The birth of piRNAs: how mammalian piRNAs are produced, originated, and evolved

PIWI-interacting RNAs (piRNAs), small noncoding RNAs 24–35 nucleotides long, are essential for animal fertility. They play critical roles in a range of functions, including transposable element suppression, gene expression regulation, imprinting, and viral defense. In mammals, piRNAs are the most ab...

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Veröffentlicht in:	Mammalian genome Jg. 33; H. 2; S. 293 - 311
Hauptverfasser:	Sun, Yu H., Lee, Brent, Li, Xin Zhiguo
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York Springer US 01.06.2022 Springer Nature B.V
Schlagworte:	adults animal fertility Animal Genetics and Genomics Animals biogenesis Biomedical and Life Sciences Biosynthesis Birth Cell Biology Chromatin DNA DNA Transposable Elements - genetics Epigenesis, Genetic Epigenetics Fertility fruits Gene expression gene expression regulation Gene regulation genome Genomics germ cells Human Genetics Imprinting Life Sciences Male Mammals Mammals - genetics Mice Nucleotides Post-transcription RNA processing RNA, Small Interfering - genetics Sexual dimorphism Testis - metabolism therapeutics transposons
ISSN:	0938-8990, 1432-1777, 1432-1777
Online-Zugang:	Volltext
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