Böing (300_CR60) 2014; 3
BJ Crenshaw (300_CR2) 2018
BT Pan (300_CR27) 1983; 33
G Daaboul (300_CR130) 2018; 7
L Kashefi-Kheyrabadi (300_CR122) 2020; 169
Z Ramshani (300_CR84) 2019; 2
K Iwai (300_CR54) 2016; 5
JD Iljas (300_CR141) 2017; 54
V Filipe (300_CR91) 2010; 27
RA Haraszti (300_CR15) 2016; 5
C Théry (300_CR29) 2002; 2
JA Welsh (300_CR100) 2020; 9
BJ Tauro (300_CR21) 2012; 56
W Ali Vistro (300_CR109) 2019; 9
J Li (300_CR145) 2015; 6
S Sarker (300_CR140) 2014; 12
MK Jung (300_CR80) 2018; 131
SI Buschow (300_CR18) 2005; 35
M Guescini (300_CR38) 2010; 117
C Théry (300_CR51) 2006; 30
C Harding (300_CR26) 1983; 97
RA Dragovic (300_CR73) 2011; 7
FH Joncas (300_CR113) 2019; 79
RM Johnstone (300_CR28) 1991; 147
P Li (300_CR33) 2017; 7
K Ridder (300_CR35) 2014; 12
R Kornilov (300_CR59) 2018; 7
V Rollet-Cohen (300_CR111) 2018; 185
B György (300_CR76) 2011; 117
SL Meirelles (300_CR134) 2009; 14
O Avci (300_CR88) 2015; 15
T Parimon (300_CR56) 2018; 141
HS Chahar (300_CR55) 2015; 7
SH Kwon (300_CR13) 2016; 291
S Stuffers (300_CR30) 2009; 10
R Pecora (300_CR82) 2000; 2
HH Nguyen (300_CR123) 2015; 15
HF Heijnen (300_CR5) 1999; 94
A Mallardi (300_CR116) 2018; 168
T Wollert (300_CR23) 2009; 122
M Tanaka (300_CR85) 2009; 4
300_CR97
YQ Koh (300_CR63) 2018; 23
SS Kanwar (300_CR72) 2014; 14
E Morita (300_CR37) 2007; 26
DL Rupert (300_CR125) 2014; 86
L Zhu (300_CR127) 2014; 86
R Kanchanapally (300_CR117) 2019; 14
F Yang (300_CR70) 2017; 12
A Clayton (300_CR19) 2001; 247
A Takahashi (300_CR133) 2017; 8
L Musante (300_CR110) 2020; 10
W Anderson (300_CR79) 2015; 31
SE Andaloussi (300_CR3) 2013; 65
XW Zhang (300_CR103) 2020; 142
SL Maas (300_CR78) 2017
T Machida (300_CR143) 2016; 36
B Catimel (300_CR87) 2001; 49
M An (300_CR43) 2018; 17
V Palmieri (300_CR112) 2014; 16
G Palmisano (300_CR6) 2012; 11
A Cheruvanky (300_CR57) 2007; 292
Y Zheng (300_CR95) 2013; 319
SL Maas (300_CR102) 2014; 92
P Sharma (300_CR67) 2018; 7
A Eirin (300_CR40) 2014; 551
N Zarovni (300_CR48) 2015; 87
AF Orozco (300_CR75) 2010; 77
MP Bard (300_CR24) 2004; 31
Q Wang (300_CR126) 2019; 135
V Pospichalova (300_CR101) 2015; 4
H Valadi (300_CR41) 2007; 9
K Pakravan (300_CR115) 2017; 40
LG Liang (300_CR83) 2017; 1660
S Gurunathan (300_CR9) 2019; 8
BM Castro (300_CR31) 2014; 54
GG Daaboul (300_CR89) 2016; 6
S Gupta (300_CR52) 2018; 9
M Mittelbrunn (300_CR42) 2011; 2
K Barreiro (300_CR44) 2020
S Lin (300_CR50) 2020; 16
M Wu (300_CR71) 2017; 114
Y Yang (300_CR129) 2018; 115
CY Soo (300_CR92) 2012; 136
DD Taylor (300_CR69) 2008; 110
R Kalluri (300_CR20) 2016; 126
R Vogel (300_CR104) 2016; 5
E Bogomolny (300_CR105) 2015
H Zhou (300_CR14) 2008; 74
KT Rim (300_CR99) 2016; 21
S Fang (300_CR118) 2017; 12
CS Hong (300_CR68) 2014; 9
E Van Der Pol (300_CR25) 2010; 8
C Keryer-Bibens (300_CR16) 2006; 6
DC Bickmore (300_CR108) 2020; 7
AI Shearn (300_CR96) 2020; 8
C Théry (300_CR17) 1999; 147
Y Zhang (300_CR147) 2009; 36
X Li (300_CR120) 2018; 90
C Théry (300_CR7) 2001; 166
F Momen-Heravi (300_CR1) 2018; 192
MC Deregibus (300_CR64) 2016; 38
JC Contreras-Naranjo (300_CR49) 2017; 17
JC Akers (300_CR81) 2016; 11
YS Kim (300_CR146) 2018; 22
J Gleadle (300_CR93) 2018; 29
WM Mullett (300_CR86) 2000; 22
J Duo (300_CR124) 2018; 10
C Wang (300_CR121) 2020; 41
L Yuan (300_CR4) 2019; 10
J Qin (300_CR148) 2014; 71
MD Mitchell (300_CR132) 2015; 213
SW Wen (300_CR138) 2016; 76
Y Ramos-Zayas (300_CR107) 2019; 41
G Raposo (300_CR136) 1996; 183
H Cao (300_CR119) 2019; 279
J Ratajczak (300_CR144) 2006; 20
AA Sina (300_CR128) 2016; 6
FT Borges (300_CR131) 2013; 24
C Salomon (300_CR142) 2017
H Kalra (300_CR8) 2016; 17
SI Buschow (300_CR10) 2010; 88
MA Rider (300_CR46) 2016; 6
F Arslan (300_CR135) 2013; 10
MJ Kleijmeer (300_CR11) 1998; 273
X Gallart-Palau (300_CR66) 2015; 5
CS Hong (300_CR62) 2016; 5
RD Wiley (300_CR139) 2006; 103
ML Alvarez (300_CR47) 2012; 82
SL Maas (300_CR74) 2015; 200
V Sokolova (300_CR137) 2011; 87
A De Gassart (300_CR12) 2003; 102
SFWM Libregts (300_CR77) 2020; 16
B Riteau (300_CR22) 2003; 64
Y Feng (300_CR45) 2014; 9
SA Bellingham (300_CR39) 2012; 40
MS Pols (300_CR32) 2009; 315
References_xml – volume: 319
  start-page: 1706
  year: 2013
  end-page: 1713
  ident: CR95
  article-title: Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis
  publication-title: Experimental Cell Research
– volume: 12
  start-page: 1
  year: 2017
  end-page: 13
  ident: CR118
  article-title: Clinical application of a microfluidic chip for immunocapture and quantification of circulating exosomes to assist breast cancer diagnosis and molecular classification
  publication-title: PLoS ONE
– volume: 122
  start-page: 2163
  issue: 13
  year: 2009
  end-page: 2166
  ident: CR23
  article-title: The ESCRT machinery at a glance
  publication-title: Journal of cell science
– volume: 117
  start-page: 1
  year: 2010
  end-page: 4
  ident: CR38
  article-title: Astrocytes and glioblastoma cells release exosomes carrying mtDNA
  publication-title: Journal of Neural Transmission
– ident: CR97
– volume: 14
  start-page: 1
  year: 2018
  end-page: 9
  ident: CR94
  article-title: Exploration of serum-and cell culture-derived exosomes from dogs
  publication-title: BMC Veterinary Research
– volume: 4
  start-page: 1
  year: 2015
  end-page: 15
  ident: CR101
  article-title: Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer
  publication-title: Journal of Extracellular Vesicles
– volume: 7
  start-page: 789
  year: 2017
  end-page: 804
  ident: CR33
  article-title: Progress in exosome isolation techniques
  publication-title: Theranostics
– volume: 6
  start-page: 1
  year: 2006
  end-page: 8
  ident: CR16
  article-title: Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9
  publication-title: BMC Cancer
– volume: 3
  start-page: 1
  year: 2014
  end-page: 11
  ident: CR60
  article-title: Single-step isolation of extracellular vesicles by size-exclusion chromatography
  publication-title: Journal of Extracellular Vesicles
– volume: 11
  start-page: 230
  year: 2012
  end-page: 243
  ident: CR6
  article-title: Characterization of membrane-shed microvesicles from cytokine-stimulated β-cells using proteomics strategies
  publication-title: Molecular and Cellular Proteomics
– volume: 54
  start-page: 53
  year: 2014
  end-page: 67
  ident: CR31
  article-title: Ceramide: A simple sphingolipid with unique biophysical properties
  publication-title: Progress in Lipid Research
– volume: 4
  start-page: 1
  year: 2009
  end-page: 5
  ident: CR85
  article-title: Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients
  publication-title: PLoS ONE
– volume: 169
  start-page: 1
  year: 2020
  end-page: 9
  ident: CR122
  article-title: Detachable microfluidic device implemented with electrochemical aptasensor (DeMEA) for sequential analysis of cancerous exosomes
  publication-title: Biosensors and Bioelectronics
– volume: 17
  start-page: 1
  year: 2016
  end-page: 30
  ident: CR8
  article-title: Focus on extracellular vesicles: Introducing the next small big thing
  publication-title: International Journal of Molecular Sciences
– volume: 2
  start-page: 1
  year: 2011
  end-page: 10
  ident: CR42
  article-title: Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
  publication-title: Nature Communications
– volume: 5
  start-page: 1
  year: 2016
  end-page: 17
  ident: CR54
  article-title: Isolation of human salivary extracellular vesicles by iodixanol density gradient ultracentrifugation and their characterizations
  publication-title: Journal of Extracellular Vesicles
– volume: 147
  start-page: 599
  year: 1999
  end-page: 610
  ident: CR17
  article-title: Molecular characterization of dendritic cell-derived exosomes: Selective accumulation of the heat shock protein hsc73
  publication-title: The Journal of Cell Biology
– volume: 5
  start-page: 1
  year: 2016
  end-page: 13
  ident: CR104
  article-title: A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing
  publication-title: Journal of Extracellular Vesicles
– volume: 14
  start-page: 4281
  year: 2009
  end-page: 4298
  ident: CR134
  article-title: Methodology, biology and clinical applications of mesenchymal stem cells
  publication-title: Frontiers in Bioscience (Landmark Edition)
– volume: 7
  start-page: 1
  year: 2020
  end-page: 7
  ident: CR108
