Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study

Circulating lipids and insulin-like growth factor 1 (IGF-I) have been reliably associated with breast cancer. Observational studies suggest an interplay between lipids and IGF-I, however, whether these relationships are causal and if pathways from these phenotypes to breast cancer overlap is unclear...

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Vydané v:	Cancer epidemiology, biomarkers & prevention Ročník 30; číslo 12; s. 2207
Hlavní autori:	Tan, Vanessa Y, Bull, Caroline J, Biernacka, Kalina M, Teumer, Alexander, Richardson, Tom G, Sanderson, Eleanor, Corbin, Laura J, Dudding, Tom, Qi, Qibin, Kaplan, Robert C, Rotter, Jerome I, Friedrich, Nele, Völker, Uwe, Mayerle, Julia, Perks, Claire M, Holly, Jeff M P, Timpson, Nicholas J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.12.2021
Predmet:	Breast Neoplasms - blood Breast Neoplasms - genetics Causality Cholesterol, HDL - blood Cholesterol, LDL - blood Cross-Sectional Studies Female Genome-Wide Association Study Humans Insulin-Like Growth Factor I - genetics Mendelian Randomization Analysis Triglycerides - blood
ISSN:	1538-7755, 1538-7755
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