Mechanisms of climate change and related air pollution on the immune system leading to allergic disease and asthma

Climate change is considered the greatest threat to global health. Greenhouse gases as well as global surface temperatures have increased causing more frequent and intense heat and cold waves, wildfires, floods, drought, altered rainfall patterns, hurricanes, thunderstorms, air pollution, and windst...

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Vydáno v:Seminars in immunology Ročník 67; s. 101765
Hlavní autoři: Sampath, Vanitha, Aguilera, Juan, Prunicki, Mary, Nadeau, Kari C.
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Elsevier Ltd 01.05.2023
Témata:
Air Pollution
Allergy
Animals
Asthma
Asthma - immunology
Climate Change
Disasters
Humans
Hypersensitivity - immunology
Immune System
Pollen
Pollution
Wildfire
Climate change
Allergy
Wildfire
Pollution
Pollen
Asthma
ISSN:1044-5323, 1096-3618, 1096-3618
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Shrnutí:Climate change is considered the greatest threat to global health. Greenhouse gases as well as global surface temperatures have increased causing more frequent and intense heat and cold waves, wildfires, floods, drought, altered rainfall patterns, hurricanes, thunderstorms, air pollution, and windstorms. These extreme weather events have direct and indirect effects on the immune system, leading to allergic disease due to exposure to pollen, molds, and other environmental pollutants. In this review, we will focus on immune mechanisms associated with allergy and asthma-related health risks induced by climate change events. We will review current understanding of the molecular and cellular mechanisms by which the changing environment mediates these effects. •Fossil fuels are increasing greenhouse gas concentrations.•Greenhouse gases have increased global temperatures by 1.1 °C higher than in 1880.•CO2 levels are high at 421 ppm, levels last seen four million years ago.•Climate change is adversely affecting immune health.•Prevalence of allergies and asthma have increased with climate change.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
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co first authors
ISSN:1044-5323
1096-3618
1096-3618
DOI:10.1016/j.smim.2023.101765