  article-title: Characterization of extracellular vesicles isolated from human milk using a precipitation-based method
  publication-title: Frontiers in Nutrition
– volume: 10
  start-page: 964
  year: 2019
  end-page: 972
  ident: CR4
  article-title: Exosomes in Parkinson’s disease: Current perspectives and future challenges
  publication-title: ACS Chemical Neuroscience
– year: 2018
  ident: CR2
  publication-title: Biological function of exosomes as diagnostic markers and therapeutic delivery vehicles in carcinogenesis and infectious diseases
– volume: 2
  start-page: 123
  year: 2000
  end-page: 131
  ident: CR82
  article-title: Dynamic light scattering measurement of nanometer particles in liquids
  publication-title: Journal of Nanoparticle Research
– volume: 102
  start-page: 4336
  year: 2003
  end-page: 4344
  ident: CR12
  article-title: Lipid raft-associated protein sorting in exosomes
  publication-title: Blood
– volume: 41
  start-page: 1
  year: 2020
  end-page: 15
  ident: CR121
  article-title: Liquid biopsy technologies based on membrane microfluidics: High-yield purification and selective quantification of biomarkers in nanocarriers
  publication-title: Electrophoresis
– volume: 20
  start-page: 847
  year: 2006
  end-page: 856
  ident: CR144
  article-title: Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: Evidence for horizontal transfer of mRNA and protein delivery
  publication-title: Leukemia
– volume: 1660
  start-page: 355
  year: 2017
  end-page: 364
  ident: CR83
  article-title: An integrated double-filtration microfluidic device for detection of extracellular vesicles from urine for bladder cancer diagnosis
  publication-title: Methods in Molecular Biology
– year: 2020
  ident: CR98
  article-title: Evaluation of exosome proteins by on-bead flow cytometry
  publication-title: Cytometry Part A
  doi: 10.1002/cyto.a.24193
– volume: 273
  start-page: 20121
  year: 1998
  end-page: 20127
  ident: CR11
  article-title: Selective enrichment of tetraspanin proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
  publication-title: Journal of Biological Chemistry
– volume: 7
  start-page: 780
  year: 2011
  end-page: 788
  ident: CR73
  article-title: Sizing and phenotyping of cellular vesicles using nanoparticle tracking analysis
  publication-title: Nanomedicine: Nanotechnology, Biology and Medicine
– volume: 315
  start-page: 1584
  year: 2009
  end-page: 1592
  ident: CR32
  article-title: Trafficking and function of the tetraspanin CD63
  publication-title: Experimental Cell Research
– volume: 291
  start-page: 25462
  year: 2016
  end-page: 25475
  ident: CR13
  article-title: Adaptor protein CD2AP and L-type lectin LMAN2 regulate exosome cargo protein trafficking through the Golgi complex
  publication-title: Journal of Biological Chemistry
– volume: 200
  start-page: 87
  year: 2015
  end-page: 96
  ident: CR74
  article-title: Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics
  publication-title: Journal of Controlled Release
– volume: 79
  start-page: 1767
  year: 2019
  end-page: 1776
  ident: CR113
  article-title: Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients
  publication-title: The Prostate
– start-page: 21
  year: 2017
  end-page: 33
  ident: CR78
  article-title: Tunable resistive pulse sensing for the characterization of extracellular vesicles
  publication-title: Exosomes and microvesicles
– volume: 40
  start-page: 457
  year: 2017
  end-page: 470
  ident: CR115
  article-title: MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in breast cancer cells
  publication-title: Cellular Oncology
– volume: 88
  start-page: 851
  year: 2010
  end-page: 856
  ident: CR10
  article-title: MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
  publication-title: Immunology and Cell Biology
– volume: 40
  start-page: 10937
  year: 2012
  end-page: 10949
  ident: CR39
  article-title: Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
  publication-title: Nucleic Acids Research
– volume: 9
  start-page: 1
  year: 2019
  end-page: 8
  ident: CR90
  article-title: Label-free detection of nanoparticles using depth scanning correlation interferometric microscopy
  publication-title: Scientific Reports
– volume: 56
  start-page: 293
  year: 2012
  end-page: 304
  ident: CR21
  article-title: Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
  publication-title: Methods
– volume: 94
  start-page: 3791
  year: 1999
  end-page: 3799
  ident: CR5
  article-title: Activated platelets release two types of membrane vesicles: Microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and granules
  publication-title: Blood
– volume: 16
  start-page: 1
  year: 2020
  end-page: 18
  ident: CR50
  article-title: Progress in microfluidics-based exosome separation and detection technologies for diagnostic applications
  publication-title: Small (Weinheim an der Bergstrasse, Germany)
– volume: 54
  start-page: 76
  year: 2017
  end-page: 82
  ident: CR141
  article-title: Bio-compartmentalization of microRNAs in exosomes during gestational diabetes mellitus
  publication-title: Placenta
– volume: 166
  start-page: 7309
  year: 2001
  end-page: 7318
  ident: CR7
  article-title: Proteomic analysis of dendritic cell-derived exosomes: A secreted subcellular compartment distinct from apoptotic vesicles
  publication-title: The Journal of Immunology
– start-page: 163
  year: 2017
  end-page: 179
  ident: CR142
  article-title: Role of exosomes in placental homeostasis and pregnancydisorders
  publication-title: Progressinmolecularbiologyandtranslationalscience
– volume: 247
  start-page: 163
  year: 2001
  end-page: 174
  ident: CR19
  article-title: Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry
  publication-title: Journal of Immunological Methods
– volume: 17
  start-page: 3599
  issue: 10
  year: 2018
  end-page: 3605
  ident: CR43
  article-title: Comparison of an optimized ultracentrifugation method versus size-exclusion chromatography for isolation of exosomes from human serum
  publication-title: Journal of Proteome Research
– volume: 26
  start-page: 4215
  year: 2007
  end-page: 4227
  ident: CR37
  article-title: Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis
  publication-title: The EMBO Journal
– volume: 23
  start-page: 865
  year: 2018
  end-page: 874
  ident: CR63
  article-title: Exosome enrichment by ultracentrifugation and size exclusion chromatography
  publication-title: Frontiers in Bioscience
– volume: 168
  start-page: 134
  year: 2018
  end-page: 142
  ident: CR116
  article-title: Counting of peripheral extracellular vesicles in multiple sclerosis patients by an improved nanoplasmonic assay and dynamic light scattering
  publication-title: Colloids and Surfaces B: Biointerfaces
– volume: 8
  start-page: 1
  year: 2017
  end-page: 14
  ident: CR133
  article-title: Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
  publication-title: Nature Communications
– volume: 292
  start-page: 1657
  year: 2007
  end-page: 1661
  ident: CR57
  article-title: Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator
  publication-title: American Journal of Physiology-Renal Physiology
– volume: 10
  start-page: 559
  year: 2018
  end-page: 576
  ident: CR124
  article-title: Surface plasmon resonance as a tool for ligand-binding assay reagent characterization in bioanalysis of biotherapeutics
  publication-title: Bioanalysis
– volume: 142
  start-page: 4093
  year: 2020
  end-page: 4097
  ident: CR103
  article-title: Simultaneous quantification of vesicle size and catecholamine content by resistive pulses in nanopores and vesicle impact electrochemical cytometry
  publication-title: Journal of the American Chemical Society
– volume: 126
  start-page: 1208
  year: 2016
  end-page: 1215
  ident: CR20
  article-title: The biology and function of exosomes in cancer
  publication-title: The Journal of Clinical Investigation
– volume: 9
  start-page: 1
  year: 2019
  end-page: 12
  ident: CR109
  article-title: Mitochondria-rich cells: A novel type of concealed cell in the small intestine of chinese soft-shelled turtles ( )
  publication-title: Animals
– volume: 135
  start-page: 129
  year: 2019
  end-page: 136
  ident: CR126
