Zoonosis: An Emerging Link to Antibiotic Resistance Under “One Health Approach”

Current scenario in communicable diseases has generated new era that identifies the “One health” approach to understand the sharing and management of etiological agents with its impact on ecosystem. Under this context the relevance of zoonotic diseases generates major concern. The indiscriminate and...

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Bibliographic Details
Published in:Indian journal of microbiology Vol. 60; no. 2; pp. 139 - 152
Main Authors: Dafale, Nishant A., Srivastava, Shweta, Purohit, Hemant J.
Format: Journal Article
Language:English
Published: New Delhi Springer India 01.06.2020
Springer Nature B.V
Subjects:
Animal husbandry
Anthrax
Antibiotic resistance
Antibiotics
Bacillus anthracis
Bioaccumulation
Biodegradation
Biomedical and Life Sciences
Bioreactors
bovine tuberculosis
breeding
Brucella melitensis biovar Abortus
Brucellosis
Colitis
control methods
Digestive system
Disease transmission
Drug resistance
E coli
Ecological niches
Environmental impact
Escherichia coli
Etiology
Expression vectors
flora
food chain
Food chains
Food webs
Gene transfer
Hemorrhage
horizontal gene transfer
Horizontal transfer
humans
Hygiene
Infectious diseases
Intestinal microflora
intestinal microorganisms
Life Sciences
Livestock
Medical Microbiology
Microbiology
Microbiomes
Microbiota
monitoring
Mycobacterium tuberculosis
Niches
One Health initiative
pathogens
Quorum sensing
resistance genes
Review
Review Article
Tuberculosis
Zoonoses
Livestock
Zoonosis
Half-lives of antibiotic
Gut microbiome
Antibiotic resistance
ISSN:0046-8991, 0973-7715
Online Access:Get full text
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Summary:Current scenario in communicable diseases has generated new era that identifies the “One health” approach to understand the sharing and management of etiological agents with its impact on ecosystem. Under this context the relevance of zoonotic diseases generates major concern. The indiscriminate and higher use of antibiotics in animal husbandry creates substantial pressure on the gut microbiome for development of resistance due to shorter generation time and high density. Thus, gut works as a bioreactor for the breeding of ARBs in this scenario and are continuously released in different niches. These ARBs transfer resistance genes among native flora through horizontal gene transfer events, vectors and quorum sensing. About 60% of infectious diseases in human are caused by zoonotic pathogens have potential to carry ARGs which could be transmitted to humans. The well documented zoonotic diseases are anthrax cause by Bacillus anthracis , bovine tuberculosis by Mycobacterium tuberculosis , brucellosis by Brucella abortus , and hemorrhagic colitis by Escherichia coli . Similarly, most of the antibiotics are not completely metabolized and released in unmetabolized forms which enters the food chain and affect various ecological niches through bioaccumulation. The persistence period of antibiotics ranges from < 1 to 3466 days in environment. The consequences of misusing the antibiotic in livestock and their fate in various ecological niches have been discussed in this review. Further the light sheds on antibiotics persistence and it biodegradation through different abiotic and biotic approaches in environment. The knowledge on personnel hygiene and strong surveillance system for zoonotic disease including ARBs transmission, prevention and control measures should be established to regulate the spread of AMR in the environment and subsequently to the human being through a food web.
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ISSN:0046-8991
0973-7715
DOI:10.1007/s12088-020-00860-z