Increased immune cell infiltration of the exocrine pancreas: a possible contribution to the pathogenesis of type 1 diabetes

Type 1 diabetes (T1D) results from a complex interplay between genetic susceptibility and environmental factors that have been implicated in the pathogenesis of disease both as triggers and potentiators of β-cell destruction. CD8 T cells are the main cell type found in human islets, and they have be...

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Bibliographic Details
Published in:	Diabetes (New York, N.Y.) Vol. 63; no. 11; p. 3880
Main Authors:	Rodriguez-Calvo, Teresa, Ekwall, Olov, Amirian, Natalie, Zapardiel-Gonzalo, Jose, von Herrath, Matthias G
Format:	Journal Article
Language:	English
Published:	United States 01.11.2014
Subjects:	Adult CD4-Positive T-Lymphocytes - metabolism CD8-Positive T-Lymphocytes - metabolism Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - metabolism Diabetes Mellitus, Type 1 - pathology Female Fluorescent Antibody Technique Humans In Vitro Techniques Islets of Langerhans - immunology Islets of Langerhans - metabolism Islets of Langerhans - pathology Male Pancreas, Exocrine - cytology Pancreas, Exocrine - immunology Pancreas, Exocrine - metabolism
ISSN:	1939-327X, 1939-327X
Online Access:	Get more information
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