  article-title: Direct quantification of cancerous exosomes via surface plasmon resonance with dual gold nanoparticle-assisted signal amplification
  publication-title: Biosensors and Bioelectronics
– volume: 27
  start-page: 796
  year: 2010
  end-page: 810
  ident: CR91
  article-title: Critical evaluation of nanoparticle tracking analysis (NTA) by nanosight for the measurement of nanoparticles and protein aggregates
  publication-title: Pharmaceutical Research
– volume: 8
  start-page: 1701
  year: 2014
  end-page: 1706
  ident: CR53
  article-title: Comparison of ultracentrifugation and density gradient separation methods for isolating Tca8113 human tongue cancer cell line-derived exosomes
  publication-title: Oncology Letters
– volume: 12
  start-page: 1
  year: 2014
  end-page: 19
  ident: CR140
  article-title: Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy
  publication-title: Journal of Translational Medicine
– volume: 22
  start-page: 113
  year: 2018
  end-page: 125
  ident: CR146
  article-title: The potential theragnostic (diagnostic+therapeutic) application of exosomes in diverse biomedical fields
  publication-title: The Korean Journal of Physiology and Pharmacology
– volume: 31
  start-page: 114
  year: 2004
  end-page: 121
  ident: CR24
  article-title: Proteomic analysis of exosomes isolated from human malignant pleural effusions
  publication-title: American Journal of Respiratory Cell and Molecular Biology
– volume: 29
  start-page: 1784
  year: 2018
  end-page: 1784
  ident: CR93
  article-title: Nanoparticle tracking analysis of urine to detect exosomes can be confounded by albuminuria
  publication-title: Journal of the American Society of Nephrology
– volume: 213
  start-page: 173
  year: 2015
  end-page: 181
  ident: CR132
  article-title: Placental exosomes in normal and complicated pregnancy
  publication-title: American Journal of Obstetrics and Gynecology
– volume: 183
  start-page: 1161
  year: 1996
  end-page: 1172
  ident: CR136
  article-title: B lymphocytes secrete antigen-presenting vesicles
  publication-title: Journal of Experimental Medicine
– volume: 38
  start-page: 1359
  year: 2016
  end-page: 1366
  ident: CR64
  article-title: Charge-based precipitation of extracellular vesicles
  publication-title: International Journal of Molecular Medicine
– volume: 5
  start-page: 1
  year: 2015
  end-page: 12
  ident: CR66
  article-title: Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)
  publication-title: Scientific Reports
– volume: 8
  start-page: 1
  year: 2019
  end-page: 36
  ident: CR9
  article-title: Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes
  publication-title: Cells
– volume: 87
  start-page: 46
  year: 2015
  end-page: 58
  ident: CR48
  article-title: Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches
  publication-title: Methods
– volume: 6
  start-page: 1
  year: 2016
  end-page: 10
  ident: CR89
  article-title: Digital detection of exosomes by interferometric imaging
  publication-title: Scientific Reports
– volume: 76
  start-page: 6816
  year: 2016
  end-page: 6827
  ident: CR138
  article-title: The biodistribution and immune suppressive effects of breast cancer–derived exosomes
  publication-title: Cancer Research
– volume: 12
  start-page: 1
  year: 2014
  end-page: 15
  ident: CR35
  article-title: Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation
  publication-title: PLoS Biology
– volume: 131
  start-page: 1
  year: 2018
  end-page: 5
  ident: CR80
  article-title: Sample preparation and imaging of exosomes by transmission electron microscopy
  publication-title: JoVE: Journal of Visualized Experiments
– volume: 31
  start-page: 6577
  year: 2015
  end-page: 6587
  ident: CR79
  article-title: Observations of tunable resistive pulse sensing for exosome analysis: Improving system sensitivity and stability
  publication-title: Langmuir
– volume: 65
  start-page: 391
  year: 2013
  end-page: 397
  ident: CR3
  article-title: Exosomes for targeted siRNA delivery across biological barriers
  publication-title: Advanced Drug Delivery Reviews
– volume: 14
  start-page: 531
  year: 2019
  end-page: 541
  ident: CR117
  article-title: Drug-loaded exosomal preparations from different cell types exhibit distinctive loading capability, yield, and antitumor efficacies: A comparative analysis
  publication-title: International Journal of Nanomedicine
– volume: 380
  start-page: 161
  year: 2004
  end-page: 171
  ident: CR34
  article-title: Mast cell-and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization
  publication-title: Biochemical Journal
– volume: 10
  start-page: 1
  year: 2020
  end-page: 14
  ident: CR110
  article-title: Rigorous characterization of urinary extracellular vesicles (uEVs) in the low centrifugation pellet-a neglected source for uEVs
  publication-title: Scientific Reports
– volume: 77
  start-page: 502
  year: 2010
  end-page: 514
  ident: CR75
  article-title: Flow cytometric analysis of circulating microparticles in plasma
  publication-title: Cytometry Part A
– volume: 22
  start-page: 77
  year: 2000
  end-page: 91
  ident: CR86
  article-title: Surface plasmon resonance-based immunoassays
  publication-title: Methods
– volume: 36
  start-page: 133
  year: 2009
  end-page: 140
  ident: CR147
  article-title: Exosomes derived from IL-12-anchored renal cancer cells increase induction of specific antitumor response in vitro: A novel vaccine for renal cell carcinoma
  publication-title: International Journal of Oncology
– volume: 8
  start-page: 2596
  year: 2010
  end-page: 2607
  ident: CR25
  article-title: Optical and non-optical methods for detection and characterization of microparticles and exosomes
  publication-title: Journal of Thrombosis and Haemostasis
– volume: 17
  start-page: 3558
  year: 2017
  end-page: 3577
  ident: CR49
  article-title: Microfluidics for exosome isolation and analysis: enabling liquid biopsy for personalized medicine
  publication-title: Lab on a Chip
– volume: 6
  start-page: 1
  year: 2016
  end-page: 9
  ident: CR128
  article-title: Real time and label free profiling of clinically relevant exosomes
  publication-title: Scientific Reports
– volume: 7
  start-page: 249
  year: 2018
  end-page: 249
  ident: CR130
  article-title: Co-localization, counting and size characterization of single exosomes using a direct from sample surface capture based imaging technique
  publication-title: Journal of Extracellular Vesicles
– volume: 87
  start-page: 146
  issue: 1
  year: 2011
  end-page: 150
  ident: CR137
  article-title: Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy
  publication-title: Colloids Surf B Biointerfaces
– volume: 1831
  start-page: 1302
  year: 2013
  end-page: 1309
  ident: CR36
  article-title: Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
  publication-title: Biochimica et Biophysica Acta (BBA): Molecular and Cell Biology of Lipids
– volume: 192
  start-page: 170
  year: 2018
  end-page: 187
  ident: CR1
  article-title: Extracellular vesicles and their nucleic acids for biomarker discovery
  publication-title: Pharmacology and Therapeutics
– volume: 90
  start-page: 13663
  year: 2018
  end-page: 13669
  ident: CR120
  article-title: Quantification of micrornas by coupling cyclic enzymatic amplification with microfluidic voltage-assisted liquid desorption electrospray ionization mass spectrometry
  publication-title: Analytical Chemistry
– volume: 5
  start-page: 1
  year: 2016
  end-page: 14
  ident: CR15
  article-title: High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
  publication-title: Journal of Extracellular Vesicles
– volume: 117
  start-page: 39
  year: 2011
  end-page: 48
  ident: CR76
  article-title: Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters
  publication-title: Blood
– volume: 30
  start-page: 1
  year: 2016
  end-page: 8
  ident: CR114
  article-title: Microvesicles preparation from mesenchymal stem cells
  publication-title: Medical Journal of the Islamic Republic of Iran
– volume: 279
  start-page: 447
  year: 2019
  end-page: 457
  ident: CR119
  article-title: Microfluidic exponential rolling circle amplification for sensitive microRNA detection directly from biological samples
  publication-title: Sensors and Actuators B: Chemical
