Earlier versus Later Start of Antiretroviral Therapy in HIV-Infected Adults with Tuberculosis

When to initiate antiretroviral therapy in patients with newly diagnosed HIV infection and TB has been debated. In this study from Cambodia, giving antiretrovirals 2 weeks after the start of TB therapy was superior to therapy begun at 8 weeks, with a decrease in mortality. Tuberculosis is a major ca...

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Vydané v:	The New England journal of medicine Ročník 365; číslo 16; s. 1471 - 1481
Hlavní autori:	Blanc, François-Xavier, Sok, Thim, Laureillard, Didier, Borand, Laurence, Rekacewicz, Claire, Nerrienet, Eric, Madec, Yoann, Marcy, Olivier, Chan, Sarin, Prak, Narom, Kim, Chindamony, Lak, Khemarin Kim, Hak, Chanroeurn, Dim, Bunnet, Sin, Chhun Im, Sun, Sath, Guillard, Bertrand, Sar, Borann, Vong, Sirenda, Fernandez, Marcelo, Fox, Lawrence, Delfraissy, Jean-François, Goldfeld, Anne E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Waltham, MA Massachusetts Medical Society 20.10.2011
Predmet:	Acquired immune deficiency syndrome Adult AIDS AIDS-Related Opportunistic Infections - drug therapy Anti-Retroviral Agents - administration & dosage Anti-Retroviral Agents - adverse effects Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Antitubercular Agents - therapeutic use Antiviral agents Biological and medical sciences CD4 antigen CD4 Lymphocyte Count Drug Administration Schedule Drug therapy Efavirenz Female Follow-Up Studies General aspects Hepatitis HIV HIV Infections - complications HIV Infections - drug therapy HIV Infections - mortality Human health and pathology Human immunodeficiency virus Human viral diseases Humans Immune reconstitution Immunosuppressive agents Infectious diseases Inflammation Kaplan-Meier Estimate Lamivudine Life Sciences Lymphocytes T Male Medical sciences Mortality Patients Pharmaceutical sciences Pharmacology Pharmacology. Drug treatments Santé publique et épidémiologie Stavudine Tuberculosis Tuberculosis - complications Tuberculosis - drug therapy Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load Human Immunopathology Antiretroviral agent AIDS Mycobacterial infection Immune deficiency Infection Medicine Chemotherapy Treatment Tuberculosis Viral disease Bacteriosis Adult Antiviral Comparative study
ISSN:	0028-4793, 1533-4406, 1533-4406
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