Host genetic control of gut microbiome composition

The gut microbiome plays a significant role in health and disease, and there is mounting evidence indicating that the microbial composition is regulated in part by host genetics. Heritability estimates for microbial abundance in mice and humans range from (0.05–0.45), indicating that 5–45% of inter-...

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Bibliographic Details
Published in:	Mammalian genome Vol. 32; no. 4; pp. 263 - 281
Main Authors:	Bubier, Jason A., Chesler, Elissa J., Weinstock, George M.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.08.2021 Springer Nature B.V
Subjects:	Abundance Animal Genetics and Genomics Animals Biomedical and Life Sciences Cell Biology Digestive system Disease disease control Gastrointestinal Microbiome - genetics Gene expression Genetic control Genetic Diseases, Inborn - genetics Genetic Diseases, Inborn - microbiology Genetic diversity Genetic engineering Genetic Predisposition to Disease Genetics Genome-wide association studies Genome-Wide Association Study Genomes Genotype & phenotype Gut microbiota Heritability Host-Pathogen Interactions - genetics Human Genetics Humans Intestinal microflora intestinal microorganisms Life Sciences Mice Mice, Knockout microbiome Microbiomes Microbiota phenotype Phenotypes RNA, Ribosomal, 16S - genetics Twin studies
ISSN:	0938-8990, 1432-1777, 1432-1777
Online Access:	Get full text
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