– start-page: 175
  year: 2020
  end-page: 188
  ident: CR44
  article-title: Isolating urinary extracellular vesicles as biomarkers for diabetic disease
  publication-title: Diabetic nephropathy: Methods in molecular biology
– volume: 71
  start-page: 537
  year: 2014
  end-page: 543
  ident: CR148
  article-title: Functions and applications of exosomes
  publication-title: Acta Poloniae Pharmaceutica: Drug Research
– volume: 10
  start-page: 301
  year: 2013
  end-page: 312
  ident: CR135
  article-title: Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
  publication-title: Stem Cell Research
– volume: 6
  start-page: 391
  year: 2015
  end-page: 396
  ident: CR145
  article-title: Small non-coding RNAs transfer through mammalian placenta and directly regulate fetal gene expression
  publication-title: Protein and Cell
– volume: 9
  start-page: 1
  year: 2014
  end-page: 7
  ident: CR68
  article-title: Isolation and characterization of CD34+ blast-derived exosomes in acute myeloid leukemia
  publication-title: PLoS ONE
– volume: 115
  start-page: 10275
  year: 2018
  end-page: 10280
  ident: CR129
  article-title: Interferometric plasmonic imaging and detection of single exosomes
  publication-title: Proceedings of the National Academy of Sciences
– volume: 551
  start-page: 55
  year: 2014
  end-page: 64
  ident: CR40
  article-title: MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal stem cells
  publication-title: Gene
– volume: 15
  start-page: 10481
  year: 2015
  end-page: 10510
  ident: CR123
  article-title: Surface plasmon resonance: A versatile technique for biosensor applications
  publication-title: Sensors
– volume: 6
  start-page: 1
  year: 2016
  end-page: 9
  ident: CR61
  article-title: Size-exclusion chromatography-based isolation minimally alters extracellular vesicles’ characteristics compared to precipitating agents
  publication-title: Scientific Reports
– volume: 49
  start-page: 289
  year: 2001
  end-page: 312
  ident: CR87
  article-title: The use of biosensors for microaffinity purification: An integrated approach to proteomics
  publication-title: Journal of Biochemical and Biophysical Methods
– volume: 7
  start-page: 1
  year: 2018
  end-page: 14
  ident: CR59
  article-title: Efficient ultrafiltration-based protocol to deplete extracellular vesicles from fetal bovine serum
  publication-title: Journal of Extracellular Vesicles
– volume: 2
  start-page: 1
  year: 2019
  end-page: 9
  ident: CR84
  article-title: Extracellular vesicle microRNA quantification from plasma using an integrated microfluidic device
  publication-title: Communications Biology
– volume: 74
  start-page: 613
  year: 2008
  end-page: 621
  ident: CR14
  article-title: Urinary exosomal transcription factors, a new class of biomarkers for renal disease
  publication-title: Kidney International
– volume: 6
  start-page: 1
  year: 2016
  end-page: 14
  ident: CR46
  article-title: ExtraPEG: A polyethylene glycol-based method for enrichment of extracellular vesicles
  publication-title: Scientific Reports
– start-page: 93381K
  year: 2015
  ident: CR105
  article-title: Analysis of bacteria-derived outer membrane vesicles using tunable resistive pulse sensing
  publication-title: Colloidal nanoparticles for biomedical applications X
– volume: 14
  start-page: 1891
  year: 2014
  end-page: 1900
  ident: CR72
  article-title: Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes
  publication-title: Lab on a Chip
– volume: 86
  start-page: 5929
  year: 2014
  end-page: 5936
  ident: CR125
  article-title: Determination of exosome concentration in solution using surface plasmon resonance spectroscopy
  publication-title: Analytical Chemistry
– volume: 16
  start-page: 1423
  year: 2020
  end-page: 1436
  ident: CR77
  article-title: Flow cytometric analysis of extracellular vesicle subsets in plasma: Impact of swarm by particles of non-interest
  publication-title: Journal of Thrombosis and Haemostasis
– volume: 36
  start-page: 2375
  year: 2016
  end-page: 2381
  ident: CR143
  article-title: miR-1246 and miR-4644 in salivary exosome as potential biomarkers for pancreatobiliary tract cancer
  publication-title: Oncology Reports
– volume: 64
  start-page: 1064
  year: 2003
  end-page: 1072
  ident: CR22
  article-title: Exosomes bearing HLA-G are released by melanoma cells
  publication-title: Human Immunology
– volume: 21
  start-page: 194
  year: 2016
  end-page: 200
  ident: CR99
  article-title: Quantitative analysis of exosomes from murine lung cancer cells by flow cytometry
  publication-title: Journal of Cancer Prevention
– volume: 6
  start-page: 1
  year: 2016
  end-page: 13
  ident: CR106
  article-title: Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets
  publication-title: Scientific Reports
– volume: 9
  start-page: 1713526
  issue: 1–19
  year: 2020
  ident: CR100
  article-title: MIFlowCyt-EV: A framework for standardized reporting of extracellular vesicle flow cytometry experiments
  publication-title: Journal of Extracellular Vesicles
– volume: 35
  start-page: 398
  year: 2005
  end-page: 403
  ident: CR18
  article-title: Exosomes contain ubiquitinated proteins
  publication-title: Blood Cells, Molecules, and Diseases
– volume: 110
  start-page: 13
  year: 2008
  end-page: 21
  ident: CR69
  article-title: MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
  publication-title: Gynecologic Oncology
– volume: 147
  start-page: 27
  year: 1991
  end-page: 36
  ident: CR28
  article-title: Exosome formation during maturation of mammalian and avian reticulocytes: Evidence that exosome release is a major route for externalization of obsolete membrane proteins
  publication-title: Journal of Cellular Physiology
– volume: 5
  start-page: 1
  year: 2016
  end-page: 11
  ident: CR62
  article-title: Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer
  publication-title: Journal of Extracellular Vesicles
– volume: 10
  start-page: 452
  year: 2013
  end-page: 455
  ident: CR149
  article-title: Screening of various botanical extracts for antioxidant activity using DPPH free radical method
  publication-title: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
– volume: 16
  start-page: 1
  year: 2014
  end-page: 8
  ident: CR112
  article-title: Dynamic light scattering for the characterization and counting of extracellular vesicles: A powerful noninvasive tool
  publication-title: Journal of Nanoparticle Research
– volume: 97
  start-page: 329
  year: 1983
  end-page: 339
  ident: CR26
  article-title: Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes
  publication-title: The Journal of Cell Biology
– volume: 2
  start-page: 569
  year: 2002
  end-page: 579
  ident: CR29
  article-title: Exosomes: Composition, biogenesis and function
  publication-title: Nature Reviews Immunology
– volume: 33
  start-page: 967
  year: 1983
  end-page: 978
  ident: CR27
  article-title: Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor
  publication-title: Cell
– volume: 8
  start-page: 1
  year: 2020
  end-page: 14
  ident: CR96
  article-title: Analysis of neat biofluids obtained during cardiac surgery using nanoparticle tracking analysis: Methodological considerations
  publication-title: Frontiers in Cell and Developmental Biology
– volume: 114
  start-page: 10584
  year: 2017
  end-page: 10589
  ident: CR71
  article-title: Isolation of exosomes from whole blood by integrating acoustics and microfluidics
  publication-title: Proceedings of the National Academy of Sciences
– volume: 103
  start-page: 738
  year: 2006
  end-page: 743
  ident: CR139
  article-title: Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection
  publication-title: Proceedings of the National Academy of Sciences
– volume: 15
  start-page: 17649
  year: 2015
  end-page: 17665
  ident: CR88
  article-title: Interferometric reflectance imaging sensor (IRIS)–a platform technology for multiplexed diagnostics and digital detection
  publication-title: Sensors
– volume: 30
  start-page: 3
  year: 2006
  end-page: 22
  ident: CR51
  article-title: Isolation and characterization of exosomes from cell culture supernatants and biological fluids
  publication-title: Current Protocols in Cell Biology
– volume: 9
  start-page: 1
