Emerging Advances of Nanotechnology in Drug and Vaccine Delivery against Viral Associated Respiratory Infectious Diseases (VARID)

Viral-associated respiratory infectious diseases are one of the most prominent subsets of respiratory failures, known as viral respiratory infections (VRI). VRIs are proceeded by an infection caused by viruses infecting the respiratory system. For the past 100 years, viral associated respiratory epi...

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Vydáno v:	International Journal of Molecular Sciences Ročník 22; číslo 13; s. 6937
Hlavní autoři:	Seyfoori, Amir, Shokrollahi Barough, Mahdieh, Mokarram, Pooneh, Ahmadi, Mazaher, Mehrbod, Parvaneh, Sheidary, Alireza, Madrakian, Tayyebeh, Kiumarsi, Mohammad, Walsh, Tavia, McAlinden, Kielan D., Ghosh, Chandra C., Sharma, Pawan, Zeki, Amir A., Ghavami, Saeid, Akbari, Mohsen
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland MDPI AG 28.06.2021 MDPI
Témata:	2.1 Biological and endogenous factors Aetiology Antiviral Agents Antiviral Agents - chemistry Antiviral Agents - therapeutic use Antiviral drugs Biochemistry and cell biology Biodefense Bioengineering Biological Sciences Biotechnology Chemical Physics Chemical Sciences COVID-19 COVID-19 - immunology COVID-19 - pathology COVID-19 - therapy COVID-19 - virology Drug Carriers Drug Carriers - chemistry Emerging Infectious Diseases Genetics Good Health and Well Being Humans Immune System Immune System - metabolism Immunization Infection Infectious Diseases Influenza Lung Medicinal and Biomolecular Chemistry Medicine and Health Sciences Microbiology nano-vaccine Nanomedicine Nanotechnology Other Biological Sciences Other Chemical Sciences Pneumonia & Influenza Prevention respiratory disease Respiratory System Respiratory Tract Infections Respiratory Tract Infections - pathology Respiratory Tract Infections - therapy Respiratory Tract Infections - virology Review SARS-CoV-2 SARS-CoV-2 - isolation & purification Translational Medical Research Vaccine Related viral infection Viral infections Viral Vaccines Viral Vaccines - administration & dosage Viral Vaccines - chemistry Viral Vaccines - immunology Virus Diseases Virus Diseases - immunology Virus Diseases - pathology Virus Diseases - prevention & control Virus Diseases - therapy Viruses COVID-19 nanomedicine SARS-CoV-2 viral infection respiratory disease nano-vaccine
ISSN:	1422-0067, 1661-6596, 1422-0067
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Popis
Shrnutí:	Viral-associated respiratory infectious diseases are one of the most prominent subsets of respiratory failures, known as viral respiratory infections (VRI). VRIs are proceeded by an infection caused by viruses infecting the respiratory system. For the past 100 years, viral associated respiratory epidemics have been the most common cause of infectious disease worldwide. Due to several drawbacks of the current anti-viral treatments, such as drug resistance generation and non-targeting of viral proteins, the development of novel nanotherapeutic or nano-vaccine strategies can be considered essential. Due to their specific physical and biological properties, nanoparticles hold promising opportunities for both anti-viral treatments and vaccines against viral infections. Besides the specific physiological properties of the respiratory system, there is a significant demand for utilizing nano-designs in the production of vaccines or antiviral agents for airway-localized administration. SARS-CoV-2, as an immediate example of respiratory viruses, is an enveloped, positive-sense, single-stranded RNA virus belonging to the coronaviridae family. COVID-19 can lead to acute respiratory distress syndrome, similarly to other members of the coronaviridae. Hence, reviewing the current and past emerging nanotechnology-based medications on similar respiratory viral diseases can identify pathways towards generating novel SARS-CoV-2 nanotherapeutics and/or nano-vaccines.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 These authors have equal contributions.
ISSN:	1422-0067 1661-6596 1422-0067
DOI:	10.3390/ijms22136937