  year: 2018
  end-page: 11
  ident: CR52
  article-title: An improvised one-step sucrose cushion ultracentrifugation method for exosome isolation from culture supernatants of mesenchymal stem cells
  publication-title: Stem Cell Research and Therapy
– volume: 185
  start-page: 1
  year: 2018
  end-page: 7
  ident: CR111
  article-title: Comparative proteomics of respiratory exosomes in cystic fibrosis, primary ciliary dyskinesia and asthma
  publication-title: Journal of Proteomics
– volume: 12
  start-page: 1
  year: 2017
  end-page: 8
  ident: CR70
  article-title: Exosome separation using microfluidic systems: Size-based, immunoaffinity-based and dynamic methodologies
  publication-title: Biotechnology Journal
– volume: 9
  start-page: 1
  year: 2014
  end-page: 8
  ident: CR45
  article-title: Ischemic preconditioning potentiates the protective effect of stem cells through secretion of exosomes by targeting Mecp2 via miR-22
  publication-title: PLoS ONE
– start-page: 91
  year: 2017
  end-page: 116
  ident: CR58
  article-title: A protocol for isolation and proteomic characterization of distinct extracellular vesicle subtypes by sequential centrifugal ultrafiltration
  publication-title: Exosomes and Microvesicles
– volume: 10
  start-page: 925
  year: 2009
  end-page: 937
  ident: CR30
  article-title: Multivesicular endosome biogenesis in the absence of ESCRTs
  publication-title: Traffic
– volume: 136
  start-page: 192
  year: 2012
  end-page: 197
  ident: CR92
  article-title: Nanoparticle tracking analysis monitors microvesicle and exosome secretion from immune cells
  publication-title: Immunology
– volume: 11
  start-page: 1
  year: 2016
  end-page: 11
  ident: CR81
  article-title: Comparative analysis of technologies for quantifying extracellular vesicles (EVs) in clinical cerebrospinal fluids (CSF)
  publication-title: PLoS ONE
– volume: 141
  start-page: 1
  year: 2018
  end-page: 9
  ident: CR56
  article-title: Isolation of extracellular vesicles from murine bronchoalveolar lavage fluid using an ultrafiltration centrifugation technique
  publication-title: JoVE: Journal of Visualized Experiments
– volume: 41
  start-page: 48
  year: 2019
  end-page: 54
  ident: CR107
  article-title: Immunotherapy for the treatment of canine transmissible venereal tumor based in dendritic cells pulsed with tumoral exosomes
  publication-title: Immunopharmacology and Immunotoxicology
– volume: 82
  start-page: 1024
  year: 2012
  end-page: 1032
  ident: CR47
  article-title: Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers
  publication-title: Kidney International
– volume: 92
  start-page: 1
  year: 2014
  end-page: 7
  ident: CR102
  article-title: Quantification and size-profiling of extracellular vesicles using tunable resistive pulse sensing
  publication-title: JoVE: Journal of Visualized Experiments
– volume: 7
  start-page: 1
  year: 2018
  end-page: 14
  ident: CR67
  article-title: Immunoaffinity-based isolation of melanoma cell-derived exosomes from plasma of patients with melanoma
  publication-title: Journal of Extracellular Vesicles
– volume: 9
  start-page: 654
  year: 2007
  end-page: 659
  ident: CR41
  article-title: Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
  publication-title: Nature Cell Biology
– volume: 7
  start-page: 3204
  year: 2015
  end-page: 3225
  ident: CR55
  article-title: Exosomes and their role in the life cycle and pathogenesis of RNA viruses
  publication-title: Viruses
– volume: 141
  start-page: 4640
  year: 2016
  end-page: 4646
  ident: CR65
  article-title: Effective isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling
  publication-title: Analyst
– volume: 86
  start-page: 8857
  year: 2014
  end-page: 8864
  ident: CR127
  article-title: Label-free quantitative detection of tumor-derived exosomes through surface plasmon resonance imaging
  publication-title: Analytical Chemistry
– volume: 24
  start-page: 385
  year: 2013
  end-page: 392
  ident: CR131
  article-title: TGF-β1–containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis
  publication-title: Journal of the American Society of Nephrology
– volume: 9
  start-page: 1
  year: 2014
  ident: 300_CR45
  publication-title: PLoS ONE
– volume: 6
  start-page: 1
  year: 2006
  ident: 300_CR16
  publication-title: BMC Cancer
  doi: 10.1186/1471-2407-6-283
– volume: 10
  start-page: 964
  year: 2019
  ident: 300_CR4
  publication-title: ACS Chemical Neuroscience
  doi: 10.1021/acschemneuro.8b00469
– volume: 273
  start-page: 20121
  year: 1998
  ident: 300_CR11
  publication-title: Journal of Biological Chemistry
  doi: 10.1074/jbc.273.32.20121
– volume: 6
  start-page: 1
  year: 2016
  ident: 300_CR61
  publication-title: Scientific Reports
  doi: 10.1038/srep33641
– volume: 11
  start-page: 230
  year: 2012
  ident: 300_CR6
  publication-title: Molecular and Cellular Proteomics
  doi: 10.1074/mcp.M111.012732
– start-page: 175
  volume-title: Diabetic nephropathy: Methods in molecular biology
  year: 2020
  ident: 300_CR44
  doi: 10.1007/978-1-4939-9841-8_13
– volume: 7
  start-page: 789
  year: 2017
  ident: 300_CR33
  publication-title: Theranostics
  doi: 10.7150/thno.18133
– volume: 8
  start-page: 1
  year: 2017
  ident: 300_CR133
  publication-title: Nature Communications
  doi: 10.1038/s41467-016-0009-6
– volume: 14
  start-page: 531
  year: 2019
  ident: 300_CR117
  publication-title: International Journal of Nanomedicine
  doi: 10.2147/IJN.S191313
– volume: 40
  start-page: 10937
  year: 2012
  ident: 300_CR39
  publication-title: Nucleic Acids Research
  doi: 10.1093/nar/gks832
– start-page: 91
  volume-title: Exosomes and Microvesicles
  year: 2017
  ident: 300_CR58
  doi: 10.1007/978-1-4939-6728-5_7
– volume: 1831
  start-page: 1302
  year: 2013
  ident: 300_CR36
  publication-title: Biochimica et Biophysica Acta (BBA): Molecular and Cell Biology of Lipids
  doi: 10.1016/j.bbalip.2013.04.011
– volume: 103
  start-page: 738
  year: 2006
  ident: 300_CR139
  publication-title: Proceedings of the National Academy of Sciences
  doi: 10.1073/pnas.0507995103
– volume: 12
  start-page: 1
  year: 2014
  ident: 300_CR35
  publication-title: PLoS Biology
  doi: 10.1371/journal.pbio.1001874
– volume: 141
  start-page: 1
  year: 2018
  ident: 300_CR56
  publication-title: JoVE: Journal of Visualized Experiments
– volume: 22
  start-page: 113
  year: 2018
  ident: 300_CR146
  publication-title: The Korean Journal of Physiology and Pharmacology
  doi: 10.4196/kjpp.2018.22.2.113
– volume: 54
  start-page: 53
  year: 2014
  ident: 300_CR31
  publication-title: Progress in Lipid Research
  doi: 10.1016/j.plipres.2014.01.004
– volume: 6
  start-page: 391
  year: 2015
  ident: 300_CR145
  publication-title: Protein and Cell
  doi: 10.1007/s13238-015-0156-2
– volume: 23
  start-page: 865
  year: 2018
  ident: 300_CR63
  publication-title: Frontiers in Bioscience
  doi: 10.2741/4621
– volume: 35
  start-page: 398
  year: 2005
  ident: 300_CR18
  publication-title: Blood Cells, Molecules, and Diseases
  doi: 10.1016/j.bcmd.2005.08.005
– volume: 168
  start-page: 134
  year: 2018
  ident: 300_CR116
  publication-title: Colloids and Surfaces B: Biointerfaces
  doi: 10.1016/j.colsurfb.2018.02.006
– volume: 122
  start-page: 2163
  issue: 13
  year: 2009
  ident: 300_CR23
  publication-title: Journal of cell science
  doi: 10.1242/jcs.029884
– volume: 87
  start-page: 46
  year: 2015
  ident: 300_CR48
  publication-title: Methods
  doi: 10.1016/j.ymeth.2015.05.028
– volume: 9
  start-page: 1
  year: 2019
  ident: 300_CR90
  publication-title: Scientific Reports
  doi: 10.1038/s41598-018-37186-2
– volume: 9
  start-page: 1
  year: 2018
  ident: 300_CR52
  publication-title: Stem Cell Research and Therapy
  doi: 10.1186/s13287-018-0923-0
– volume: 16
  start-page: 1
  year: 2014
  ident: 300_CR112
  publication-title: Journal of Nanoparticle Research
  doi: 10.1007/s11051-014-2583-z
– volume: 17
  start-page: 3558
  year: 2017
  ident: 300_CR49
  publication-title: Lab on a Chip
  doi: 10.1039/C7LC00592J
– volume: 9
  start-page: 1713526
  issue: 1–19
  year: 2020
  ident: 300_CR100
  publication-title: Journal of Extracellular Vesicles
  doi: 10.1080/20013078.2020.1713526
– volume: 64
  start-page: 1064
  year: 2003
  ident: 300_CR22
  publication-title: Human Immunology
  doi: 10.1016/j.humimm.2003.08.344
– volume: 380
  start-page: 161
  year: 2004
  ident: 300_CR34
  publication-title: Biochemical Journal
  doi: 10.1042/bj20031594
– volume: 183
  start-page: 1161
  year: 1996
  ident: 300_CR136
  publication-title: Journal of Experimental Medicine
  doi: 10.1084/jem.183.3.1161
– volume: 9
  start-page: 654
  year: 2007
  ident: 300_CR41
  publication-title: Nature Cell Biology
  doi: 10.1038/ncb1596
– volume: 31
  start-page: 114
  year: 2004
  ident: 300_CR24
  publication-title: American Journal of Respiratory Cell and Molecular Biology
  doi: 10.1165/rcmb.2003-0238OC
– volume: 17
  start-page: 3599
  issue: 10
  year: 2018
  ident: 300_CR43
  publication-title: Journal of Proteome Research
  doi: 10.1021/acs.jproteome.8b00479
– volume: 92
  start-page: 1
  year: 2014
  ident: 300_CR102
  publication-title: JoVE: Journal of Visualized Experiments
– volume: 11
  start-page: 1
  year: 2016
  ident: 300_CR81
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0149866
– volume: 15
  start-page: 17649
  year: 2015
  ident: 300_CR88
  publication-title: Sensors
  doi: 10.3390/s150717649
– volume: 247
  start-page: 163
  year: 2001
  ident: 300_CR19
  publication-title: Journal of Immunological Methods
  doi: 10.1016/S0022-1759(00)00321-5
– volume: 147
  start-page: 27
  year: 1991
  ident: 300_CR28
  publication-title: Journal of Cellular Physiology
  doi: 10.1002/jcp.1041470105
– volume: 192
  start-page: 170
  year: 2018
  ident: 300_CR1
  publication-title: Pharmacology and Therapeutics
  doi: 10.1016/j.pharmthera.2018.08.002
– volume: 33
  start-page: 967
  year: 1983
  ident: 300_CR27
  publication-title: Cell
  doi: 10.1016/0092-8674(83)90040-5
– volume: 10
  start-page: 925
  year: 2009
  ident: 300_CR30
  publication-title: Traffic
  doi: 10.1111/j.1600-0854.2009.00920.x
– volume: 136
  start-page: 192
  year: 2012
  ident: 300_CR92
  publication-title: Immunology
  doi: 10.1111/j.1365-2567.2012.03569.x
– volume: 166
  start-page: 7309
  year: 2001
  ident: 300_CR7
  publication-title: The Journal of Immunology
  doi: 10.4049/jimmunol.166.12.7309
– volume: 5
  start-page: 1
  year: 2016
  ident: 300_CR54
  publication-title: Journal of Extracellular Vesicles
  doi: 10.3402/jev.v5.30829
– volume: 24
  start-page: 385
  year: 2013
  ident: 300_CR131
  publication-title: Journal of the American Society of Nephrology
  doi: 10.1681/ASN.2012101031
– volume: 4
  start-page: 1
  year: 2009
  ident: 300_CR85
  publication-title: PLoS ONE
  doi: 10.1371/annotation/c9e68857-cd7e-4b1c-9765-04f66d8237d0
– volume: 7
  start-page: 1
  year: 2018
  ident: 300_CR59
  publication-title: Journal of Extracellular Vesicles
  doi: 10.1080/20013078.2017.1422674
– volume: 4
  start-page: 1
  year: 2015
  ident: 300_CR101
  publication-title: Journal of Extracellular Vesicles
  doi: 10.3402/jev.v4.25530
– volume: 7
  start-page: 249
  year: 2018
  ident: 300_CR130
  publication-title: Journal of Extracellular Vesicles
– volume: 8
  start-page: 1
  year: 2019
  ident: 300_CR9
  publication-title: Cells
– volume: 87
  start-page: 146
  issue: 1
  year: 2011
  ident: 300_CR137
  publication-title: Colloids Surf B Biointerfaces
  doi: 10.1016/j.colsurfb.2011.05.013
– volume: 16
  start-page: 1
  year: 2020
  ident: 300_CR50
  publication-title: Small (Weinheim an der Bergstrasse, Germany)
– volume: 10
  start-page: 452
  year: 2013
  ident: 300_CR149
  publication-title: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
  doi: 10.4314/ajtcam.v10i6.9
– volume: 141
  start-page: 4640
  year: 2016
  ident: 300_CR65
  publication-title: Analyst
  doi: 10.1039/C6AN00892E
– volume: 30
  start-page: 3
  year: 2006
  ident: 300_CR51
  publication-title: Current Protocols in Cell Biology
  doi: 10.1002/0471143030.cb0322s30
– volume: 10
  start-page: 559
  year: 2018
  ident: 300_CR124
  publication-title: Bioanalysis
  doi: 10.4155/bio-2017-0271
– volume: 15
  start-page: 10481
  year: 2015
  ident: 300_CR123
  publication-title: Sensors
  doi: 10.3390/s150510481
– volume: 110
  start-page: 13
  year: 2008
  ident: 300_CR69
  publication-title: Gynecologic Oncology
  doi: 10.1016/j.ygyno.2008.04.033
– year: 2020
  ident: 300_CR98
  publication-title: Cytometry Part A
  doi: 10.1002/cyto.a.24193
– volume: 86
  start-page: 5929
  year: 2014
  ident: 300_CR125
  publication-title: Analytical Chemistry
  doi: 10.1021/ac500931f
– volume: 38
  start-page: 1359
  year: 2016
  ident: 300_CR64
  publication-title: International Journal of Molecular Medicine
  doi: 10.3892/ijmm.2016.2759
– volume: 8
  start-page: 1701
  year: 2014
  ident: 300_CR53
  publication-title: Oncology Letters
  doi: 10.3892/ol.2014.2373
– volume: 5
  start-page: 1
  year: 2015
  ident: 300_CR66
  publication-title: Scientific Reports
  doi: 10.1038/srep14664
– volume: 126
  start-page: 1208
  year: 2016
  ident: 300_CR20
  publication-title: The Journal of Clinical Investigation
  doi: 10.1172/JCI81135
– volume: 30
  start-page: 1
  year: 2016
  ident: 300_CR114
  publication-title: Medical Journal of the Islamic Republic of Iran
– volume: 319
  start-page: 1706
  year: 2013
  ident: 300_CR95
  publication-title: Experimental Cell Research
  doi: 10.1016/j.yexcr.2012.10.006
– volume: 102
  start-page: 4336
  year: 2003
  ident: 300_CR12
  publication-title: Blood
  doi: 10.1182/blood-2003-03-0871
– volume: 29
  start-page: 1784
  year: 2018
  ident: 300_CR93
  publication-title: Journal of the American Society of Nephrology
  doi: 10.1681/ASN.2018020115
– volume: 17
  start-page: 1
  year: 2016
  ident: 300_CR8
  publication-title: International Journal of Molecular Sciences
  doi: 10.3390/ijms17020170
– volume: 65
  start-page: 391
  year: 2013
  ident: 300_CR3
  publication-title: Advanced Drug Delivery Reviews
  doi: 10.1016/j.addr.2012.08.008
– volume: 90
  start-page: 13663
  year: 2018
  ident: 300_CR120
  publication-title: Analytical Chemistry
  doi: 10.1021/acs.analchem.8b04008
– volume: 135
  start-page: 129
  year: 2019
  ident: 300_CR126
  publication-title: Biosensors and Bioelectronics
  doi: 10.1016/j.bios.2019.04.013
– volume: 2
  start-page: 569
  year: 2002
  ident: 300_CR29
  publication-title: Nature Reviews Immunology
  doi: 10.1038/nri855
– volume: 36
  start-page: 2375
  year: 2016
  ident: 300_CR143
  publication-title: Oncology Reports
  doi: 10.3892/or.2016.5021
– volume: 169
  start-page: 1
  year: 2020
  ident: 300_CR122
  publication-title: Biosensors and Bioelectronics
  doi: 10.1016/j.bios.2020.112622
– volume: 86
  start-page: 8857
  year: 2014
  ident: 300_CR127
  publication-title: Analytical Chemistry
  doi: 10.1021/ac5023056
– volume: 22
  start-page: 77
  year: 2000
  ident: 300_CR86
  publication-title: Methods
  doi: 10.1006/meth.2000.1039
– volume: 7
  start-page: 1
  year: 2018
  ident: 300_CR67
  publication-title: Journal of Extracellular Vesicles
  doi: 10.1080/20013078.2018.1435138
– volume: 8
  start-page: 1
  year: 2020
  ident: 300_CR96
  publication-title: Frontiers in Cell and Developmental Biology
  doi: 10.3389/fcell.2020.00367
– volume: 12
  start-page: 1
  year: 2017
  ident: 300_CR70
  publication-title: Biotechnology Journal
  doi: 10.1002/biot.201600699
– volume: 27
  start-page: 796
  year: 2010
  ident: 300_CR91
  publication-title: Pharmaceutical Research
  doi: 10.1007/s11095-010-0073-2
– volume: 10
  start-page: 301
  year: 2013
  ident: 300_CR135
  publication-title: Stem Cell Research
  doi: 10.1016/j.scr.2013.01.002
– volume: 1660
  start-page: 355
  year: 2017
  ident: 300_CR83
  publication-title: Methods in Molecular Biology
  doi: 10.1007/978-1-4939-7253-1_29
– volume: 185
  start-page: 1
  year: 2018
  ident: 300_CR111
  publication-title: Journal of Proteomics
  doi: 10.1016/j.jprot.2018.07.001
– volume: 31
  start-page: 6577
  year: 2015
  ident: 300_CR79
  publication-title: Langmuir
  doi: 10.1021/acs.langmuir.5b01402
– volume: 147
  start-page: 599
  year: 1999
  ident: 300_CR17
  publication-title: The Journal of Cell Biology
  doi: 10.1083/jcb.147.3.599
– volume: 41
  start-page: 1
  year: 2020
  ident: 300_CR121
  publication-title: Electrophoresis
– volume: 117
  start-page: 39
  year: 2011
  ident: 300_CR76
  publication-title: Blood
  doi: 10.1182/blood-2010-09-307595
– volume: 6
  start-page: 1
  year: 2016
  ident: 300_CR46
  publication-title: Scientific Reports
  doi: 10.1038/srep23978
– volume: 131
  start-page: 1
  year: 2018
  ident: 300_CR80
  publication-title: JoVE: Journal of Visualized Experiments
– start-page: 93381K
  volume-title: Colloidal nanoparticles for biomedical applications X
  year: 2015
  ident: 300_CR105
– volume: 79
  start-page: 1767
  year: 2019
  ident: 300_CR113
  publication-title: The Prostate
  doi: 10.1002/pros.23901
– volume: 26
  start-page: 4215
  year: 2007
  ident: 300_CR37
  publication-title: The EMBO Journal
  doi: 10.1038/sj.emboj.7601850
– volume: 6
  start-page: 1
  year: 2016
  ident: 300_CR89
  publication-title: Scientific Reports
  doi: 10.1038/srep37246
– volume: 14
  start-page: 1891
  year: 2014
  ident: 300_CR72
  publication-title: Lab on a Chip
  doi: 10.1039/C4LC00136B
– volume: 20
  start-page: 847
  year: 2006
  ident: 300_CR144
  publication-title: Leukemia
  doi: 10.1038/sj.leu.2404132
– volume: 82
  start-page: 1024
  year: 2012
  ident: 300_CR47
  publication-title: Kidney International
  doi: 10.1038/ki.2012.256
– volume: 7
  start-page: 780
  year: 2011
  ident: 300_CR73
  publication-title: Nanomedicine: Nanotechnology, Biology and Medicine
  doi: 10.1016/j.nano.2011.04.003
– volume: 12
  start-page: 1
  year: 2017
  ident: 300_CR118
  publication-title: PLoS ONE
– volume: 94
  start-page: 3791
  year: 1999
  ident: 300_CR5
  publication-title: Blood
  doi: 10.1182/blood.V94.11.3791
– volume: 3
  start-page: 1
  year: 2014
  ident: 300_CR60
  publication-title: Journal of Extracellular Vesicles
  doi: 10.3402/jev.v3.23430
– volume: 200
  start-page: 87
  year: 2015
  ident: 300_CR74
  publication-title: Journal of Controlled Release
  doi: 10.1016/j.jconrel.2014.12.041
– volume: 16
  start-page: 1423
  year: 2020
  ident: 300_CR77
  publication-title: Journal of Thrombosis and Haemostasis
  doi: 10.1111/jth.14154
– volume: 14
  start-page: 1
  year: 2018
  ident: 300_CR94
  publication-title: BMC Veterinary Research
  doi: 10.1186/s12917-018-1509-x
– volume: 551
  start-page: 55
  year: 2014
  ident: 300_CR40
  publication-title: Gene
  doi: 10.1016/j.gene.2014.08.041
– volume: 6
  start-page: 1
  year: 2016
  ident: 300_CR128
  publication-title: Scientific Reports
  doi: 10.1038/s41598-016-0001-8
– volume: 2
  start-page: 1
  year: 2019
  ident: 300_CR84
  publication-title: Communications Biology
  doi: 10.1038/s42003-019-0435-1
– volume: 77
  start-page: 502
  year: 2010
  ident: 300_CR75
  publication-title: Cytometry Part A
  doi: 10.1002/cyto.a.20886
– volume: 292
  start-page: 1657
  year: 2007
  ident: 300_CR57
  publication-title: American Journal of Physiology-Renal Physiology
  doi: 10.1152/ajprenal.00434.2006
– volume: 41
  start-page: 48
  year: 2019
  ident: 300_CR107
  publication-title: Immunopharmacology and Immunotoxicology
  doi: 10.1080/08923973.2018.1533969
– volume: 279
  start-page: 447
  year: 2019
  ident: 300_CR119
  publication-title: Sensors and Actuators B: Chemical
  doi: 10.1016/j.snb.2018.09.121
– volume: 5
  start-page: 1
  year: 2016
  ident: 300_CR15
  publication-title: Journal of Extracellular Vesicles
  doi: 10.3402/jev.v5.32570
– start-page: 163
  volume-title: Progressinmolecularbiologyandtranslationalscience
  year: 2017
  ident: 300_CR142
– volume: 114
  start-page: 10584
  year: 2017
  ident: 300_CR71
  publication-title: Proceedings of the National Academy of Sciences
  doi: 10.1073/pnas.1709210114
– volume: 115
  start-page: 10275
  year: 2018
  ident: 300_CR129
  publication-title: Proceedings of the National Academy of Sciences
  doi: 10.1073/pnas.1804548115
– volume: 5
  start-page: 1
  year: 2016
  ident: 300_CR104
  publication-title: Journal of Extracellular Vesicles
  doi: 10.3402/jev.v5.31242
– volume: 10
  start-page: 1
  year: 2020
  ident: 300_CR110
  publication-title: Scientific Reports
  doi: 10.1038/s41598-020-60619-w
– volume: 74
  start-page: 613
  year: 2008
  ident: 300_CR14
  publication-title: Kidney International
  doi: 10.1038/ki.2008.206
– start-page: 21
  volume-title: Exosomes and microvesicles
  year: 2017
  ident: 300_CR78
  doi: 10.1007/978-1-4939-6728-5_2
– volume: 56
  start-page: 293
  year: 2012
  ident: 300_CR21
  publication-title: Methods
  doi: 10.1016/j.ymeth.2012.01.002
– volume: 5
  start-page: 1
  year: 2016
  ident: 300_CR62
  publication-title: Journal of Extracellular Vesicles
– volume: 9
  start-page: 1
  year: 2019
  ident: 300_CR109
  publication-title: Animals
  doi: 10.3390/ani9100717
– volume: 117
  start-page: 1
  year: 2010
  ident: 300_CR38
  publication-title: Journal of Neural Transmission
  doi: 10.1007/s00702-009-0288-8
– volume: 9
  start-page: 1
  year: 2014
  ident: 300_CR68
  publication-title: PLoS ONE
– volume: 21
  start-page: 194
  year: 2016
  ident: 300_CR99
  publication-title: Journal of Cancer Prevention
  doi: 10.15430/JCP.2016.21.3.194
– volume: 6
  start-page: 1
  year: 2016
  ident: 300_CR106
  publication-title: Scientific Reports
  doi: 10.1038/s41598-016-0001-8
– volume: 40
  start-page: 457
  year: 2017
  ident: 300_CR115
  publication-title: Cellular Oncology
  doi: 10.1007/s13402-017-0335-7
– volume: 14
  start-page: 4281
  year: 2009
  ident: 300_CR134
  publication-title: Frontiers in Bioscience (Landmark Edition)
  doi: 10.2741/3528
– volume: 49
  start-page: 289
  year: 2001
  ident: 300_CR87
  publication-title: Journal of Biochemical and Biophysical Methods
  doi: 10.1016/S0165-022X(01)00205-6
– volume: 71
  start-page: 537
  year: 2014
  ident: 300_CR148
  publication-title: Acta Poloniae Pharmaceutica: Drug Research
– volume: 36
  start-page: 133
  year: 2009
  ident: 300_CR147
  publication-title: International Journal of Oncology
– volume: 291
  start-page: 25462
  year: 2016
  ident: 300_CR13
  publication-title: Journal of Biological Chemistry
  doi: 10.1074/jbc.M116.729202
– volume: 88
  start-page: 851
  year: 2010
  ident: 300_CR10
  publication-title: Immunology and Cell Biology
  doi: 10.1038/icb.2010.64
– volume: 2
  start-page: 1
  year: 2011
  ident: 300_CR42
  publication-title: Nature Communications
  doi: 10.1038/ncomms1285
– volume: 8
  start-page: 2596
  year: 2010
  ident: 300_CR25
  publication-title: Journal of Thrombosis and Haemostasis
  doi: 10.1111/j.1538-7836.2010.04074.x
– volume: 7
  start-page: 3204
  year: 2015
  ident: 300_CR55
  publication-title: Viruses
  doi: 10.3390/v7062770
– volume: 54
  start-page: 76
  year: 2017
  ident: 300_CR141
  publication-title: Placenta
  doi: 10.1016/j.placenta.2016.12.002
– volume: 2
  start-page: 123
  year: 2000
  ident: 300_CR82
  publication-title: Journal of Nanoparticle Research
  doi: 10.1023/A:1010067107182
– volume-title: Biological function of exosomes as diagnostic markers and therapeutic delivery vehicles in carcinogenesis and infectious diseases
  year: 2018
  ident: 300_CR2
– volume: 7
  start-page: 1
  year: 2020
  ident: 300_CR108
  publication-title: Frontiers in Nutrition
  doi: 10.3389/fnut.2020.00022
– volume: 315
  start-page: 1584
  year: 2009
  ident: 300_CR32
  publication-title: Experimental Cell Research
  doi: 10.1016/j.yexcr.2008.09.020
– ident: 300_CR97
  doi: 10.1016/bs.mie.2020.06.011
– volume: 142
  start-page: 4093
  year: 2020
  ident: 300_CR103
  publication-title: Journal of the American Chemical Society
  doi: 10.1021/jacs.9b13221
– volume: 213
  start-page: 173
  year: 2015
  ident: 300_CR132
  publication-title: American Journal of Obstetrics and Gynecology
  doi: 10.1016/j.ajog.2015.07.001
– volume: 97
  start-page: 329
  year: 1983
  ident: 300_CR26
  publication-title: The Journal of Cell Biology
  doi: 10.1083/jcb.97.2.329
– volume: 12
  start-page: 1
  year: 2014
  ident: 300_CR140
  publication-title: Journal of Translational Medicine
  doi: 10.1186/1479-5876-12-204
– volume: 76
  start-page: 6816
  year: 2016
  ident: 300_CR138
  publication-title: Cancer Research
  doi: 10.1158/0008-5472.CAN-16-0868
SSID ssj0021543
Score 2.6047747
SecondaryResourceType review_article
Snippet Exosomes are the smallest extracellular vesicles present in most of the biological fluids. They are found to play an important role in cell signaling, immune...
SourceID pubmedcentral
proquest
pubmed
crossref
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 249
SubjectTerms Biochemistry
Biological Techniques
Biomarkers
Biosynthesis
Biotechnology
Cell Biology
Chemistry
Chemistry and Materials Science
Communication
Electron microscopy
Exosomes
Extracellular vesicles
Flow cytometry
gel chromatography
Higher education
Human Genetics
Immune response
Immune system
Life sciences
Light scattering
Lipids
Metastases
Metastasis
Microfluidic devices
Microfluidics
Microscopy
Nanoparticles
neoplasms
Photon correlation spectroscopy
Plasma
Protein Science
Proteins
Review
Size exclusion chromatography
therapeutics
Ultracentrifugation
Ultrafiltration
Vesicles
SummonAdditionalLinks – databaseName: Biological Science Database
  dbid: M7P
  link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3fb9QwDLbGAIk9wBi_CmMKEm8QrW2aa8MLmqabAIlpSCDtrUqTdDtptGO9Q9t_Pzvp9Tim3cveqjaVYtlxPsfOZ4D3NaIMi9ssl3XseGZVxbWuRzxPlNRiVMlaad9sIj88LI6P1VF_4Nb1ZZVzn-gdtW0NnZHvYphQ5EQ1k34-_8OpaxRlV_sWGvfgPrEkCF-6dzQEXAgPQoF9LvgIsUV_aSZcnUupixkVKJCdoy9a3phuoM2bRZP_ZU79hnTw5K6ibMLjHoqyvWA7T2HNNVvwMDSnvNqCjX-oCp_Bt_HZzEzoLkRzwr77ttMdQ8DLvqLxeu0y3Vj2Y6ZD9VF41dZsfNl27W_XfWJ7LCQinsOvg_HP_S-878PADaLFKbcm1bbQurIofYohlvWPOlUyrqraGJVLZ6wUsbOIPi2CkNzGGrGldEmlnHgB603buFfAVFJlmcUQSsk0c7VTmRGjpDCqSETlUh1BMldCaXqScuqVcVYu6JVJcSUqrvSKK0UEH4Z_zgNFx8rR23OllP1y7cqFRiJ4N3zGhUbZE924dkZjiLdZIP5dMUbSPWAUL4vgZTCXYUqCeCARPEWQLxnSMICIvpe_NJNTT_iNPjNGtBHBx7nJLaZ-u6SvV0v6Bh6l3vypCmkb1qcXM_cWHpi_00l3seMX0jXPWCN-
  priority: 102
  providerName: ProQuest
Title Elucidating Methods for Isolation and Quantification of Exosomes: A Review
URI https://link.springer.com/article/10.1007/s12033-021-00300-3
https://www.ncbi.nlm.nih.gov/pubmed/33492613
https://www.proquest.com/docview/2498797212
https://www.proquest.com/docview/2480753656
https://www.proquest.com/docview/2551976054
https://pubmed.ncbi.nlm.nih.gov/PMC7940341
Volume 63
WOSCitedRecordID wos000611412100001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAVX
  databaseName: SpringerLink Journals
  customDbUrl:
  eissn: 1559-0305
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0021543
  issn: 1073-6085
  databaseCode: RSV
  dateStart: 19970101
  isFulltext: true
  titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22
  providerName: Springer Nature
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED-xDQR74KODkTEqI_EGkZI4ruO9bVMnQFpVNkB9ixzbgUojmZYWwX_P2U5SymASvFj5uET-OPt-lu9-B_CyRJSh0cyGrIxMmGpRhFKWo5DHgkk6KlgppEs2wSeTbDYT0zYorOm83bsjSbdSr4LdEpt3zLoUWM3E1WMDttDcZXY6np1_6rdZCAq8Wz2n4QgRRRsq8-d_rJujaxjzuqvkb-elzgydPPi_BjyE-y3sJIdeTx7BLVMN4I5PRPljAHePu7xvA9j-haJwB96NL5ZqbmMgqs_k1KWbbggCXfIWldaNKpGVJu-X0nsd-Ud1Scbf66b-apoDckj8AcRj-Hgy_nD8JmzzL4QKUeIi1CqROpOy0Nj-BLdW2l3KRLCoKEqlBGdGaUYjoxF1agQfXEcSMSUzcSEMfQKbVV2Zp0BEXKSpxq2TYElqSiNSRUdxpnD0aGESGUDcDUOuWnJymyPjIl_RKtvey7H3ctd7OQ3gVf_NpafmuFF6vxvdvJ2mTY57z4xb_qIkgBf9a-xve2oiK1MvrYzla6aIe2-QYTb-F5uXBrDrFaavErX8jwiaAuBrqtQLWILv9TfV_Isj-sa1MkKUEcDrTqFWVf97S_f-TfwZ3EucTlpvpH3YXFwtzXO4rb4t5s3VEDb4jLsyG8LW0XgyPcO702RqS-7L86GbgD8BxAojKg
linkProvider Springer Nature
linkToHtml http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VAgIOPMorUMBIcIKIxI43MRJCFWzVpe2qSK3UW3BsB1YqSWl2gf4pfiNjO8myVOytB25R4o0ym29mvonnAfCsRJah0c2GvIxMmGhRhFKWgzCNBZdsUPBSSDdsIh2Ps8NDsbcCv7paGJtW2dlEZ6h1rew38lcYJmSpbTVD3x5_C-3UKLu72o3Q8LDYNqc_MGRr3oze4_t9TunmcP_dVthOFQgVcp9pqBWVOpOy0AYPMWDQ7lBSwaOiKJUSKTdKcxYZjVxKo0tNdSSRKXETF8IwvO8FuIjy0cylCu71AR7SEZ_Qn7JwgFymLdLxpXrUTk2zCRFWr9D2LTrCM-z2bJLmXzu1zgFu3vjf_rqbcL2l2mTD68YtWDHVGlz2wzdP1-DaH60Yb8OH4dFMTWytR_WZ7Lqx2g1BQk9GqJwOvURWmnycSZ9d5U_VJRn-rJv6q2lekw3iN1ruwMG5iHUXVqu6MveBiLhIEo0houA0MaURiWKDOFMii1lhqAwg7l56rtom7HYWyFE-bx9tgZIjUHIHlJwF8KL_zbFvQbJ09XoHgrw1R00-R0AAT_vLaEjs7pCsTD2za2xfaob8fskabuucUbwkgHsenv0jMdvnEslhAOkCcPsFtpH54pVq8sU1NEefECGbCuBlB_H5o_9b0gfLJX0CV7b2d3fyndF4-yFcpU71bMbVOqxOT2bmEVxS36eT5uSxU2ICn84b-r8BoyiFbQ
linkToPdf http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Nb9NAEB2VAlU58FFKMRRYJDiBVX_GXiSEKpqIUIiCRKXezHp3DZGKXeqEtn-NX8fMru0QKnLrgZsVbyJv8mbmTXbmDcCzAlmGwjDrxoWn3Ujx3BWi6LmJz2MR9vK44MIMm0hGo_TwkI9X4FfbC0Nlla1PNI5aVZL-I9_BNCFNSGom2Cmasojx3uDN8Q-XJkjRSWs7TsNCZF-fn2L6Vr8e7uFv_TwIBv3Pb9-5zYQBVyIPmrpKBkKlQuRK4yUmD8pcioDHXp4XUvIk1lLFoacV8iqF4TVRnkDWFGs_5zrEz70CVxMSLTdlg-Mu2UNqYov7k9DtIa9pGnZs215AE9SoOIJsDP3gYlC8wHQvFmz-dWprguHg1v_8Nd6Gmw0FZ7vWZu7Aii434Lodynm-ATf-kGi8C-_7RzM5oR6Q8iv7aMZt1wyJPhui0RpUM1Eq9mkmbNWVfakqWP-sqqvvun7Fdpk9gNmEg0vZ1j1YLatS3wfG_TyKFKaOPA4iXWgeybDnp5KnfpjrQDjgtwDIZCPOTjNCjrK5rDSBJkPQZAY0WejAi-49x1aaZOnq7RYQWeOm6myOBgeedrfRwdCpkSh1NaM1pFcdIu9fsiam_mfcXuTAloVq90gh6V8iaXQgWQBxt4AEzhfvlJNvRugcY4WHLMuBly3c54_-750-WL7TJ7CGiM8-DEf7D2E9MFZIhVjbsDo9melHcE3-nE7qk8fGnhl8uWzk_wacFY4q
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Elucidating+Methods+for+Isolation+and+Quantification+of+Exosomes%3A+A+Review&rft.jtitle=Molecular+biotechnology&rft.au=Kurian%2C+Talitha+Keren&rft.au=Banik%2C+Soumyabrata&rft.au=Gopal%2C+Dharshini&rft.au=Chakrabarti%2C+Shweta&rft.date=2021-04-01&rft.issn=1559-0305&rft.eissn=1559-0305&rft.volume=63&rft.issue=4&rft.spage=249&rft_id=info:doi/10.1007%2Fs12033-021-00300-3&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1073-6085&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1073-6085&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1073-6085&client=summon